-
1
-
-
0014965307
-
Multiple forms of human brain mitochondrial monoamine oxidase
-
Collins, G.G., Sandler, M., Williams, E.D., Youdim, M.B. Multiple forms of human brain mitochondrial monoamine oxidase. Nature 1970, 225:817-20.
-
(1970)
Nature
, vol.225
, pp. 817-820
-
-
Collins, G.G.1
Sandler, M.2
Williams, E.D.3
Youdim, M.B.4
-
2
-
-
0015272059
-
Multiple forms of monoamine oxidase in intact mitochondria as characterized by selective inhibitors and thermal stability: A comparison of eight mammalian species
-
Squires, R.F. Multiple forms of monoamine oxidase in intact mitochondria as characterized by selective inhibitors and thermal stability: a comparison of eight mammalian species. Adv Biochem Psychopharmacol 1972, 5: 355-7.
-
(1972)
Adv Biochem Psychopharmacol
, vol.5
, pp. 355-357
-
-
Squires, R.F.1
-
3
-
-
0020662487
-
The deamination of dopamine by human brain monoamine oxidase
-
O'Carroll, A.M., Fowler, C.J., Phillip, J.P., Tobia, I., Tipton, K.F. The deamination of dopamine by human brain monoamine oxidase. Specificity for the two forms in seven brain regions. Naunyn Schmiedebergs Arch Pharmacol 1983, 322: 198-207.
-
(1983)
Specificity for the Two Forms in Seven Brain Regions. Naunyn Schmiedebergs Arch Pharmacol
, vol.322
, pp. 198-207
-
-
O'Carroll, A.M.1
Fowler, C.J.2
Phillip, J.P.3
Tobia, I.4
Tipton, K.F.5
-
4
-
-
0015274536
-
Some puzzling pharmacological effects of monoamine oxidase inhibitors
-
Knoll and Magyar. Some puzzling pharmacological effects of monoamine oxidase inhibitors. Adv Biochem Psychopharmacol 1972, 5: 393-408.
-
(1972)
Adv Biochem Psychopharmacol
, vol.5
, pp. 393-408
-
-
Knoll1
Magyar2
-
5
-
-
0016414699
-
The potentiation of the anti akinetic effect after L-dopa treatment by an inhibitor of MAO-B, Deprenil
-
Birkmayer, W., Riederer, P., Youdim, M.B., Linauer, W. The potentiation of the anti akinetic effect after L-dopa treatment by an inhibitor of MAO-B, Deprenil. J Neural Transm 1975, 36: 303-26.
-
(1975)
J Neural Transm
, vol.36
, pp. 303-326
-
-
Birkmayer, W.1
Riederer, P.2
Youdim, M.B.3
Linauer, W.4
-
6
-
-
0017345412
-
Implications of combined treatment with 'Madopar' and L-deprenil in Parkinson's disease. A long-term study
-
Birkmayer, W., Riederer, P., Ambrozi, L., Youdim, M.B. Implications of combined treatment with 'Madopar' and L-deprenil in Parkinson's disease. A long-term study. Lancet 1977, 1: 439-43.
-
(1977)
Lancet
, vol.1
, pp. 439-443
-
-
Birkmayer, W.1
Riederer, P.2
Ambrozi, L.3
Youdim, M.B.4
-
7
-
-
0017729733
-
Deprenyl in Parkinson's disease
-
Lees, A.J., Shaw, K.M., Kohout, L.J. et al. Deprenyl in Parkinson's disease. Lancet 1977, 2: 791-5.
-
(1977)
Lancet
, vol.2
, pp. 791-795
-
-
Lees, A.J.1
Shaw, K.M.2
Kohout, L.J.3
-
8
-
-
0006093024
-
Selegiline and Parkinson's disease
-
Parkinson Study Group (Datatop). Selegiline and Parkinson's disease. N Engl J Med 1989, 321: 1364-71.
-
(1989)
N Engl J Med
, vol.321
, pp. 1364-1371
-
-
-
9
-
-
0022365018
-
Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease: A long-term study
-
Birkmayer, W., Knoll, J., Riederer, P., Youdim, M.B., Hars, V., Marton, J. Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease: A long-term study. J Neural Transm 1985, 64: 113-27.
-
(1985)
J Neural Transm
, vol.64
, pp. 113-127
-
-
Birkmayer, W.1
Knoll, J.2
Riederer, P.3
Youdim, M.B.4
Hars, V.5
Marton, J.6
-
10
-
-
0006122290
-
Selegiline in Parkinson's Disease: An update
-
Riederer, P., Rinne U.K. Selegiline in Parkinson's Disease: An update. Mov Disords 1992, 8 (Suppl. 1): 51-44.
-
(1992)
Mov Disords
, vol.8
, Issue.SUPPL. 1
, pp. 51-144
-
-
Riederer, P.1
Rinne, U.K.2
-
11
-
-
0017186551
-
The action of acetylenic inhibitors on mitochondrial monoamine oxidase: Structure of the flavin site in the inhibited enzyme
-
Elsevier, Amsterdam
-
Maycock, A.L., Abeles, R.H., Salach, J., Singer, T.P. The action of acetylenic inhibitors on mitochondrial monoamine oxidase: Structure of the flavin site in the inhibited enzyme. Ciba Foundation Symposium, Elsevier, Amsterdam 1976, 39: 33-49.
-
(1976)
Ciba Foundation Symposium
, vol.39
, pp. 33-49
-
-
Maycock, A.L.1
Abeles, R.H.2
Salach, J.3
Singer, T.P.4
-
13
-
-
0018068203
-
Amphetamine and 2-phenylethylamine in post mortem Parkinson brains after I-deprenyl administration
-
Reynolds, G.P., Riederer, P., Sandler, N.R., Jellinger, K., Seemali, D. Amphetamine and 2-phenylethylamine in post mortem Parkinson brains after I-deprenyl administration. J Neural Transm 1978, 3: 271-8.
-
(1978)
J Neural Transm
, vol.3
, pp. 271-278
-
-
Reynolds, G.P.1
Riederer, P.2
Sandler, N.R.3
Jellinger, K.4
Seemali, D.5
-
14
-
-
0016829477
-
Effects of monoamine oxidase inhibition by clorgyline, deprenil or tranylcypromine on 5-hydroxytryptamine concentrations in rat brain and hyperactivity following subsequent tryptophan administration
-
Green, A.R., Youdim, M.B. Effects of monoamine oxidase inhibition by clorgyline, deprenil or tranylcypromine on 5-hydroxytryptamine concentrations in rat brain and hyperactivity following subsequent tryptophan administration. Br J Pharmacol 1975, 55: 415-22.
-
(1975)
Br J Pharmacol
, vol.55
, pp. 415-422
-
-
Green, A.R.1
Youdim, M.B.2
-
15
-
-
0018139965
-
Evidence that deprenyl, a type B monoamine oxidase inhibitor is an indirectly acting sympathomimetic amine
-
Simpson, L.L. Evidence that deprenyl, a type B monoamine oxidase inhibitor is an indirectly acting sympathomimetic amine. Biochem Pharmacol 1978, 27: 1591-5.
-
(1978)
Biochem Pharmacol
, vol.27
, pp. 1591-1595
-
-
Simpson, L.L.1
-
16
-
-
0019462668
-
Tyramine antagonistic properties of AGN 1135, an irreversible inhibitor of monoamine oxidase type B
-
Finberg, J.P.M., Tenne, M., Youdim, M.B.H. Tyramine antagonistic properties of AGN 1135, an irreversible inhibitor of monoamine oxidase type B. Br J Pharmacol 1981, 73: 65-74.
-
(1981)
Br J Pharmacol
, vol.73
, pp. 65-74
-
-
Finberg, J.P.M.1
Tenne, M.2
Youdim, M.B.H.3
-
17
-
-
84878744562
-
-
R-Enantiomers of N-propargyl-aminoindan compounds. Their preparation and pharmaceutical composition containing them. US Patent 1995, 5: 457, 133; NCI 1420, 1-8
-
Youdim, M.B.H., Finberg, J.P.M., Levy, R. et al. R-Enantiomers of N-propargyl-aminoindan compounds. Their preparation and pharmaceutical composition containing them. US Patent 1995, 5: 457, 133; NCI 1420, 1-8.
-
-
-
Youdim, M.B.H.1
Finberg, J.P.M.2
Levy, R.3
-
18
-
-
0031596711
-
(R) (+)-N-propargyl-1-aminoindan (rasagiline) and derivatives: Highly selective and potent inhibitors of monoamine oxidase B
-
Sterling, J., Veinberg, A., Lerner, D. et al. (R) (+)-N-propargyl-1- aminoindan (rasagiline) and derivatives: Highly selective and potent inhibitors of monoamine oxidase B. J Neural Transm Suppl 1998, 52: 301-5.
-
(1998)
J Neural Transm Suppl
, vol.52
, pp. 301-305
-
-
Sterling, J.1
Veinberg, A.2
Lerner, D.3
-
19
-
-
0037153195
-
Novel dual inhibitors of AChE and MAO derived from hydroxy aminoindan and phenethylamine as potential treatment for Alzheimer's disease
-
Sterling, J., Herzig, Y., Goren, T. et al. Novel dual inhibitors of AChE and MAO derived from hydroxy aminoindan and phenethylamine as potential treatment for Alzheimer's disease. J Med Chem 2002, 45: 5260-79.
-
(2002)
J Med Chem
, vol.45
, pp. 5260-5279
-
-
Sterling, J.1
Herzig, Y.2
Goren, T.3
-
20
-
-
0000031465
-
Selective inhibition of monoamine oxidase type B by propargyl-containing drugs
-
Sabbagh, A., Youdim, M.B.H. Selective inhibition of monoamine oxidase type B by propargyl-containing drugs. Israel J Med Sci 1978, 14: 1097.
-
(1978)
Israel J Med Sci
, vol.14
, pp. 1097
-
-
Sabbagh, A.1
Youdim, M.B.H.2
-
21
-
-
0019429465
-
Selective "suicide" acetylenic and reversible inhibitors of monoamine oxidase A and B
-
Kalir, A., Sabbagh, A., Youdim, M.B.H. Selective "suicide" acetylenic and reversible inhibitors of monoamine oxidase A and B. Br J Pharmacol 1981, 73: 55-64.
-
(1981)
Br J Pharmacol
, vol.73
, pp. 55-64
-
-
Kalir, A.1
Sabbagh, A.2
Youdim, M.B.H.3
-
22
-
-
0035130289
-
Rasagiline [N-Propargyl-1R(+)-aminoindant], a selective and potent inhibitor of mitochondrial monoamine oxidase B
-
Youdim, M.B.H., Gross, A., Finberg, J.P.M. Rasagiline [N-Propargyl-1R(+)-aminoindant], A selective and potent inhibitor of mitochondrial monoamine oxidase B. Br J Pharmacol 2001, 132: 500-6.
-
(2001)
Br J Pharmacol
, vol.132
, pp. 500-506
-
-
Youdim, M.B.H.1
Gross, A.2
Finberg, J.P.M.3
-
23
-
-
0023209438
-
MAO type B inhibitors as adjunct to L-dopa therapy
-
Youdim, M.B., Finberg, J.P. MAO type B inhibitors as adjunct to L-dopa therapy. Adv Neurol 1987, 45: 127-36.
-
(1987)
Adv Neurol
, vol.45
, pp. 127-136
-
-
Youdim, M.B.1
Finberg, J.P.2
-
24
-
-
0031596702
-
Increased striatal dopamine production from L-DOPA following selective inhibition of monoamine oxidase B by R(+)-N-propargyl-1-aminoindan (rasagiline) in the monkey
-
Finberg, J.P., Wang, J., Bankiewicz, K., Harvey-White, J., Kopin, I.J., Goldstein, D.S. Increased striatal dopamine production from L-DOPA following selective inhibition of monoamine oxidase B by R(+)-N-propargyl-1-aminoindan (rasagiline) in the monkey. J Neural Transm 1998, 52: 279-85.
-
(1998)
J Neural Transm
, vol.52
, pp. 279-285
-
-
Finberg, J.P.1
Wang, J.2
Bankiewicz, K.3
Harvey-White, J.4
Kopin, I.J.5
Goldstein, D.S.6
-
25
-
-
0032609072
-
Pharmacology of rasagiline (N-propargyl-1R-aminoindan)
-
Finberg, J.P., Lamensdorf, I., Weinstock, M., Schwartz, M., Youdim, M.B. Pharmacology of rasagiline (N-propargyl-1R-aminoindan). Adv Neurol 1999, 80: 495-9.
-
(1999)
Adv Neurol
, vol.80
, pp. 495-499
-
-
Finberg, J.P.1
Lamensdorf, I.2
Weinstock, M.3
Schwartz, M.4
Youdim, M.B.5
-
26
-
-
0036894795
-
A controlled trial of rasagiline in early Parkinson disease: The TEMPO Study
-
Parkinson Study Group. A controlled trial of rasagiline in early Parkinson disease: The TEMPO Study. Arch Neurol 2002, 59: 1937-43.
-
(2002)
Arch Neurol
, vol.59
, pp. 1937-1943
-
-
-
27
-
-
2342655732
-
A controlled, randomized, delayed-start study of rasagiline in early Parkinson disease
-
Parkinson Study Group. A controlled, randomized, delayed-start study of rasagiline in early Parkinson disease. Arch Neurol 2004, 61: 561-6.
-
(2004)
Arch Neurol
, vol.61
, pp. 561-566
-
-
-
28
-
-
0022401727
-
Modification of blood pressure and nictitating membrane response to sympathetic amines by selective monoamine oxidase inhibitors of types a and B in the cat
-
Finberg, J.P.M., Youdim, M.B.H. Modification of blood pressure and nictitating membrane response to sympathetic amines by selective monoamine oxidase inhibitors of types A and B in the cat. Br J Pharmacol 1985, 85: 541-6.
-
(1985)
Br J Pharmacol
, vol.85
, pp. 541-546
-
-
Finberg, J.P.M.1
Youdim, M.B.H.2
-
29
-
-
0034519674
-
Rasagiline mesylate, a new MAO-B inhibitor for the treatment of Parkinson's disease: A double-blind study as adjunctive therapy to levodopa
-
Rabey, J.M., Sagi, I., Huberman, M. et al.; Rasagiline Study Group. Rasagiline mesylate, a new MAO-B inhibitor for the treatment of Parkinson's disease: A double-blind study as adjunctive therapy to levodopa. Clin Neuropharmacol 2000, 23: 324-30.
-
(2000)
Clin Neuropharmacol
, vol.23
, pp. 324-330
-
-
Rabey, J.M.1
Sagi, I.2
Huberman, M.3
-
30
-
-
33544464417
-
-
unpublished data
-
Largo Study Group, 2003 (unpublished data).
-
(2003)
-
-
-
31
-
-
13444302612
-
A randomized placebo-controlled trial of rasagiline in levodopa-treated patients with Parksinson disease and motor fluctuations. The PRESTO Study
-
Parkinson Study Group. A randomized placebo-controlled trial of rasagiline in levodopa-treated patients with Parksinson disease and motor fluctuations. The PRESTO Study. Arch Neurol 2005, 62: 241-8.
-
(2005)
Arch Neurol
, vol.62
, pp. 241-248
-
-
-
33
-
-
33544457355
-
Monoamine oxidases
-
Weiner, N., Trendelenburg, U. (Eds.). Springer-Verlag, Berlin
-
Youdim, M.B.H., Finberg, J.P.M., Tipton, K.F. Monoamine Oxidases. In: Weiner, N., Trendelenburg, U. (Eds.). Handbook of Experimental Pharmacology Catecholamine II. Springer-Verlag, Berlin 1998, pp. 415-58.
-
(1998)
Handbook of Experimental Pharmacology Catecholamine II
, pp. 415-458
-
-
Youdim, M.B.H.1
Finberg, J.P.M.2
Tipton, K.F.3
-
34
-
-
0015186769
-
The covalently bound flavin of hepatic monoamine oxidase I. Isolation and sequence of a flavin peptide and evidence for binding to the 8-position
-
Kearney, FB., Salach, J.I., Walker, W.H. et al. The covalently bound flavin of hepatic monoamine oxidase I. Isolation and sequence of a flavin peptide and evidence for binding to the 8-position. Eur J Biochem 1971, 24: 321-7.
-
(1971)
Eur J Biochem
, vol.24
, pp. 321-327
-
-
Kearney, F.B.1
Salach, J.I.2
Walker, W.H.3
-
35
-
-
0024042954
-
CDNA cloning of human liver monoamine oxidase a and B: Molecular basis of differences in enzymatic properties
-
Bach, A.W.J., Lan, N.C., Johnson, D.L. et al. cDNA cloning of human liver monoamine oxidase A and B: Molecular basis of differences in enzymatic properties. Proc Nat Acad Sci USA 1988, 85: 4934-8.
-
(1988)
Proc Nat Acad Sci USA
, vol.85
, pp. 4934-4938
-
-
Bach, A.W.J.1
Lan, N.C.2
Johnson, D.L.3
-
36
-
-
0017170101
-
Cysteinyl flavin in monoamine oxidase from the central nervous system
-
Elsevier, Amsterdam
-
Salach, J., Singer, T.P., Yaunobu, K.T., Monamura, N., Youdim, M.B.H. Cysteinyl flavin in monoamine oxidase from the central nervous system. Ciba Foundation Symposium, Elsevier, Amsterdam 1976, 39: 49-57.
-
(1976)
Ciba Foundation Symposium
, vol.39
, pp. 49-57
-
-
Salach, J.1
Singer, T.P.2
Yaunobu, K.T.3
Monamura, N.4
Youdim, M.B.H.5
-
37
-
-
0015690527
-
The oestrous cycle and monoamine oxidase activity
-
Holzbauer, M., Youdim, M.B. The oestrous cycle and monoamine oxidase activity. Br J Pharmacol 1973, 48: 600-8.
-
(1973)
Br J Pharmacol
, vol.48
, pp. 600-608
-
-
Holzbauer, M.1
Youdim, M.B.2
-
38
-
-
0027981209
-
Slow recovery of human brain MAO B after deprenyl (selegiline) withdrawal
-
Fowler, J.S., Volkow, N.D., Logan, J. et al. Slow recovery of human brain MAO B after deprenyl (selegiline) withdrawal. Synapse 1994, 18: 86-93.
-
(1994)
Synapse
, vol.18
, pp. 86-93
-
-
Fowler, J.S.1
Volkow, N.D.2
Logan, J.3
-
39
-
-
0024556215
-
Steroid regulation of monoamine oxidase activity in the adrenal medulla
-
Youdim, M.B., Banerjee, D.K., Keiner, K., Offutt, L., Pollard, H.B. Steroid regulation of monoamine oxidase activity in the adrenal medulla. FASEB J 1989, 3: 1753-9.
-
(1989)
FASEB J
, vol.3
, pp. 1753-1759
-
-
Youdim, M.B.1
Banerjee, D.K.2
Keiner, K.3
Offutt, L.4
Pollard, H.B.5
-
40
-
-
0027496797
-
The relevance of glial monoamine oxidase-B and polyamines to the action of selegiline in Parkinson's disease
-
Youdim, M.B., Riederer, P. The relevance of glial monoamine oxidase-B and polyamines to the action of selegiline in Parkinson's disease. Mov Disord 1993, 8 (Suppl. 1): S8-S13.
-
(1993)
Mov Disord
, vol.8
, Issue.SUPPL. 1
-
-
Youdim, M.B.1
Riederer, P.2
-
41
-
-
0036162584
-
Rat striatal monoamine oxidase-B inhibition by i-deprenyl and rasagiline: Its relationship to 2-phenylethylamine-induced stereotypy and Parkinson's disease
-
Youdim, M.B., Tipton, K.F. Rat striatal monoamine oxidase-B inhibition by i-deprenyl and rasagiline: Its relationship to 2-phenylethylamine-induced stereotypy and Parkinson's disease. Parkinsonism Relat Disord 2002, 8: 247-53.
-
(2002)
Parkinsonism Relat Disord
, vol.8
, pp. 247-253
-
-
Youdim, M.B.1
Tipton, K.F.2
-
42
-
-
0034941767
-
The anti-Parkinson drug rasagiline and its cholinesterase inhibitor derivatives exert neuroprotection unrelated to MAO inhibition in cell culture and in vivo
-
Youdim, M.B.H., Wadia, A., Tatton, N.A., Weinstock, M. The anti-Parkinson drug rasagiline and its cholinesterase inhibitor derivatives exert neuroprotection unrelated to MAO inhibition in cell culture and in vivo. Ann NY Acad Sci 2001, 939: 450-8.
-
(2001)
Ann NY Acad Sci
, vol.939
, pp. 450-458
-
-
Youdim, M.B.H.1
Wadia, A.2
Tatton, N.A.3
Weinstock, M.4
-
43
-
-
0031596704
-
Chronic TVP-1012 (rasagiline) dose-activity response of monoamine oxidases a and B in the brain of the common marmoset
-
Gotz, M.E., Breithaupt, W., Sautter, J. et al. Chronic TVP-1012 (rasagiline) dose-activity response of monoamine oxidases A and B in the brain of the common marmoset. J Neural Transm 1998, 52(Suppl.): 271-8.
-
(1998)
J Neural Transm
, vol.52
, Issue.SUPPL.
, pp. 271-278
-
-
Gotz, M.E.1
Breithaupt, W.2
Sautter, J.3
-
44
-
-
0022496317
-
Monoamine oxidase activity and monoamine metabolism in brains of parkinsonian patients treated with I-deprenyl
-
Riederer, P., Youdim, M.B. Monoamine oxidase activity and monoamine metabolism in brains of parkinsonian patients treated with I-deprenyl. J Neurochem 1986, 46: 1359-65.
-
(1986)
J Neurochem
, vol.46
, pp. 1359-1365
-
-
Riederer, P.1
Youdim, M.B.2
-
45
-
-
0017755902
-
Evidence for dopamine deamination by both type a and type B monoamine oxidase in rat brain in vivo and for degree of inhibition of enzyme necessary for increased function and activity of dopamine and 5-hydroxytryptamine
-
Green, A.R., Tordoff, A., Mitchel, B., Youdim, M.B.H. Evidence for dopamine deamination by both type A and type B monoamine oxidase in rat brain in vivo and for degree of inhibition of enzyme necessary for increased function and activity of dopamine and 5-hydroxytryptamine. Br J Pharmacol 1977, 60: 343-9.
-
(1977)
Br J Pharmacol
, vol.60
, pp. 343-349
-
-
Green, A.R.1
Tordoff, A.2
Mitchel, B.3
Youdim, M.B.H.4
-
46
-
-
0023174117
-
Localization of MAO-A and MAO-B in human brain: A step in understanding the therapeutic action of L-deprenyl
-
Riederer, P., Konradi, C., Schay, V. et al. Localization of MAO-A and MAO-B in human brain: A step in understanding the therapeutic action of L-deprenyl. Adv Neurol 1986, 45: 111-8.
-
(1986)
Adv Neurol
, vol.45
, pp. 111-118
-
-
Riederer, P.1
Konradi, C.2
Schay, V.3
-
47
-
-
0015270743
-
Neuronal monoamine oxidase: Specific enzyme types and their rates of formation
-
Neff, N.H., Gordis, C. Neuronal monoamine oxidase: Specific enzyme types and their rates of formation. Adv Biochem Psychopharmacol 1972, 5: 307-24.
-
(1972)
Adv Biochem Psychopharmacol
, vol.5
, pp. 307-324
-
-
Neff, N.H.1
Gordis, C.2
-
48
-
-
0018844749
-
The turnover of the a and B-forms of monoamine oxidase in rat liver
-
Della Corte, L., Tipton, K.F. The turnover of the A and B-forms of monoamine oxidase in rat liver. Biochem Pharmacol 1980, 29: 811-5.
-
(1980)
Biochem Pharmacol
, vol.29
, pp. 811-815
-
-
Della Corte, L.1
Tipton, K.F.2
-
49
-
-
0036914093
-
Pharmacological properties of the anti-Parkinson drug rasagiline, modification of endogenous brain amines, reserpine reversal, serotonergic and dopaminergic behaviours
-
Finberg, J.P., Youdim, M.B. Pharmacological properties of the anti-Parkinson drug rasagiline, modification of endogenous brain amines, reserpine reversal, serotonergic and dopaminergic behaviours. Neuropharmacology 2002, 43: 1110-18.
-
(2002)
Neuropharmacology
, vol.43
, pp. 1110-1118
-
-
Finberg, J.P.1
Youdim, M.B.2
-
50
-
-
0019944455
-
Relationship between tyramine potentiation and selective inhibition of monoamine oxidase types a and B in the rat vas deferens
-
Finberg, J.P., Tenne, M. Relationship between tyramine potentiation and selective inhibition of monoamine oxidase types A and B in the rat vas deferens. Br J Pharmacol 1982, 77: 13-21.
-
(1982)
Br J Pharmacol
, vol.77
, pp. 13-21
-
-
Finberg, J.P.1
Tenne, M.2
-
51
-
-
0345308381
-
Rasagiline - An anti-Parkinson drug with neuroprotective activity
-
Youdim, M.B.H. Rasagiline - An anti-Parkinson drug with neuroprotective activity. Fut Drug Expert Neurotherap Rev 2003, 3: 737-49.
-
(2003)
Fut Drug Expert Neurotherap Rev
, vol.3
, pp. 737-749
-
-
Youdim, M.B.H.1
-
52
-
-
0029832455
-
Effect of long-term treatment with selective monoamine oxidase a and B inhibitors on dopamine release from rat striatum in vivo
-
Lamensdorf, I., Youdim, M.B., Finberg, J.P. Effect of long-term treatment with selective monoamine oxidase A and B inhibitors on dopamine release from rat striatum in vivo. J Neurochem 1996, 67: 1532-9.
-
(1996)
J Neurochem
, vol.67
, pp. 1532-1539
-
-
Lamensdorf, I.1
Youdim, M.B.2
Finberg, J.P.3
-
53
-
-
0032498811
-
Increased survival of dopaminergic neurons by rasagiline, a monoamine oxidase B inhibitor
-
Finberg, J.P., Takeshima, T., Johnston, J.M., Commissiong, J.W. Increased survival of dopaminergic neurons by rasagiline, a monoamine oxidase B inhibitor. Neuroreport 1998, 9: 703-7.
-
(1998)
Neuroreport
, vol.9
, pp. 703-707
-
-
Finberg, J.P.1
Takeshima, T.2
Johnston, J.M.3
Commissiong, J.W.4
-
54
-
-
0029832455
-
Effect of long-term treatment with selective monoamine oxidase a and B inhibitors on dopamine release from rat striatum in vivo
-
Lamensdorf, L., Youdim, M.B., Finberg, J.P. Effect of long-term treatment with selective monoamine oxidase A and B inhibitors on dopamine release from rat striatum in vivo. J Neurochem 1996, 67: 1532-9.
-
(1996)
J Neurochem
, vol.67
, pp. 1532-1539
-
-
Lamensdorf, L.1
Youdim, M.B.2
Finberg, J.P.3
-
55
-
-
0032955147
-
Effect of low-dose treatment with selegiline on dopamine transporter (DAT) expression and amphetamine-induced dopamine release in vivo
-
Lamensdorf, I., Porat, S., Simantov, R., Finberg, J.P. Effect of low-dose treatment with selegiline on dopamine transporter (DAT) expression and amphetamine-induced dopamine release in vivo. Br J Pharmacol 1999, 126: 997-1002.
-
(1999)
Br J Pharmacol
, vol.126
, pp. 997-1002
-
-
Lamensdorf, I.1
Porat, S.2
Simantov, R.3
Finberg, J.P.4
-
56
-
-
0015763585
-
Beta-phenylethylamine: A specific substrate for type B monoamine oxidase of brain
-
Yang, H.Y., Neff, N.H. Beta-phenylethylamine: A specific substrate for type B monoamine oxidase of brain. J Pharmacol Exp Ther 1973, 187: 365-71.
-
(1973)
J Pharmacol Exp Ther
, vol.187
, pp. 365-371
-
-
Yang, H.Y.1
Neff, N.H.2
-
57
-
-
0017113881
-
-
Ciba Foundation Symposium, Elsevier, Amsterdam
-
Maitre, L., Delini-Stula, A., Waldmeier, P.C. Relation between the degree of monoamine oxidase inhibition and some psychopharmacological responses to monoamine oxidase inhibitors. Ciba Foundation Symposium, Elsevier, Amsterdam 1976, 39: 247-67.
-
(1976)
Relation between the Degree of Monoamine Oxidase Inhibition and Some Psychopharmacological Responses to Monoamine Oxidase Inhibitors
, vol.39
, pp. 247-267
-
-
Maitre, L.1
Delini-Stula, A.2
Waldmeier, P.C.3
-
58
-
-
0018068628
-
On the mode of action of L-deprenyl in the human central nervous system
-
Riederer, P., Youdim, M.B., Rausch, W.D., Birkmayer, W., Jellinger, K., Seemann, D. On the mode of action of L-deprenyl in the human central nervous system. J Neural Transm 1978, 43: 217-26.
-
(1978)
J Neural Transm
, vol.43
, pp. 217-226
-
-
Riederer, P.1
Youdim, M.B.2
Rausch, W.D.3
Birkmayer, W.4
Jellinger, K.5
Seemann, D.6
-
59
-
-
0016333002
-
The use of selective monoamine oxidase inhibitor drugs to modify amine metabolism in brain
-
Neff, N.H., Yang, H.Y., Fuentes, J.A. The use of selective monoamine oxidase inhibitor drugs to modify amine metabolism in brain. Adv Biochem Psychopharmacol 1974, 12: 49-57.
-
(1974)
Adv Biochem Psychopharmacol
, vol.12
, pp. 49-57
-
-
Neff, N.H.1
Yang, H.Y.2
Fuentes, J.A.3
-
60
-
-
0024418295
-
The novel neuropsychotropic agent milacemide is a specific enzyme-activated inhibitor of brain monoamine oxidase B
-
Janssens de Varebeke, P., Pauwels, G., Buyse, C. et al. The novel neuropsychotropic agent milacemide is a specific enzyme-activated inhibitor of brain monoamine oxidase B. J Neurochem 1989, 53: 1109-16.
-
(1989)
J Neurochem
, vol.53
, pp. 1109-1116
-
-
Janssens De Varebeke, P.1
Pauwels, G.2
Buyse, C.3
-
61
-
-
0027264145
-
Dopamine metabolism and neurotransmission in primate brain in relationship to monoamine oxidase A and B inhibition
-
Youdim, M.B., Riederer, P. Dopamine metabolism and neurotransmission in primate brain in relationship to monoamine oxidase A and B inhibition. J Neural Transm Gen Sect 1993, 91: 181-95.
-
(1993)
J Neural Transm Gen Sect
, vol.91
, pp. 181-195
-
-
Youdim, M.B.1
Riederer, P.2
-
62
-
-
0022378166
-
Prevention of MPTP neurotoxicity by AGN1133 and AGN-1135, selective inhibitors of monoamine oxidase
-
Heikkila, R.E., Duvoisin, R.C., Finberg, J.P., Youdim, M.B.H. Prevention of MPTP neurotoxicity by AGN1133 and AGN-1135, selective inhibitors of monoamine oxidase. B Eur J Pharmacol 1985, 116:3 13-7.
-
(1985)
B Eur J Pharmacol
, vol.116
, pp. 313-317
-
-
Heikkila, R.E.1
Duvoisin, R.C.2
Finberg, J.P.3
Youdim, M.B.H.4
-
63
-
-
0032101092
-
Sparing by rasagiline (TVP-1012) of cholinergic functions and behavior in the postnatal anoxia rat
-
Speiser, Z., Katzir, O., Rehavi, M., Zabarski, T., Cohen, S. Sparing by rasagiline (TVP-1012) of cholinergic functions and behavior in the postnatal anoxia rat. Pharmacol Biochem Behav 1998, 60: 387-93.
-
(1998)
Pharmacol Biochem Behav
, vol.60
, pp. 387-393
-
-
Speiser, Z.1
Katzir, O.2
Rehavi, M.3
Zabarski, T.4
Cohen, S.5
-
64
-
-
0031596710
-
Effects of N-propargyl-1-(R)aminoindan (rasagiline) in models of motor and cognition disorders
-
Speiser, Z., Levy, R., Cohen, S. Effects of N-propargyl-1-(R)aminoindan (rasagiline) in models of motor and cognition disorders. J Neural Transm Suppl 1998, 52: 287-300.
-
(1998)
J Neural Transm Suppl
, vol.52
, pp. 287-300
-
-
Speiser, Z.1
Levy, R.2
Cohen, S.3
-
65
-
-
0032999575
-
Neuroprotective effect of rasagiline, a selective monoamine oxidase-B inhibitor, against closed head injury in the mouse
-
Huang, W., Chen, Y., Shohami, E., Weinstock, M. Neuroprotective effect of rasagiline, a selective monoamine oxidase-B inhibitor, against closed head injury in the mouse. Eur J Pharmacol 1999, 366: 127-35.
-
(1999)
Eur J Pharmacol
, vol.366
, pp. 127-135
-
-
Huang, W.1
Chen, Y.2
Shohami, E.3
Weinstock, M.4
-
66
-
-
4644225112
-
Rasagiline alone and in combination with riluzole prolongs survival in an ALS mouse model
-
Waibel, S., Reuter, A., Malessa, S., Blaugrund, E., Ludolph, A.C. Rasagiline alone and in combination with riluzole prolongs survival in an ALS mouse model. J Neurol 2004, 251: 1080-4.
-
(2004)
J Neurol
, vol.251
, pp. 1080-1084
-
-
Waibel, S.1
Reuter, A.2
Malessa, S.3
Blaugrund, E.4
Ludolph, A.C.5
-
67
-
-
2342547676
-
Neuroprotective effect of rasagiline in a rodent model of Parkinson's disease
-
Blandini, F., Armentero, M.T., Fancellu, R., Blaugrund, E., Nappi, G. Neuroprotective effect of rasagiline in a rodent model of Parkinson's disease. Exp Neurol 2004, 187: 455-9.
-
(2004)
Exp Neurol
, vol.187
, pp. 455-459
-
-
Blandini, F.1
Armentero, M.T.2
Fancellu, R.3
Blaugrund, E.4
Nappi, G.5
-
68
-
-
0037461309
-
Neuroprotective agents for clinical trials in Parkinson's disease: A systematic assessment
-
Ravina, B.M., Fagan, S.C., Hart, R.G. et al. Neuroprotective agents for clinical trials in Parkinson's disease: A systematic assessment. Neurology 2003, 22, 60: 1234-40.
-
(2003)
Neurology
, vol.22-60
, pp. 1234-1240
-
-
Ravina, B.M.1
Fagan, S.C.2
Hart, R.G.3
-
69
-
-
0032726944
-
Neuroprotection by (-)-deprenyl and related compounds
-
Maruyama, W., Naoi, M. Neuroprotection by (-)-deprenyl and related compounds. Mech Ageing Dev 1999, 111: 189-200.
-
(1999)
Mech Ageing Dev
, vol.111
, pp. 189-200
-
-
Maruyama, W.1
Naoi, M.2
-
70
-
-
0034939146
-
Anti-apoptotic function of N-propargylamine-1(R)-and (S)-aminoindan, Rasagiline and TV1022
-
Maruyama, W., Youdim, M.B.H., Naoi, M. Anti-apoptotic function of N-propargylamine-1(R)-and (S)-aminoindan, Rasagiline and TV1022. Ann NY Acad Sci 2000, 939: 320-9.
-
(2000)
Ann NY Acad Sci
, vol.939
, pp. 320-329
-
-
Maruyama, W.1
Youdim, M.B.H.2
Naoi, M.3
-
71
-
-
0034525891
-
Neurotoxins induce apoptosis in dopamine neurons: Protection by N-propargylamine 1(R)-and (S)-aminoindan, rasagiline and TV1022
-
Maruyama, W., Akao, Y., Youdim, M.B.H., Naoi, M. Neurotoxins induce apoptosis in dopamine neurons: Protection by N-propargylamine 1(R)-and (S)-aminoindan, rasagiline and TV1022. J Neural Transm 2000, 60: 171-86.
-
(2000)
J Neural Transm
, vol.60
, pp. 171-186
-
-
Maruyama, W.1
Akao, Y.2
Youdim, M.B.H.3
Naoi, M.4
-
72
-
-
0034928655
-
Enantio-specific induction of apoptosis by an endogenous neurotoxin, N-methyl(R)salsolinol, in dopaminergic SH-SY5Y cells: Suppression of apoptosis by N-(2-heptyl)-N-methylpropargylamine
-
Maruyama, W., Boulton, A. A., Davis, B.A., Dostert, P., Naoi, M. Enantio-specific induction of apoptosis by an endogenous neurotoxin, N-methyl(R)salsolinol, in dopaminergic SH-SY5Y cells: Suppression of apoptosis by N-(2-heptyl)-N-methylpropargylamine. J Neural Transm 2001, 108: 11-24.
-
(2001)
J Neural Transm
, vol.108
, pp. 11-24
-
-
Maruyama, W.1
Boulton, A.A.2
Davis, B.A.3
Dostert, P.4
Naoi, M.5
-
73
-
-
0034884148
-
Transfection-enforced Bcl-2 overexpression and an anti-Parkinson drug, rasagiline, prevent nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase induced by an endogenous dopaminergicneurotoxin, N-methyl(R)salsolinol
-
Maruyama, W., Akao, Y., Youdim, M.B., Davis, B.A., Naoi, M. Transfection-enforced Bcl-2 overexpression and an anti-Parkinson drug, rasagiline, prevent nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase induced by an endogenous dopaminergicneurotoxin, N-methyl(R)salsolinol. J Neurochem 2001, 78: 727-35.
-
(2001)
J Neurochem
, vol.78
, pp. 727-735
-
-
Maruyama, W.1
Akao, Y.2
Youdim, M.B.3
Davis, B.A.4
Naoi, M.5
-
74
-
-
0036719861
-
Neuroprotection by propargylamines in Parkinson's disease: Suppression of apoptosis and induction of prosurvival genes
-
Maruyama, W., Akao, Y., Carrillo, M.C., Kitani, K., Youdium, M.B., Naoi, M. Neuroprotection by propargylamines in Parkinson's disease: Suppression of apoptosis and induction of prosurvival genes. Neurotoxicol Teratol 2002, 24: 675-82.
-
(2002)
Neurotoxicol Teratol
, vol.24
, pp. 675-682
-
-
Maruyama, W.1
Akao, Y.2
Carrillo, M.C.3
Kitani, K.4
Youdium, M.B.5
Naoi, M.6
-
75
-
-
0036206323
-
The anti-Parkinson drug, rasagiline, prevents apoptotic DNA damage induced by peroxynitrite in human dopaminergic neuroblastoma SH-SY5Y cells
-
Maruyama, W., Takahashi, T., Youdim, M., Naoi, M. The anti-Parkinson drug, rasagiline, prevents apoptotic DNA damage induced by peroxynitrite in human dopaminergic neuroblastoma SH-SY5Y cells. J Neural Transm 2002, 109:467-81.
-
(2002)
J Neural Transm
, vol.109
, pp. 467-481
-
-
Maruyama, W.1
Takahashi, T.2
Youdim, M.3
Naoi, M.4
-
76
-
-
0035568344
-
Molecular basis of neuroprotective activities of rasagiline and the anti-Alzheimer drug, TV3326, [(N-propargyl-(3R)aminoindan-5-yl)-ethyl methyl carbamate]
-
Youdim, M.B.H., Weinstock, M. Molecular basis of neuroprotective activities of rasagiline and the anti-Alzheimer drug, TV3326, [(N-propargyl-(3R)aminoindan-5-yl)-ethyl methyl carbamate]. Cell Mol Neurobiol 2002, 21: 555-73.
-
(2002)
Cell Mol Neurobiol
, vol.21
, pp. 555-573
-
-
Youdim, M.B.H.1
Weinstock, M.2
-
77
-
-
0033756901
-
Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease
-
Tatton, N.A. Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease. Exp Neurol 2000, 166: 29-43.
-
(2000)
Exp Neurol
, vol.166
, pp. 29-43
-
-
Tatton, N.A.1
-
78
-
-
0036229947
-
Propargylamines induce anti-apoptotic new protein synthesis in serum- and nerve growth factor (NGF)-withdrawn, NGF-differentiated PC-12 cells
-
Tatton, W.G., Chalmers-Redman, R.M., Ju, W.J. et al. Propargylamines induce anti-apoptotic new protein synthesis in serum- and nerve growth factor (NGF)-withdrawn, NGF-differentiated PC-12 cells. J Pharmacol Exp Therap 2002, 301, 753-64.
-
(2002)
J Pharmacol Exp Therap
, vol.301
, pp. 753-764
-
-
Tatton, W.G.1
Chalmers-Redman, R.M.2
Ju, W.J.3
-
79
-
-
0345237921
-
Anti-apoptotic action of anti-Alzheimer drug, TV3326 [(N-propargyl)-(3R)- aminoindan-5-yl]-ethyl methyl carbamate, a novel cholinesterase-monoamine oxidase inhibitor
-
Maruyama, W., Weinstock, M., Youdim, M.B., Nagai, M., Naoi, M. Anti-apoptotic action of anti-Alzheimer drug, TV3326 [(N-propargyl)-(3R)- aminoindan-5-yl]-ethyl methyl carbamate, a novel cholinesterase-monoamine oxidase inhibitor. Neurosci Lett 2003, 341: 233-6.
-
(2003)
Neurosci Lett
, vol.341
, pp. 233-236
-
-
Maruyama, W.1
Weinstock, M.2
Youdim, M.B.3
Nagai, M.4
Naoi, M.5
-
80
-
-
0036719861
-
Neuroprotection by propargylamines in Parkinson's disease: Suppression of apoptosis and induction of prosurvival genes
-
Maruyama, W., Akao, Y., Carrillo, M.C., Kitani, K., Youdium, M.B., Naoi, M. Neuroprotection by propargylamines in Parkinson's disease: Suppression of apoptosis and induction of prosurvival genes. Neurotoxicol Teratol 2002, 24: 675-82.
-
(2002)
Neurotoxicol Teratol
, vol.24
, pp. 675-682
-
-
Maruyama, W.1
Akao, Y.2
Carrillo, M.C.3
Kitani, K.4
Youdium, M.B.5
Naoi, M.6
-
81
-
-
0027530638
-
Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease
-
Parkinson Study Group. Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease. N Engl J Med 1993, 328: 176-83.
-
(1993)
N Engl J Med
, vol.328
, pp. 176-183
-
-
-
82
-
-
0033231244
-
Rosagiline, a monoamine oxidase-B inhibitor, protects NGF-differentiated PC12 cells against oxygen-glucose deprivation
-
Abu-Raya, S., Blaugrund, E., Trembovler, V., Shilderman-Bloch, E., Shohami, E., Lazarovici, P. Rosagiline, a monoamine oxidase-B inhibitor, protects NGF-differentiated PC12 cells against oxygen-glucose deprivation. J Neurosci Res 1999, 58: 456-63.
-
(1999)
J Neurosci Res
, vol.58
, pp. 456-463
-
-
Abu-Raya, S.1
Blaugrund, E.2
Trembovler, V.3
Shilderman-Bloch, E.4
Shohami, E.5
Lazarovici, P.6
-
83
-
-
0037059430
-
Neuroprotective and neurotoxic effects of monoamine oxidase-B inhibitors and derived metabolites under ischemia in PC12 cells
-
Abu-Raya, S., Tabakman, R., Blaugrund, E., Trembovler, V., Lazarovici, P. Neuroprotective and neurotoxic effects of monoamine oxidase-B inhibitors and derived metabolites under ischemia in PC12 cells. Eur J Pharmacol 2002, 434: 109-16P.
-
(2002)
Eur J Pharmacol
, vol.434
-
-
Abu-Raya, S.1
Tabakman, R.2
Blaugrund, E.3
Trembovler, V.4
Lazarovici, P.5
-
84
-
-
1542317394
-
Contrasting neuroprotective and neurotoxic actions of respective metabolites of antiparkinson drugs rasagiline and selegiline
-
in press
-
Bar Am, O., Amit, T., Youdim, M.B.H. Contrasting neuroprotective and neurotoxic actions of respective metabolites of antiparkinson drugs rasagiline and selegiline. Neurosci Lett 2004, in press.
-
(2004)
Neurosci Lett
-
-
Bar Am, O.1
Amit, T.2
Youdim, M.B.H.3
-
85
-
-
0032807402
-
Studies with rasagiline, a MAO-B inhibitor, in experimental focal ischemia in the rat
-
Speiser, Z., Mayk, A., Eliash, S., Cohen, S. Studies with rasagiline, a MAO-B inhibitor, in experimental focal ischemia in the rat. J Neural Transm 1999, 106: 59.
-
(1999)
J Neural Transm
, vol.106
, pp. 59
-
-
Speiser, Z.1
Mayk, A.2
Eliash, S.3
Cohen, S.4
-
86
-
-
0028181797
-
(-)-Deprenyl alters the survival of adult murine facial motoneurons after axotomy: Increases in vulnerable C57BL strain but decreases in motor neuron degeneration mutants
-
Oh, C., Murray, B., Bhattacharya, N., Holland, D., Tatton, W.G. (-)-Deprenyl alters the survival of adult murine facial motoneurons after axotomy: Increases in vulnerable C57BL strain but decreases in motor neuron degeneration mutants. J Neurosci Res 1994, 38: 64-74.
-
(1994)
J Neurosci Res
, vol.38
, pp. 64-74
-
-
Oh, C.1
Murray, B.2
Bhattacharya, N.3
Holland, D.4
Tatton, W.G.5
-
87
-
-
0037198060
-
Novel neuroprotective anti-Alzheimer drugs with anti-depressant activity derived from the anti-Parkinson drug, rasagiline
-
Youdim, M.B., Weinstock, M. Novel neuroprotective anti-Alzheimer drugs with anti-depressant activity derived from the anti-Parkinson drug, rasagiline. Mech Ageing Dev 2002, 123: 1081-6.
-
(2002)
Mech Ageing Dev
, vol.123
, pp. 1081-1086
-
-
Youdim, M.B.1
Weinstock, M.2
-
88
-
-
0034705512
-
Enhancing effect of rasagiline on superoxide dismutase and catalase activities in the dopaminergic system in the rat
-
Carrillo, M.C., Minami, C., Kitani, K. et al. Enhancing effect of rasagiline on superoxide dismutase and catalase activities in the dopaminergic system in the rat. Life Sci 2000, 67: 577-85.
-
(2000)
Life Sci
, vol.67
, pp. 577-585
-
-
Carrillo, M.C.1
Minami, C.2
Kitani, K.3
-
89
-
-
0023029305
-
Contrasting monoamine oxidase activity and tyramine induced catecholamine release in PC12 and chromaffin cells
-
Youdim, M.B., Heldman, E., Pollard, H.B., Fleming, P., McHugh, E. Contrasting monoamine oxidase activity and tyramine induced catecholamine release in PC12 and chromaffin cells. Neuroscience 1986, 19: 1311-8.
-
(1986)
Neuroscience
, vol.19
, pp. 1311-1318
-
-
Youdim, M.B.1
Heldman, E.2
Pollard, H.B.3
Fleming, P.4
McHugh, E.5
-
90
-
-
0036329996
-
Mitochondria determine the survival and death in apoptosis by an endogenous neurotoxin, N-methyl(R)salsolinol, and neuroprotection by propargylamines
-
Naoi, M., Maruyama, W., Akao, Y., Yi, H. Mitochondria determine the survival and death in apoptosis by an endogenous neurotoxin, N-methyl(R)salsolinol, and neuroprotection by propargylamines. J Neural Transm 2002, 109: 607-21.
-
(2002)
J Neural Transm
, vol.109
, pp. 607-621
-
-
Naoi, M.1
Maruyama, W.2
Akao, Y.3
Yi, H.4
-
91
-
-
0037321610
-
Attenuation of methamphetamine induced dopaminergic neurotoxicity by flupirtine: Microdialysis study on dopamine release and free radical generation
-
Gassen, M., Lamensdorf, I., Armony, T., Finberg, J.P., Youdim, M.B. Attenuation of methamphetamine induced dopaminergic neurotoxicity by flupirtine: Microdialysis study on dopamine release and free radical generation. J Neural Transm 2003, 110: 171-82.
-
(2003)
J Neural Transm
, vol.110
, pp. 171-182
-
-
Gassen, M.1
Lamensdorf, I.2
Armony, T.3
Finberg, J.P.4
Youdim, M.B.5
-
92
-
-
0032885411
-
Protection with metabotropic glutamate 1 receptor antagonists in models of ischemic neuronal death: Time-course and mechanisms
-
Pellegrini-Giampietro, D.E., Peruginelli, F., Meli, E. et al. Protection with metabotropic glutamate 1 receptor antagonists in models of ischemic neuronal death: Time-course and mechanisms. Neuropharmacology 1999, 38: 1607-19.
-
(1999)
Neuropharmacology
, vol.38
, pp. 1607-1619
-
-
Pellegrini-Giampietro, D.E.1
Peruginelli, F.2
Meli, E.3
-
93
-
-
23144451035
-
Genomic and proteomic profiling of the neuroprotective mechanism of rasagiline in the mouse model of PD
-
Sagi, Y., Mandel, S., Youdim, M.B.H. Genomic and proteomic profiling of the neuroprotective mechanism of rasagiline in the mouse model of PD. Neural Plsticity 2003, 10: 227.
-
(2003)
Neural Plsticity
, vol.10
, pp. 227
-
-
Sagi, Y.1
Mandel, S.2
Youdim, M.B.H.3
-
94
-
-
0141649550
-
The adenine nucleotide translocator: A new potential chemotherapeutic target
-
review
-
Belzacq, A.S., Brenner, C. The adenine nucleotide translocator: A new potential chemotherapeutic target. Curr Drug Targets 2003, 7: 517-24, review.
-
(2003)
Curr Drug Targets
, vol.7
, pp. 517-524
-
-
Belzacq, A.S.1
Brenner, C.2
-
95
-
-
0036478993
-
The adenine nucleotide translocator in apoptosis
-
Belzacq, A.S., Vieira, H.L., Kroemer, G., Brenner, C. The adenine nucleotide translocator in apoptosis. Biochimie 2002, 84: 167-76.
-
(2002)
Biochimie
, vol.84
, pp. 167-176
-
-
Belzacq, A.S.1
Vieira, H.L.2
Kroemer, G.3
Brenner, C.4
-
96
-
-
0036478993
-
The adenine nucleotide translocator in apoptosis
-
Belzacq, A.S., Vieira, H.L., Kroemer, G., Brenner, C. The adenine nucleotide translocator in apoptosis. Biochimie 2002, 84: 167-76.
-
(2002)
Biochimie
, vol.84
, pp. 167-176
-
-
Belzacq, A.S.1
Vieira, H.L.2
Kroemer, G.3
Brenner, C.4
-
97
-
-
0036478989
-
The permeability transition pore complex: Another view
-
Halestrap, A.P., McStay, G.P., Clarke, S.J. The permeability transition pore complex: Another view. Biochimie 2002, 84: 153-66.
-
(2002)
Biochimie
, vol.84
, pp. 153-166
-
-
Halestrap, A.P.1
McStay, G.P.2
Clarke, S.J.3
-
98
-
-
0035059412
-
Mitochondria: A target for myocardial protection
-
Suleiman, M.S., Halestrap, A.P., Griffiths, E.J. Mitochondria: A target for myocardial protection. Pharmacol Ther 2001, 89: 29-46.
-
(2001)
Pharmacol Ther
, vol.89
, pp. 29-46
-
-
Suleiman, M.S.1
Halestrap, A.P.2
Griffiths, E.J.3
-
99
-
-
0036677312
-
Mitochondrial permeability transition mediates apoptosis induced by N-methyl(R)salsolinol, an endogenous neurotoxin, and is inhibited by Bc1-2 and rasagiline, N-propargyl-1 (R)-aminoindan
-
Akao, Y., Maruyama, W., Shimizu, S. et al. Mitochondrial permeability transition mediates apoptosis induced by N-methyl(R)salsolinol, an endogenous neurotoxin, and is inhibited by Bc1-2 and rasagiline, N-propargyl-1 (R)-aminoindan. J Neurochem 2002, 82: 913-23.
-
(2002)
J Neurochem
, vol.82
, pp. 913-923
-
-
Akao, Y.1
Maruyama, W.2
Shimizu, S.3
-
100
-
-
0038322479
-
cDNA gene expression profile homology of antioxidants and their antiapoptotic and proapoptotic activities in human neuroblastoma cells
-
Weinreb, O., Mandel, S., Youdim, M.B. cDNA gene expression profile homology of antioxidants and their antiapoptotic and proapoptotic activities in human neuroblastoma cells. FASEB J 2003, 17: 935-7.
-
(2003)
FASEB J
, vol.17
, pp. 935-937
-
-
Weinreb, O.1
Mandel, S.2
Youdim, M.B.3
-
101
-
-
0642303109
-
The importance of propargylamine moiety in the anti-Parkinson drug rasagiline and its derivatives in MAPK-dependent amyloid precursor protein processing
-
Yogev-Falach, M., Amit, T., Bar-Am, O., Youdim M.B. The importance of propargylamine moiety in the anti-Parkinson drug rasagiline and its derivatives in MAPK-dependent amyloid precursor protein processing. FASEB J 2003, 17: 2325-7.
-
(2003)
FASEB J
, vol.17
, pp. 2325-2327
-
-
Yogev-Falach, M.1
Amit, T.2
Bar-Am, O.3
Youdim, M.B.4
-
102
-
-
33544467024
-
The neuroprotective activity of rasagiline and its propargyl moiety is dependent on activation/gene expression of protein kinase C (PKC)
-
Bar Am, O., Amit, T., Weinreb, O., Yogev-Falach, M., Youdim, M.B.H. The neuroprotective activity of rasagiline and its propargyl moiety is dependent on activation/gene expression of protein kinase C (PKC). Neural Plasticity 2003, 10: 183.
-
(2003)
Neural Plasticity
, vol.10
, pp. 183
-
-
Bar Am, O.1
Amit, T.2
Weinreb, O.3
Yogev-Falach, M.4
Youdim, M.B.H.5
-
103
-
-
33544467409
-
Gene and protein expression profiles of neuroprotective and anti-apoptotic action of rasagiline in PC-12 cell cultures
-
Weinreb, O., Bar Am, O., Chilag-Tamar, O., Amit, T., Youdim, M.B.H. Gene and protein expression profiles of neuroprotective and anti-apoptotic action of rasagiline in PC-12 cell cultures. Neural Plasticity 2003, 10: 238.
-
(2003)
Neural Plasticity
, vol.10
, pp. 238
-
-
Weinreb, O.1
Bar Am, O.2
Chilag-Tamar, O.3
Amit, T.4
Youdim, M.B.H.5
-
104
-
-
0035062462
-
Immunophilin ligands can prevent progressive e dopaminergic degeneration in animal models of Parkinson's disease
-
Constantini, L.C., Cole, D., Chatuvedi, P., Isacson, P. Immunophilin ligands can prevent progressive e dopaminergic degeneration in animal models of Parkinson's disease. J Eur Neurosci 2001, 13: 1085-92.
-
(2001)
J Eur Neurosci
, vol.13
, pp. 1085-1092
-
-
Constantini, L.C.1
Cole, D.2
Chatuvedi, P.3
Isacson, P.4
-
105
-
-
0037189081
-
An anti-Parkinson's disease drug, N-propargyl-1(R)-aminoindan (rasagiline), enhances expression of anti-apoptotic bcl-2 in human dopaminergic SH-SY5Y cells
-
Akao, Y., Maruyama, W., Yi, H., Shamoto-Nagai, M., Youdim, M.B., Naoi, M. An anti-Parkinson's disease drug, N-propargyl-1(R)-aminoindan (rasagiline), enhances expression of anti-apoptotic bcl-2 in human dopaminergic SH-SY5Y cells. Neurosci Lett 2002, 326: 105-8.
-
(2002)
Neurosci Lett
, vol.326
, pp. 105-108
-
-
Akao, Y.1
Maruyama, W.2
Yi, H.3
Shamoto-Nagai, M.4
Youdim, M.B.5
Naoi, M.6
-
106
-
-
0038155162
-
Attenuation of MPTP-induced dopaminergic neurotoxicity by TV3326, a cholinesterase-monoamine oxidase inhibitor
-
Sagi, Y., Weinstock, M., Youdim, M.B.H. Attenuation of MPTP-Induced Dopaminergic Neurotoxicity by TV3326, A cholinesterase-monoamine oxidase inhibitor. J Neurochem 2003, 2: 290-7.
-
(2003)
J Neurochem
, vol.2
, pp. 290-297
-
-
Sagi, Y.1
Weinstock, M.2
Youdim, M.B.H.3
-
107
-
-
0023764824
-
The molecular heterogeneity of protein kinase C and its implications for cellular regulation
-
Nishizuka, Y. The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 1998, 334: 661-5.
-
(1998)
Nature
, vol.334
, pp. 661-665
-
-
Nishizuka, Y.1
-
108
-
-
0022154427
-
Tumor-promoting phorbol diester mimics two distinct neuronotrophic factors
-
Montz, H.P., Davis, G.E., Skaper, S.D., Manthorpe, M., Varon, S. Tumor-promoting phorbol diester mimics two distinct neuronotrophic factors. Brain Res 1985, 355: 150-4.
-
(1985)
Brain Res
, vol.355
, pp. 150-154
-
-
Montz, H.P.1
Davis, G.E.2
Skaper, S.D.3
Manthorpe, M.4
Varon, S.5
-
109
-
-
0022553361
-
Protein kinase Casa component of a nerve growth factor-sensitive phosphorylation system in PC12 cells
-
Hama, T., Huang, K.P., Guroff, G. Protein kinase Casa component of a nerve growth factor-sensitive phosphorylation system in PC12 cells. Proc Natl Acad Sci USA 1986, 83: 2353-7.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 2353-2357
-
-
Hama, T.1
Huang, K.P.2
Guroff, G.3
-
110
-
-
0034041345
-
Pharmacological demonstration of the differential involvement of protein kinase C isoforms in short- and long-term memory formation and retrieval of one-trial avoidance in rats
-
Vianna, M.R., Barros, D.M., Silva, T. et al. Pharmacological demonstration of the differential involvement of protein kinase C isoforms in short- and long-term memory formation and retrieval of one-trial avoidance in rats. Psychopharmacology (Berl) 2000, 150: 77-84.
-
(2000)
Psychopharmacology (Berl)
, vol.150
, pp. 77-84
-
-
Vianna, M.R.1
Barros, D.M.2
Silva, T.3
-
111
-
-
0029240533
-
Changes in protein kinases in brain aging and Alzheimer's disease. Implications for drug therapy
-
Jin, L.W., Saitoh, T. Changes in protein kinases in brain aging and Alzheimer's disease. Implications for drug therapy. Drugs Aging 1995, 6: 136-49.
-
(1995)
Drugs Aging
, vol.6
, pp. 136-149
-
-
Jin, L.W.1
Saitoh, T.2
-
112
-
-
0025833830
-
Protein kinase C alteration is an early biochemical marker in Alzheimer's disease
-
Masliah, E., Cole, G.M., Hansen, L.A. et al. Protein kinase C alteration is an early biochemical marker in Alzheimer's disease. J Neurosci 1991, 11: 2759-67.
-
(1991)
J Neurosci
, vol.11
, pp. 2759-2767
-
-
Masliah, E.1
Cole, G.M.2
Hansen, L.A.3
-
113
-
-
0027265320
-
Assessment of protein kinase C isozymes by two-site enzyme immunoassay in human brains and changes in Alzheimer's disease
-
Shimohama, S., Narita, M., Matsushima, H., Kimura, J., Kameyama, M., Hagiwara M., Hidaka, H., Taniguchi, T. Assessment of protein kinase C isozymes by two-site enzyme immunoassay in human brains and changes in Alzheimer's disease. Neurology 1993, 43: 1407-13.
-
(1993)
Neurology
, vol.43
, pp. 1407-1413
-
-
Shimohama, S.1
Narita, M.2
Matsushima, H.3
Kimura, J.4
Kameyama, M.5
Hagiwara, M.6
Hidaka, H.7
Taniguchi, T.8
-
115
-
-
0028916836
-
Membrane alterations as causes of impaired signal transduction in Alzheimer's disease and aging
-
Roth, G.S., Joseph, J.A., Mason, R.P. Membrane alterations as causes of impaired signal transduction in Alzheimer's disease and aging. Trends Neurosci 1995, 18: 203-6.
-
(1995)
Trends Neurosci
, vol.18
, pp. 203-206
-
-
Roth, G.S.1
Joseph, J.A.2
Mason, R.P.3
-
116
-
-
0028339544
-
Attenuated protein kinase C activity and translocation in Alzheimer's disease brain
-
Wang, H.Y., Pisano, M.R., Friedman, E. Attenuated protein kinase C activity and translocation in Alzheimer's disease brain. Neurobiol Aging 1994, 15: 293-8.
-
(1994)
Neurobiol Aging
, vol.15
, pp. 293-298
-
-
Wang, H.Y.1
Pisano, M.R.2
Friedman, E.3
-
117
-
-
0025296205
-
Processing of Alzheimer beta/A4 amyloid precursor protein: Modulation by agents that regulate protein phosphorylation
-
Buxbaum, J.D., Gandy, S.E., Cicchetti, P. et al. Processing of Alzheimer beta/A4 amyloid precursor protein: Modulation by agents that regulate protein phosphorylation. Proc Natl Acad Sci USA 1990, 87: 6003-6.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6003-6006
-
-
Buxbaum, J.D.1
Gandy, S.E.2
Cicchetti, P.3
-
118
-
-
0026476297
-
Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors
-
Nitsch, R.M., Slack, B.E., Wurtman, R.J., Growdon, J.H. Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. Science 1992, 258: 304-7.
-
(1992)
Science
, vol.258
, pp. 304-307
-
-
Nitsch, R.M.1
Slack, B.E.2
Wurtman, R.J.3
Growdon, J.H.4
-
119
-
-
0027487188
-
Regulation by phorbol esters of amyloid precursor protein release from Swiss 3T3 fibroblasts overexpressing protein kinase C alpha
-
Slack, B.E., Nitsch, R.M., Livneh, E. et al. Regulation by phorbol esters of amyloid precursor protein release from Swiss 3T3 fibroblasts overexpressing protein kinase C alpha. J Biol Chem 1993, 268: 21097-101.
-
(1993)
J Biol Chem
, vol.268
, pp. 21097-21101
-
-
Slack, B.E.1
Nitsch, R.M.2
Livneh, E.3
-
120
-
-
0029379605
-
Processing of the beta-amyloid precursor protein and its regulation in Alzheimer's disease
-
Checler, F. Processing of the beta-amyloid precursor protein and its regulation in Alzheimer's disease. J Neurochem 1995, 65: 1431-44.
-
(1995)
J Neurochem
, vol.65
, pp. 1431-1444
-
-
Checler, F.1
-
121
-
-
0030921730
-
Increased secretion of the amino-terminal fragment of amyloid precursor protein in brains of rats with a constitutive up-regulation of protein kinase C
-
Caputi, A., Barindelli, S., Pastorino, L. et al. Increased secretion of the amino-terminal fragment of amyloid precursor protein in brains of rats with a constitutive up-regulation of protein kinase C. J Neurochem 1997, 68: 2523-9.
-
(1997)
J Neurochem
, vol.68
, pp. 2523-2529
-
-
Caputi, A.1
Barindelli, S.2
Pastorino, L.3
-
122
-
-
0030722499
-
In vivo regulation of amyloid precursor protein secretion in rat neocortex by cholinergic activity
-
Rossner, S., Ueberham, U., Yu, J. et al. In vivo regulation of amyloid precursor protein secretion in rat neocortex by cholinergic activity. Eur J Neurosci 1997, 9: 2125-34.
-
(1997)
Eur J Neurosci
, vol.9
, pp. 2125-2134
-
-
Rossner, S.1
Ueberham, U.2
Yu, J.3
-
123
-
-
0032693398
-
Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation
-
Lin, L., Georgievska, B., Mattsson, A., Isacson, O. Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation. Proc Natl Acad Sci USA 1999, 96: 12108-13.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12108-12113
-
-
Lin, L.1
Georgievska, B.2
Mattsson, A.3
Isacson, O.4
-
124
-
-
0036777108
-
The involvement of mitogen-activated protein (MAP) kinase in the regulation of amyloid precursor protein processing by novel cholinesterase inhibitors derived from rasagiline
-
Yogev-Falach, M., Amit, T., Bar-Am, O., Weinstock, M., Youdim, M.B.H. The involvement of mitogen-activated protein (MAP) kinase in the regulation of amyloid precursor protein processing by novel cholinesterase inhibitors derived from rasagiline. FASEB J 2002, 16: 1674-6.
-
(2002)
FASEB J
, vol.16
, pp. 1674-1676
-
-
Yogev-Falach, M.1
Amit, T.2
Bar-Am, O.3
Weinstock, M.4
Youdim, M.B.H.5
-
125
-
-
2642529309
-
Regulation of protein kinase C by the anti-Parkinson drug, MAO-B inhibitor, rasagiline and its derivatives, in vivo
-
Bar Am, O., Yogev-Falach, M., Amit, T., Sagi, Y., Youdim, M.B. Regulation of protein kinase C by the anti-Parkinson drug, MAO-B inhibitor, rasagiline and its derivatives, in vivo. J Neurochem 2004b, 89: 1119-25.
-
(2004)
J Neurochem
, vol.89
, pp. 1119-1125
-
-
Bar Am, O.1
Yogev-Falach, M.2
Amit, T.3
Sagi, Y.4
Youdim, M.B.5
-
126
-
-
0032566717
-
A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis
-
Ruvolo, P.P., Deng, X., Carr, B.K., May, W.S. A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis. J Biol Chem 1998, 273: 25436-42.
-
(1998)
J Biol Chem
, vol.273
, pp. 25436-25442
-
-
Ruvolo, P.P.1
Deng, X.2
Carr, B.K.3
May, W.S.4
-
127
-
-
0035380994
-
Bcl-2 over-expression and activation of protein kinase C suppress the trail-induced apoptosis in Jurkat T cells
-
Quo, B.C., Xu, Y.H. Bcl-2 over-expression and activation of protein kinase C suppress the trail-induced apoptosis in Jurkat T cells. Cell Res 2001, 11: 101-6.
-
(2001)
Cell Res
, vol.11
, pp. 101-106
-
-
Quo, B.C.1
Xu, Y.H.2
-
128
-
-
6944242126
-
Neuroprotection via pro-survival protein kinase C isoforms associated with Bcl-2 family members
-
Weinreb, O., Bar-Am, O., Amit, T., Chillag-Talmor, O., Youdim, M.B. Neuroprotection via pro-survival protein kinase C isoforms associated with Bcl-2 family members. FASEB J 2004, 18: 1471-3.
-
(2004)
FASEB J
, vol.18
, pp. 1471-1473
-
-
Weinreb, O.1
Bar-Am, O.2
Amit, T.3
Chillag-Talmor, O.4
Youdim, M.B.5
-
129
-
-
0027444597
-
AVP-induced activation of MAP kinase in vascular smooth muscle cells is mediated through protein kinase C
-
Kribben, A., Wieder, E.D., Li, X. et al. AVP-induced activation of MAP kinase in vascular smooth muscle cells is mediated through protein kinase C. Am J Physiol 1993, 265: C939-45.
-
(1993)
Am J Physiol
, vol.265
-
-
Kribben, A.1
Wieder, E.D.2
Li, X.3
-
130
-
-
0035341268
-
How protein kinase C activation protects nerve cells from oxidative stress-induced cell death
-
Maher, P. How protein kinase C activation protects nerve cells from oxidative stress-induced cell death. J Neurosci 2001, 21: 2929-38.
-
(2001)
J Neurosci
, vol.21
, pp. 2929-2938
-
-
Maher, P.1
-
131
-
-
0033971901
-
Bcl-2 family: Life-or-death switch
-
Tsujimoto, Y., Shimizu, S. Bcl-2 family: life-or-death switch. FEBS Lett 2000, 466: 6-10.
-
(2000)
FEBS Lett
, vol.466
, pp. 6-10
-
-
Tsujimoto, Y.1
Shimizu, S.2
-
132
-
-
0026472164
-
The MARCKS brothers: A family of protein kinase C substrates
-
Aderem, A. The MARCKS brothers: A family of protein kinase C substrates. Cell 1992, 71: 713-6.
-
(1992)
Cell
, vol.71
, pp. 713-716
-
-
Aderem, A.1
-
133
-
-
0027171638
-
Protein kinase C phosphorylates Ser152, Ser156 and Ser163 but not Ser160 of MARCKS in rat brain
-
Heemskerk, F.M., Chen, H.C., Huang F.L. Protein kinase C phosphorylates Ser152, Ser156 and Ser163 but not Ser160 of MARCKS in rat brain. Biochem Biophys Res Commun 1993, 190: 236-41.
-
(1993)
Biochem Biophys Res Commun
, vol.190
, pp. 236-241
-
-
Heemskerk, F.M.1
Chen, H.C.2
Huang, F.L.3
-
134
-
-
0027392102
-
The MARCKS family of cellular protein kinase C substrates
-
Blackshear, P.J. The MARCKS family of cellular protein kinase C substrates. J Biol Chem 1993, 268: 1501-4.
-
(1993)
J Biol Chem
, vol.268
, pp. 1501-1504
-
-
Blackshear, P.J.1
-
135
-
-
0032479804
-
Distribution of the protein kinase C substrates MARCKS and MRP in the postnatal developing rat brain
-
McNamara, R.K., Lenox, R.H. Distribution of the protein kinase C substrates MARCKS and MRP in the postnatal developing rat brain. J Neurol 1998, 397: 337-56.
-
(1998)
J Neurol
, vol.397
, pp. 337-356
-
-
McNamara, R.K.1
Lenox, R.H.2
-
136
-
-
0032564337
-
Effect of reduced myristoylated alanine-rich C kinase substrate expression on hippocampal mossy fiber development and spatial learning in mutant mice: Transgenic rescue and interactions with gene background
-
McNamara, R.K., Stumpo, D.J., Morel, L.M. et al. Effect of reduced myristoylated alanine-rich C kinase substrate expression on hippocampal mossy fiber development and spatial learning in mutant mice: Transgenic rescue and interactions with gene background. Proc Natl Acad Sci USA 1998, 95: 14517-22.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14517-14522
-
-
McNamara, R.K.1
Stumpo, D.J.2
Morel, L.M.3
-
137
-
-
0027379653
-
Hyperactivation of signal transduction systems in Alzheimer's disease
-
Saitoh, T., Horsburgh, K., Masliah, E. Hyperactivation of signal transduction systems in Alzheimer's disease. Ann NY Acad Sci 1993, 695: 34-41.
-
(1993)
Ann NY Acad Sci
, vol.695
, pp. 34-41
-
-
Saitoh, T.1
Horsburgh, K.2
Masliah, E.3
-
138
-
-
0028938152
-
Localization of protein kinases by anchoring proteins: A theme in signal transduction
-
Mochly-Rosen, D. Localization of protein kinases by anchoring proteins: A theme in signal transduction. Science 1995, 268: 247-51.
-
(1995)
Science
, vol.268
, pp. 247-251
-
-
Mochly-Rosen, D.1
-
139
-
-
0030813899
-
The role of anchoring protein RACK1 in PKC activation in the ageing rat brain
-
Battaini, F., Pascale, A., Paoletti, R., Govoni, S. The role of anchoring protein RACK1 in PKC activation in the ageing rat brain. Trends Neurosci 1997, 20: 410-5.
-
(1997)
Trends Neurosci
, vol.20
, pp. 410-415
-
-
Battaini, F.1
Pascale, A.2
Paoletti, R.3
Govoni, S.4
-
140
-
-
0032865258
-
Protein kinase C anchoring deficit in postmortem brains of Alzheimer's disease patients
-
Battaini, F., Pascale, A., Lucchi, L., Pasinetti, G.M., Govoni, S. Protein kinase C anchoring deficit in postmortem brains of Alzheimer's disease patients. Exp Neurol 1999, 159: 559-64.
-
(1999)
Exp Neurol
, vol.159
, pp. 559-564
-
-
Battaini, F.1
Pascale, A.2
Lucchi, L.3
Pasinetti, G.M.4
Govoni, S.5
-
141
-
-
0031985192
-
Peripheral markers in testing pathophysiological hypotheses and diagnosing Alzheimer's disease
-
Gasparini, L., Racchi, M., Binetti, G. et al. Peripheral markers in testing pathophysiological hypotheses and diagnosing Alzheimer's disease. FASEB J 1998, 12: 17-34.
-
(1998)
FASEB J
, vol.12
, pp. 17-34
-
-
Gasparini, L.1
Racchi, M.2
Binetti, G.3
-
142
-
-
0032960305
-
Regulation of amyloid precursor protein cleavage
-
Mills, J., Reiner, P.B. Regulation of amyloid precursor protein cleavage. J Neurochem 1999, 72: 443-60.
-
(1999)
J Neurochem
, vol.72
, pp. 443-460
-
-
Mills, J.1
Reiner, P.B.2
-
143
-
-
0032498135
-
Specific role for protein kinase C alpha in the constitutive and regulated secretion of amyloid precursor protein in human skin fibroblasts
-
Benussi, L., Govoni, S., Gasparini, L. et al. Specific role for protein kinase C alpha in the constitutive and regulated secretion of amyloid precursor protein in human skin fibroblasts. Neurosci Lett 1998, 240: 97-101.
-
(1998)
Neurosci Lett
, vol.240
, pp. 97-101
-
-
Benussi, L.1
Govoni, S.2
Gasparini, L.3
-
144
-
-
0028965767
-
Conventional protein kinase C (PKC)-alpha and novel PKC epsilon, but not -delta, increase the secretion of an N-terminal fragment of Alzheimer's disease amyloid precursor protein from PKC cDNA transfected 3Y1 fibroblasts
-
Kinouchi T., Sorimachi H., Maruyama K. et al. Conventional protein kinase C (PKC)-alpha and novel PKC epsilon, but not -delta, increase the secretion of an N-terminal fragment of Alzheimer's disease amyloid precursor protein from PKC cDNA transfected 3Y1 fibroblasts. FEBS Lett 1995, 364: 203-6.
-
(1995)
FEBS Lett
, vol.364
, pp. 203-206
-
-
Kinouchi, T.1
Sorimachi, H.2
Maruyama, K.3
-
145
-
-
0035951755
-
Blockade of PKC epsilon activation attenuates phorbol ester-induced increase of alpha-secretase-derived secreted form of amyloid precursor protein
-
Yeon, S.W., Jung, M.W., Ha, M.J. et al. Blockade of PKC epsilon activation attenuates phorbol ester-induced increase of alpha-secretase-derived secreted form of amyloid precursor protein. Biochem Biophys Res Commun 2001, 280: 782-7.
-
(2001)
Biochem Biophys Res Commun
, vol.280
, pp. 782-787
-
-
Yeon, S.W.1
Jung, M.W.2
Ha, M.J.3
-
146
-
-
0346848857
-
N-Propargyl-l (R)-aminoindan, rasagiline, increases glial cell line-derived neurotrophic factor (GDNF) in neuroblastoma SH-SY5Y cells through activation of NF-kappaB transcription factor
-
Maruyama, W., Nitta, A., Shamoto-Nagai, M. et al. N-Propargyl-l (R)-aminoindan, rasagiline, increases glial cell line-derived neurotrophic factor (GDNF) in neuroblastoma SH-SY5Y cells through activation of NF-kappaB transcription factor. Neurochem Int 2004, 44: 393-400.
-
(2004)
Neurochem Int
, vol.44
, pp. 393-400
-
-
Maruyama, W.1
Nitta, A.2
Shamoto-Nagai, M.3
-
147
-
-
0032590061
-
Nuclear factor-KB/Rel proteins: A point of convergence of signaling pathway relevant in neuronal function and dysfunction
-
Grilli, M., Memo, M. Nuclear factor-KB/Rel proteins: A point of convergence of signaling pathway relevant in neuronal function and dysfunction. Biochem Pharmacol 1999, 57: 1-7.
-
(1999)
Biochem Pharmacol
, vol.57
, pp. 1-7
-
-
Grilli, M.1
Memo, M.2
-
148
-
-
0030983079
-
Transcription factor NF-κB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease
-
Kaltschmidt, B., Uherek, M., Volk, B., Baeuerle, P.A., Kaltschmidt, C. Transcription factor NF-κB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease. Proc Natl Acad Sci USA 1997, 94: 2642-7.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2642-2647
-
-
Kaltschmidt, B.1
Uherek, M.2
Volk, B.3
Baeuerle, P.A.4
Kaltschmidt, C.5
-
149
-
-
0030842085
-
Nuclear translocation of NF-κB is increased in dopaminergic neurons of patients with Parkinson disease
-
Hunot, S., Brugg, B., Ricard, D. et al. Nuclear translocation of NF-κB is increased in dopaminergic neurons of patients with Parkinson disease. Proc Natl Acad Sci USA 1997, 94: 7531-6.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7531-7536
-
-
Hunot, S.1
Brugg, B.2
Ricard, D.3
-
150
-
-
0031938280
-
Nuclear factor-κB contributes to excitotoxin-induced apoptosis in rat striatum
-
Qin, Z.H., Wang, Y., Nakai, M., Chase, T.N. Nuclear factor-κB contributes to excitotoxin-induced apoptosis in rat striatum. Mol Pharmacol 1998, 53: 33-42.
-
(1998)
Mol Pharmacol
, vol.53
, pp. 33-42
-
-
Qin, Z.H.1
Wang, Y.2
Nakai, M.3
Chase, T.N.4
-
151
-
-
0035983531
-
NFκ-B-mediated up-regulation of Bcl-Xs and Bax contributes to cytochrome c release in cyanide-induced apoptosis
-
Shou, Y., Li, N., Li, L., Borowitz, J.L., Isom, G.F. NFκ-B-mediated up-regulation of Bcl-Xs and Bax contributes to cytochrome c release in cyanide-induced apoptosis. J Neurochem 2002, 81: 842-8.
-
(2002)
J Neurochem
, vol.81
, pp. 842-848
-
-
Shou, Y.1
Li, N.2
Li, L.3
Borowitz, J.L.4
Isom, G.F.5
-
152
-
-
0030026613
-
Ceramide protects hippocampal neurons against excitotoxic and oxidative insults, and amyloid beta-peptide toxicity
-
Goodman, Y., Mattson, M.P. Ceramide protects hippocampal neurons against excitotoxic and oxidative insults, and amyloid beta-peptide toxicity. J Neurochem 1996, 66: 869-72.
-
(1996)
J Neurochem
, vol.66
, pp. 869-872
-
-
Goodman, Y.1
Mattson, M.P.2
-
153
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-κB activity
-
Karin, M., Ben-Neriah, Y. Phosphorylation meets ubiquitination: The control of NF-κB activity. Ann Rev Immunol 2000, 18: 621-63.
-
(2000)
Ann Rev Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
154
-
-
0034322370
-
Suppression of NF-κB activity by sulfasalazine is mediated by direct inhibition of IκB kinases alpha and beta
-
Weber, C.K., Liptay, S., Wirth, T., Adler, G., Schinid, R.M. Suppression of NF-κB activity by sulfasalazine is mediated by direct inhibition of IκB kinases alpha and beta. Gastroenterology 2000, 119: 1209-18.
-
(2000)
Gastroenterology
, vol.119
, pp. 1209-1218
-
-
Weber, C.K.1
Liptay, S.2
Wirth, T.3
Adler, G.4
Schinid, R.M.5
-
155
-
-
0033529417
-
Inhibition of NF-κB potentiates amyloid β-mediated neuronal apoptosis
-
Kaltschmidt, B., Uherek, M., Wellmann, H., Volk, B., Kaltschmidt, C. Inhibition of NF-κB potentiates amyloid β-mediated neuronal apoptosis. Proc Natl Acad Sci USA 1999, 96: 9409-19.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 9409-9419
-
-
Kaltschmidt, B.1
Uherek, M.2
Wellmann, H.3
Volk, B.4
Kaltschmidt, C.5
-
156
-
-
85047698430
-
Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease
-
Wang, L., Muramatsu, S., Lu, Y. et al. Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease. Gene Ther 2002, 9: 381-9.
-
(2002)
Gene Ther
, vol.9
, pp. 381-389
-
-
Wang, L.1
Muramatsu, S.2
Lu, Y.3
-
157
-
-
0037096359
-
Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigro-striatal degeneration
-
Palfi, S., Leventhal, L., Chu, Y. et al. Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigro-striatal degeneration. J Neurosci 2002, 22: 4942-54.
-
(2002)
J Neurosci
, vol.22
, pp. 4942-4954
-
-
Palfi, S.1
Leventhal, L.2
Chu, Y.3
-
158
-
-
0037435511
-
Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD
-
Nutt, J.G., Burchiel, K.J., Cornelia, C.L. et al. Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD. Neurology 2003, 14: 69-73.
-
(2003)
Neurology
, vol.14
, pp. 69-73
-
-
Nutt, J.G.1
Burchiel, K.J.2
Cornelia, C.L.3
-
159
-
-
0038249170
-
Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease
-
Gill, S.S., Patel, N.K., Hotton, G.R. et al. Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nature Med 2003, 9: 589-95.
-
(2003)
Nature Med
, vol.9
, pp. 589-595
-
-
Gill, S.S.1
Patel, N.K.2
Hotton, G.R.3
|