Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 21, 1999, Pages 12108-12113

  Lin, L ^a   Georgievska, B ^a   Mattsson, A ^a   Isacson, O ^a  

^a MCLEAN HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLINERGIC SYNAPSE; COGNITION; CONTROLLED STUDY; CORPUS STRIATUM; FEMALE; HIPPOCAMPUS; MAZE TEST; NEOCORTEX; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; RAT;

AGING; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTIBODIES, MONOCLONAL; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; CEREBRAL CORTEX; CHOLINERGIC AGENTS; COGNITION; CORPUS STRIATUM; ESCAPE REACTION; FEMALE; HIPPOCAMPUS; IMMUNOTOXINS; MALE; MAZE LEARNING; MUSCARINIC AGONISTS; N-GLYCOSYL HYDROLASES; PARASYMPATHOMIMETICS; RATS; RATS, INBRED F344; RATS, SPRAGUE-DAWLEY; RECEPTORS, MUSCARINIC; SUCCINIMIDES;

EID: 0032693398     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.21.12108     Document Type: Article

References (55)

1. Terry, R. D. & Katzman, R. (1983) Ann. Neurol. 14, 497-506.
2. Coyle, J. T., Price, D. L. & DeLong, M. R. (1983) Science 219, 1184-1190.
3. Epstein, C. J. (1986) The Neurobiology of Down Syndrome (Raven, New York).
4. Epstein, C. J. (1986) The Consequences of Chromosomal Imbalance, Principles, Mechanisms, Models (Cambridge Univ. Press, New York).
5. Fiedler, J. L., Epstein, C. J., Rapoport, S. I., Caviedes, R. & Caviedes, P. (1994) Brain Res. 658, 27-32.
6. Holcomb, L., Gordon, M. N., McGowan, E., Yu, X., Benkovic, S., Jantzen, P., Wright, K., Saad, I., Mueller, R., Morgan, D., et al. (1998) Nat. Med. 4, 97-100.
7. Moran, P. M., Higgins, L. S., Cordell, B. & Moser, P. C. (1995) Proc. Natl. Acad. Sci. USA 92, 5341-5345.
8. Hsiao K., Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., Younkin, S., Yang, F. & Cole, G. (1996) Science 272, 99-102.
9. Meziane, H., Dodart, J.-C., Mathis, C., Little, S., Clemens, J., Paul, S. M. & Ungerer, A. (1998) Proc. Natl. Acad. Sci. USA 95, 12683-12688.
10. Nabeshima, T. & Nitta, A. (1994) Tohoku J. Exp. Med. 174, 241-249.
11. Maurice, T., Lockhart, B. P. & Privat, A. (1996) Brain Res. 706, 181-193.
12. Auld, D. S., Kar, S. & Quirion, R. (1998) Trends Neurosci. 21, 43-49.
13. Borchelt, D. R., Ratovitski, T., Lare, J. V., Lee, M. K., Gonzalez, V., Jinkins, N. A., Copeland, N. G., Price, D. L. & Sisodia, S. S. (1997) Neuron 19, 939-945.
14. Games, D., Adams, D., Alessandrini, R., Barbour, R., Berthelette, P., Blackwell, C., Carr, T., Clemens, J. & Donaldson, T. (1995) Nature (London) 373, 523-527.
15. Wallace, W., Ahlers, S. T., Gotlib, J., Bragin, V., Sugar, J., Gluck, R., Shea, P. A., Davis, K. L. & Haroutunian, V. (1993) Proc. Natl. Acad. Sci. USA 90, 8712-8716.
16. Beeson, J. G., Shelton, E. R., Chan, H. W. & Gage, F. H. (1994) J. Comp. Neurol. 342, 69-77.
17. Lin, L., Leblanc, C., Deacon, T. & Isacson, O. (1998) NeuroReport 9, 547-552.
18. Leanza, G. (1998) Neurosci. Lett. 257, 53-56.
19. Rossner, S., Ueberham, U., Yu, J., Kirazov, L., Reinhard, S., Perez-Polo, J. R. & Bigl, V. (1997) Eur. J. Neurosci. 9, 2125-2134.
20. Esch, F. S., Keim, P. S., Beattie, E. C., Blacher, R. W., Culwell, A. R., Oltersdorf, T., McClure, D. & Ward, P. J. (1990) Science 248, 1122-1124.
21. Haass, C., Schlossmacher, M. G., Hung, A. Y., Vigo-Pelfrey, C., Mellon, A., Ostaszewski, B. L., Lieberburg, I., Koo, E. H., Schenk, D., Teplow, D. B., et al. (1992) Nature (London) 359, 322-325.
22. Shoji, M., Golde, T. E., Ghiso, J., Cheung, T. T., Estus, S., Shaffer, L. M., Cai, X.-D., McKay, D. M., Tintner, R., Frangione, B. & Younkin, S. G. (1992) Science 258, 126-327.
23. Roberson, M. R. & Harrell, L. (1997) Brain Res. Rev. 25, 50-69.
24. Nitsch, R. M., Slack, B. E., Wurtman, R. J. & Growdon, J. H. (1992) Science 258, 304-310.
25. Hung, A. Y., Haass, C., Nitsch, R. M., Qiu, W. Q., Citron, M., Wurtman, R. J., Growdon, J. & Selkoe, D. J. (1993) J. Biol. Chem. 268, 22959-22962.
26. Nitsch, R. M. & Growdon, J. H. (1994) Biochem. Pharmacol. 47, 1275-1284.
27. Caputi, A., Barindelli, S., Pastorino, L., Cimino, M., Buxbaum, J. D., Cattabeni, F. & Luca, M. D. (1997) J. Neurochem. 68, 2523-2529.
28. Slack, B. E., Nitsch, R. M., Livneh, E., Kunz, G. M., Jr., Breu, J., Eldar, H. & Wurtman, R. J. (1993) J. Biol. Chem. 268, 21097-21101.
29. Nitsch, R. M., Deng, M., Growdon, J. H. & Wurtman, R. J. (1996) J. Biol. Chem. 271, 4188-4194.
30. Slack, B. E., Breu, J., Petryniak, M. A., Srivastava, K. & Wurtman, R. J. (1995) J. Biol. Chem. 270, 8337-8344.
31. Nitsch, R. M., Kim, C. & Growdon, J. H. (1998) Neurochem. Res. 23, 807-814.
32. Hung, A. Y. & Selkoe, D. J. (1994) EMBO J. 13, 534-542.
33. Rupniak, N. M. J., Tye, S. J. & Iversen, S. D. (1992) J. Neurol. Sci. 110, 222-227.
34. Wanibuchi, F., Konishi, T., Harada, M., Terai, M., Hidaka, K., Tamura, T., Tsukamoto, S.-i. & Usuda, S. (1990) Eur. J. Pharmacol. 187, 479-486.
35. Palacios, J. M., Bolliger, G., Closse, A., Enz, A., Gmelin, G. & Malanowski, J. (1986) Eur. J. Pharmacol. 125, 45-62.
36. Andra, J. & Lojda, Z. (1986) Histochemistry 84, 575-579.
37. Leanza, G., Nilsson, O. G., Wiley, R. G. & Bjorklund, A. (1995) Eur. J. Neurosci. 7, 329-343.
38. Neve, R. L., Rogers, J. & Higgins, G. A. (1990) Neuron 5, 329-338.
39. Jung, S. S., Nalbantoglu, J. & Cashman, N. R. (1996) J. Neurosci. Res. 46, 336-348.
40. Palmert, M. R., Podlisny, M. B., Witker, D. S., Oltersdorf, T., Younkin, L. H., Selhoe, D. J. & Younkin, S. G. (1989) Proc. Natl. Acad. Sci. USA 86, 6338-6342.
41. Wallace, W., Bragin, V., Robakis, N. K., Sambamurti, K., VanderPutten, D., Merril, C. R. & Davis, K. L. (1991) Mol. Brain Res. 10, 173-178.
42. Kalaria, R. N., Bhatti, S. U., Palatinsky, E. A., Pennington, D. H., Shelton, E. R., Chan, H. W., Perry, G. & Lust, W. D. (1993) NeuroReport 4, 211-214.
43. Banati, R. B., Gehrmann, J. & Kreutzberg, G. W. (1994) NeuroReport 5, 1359-1361.
44. Apelt, J., Schliebs, R., Beck, M., Robner, S. & Bigl, V. (1996) Int. J. Dev. Neurosci. 15, 95-112.
45. Nitsch, R. M. (1996) Neurodegeneration 5, 477-482.
46. Nitsch, R. M., Blusztaji, J. K., Pittas, A. G., Slack, B. E., Growdon, J. H. & Wurtman, R. J. (1992) Proc. Natl. Acad. Sci. USA 89, 1671-1675.
47. Jacobsen, J. S., Spruyt, M. A., Brown, A. M., Sahasrabudhe, S. R., Blume, A. J., Vitek, M. P., Muenkel, H. A. & Sonnenberg-Reines, J. (1994) J. Biol. Chem. 269, 8376-8382.
48. Gabuzda, D., Busciglio, J. & Yankner, B. A. (1993) J. Neurochem. 61, 2326-2329.
49. Caporaso, G. L., Gandy, S. E., Buxbaum, J. D., Ramabhadran, T. V. & Greengard, P. (1992) Proc. Natl. Acad. Sci. USA 89, 3055-3059.
50. Hsiao, K. K., Borchelt, D. R., Olson, K., Johannsdottir, R., Kitt, C., Yunis, W., Xu, S., Eckman, C., Younki, S., Price, D., et al. (1995) Neuron 15, 1203-1218.
51. Nalbantoglu, J., Tirado-Santiago, G., Lahsaini, A., Poirier, J., Goncalves, O., Verge, G., Momoli, F., Welner, S. A., Massicotte, G., Julien, J.-P., et al. (1997) Nature (London) 387, 500-505.
52. Kar, S., Seto, D., Gaudreau, P. & Quirion, R. (1996) J. Neurosci. 16, 1034-1040.
53. Kar, S., Issa, A. M., Seto, D., Auld, D. S., Collier, B. & Quirion, R. (1998) J. Neurochem. 70, 2179-2187.
54. Kelly, J. F., Furukawa, K., Barger, S. W., Rengen, M. R., Mark, R. J., Blanc, E. M., Roth, G. S. & Mattson, M. P. (1996) Proc. Natl. Acad. Sci. USA 93, 6753-6758.
55. Simpson, I. A., Chundu, K. R., Davies-Hill, T., Honer, W. G. & Davies, P. (1994) Ann. Neurol. 35, 546-551.