Blockade of PKCε activation attenuates phorbol ester-induced increase of α-secretase-derived secreted form of amyloid precursor protein

Biochemical and Biophysical Research Communications

Volumn 280, Issue 3, 2001, Pages 782-787

  Yeon, Seung Woo ^a   Jung, Min Whan ^a   Ha, Man Joon ^a   Kim, Seung Up ^a   Huh, Kyoon ^a   Savage, Mary J ^b   Masliah, Eliezer ^c   Mook Jung, Inhee ^a,c  

^a Ajou University School of Medicine   (South Korea)

^b CEPHALON INC   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer s disease; APP; PKC ; RACK; sAPP; amyloid

Indexed keywords

AMYLOID PRECURSOR PROTEIN; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; ISOENZYME; PHORBOL DIBUTYRATE; PRIMER DNA; PRKCE PROTEIN, HUMAN; PRKCE PROTEIN, RAT; PROTEIN KINASE C; PROTEIN KINASE C EPSILON; PROTEINASE; SECRETASE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; AMYLOID BETA PROTEIN; COMPLEMENTARY DNA; PROTEIN KINASE C ACTIVATOR; PROTEIN KINASE C INHIBITOR;

ALZHEIMER DISEASE; ANIMAL; ARTICLE; BRAIN; CASE CONTROL STUDY; CELL LINE; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; NUCLEOTIDE SEQUENCE; PROTEIN PROCESSING; RAT; SECRETION; BRAIN LEVEL; CELL FRACTIONATION; CONTROLLED STUDY; DNA SEQUENCE; HUMAN CELL; NEUROLOGIC DISEASE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BASE SEQUENCE; BRAIN; CASE-CONTROL STUDIES; CELL LINE; DNA PRIMERS; ENDOPEPTIDASES; ENZYME ACTIVATION; HUMANS; ISOENZYMES; PHORBOL 12,13-DIBUTYRATE; PROTEIN KINASE C; PROTEIN KINASE C-EPSILON; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; TRANSFECTION;

EID: 0035951755     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.4181     Document Type: Article

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