Presenilin-dependent γ-secretase activity mediates the intramembranous cleavage of CD44

Oncogene

Volumn 22, Issue 10, 2003, Pages 1511-1516

  Murakami, Daizo ^a   Okamoto, Isamu ^a   Nagano, Osamu ^a   Kawano, Yoshiaki ^a   Tomita, Taisuke ^b   Iwatsubo, Takeshi ^b   De Strooper, Bart ^c   Yumoto, Eiji ^a   Saya, Hideyuki ^a  

^a KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

secretase; CD44; Intramembranous cleavage; Presenilin

Indexed keywords

CELL ADHESION MOLECULE; GAMMA SECRETASE; HERMES ANTIGEN; PHORBOL 13 ACETATE 12 MYRISTATE; PRESENILIN 1;

ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; EXTRACELLULAR MATRIX; FIBROBLAST; GENE FUNCTION; HUMAN; HUMAN CELL; METASTASIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; TUMOR GROWTH;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANTIGENS, CD44; ASPARTIC ENDOPEPTIDASES; CARBAMATES; CELL MEMBRANE; CENTRAL NERVOUS SYSTEM NEOPLASMS; DIPEPTIDES; EMBRYO; ENDOPEPTIDASES; FIBROBLASTS; GLIOMA; HUMANS; LEUPEPTINS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; PEPSTATINS; PRESENILIN-1; PROTEASE INHIBITORS; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; TUMOR CELLS, CULTURED;

EID: 0037435016     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206298     Document Type: Article

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