Deciphering enzymes: Genetic selection as a probe of structure and mechanism

European Journal of Biochemistry

Volumn 271, Issue 9, 2004, Pages 1630-1637

  Woycechowsky, Kenneth J ^a   Hilvert, Donald ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Chorismate mutase; Functional selection; Protein engineering; Protein folding

Indexed keywords

ANTIBIOTIC AGENT; AZTREONAM; BETA LACTAMASE; CHORISMATE MUTASE; DNA POLYMERASE; ENZYME;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ANTIBIOTIC RESISTANCE; CATALYSIS; CHEMICAL BOND; CONFORMATION; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STRUCTURE; GENE LIBRARY; GENETIC SELECTION; METHANOCOCCUS JANNASCHII; METHODOLOGY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE; SHORT SURVEY; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS;

BINDING SITES; CATALYSIS; CHORISMATE MUTASE; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; SELECTION (GENETICS); STRUCTURE-ACTIVITY RELATIONSHIP;

METHANOCALDOCOCCUS JANNASCHII; METHANOCOCCUS;

EID: 2342562489     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.2004.04073.x     Document Type: Short Survey

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