Omi/HtrA2 promotes cell death by binding and degrading the anti-apoptotic protein ped/pea-15

Journal of Biological Chemistry

Volumn 279, Issue 45, 2004, Pages 46566-46572

  Trencia, Alessandra ^a   Fiory, Francesca ^a   Maitan, Maria Alessandra ^a   Vito, Pasquale ^b   Barbagallo, Alessia Paola Maria ^a   Perfetti, Anna ^a   Miele, Claudia ^a   Ungaro, Paola ^a   Oriente, Francesco ^a   Cilenti, Lucia ^c   Zervos, Antonis S ^c   Formisano, Pietro ^a   Beguinot, Francesco ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF SANNIO   (Italy)

^c UNIVERSITY OF CENTRAL FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BIODEGRADATION; BODY FLUIDS; CHEMICAL BONDS; PROTEINS;

APOPTOSIS; CELL DEATH; CYTOPLASM;

CELLS;

APOPTOSIS INHIBITOR; CASPASE 3; CASPASE INHIBITOR; CYTOPLASM PROTEIN; MITOCHONDRIAL PROTEIN; PROTEIN OMI/HTRA2; PROTEIN PED/PEA 15; PROTEIN UCF 101; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

APOPTOSIS; ARTICLE; CELL DEATH; CELL LEVEL; CELL SURVIVAL; CYTOPLASM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRION; PRECIPITATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; RADIATION EXPOSURE; ULTRAVIOLET RADIATION;

APOPTOSIS; BETA-GALACTOSIDASE; BLOTTING, WESTERN; CASPASE 3; CASPASES; CELL LINE; CYTOPLASM; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE LIBRARY; GLUTATHIONE TRANSFERASE; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PHOSPHOPROTEINS; PLASMIDS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES; SUBCELLULAR FRACTIONS; TRANSFECTION; TWO-HYBRID SYSTEM TECHNIQUES; ULTRAVIOLET RAYS; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

PISUM SATIVUM;

EID: 8744250363     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M406317200     Document Type: Article

References (35)

1. Cryns, V., and Yuan, J. (1998) Genes Dev. 12, 1551-1570
2. Thornberry, N. A., and Lazebnik, Y., (1998) Science 281, 1312-1316
3. Nagata, S. (1997) Cell 88, 355-365
4. Wang, X. (2001) Genes Dev. 15, 2922-2933
5. Danziger, N., Yokoyama, M., Jay, T., Cordier, J., Glowinski, J., and Chneiweiss, H. (1995) J. Neurochem. 64, 1016-1025
6. Condorelli, G., Vigliotta, G., Iavarone, C., Caruso, M., Tocchetti, C. G., Andreozzi, F., Cafieri, A., Tecce, M. F., Formisano, P., Beguinot, L., and Beguinot, F. (1998) EMBO J. 17, 3858-3866
7. Kitsberg, D., Formstecher, E., Fauquet, M., Kubes, M., Cordier, J., Canton, B., Pan, G., Rolli, M., Glowinski, J., and Chneiweiss, H. (1999) J. Neurosci. 19, 8244-8251
8. Condorelli, G., Vigliotta, G., Cafieri, A., Trencia, A., Andalo, P., Oriente, F., Miele, C., Caruso, M., Formisano, P., and Beguinot, F. (1999) Oncogene 18, 4409-4415
9. Condorelli, G., Trencia, A., Vigliotta, G., Perfetti, A., Goglia, U., Cassese, A., Musti, A. M., Miele, C., Santopietro, S., Formisano, P., and Beguinot, F. (2002) J. Biol. Chem. 277, 11013-11018
10. Hao, C., Beguinot, F., Condorelli, G., Trencia, A., Van Meir, E. G., Yong, V. W., Parney, I. F., Roa, W. H., and Petruk, K. C. (2001) Cancer Res. 61, 1162-1170
11. Gray, C. W., Ward, R. V., Karran, E., Turconi, S., Rowles, A., Viglienghi, D., Southan, C., Barton, A., Fantom, K. G., West, A., Savopoulos, J., Hassan, N. J., Clinkenbeard, H., Hanning, C., Amegadzie, B., Davis, J. B., Dingwall, C., Livi, G. P., and Creasy, C. L. (2000) Eur. J. Biochem. 267, 5699-5710
12. Faccio, L., Fusco, C., Chen, A., Martinotti, S., Bonventre, J. V., and Zervos, A. S. (2000) J. Biol. Chem. 275, 2581-2588
13. Yang, Q. H., Church-Hajduk, R., Ren, J., Newton, M. L., and Du, C. (2003) Genes Dev. 17, 487-496
14. Liu, Z., Sun, C., Olejniczak, E. T., Meadows, R. P., Beta, S. F., Oost, T., Herrmann, J., Wu, J. C., and Fesik, S. W. (2000) Nature 408, 1004-1008
15. Wu, G., Chai, J., Suber, T. L., Wu, J. W., Du, C., Wang, X., and Shi, Y. (2000) Nature 408, 1008-1012
16. Srinivasula, S. M., Hegde, R., Saleh, A., Datta, P., Shiozaki, E., Chai, J., Lee, R. A., Robbins, P. D., Fernandes-Alnemri, T., Shi, Y., and Alnemri, E. S. (2001) Nature 410, 112-116
17. Li, W., Srinivasula, S. M., Chai, J., Li, P., Wu, J. W., Zhang, Z., Alnemri, E. S., and Shi, Y. (2002) Nat. Struct. Biol. 9, 436-441
18. Suzuki, Y., Imai, Y., Nakayama, H., Takahashi, K., Takio, K., and Takahashi, R. (2001) Mol. Cell 8, 613-621
19. Hegde, R., Srinivasula, S. M., Zhang, Z., Wassell, R., Mukattash, R., Cilenti, L., DuBois, G., Lazebnik, Y., Zervos, A. S., Fernandes-Alnemri, T., and Alnemri, E. S. (2002) J. Biol. Chem. 277, 432-438
20. Martins, L. M., Iaccarino, I., Tenev, T., Gschmeissner, S., Totty, N. F., Lemoine, N. R., Savopoulos, J., Gray, C. W., Creasy, C. L., Dingwall, C., and Downward, J. (2002) J. Biol. Chem. 277, 439-444
21. Guiet, C., and Vito, P. (2000) J. Cell Biol. 148, 1131-1140
22. Gietz, D., St. Jean, A., Woods, R. A., and Schiestl, R. H. (1992) Nucleic Acids Res. 20, 1425
23. Miller, J. H. (1972) Experiments in Molecular Genetics, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
24. Ruvolo, P. P., Deng, X., Carr, B. K., and May, W. S. (1998) J. Biol. Chem. 273, 25436-25442
25. Wang, H. G., Rapp, U. R., and Reed, J. C. (1996) Cell 87, 629-638
26. Hovius, R., Lambrechts, H., Nicolay, K., and de Kruijff, B. (1990) Biochim. Biophys. Acta. 1021, 217-226
27. Gateau, O., Morelis, R., and Louisot, P. (1978) Eur. J. Biochem. 88, 613-622
28. Pennington, R. (1961) Biochem. J. 80, 649-654
29. Trencia, A., Perfetti, A., Cassese, A., Vigliotta, G., Miele, C., Oriente, F., Santopietro, S., Giacco, F., Condorelli, G., Formisano, P., and Beguinot, F. (2003) Mol. Cell. Biol. 23, 4511-4521
30. van Loo, G., van Gurp, M., Depuydt, B., Srinivasula, S. M., Rodriguez, I., Alnemri, E. S., Gevaert, K., Vandekerckhove, J., Declercq, W., and Vandenabeele, P. (2002) Cell Death Differ. 9, 20-26
31. Condorelolli, G., Vigliotta, G., Trencia, A., Maitan, M. A., Caruso, M., Miele, C., Oriente, F., Santopietro, S., Formisano, P., and Beguinot, F. (2001) Diabetes 50, 1244-1252
32. Cilenti, L., Lee, Y., Hess, S., Srinivasula, S., Park, K. M., Junqueira, D., Davis, H., Bonventre, J. V., Alnemri, E. S., and Zervos, A. S. (2003) J. Biol. Chem. 278, 1489-1494
33. Jones, J. M., Datta, P., Srinivasula, S. M., Ji, W, Gupta, S., Zhang, Z., Davies, E., Hajnoczky, G., Saunders, T. L., Van Keuren, M. L., Fernandes-Alnemri, T., Meisler, M. H., and Alnemri, E. S. (2003) Nature 425, 721-727
34. Srinivasula, S. M., Gupta, S., Datta, P., Zhang, Z., Hegde, R., Cheong, N., Fernandes-Alnemri, T., and Alnemri, E. S. (2003) J. Biol. Chem. 278, 31469-31472
35. Formstecher, E., Ramos, J. W., Fauquet, M., Calderwood, D. A., Hsieh, J. C., Canton, B., Nguyen, X. T., Barnier, J. V., Camonis, J., Ginsberg, M. H., and Chneiweiss, H. (2001) Dev. Cell 1, 239-250