Probing enzyme quaternary structure by combinatorial mutagenesis and selection

Protein Science

Volumn 7, Issue 8, 1998, Pages 1757-1767

  Macbeath, Gavin ^a   Kast, Peter ^a   Hilvert, Donald ^a,b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b ETH ZURICH   (Switzerland)

Author keywords

Chorismate mutase; Directed evolution; Domain swapping; Escherichia coli; Four helix bundle; Genetic selection; Hinge loop; Quaternary structure

Indexed keywords

CHORISMATE MUTASE; PREPHENATE DEHYDRATASE;

ARTICLE; COMPUTER MODEL; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME STABILITY; ENZYME STRUCTURE; ESCHERICHIA COLI; GENETIC SELECTION; MOLECULAR EVOLUTION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN QUATERNARY STRUCTURE; STRUCTURE ANALYSIS;

EID: 0032456057     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1002/pro.5560070810     Document Type: Article

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