Effect of reduced myristoylated alanine-rich C kinase substrate expression on hippocampal mossy fiber development and spatial learning in mutant mice: Transgenic rescue and interactions with gene background

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 24, 1998, Pages 14517-14522

  McNamara, R K ^a,d   Stumpo, D J ^b   Morel, L M ^c   Lewis, M H ^c   Wakeland, E K ^c   Blackshear, P J ^b   Lenox, R H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Hippocampus; Macs; Protein kinase C

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; ENZYME INDUCTION; ENZYME SUBSTRATE COMPLEX; GENE EXPRESSION REGULATION; GENE MUTATION; GROWTH REGULATION; LEARNING; MOSSY FIBER; MOUSE; MYRISTYLATION; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; SPATIAL ORIENTATION;

ANIMALS; BRAIN; CEREBRAL CORTEX; CHIMERA; CROSSES, GENETIC; FEMALE; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HYPERPLASIA; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOENZYMES; LEARNING DISORDERS; MALE; MAZE LEARNING; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; MICE, TRANSGENIC; NERVE FIBERS; PROTEIN KINASE C; PROTEIN KINASE C-EPSILON; PROTEINS; PYRAMIDAL CELLS; SPACE PERCEPTION; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0032564337     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.24.14517     Document Type: Article

References (26)

1. Aderem, A. (1992) Cell 71, 713-716.
2. Barber, R. P., Vaughn, J. E., Wimer, R. E. & Wimer, C. C. (1974) J. Comp. Neurol. 156, 417-434.
3. Blackshear, P. J. (1993) J. Biol. Chem. 268, 1501-1504.
4. Bowers, B. J., Christensen, S. C., Pauley, J. R., Paylor, R., Yuva, L., Dunbar, S. E. & Wehner, J. M. (1995) J. Neurochem. 64, 2737-2746.
5. Chomczynski, P. & Sacchi, N. (1987) Anal. Biochem. 162, 156-159.
6. Crawley, J. N., Belknap, J. J., Collins, A., Crabbe, J. C., Frankel, W., Henderson, N., Hitzemann, R. J., Maxson, S. C., Miner, L. L., Silva, A. J., et al. (1997) Psychopharmacology 132, 107-124.
7. Gerlai, R. (1996) Trends Neurosci. 19, 177-181.
8. Hundle, B., McMahon, T., Dadgar, J. & Messing, R. O. (1995) J. Biol. Chem. 270, 30134-30140.
9. Kempermann, G., Kuhn, H. G. & Gage, F. H. (1997) Nature (London) 386, 493-495.
10. Lu, D., Lenox, R. H. & Raizada, M. K. (1998) J. Cell Biol., 13, 217-227.
11. McNamara, R. K., Kirkby, R. D., dePape, G. E. & Corcoran, M. E. (1992) Behav. Brain Res. 50, 65-175.
12. McNamara, R. K. & Lenox, R. H. (1997) J. Comp. Neurol. 379, 2-27.
13. McNamara, R. K. & Lenox, R. H. (1998) J. Comp. Neurol 397, 337-356.
14. Ouimet, C. C., Wang, J. K. T., Walaas, S. I., Albert, K. A. & Greengard, P. (1990) J. Neurosci. 10, 1683-1698.
15. Saito, N., Itouji, A., Totani, Y., Osawa, I., Koide, H., Fujisawa, N., Ogita, K. & Tanaka, C. (1993) Brain Res. 607, 241-248.
16. Schopke, R., Wolfer, D. P., Lipp, H.-P. & Leisinger-Trigona, M.-C. (1991) Hippocampus 1, 315-328.
17. Schwegler, H. & Crusio, W. E. (1995) Behav. Brain Res. 67, 29-41.
18. Schwegler, H. & Lipp, H.-P. (1983) Behav. Brain Res. 7, 1-38.
19. Seykora, J. T., Ravetch, J. V. & Aderem, A. (1991) Proc. Natl. Acad. Sci. USA 88, 2505-2509.
20. Stumpo, D. J., Bock, C. B., Tuttle, J. S. & Blackshear, P. J. (1995) Proc. Natl. Acad. Sci. USA 92, 944-948.
21. Swierczynski, S. L., Siddhanti, S. R., Tuttle, J. S. & Blackshear, P. J. (1996) Dev. Biol. 179, 135-147.
22. Threadgill, D. W., Dlugosz, A. A., Hansen, L. A., Tennenbaum, T., Lichti, U., Yee, D., LaMantia, C., Mourton, T., Herrup, K., Harris, R. C., et al. (1995) Science 269, 230-234.
23. Umberall, F., Giselbrecht, S., Hellbert, K., Fresser, F., Bauer, B., Gschwendt, M., Grunicke, H. H. & Baier, G. (1997) J. Biol. Chem. 272, 4072-4078.
24. Van der Zee, E. A. & Douma, B. R. (1997) Prog. Neuropsychopharmacol. Biol. Psychiatry 21, 379-406.
25. Watson, D. G., Watterson, J. M & Lenox, R. H. (1998) J. Pharmacol. Exp. Ther. 285, 307-316.
26. Wehner, J. M., Sleight, S. & Upchurch, M. (1990) Brain Res. 523, 181-187.