JLK inhibitors: Isocoumarin compounds as putative probes to selectively target the γ-secretase pathway

Current Alzheimer Research

Volumn 2, Issue 3, 2005, Pages 327-334

  Checler, Frédéric ^a,b   Alves Da Costa, Cristine ^a   Ayral, Erwan ^b   Andrau, David ^a   Dumanchin, Cécile ^a,c   Farzan, Michael ^d   Hernandez, Jean François ^b   Martinez, J ^b   Solveig, Lefranc Jullien ^a   Marambaud, Philippe ^e   Pasini, Andrea ^f   Petit, Agnès ^a   Phiel, Christopher ^g   Robert, Philippe ^h   St George Hyslop, Peter ⁱ   Wilk, Sherwin ^j  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b CNRS   (France)

^c INSERM   (France)

^d HARVARD MEDICAL SCHOOL   (United States)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^f AIX MARSEILLE UNIVERSITÉ   (France)

^g HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^h UNIVERSITY HOSPITAL OF NICE   (France)

ⁱ Tanz Neurosciences Building ^*  (Canada)

^j MOUNT SINAI SCHOOL OF MEDICINE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; GLYCOGEN SYNTHASE KINASE 3BETA; ISOCOUMARIN DERIVATIVE; JLK INHIBITOR; NERVE CELL ADHESION MOLECULE; NOTCH RECEPTOR; PRESENILIN 1; UNCLASSIFIED DRUG; UVOMORULIN;

ALZHEIMER DISEASE; CONFERENCE PAPER; DRUG DESIGN; DRUG STRUCTURE; ENZYME ACTIVITY; HUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

AMYLOID BETA-PROTEIN; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; COUMARINS; ENDOPEPTIDASES; ENZYME INHIBITORS; HUMANS; ISOMERISM; MOLECULAR PROBES;

EID: 22144445228     PISSN: 15672050     EISSN: None     Source Type: Journal    
DOI: 10.2174/1567205054367874     Document Type: Conference Paper

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