Drug-associated mitochondrial toxicity and its detection

Current Medicinal Chemistry

Volumn 12, Issue 16, 2005, Pages 1829-1839

  Amacher, David E ^a  

^a PFIZER INC   (United States)

Author keywords

Hepatotoxicity; Liver; Mitochondria; Review

Indexed keywords

2,4 DINITROPHENOL; 7 BENZYL 3 THIA 7 AZABICYCLO[3.3.1]NONANE; ACULEXIMYCIN; AMIODARONE; ANESTHETIC AGENT; ANTIANGINA PECTORIS AGENT; ANTIHISTAMINIC AGENT; ANTIINFECTIVE AGENT; ANTIMYCIN A1; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; CLOMIPRAMINE; DOXORUBICIN; FUNICULOSIN; IMIPRAMINE; LIDOCAINE; LOCAL ANESTHETIC AGENT; MYXOTHIAZOL; NEUROLEPTIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; PROPRANOLOL; PSYCHOTROPIC AGENT; QUINIDINE; QUINOLONE DERIVATIVE; TACRINE; TRICYCLIC ANTIDEPRESSANT AGENT; UNCOUPLING PROTEIN; UNINDEXED DRUG; XENOBIOTIC AGENT; ZINC;

AGING; ALZHEIMER DISEASE; APOPTOSIS; BONE DISEASE; CARDIOTOXICITY; CELL ASSAY; CELL FUNCTION; CENTRAL NERVOUS SYSTEM DISEASE; CHEMICAL STRUCTURE; DIABETES MELLITUS; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG SYNTHESIS; HOMEOSTASIS; HYPERGLYCEMIA; LIVER TOXICITY; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL TOXICITY; NONHUMAN; PARKINSON DISEASE; PATHOGENESIS; PREDICTION; QUANTITATIVE ANALYSIS; REPERFUSION INJURY; REVIEW; SENSITIVITY ANALYSIS;

ANIMALS; DRUG TOXICITY; HUMANS; INTRACELLULAR MEMBRANES; MEMBRANE POTENTIALS; MITOCHONDRIA;

EID: 22544477523     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867054546663     Document Type: Review

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