-
1
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994; 266:66-71.
-
(1994)
Science
, vol.266
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
Futreal, P.A.4
Harshman, K.5
Tavtigian, S.6
-
2
-
-
0031033343
-
Mutations and alternative splicing of the BRCA1 gene in UK breast/ovarian cancer families
-
Xu C-F, Chambers JA, Nicolai H, Brown MA, Jujeirat Y, Mohammed S, et al. Mutations and alternative splicing of the BRCA1 gene in UK breast/ovarian cancer families. Genes Chromosomes Cancer 1997; 18:102-10.
-
(1997)
Genes Chromosomes Cancer
, vol.18
, pp. 102-110
-
-
Xu, C.-F.1
Chambers, J.A.2
Nicolai, H.3
Brown, M.A.4
Jujeirat, Y.5
Mohammed, S.6
-
3
-
-
0031812658
-
Breast cancer susceptibility genes BRCA1 and BRCA2
-
Brody LC, Biesecker BB. Breast cancer susceptibility genes BRCA1 and BRCA2. Baltimore: Medicine 1998:77:208-26.
-
(1998)
Baltimore: Medicine
, vol.77
, pp. 208-226
-
-
Brody, L.C.1
Biesecker, B.B.2
-
4
-
-
0036178190
-
Current understanding of the epidemiology and clinical implications of BRCA1 and BRCA2 mutations for ovarian cancer
-
Narod SA, Boyd J. Current understanding of the epidemiology and clinical implications of BRCA1 and BRCA2 mutations for ovarian cancer. Curr Opin Obstet Gynecol 2002; 14:19-26.
-
(2002)
Curr Opin Obstet Gynecol
, vol.14
, pp. 19-26
-
-
Narod, S.A.1
Boyd, J.2
-
5
-
-
0033590179
-
DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis
-
Dasika GK, Lee EY-HP. DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis. Oncogene 1999; 18:7883-99.
-
(1999)
Oncogene
, vol.18
, pp. 7883-7899
-
-
Dasika, G.K.1
Lee, E.Y.-H.P.2
-
6
-
-
0037115914
-
Homologous repair of DNA damage and tumorigenesis: The BRCA connection
-
Jasin M. Homologous repair of DNA damage and tumorigenesis: The BRCA connection. Oncogene 2002; 21:8981-93.
-
(2002)
Oncogene
, vol.21
, pp. 8981-8993
-
-
Jasin, M.1
-
7
-
-
0037389507
-
Roles of BRCA1 in DNA damage repair: A link between development and cancer
-
Deng CX, Wang RH. Roles of BRCA1 in DNA damage repair: A link between development and cancer. Hum Mol Genet 2003; 12:R113-23.
-
(2003)
Hum Mol Genet
, vol.12
-
-
Deng, C.X.1
Wang, R.H.2
-
8
-
-
1942502234
-
Tracing the network connecting BRCA and fanconi anaemia proteins
-
Venkitaraman AR. Tracing the network connecting BRCA and fanconi anaemia proteins. Nat Rev Cancer 2004; 4:266-76.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 266-276
-
-
Venkitaraman, A.R.1
-
9
-
-
7844247959
-
p53 mutation with frequent novel codons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours
-
Crook T, Brooks LA, Crossland S, Osin P, Barker KT, Waller JPE, et al. p53 mutation with frequent novel codons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours. Oncogene 1998; 17:1681-9.
-
(1998)
Oncogene
, vol.17
, pp. 1681-1689
-
-
Crook, T.1
Brooks, L.A.2
Crossland, S.3
Osin, P.4
Barker, K.T.5
Waller, J.P.E.6
-
10
-
-
0033518891
-
Frequency of p53 mutations in breast carcinomas from Ashkenazi Jewish carriers of BRCA1 mutations
-
Phillips KA, Nichol K, Ozcelik H, Knight J, Done SJ, Goodwin PJ, et al. Frequency of p53 mutations in breast carcinomas from Ashkenazi Jewish carriers of BRCA1 mutations. J Natl Cancer Inst 1999; 469-73.
-
(1999)
J Natl Cancer Inst
, pp. 469-473
-
-
Phillips, K.A.1
Nichol, K.2
Ozcelik, H.3
Knight, J.4
Done, S.J.5
Goodwin, P.J.6
-
11
-
-
0030981170
-
Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation
-
Hakem R, de la Pompa JL, Elia A, Potter J, Mak TW. Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation. Nat Genet 1997; 16:298-302.
-
(1997)
Nat Genet
, vol.16
, pp. 298-302
-
-
Hakem, R.1
De La Pompa, J.L.2
Elia, A.3
Potter, J.4
Mak, T.W.5
-
12
-
-
0030924656
-
Targeted mutations of breast cancer susceptibility gene homologs in mice: Lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos
-
Ludwig T, Chapman DL, Papaioannou VE, Efstratiadis A. Targeted mutations of breast cancer susceptibility gene homologs in mice: Lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos. Genes Dev 1997; 11:1226-41.
-
(1997)
Genes Dev
, vol.11
, pp. 1226-1241
-
-
Ludwig, T.1
Chapman, D.L.2
Papaioannou, V.E.3
Efstratiadis, A.4
-
13
-
-
0034946638
-
Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis
-
Xu X, Qiao W, Linke SP, Cao L, Li WM, Furth PA, et al. Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis. Nat Genet 2001; 28:266-71.
-
(2001)
Nat Genet
, vol.28
, pp. 266-271
-
-
Xu, X.1
Qiao, W.2
Linke, S.P.3
Cao, L.4
Li, W.M.5
Furth, P.A.6
-
14
-
-
0035829651
-
Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice
-
Brodie SG, Xu X, Qiao W, Li WM, Cao L, Deng CX. Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice. Oncogene 2001; 20:7514-23.
-
(2001)
Oncogene
, vol.20
, pp. 7514-7523
-
-
Brodie, S.G.1
Xu, X.2
Qiao, W.3
Li, W.M.4
Cao, L.5
Deng, C.X.6
-
15
-
-
0038209424
-
BRCA1 shifts p53-mediated cellular outcomes towards irreversible growth arrest
-
Ongusaha PP, Ouchi T, Kim KT, Nytko E, Kwak JC, Duda RB, et al. BRCA1 shifts p53-mediated cellular outcomes towards irreversible growth arrest. Oncogene 2003; 22:3749-58.
-
(2003)
Oncogene
, vol.22
, pp. 3749-3758
-
-
Ongusaha, P.P.1
Ouchi, T.2
Kim, K.T.3
Nytko, E.4
Kwak, J.C.5
Duda, R.B.6
-
17
-
-
2942687831
-
Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway
-
Kitagawa R, Bakkenist CJ, McKinnon PJ, Kastan MB. Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway. Genes Dev 2004; 18:1423-38.
-
(2004)
Genes Dev
, vol.18
, pp. 1423-1438
-
-
Kitagawa, R.1
Bakkenist, C.J.2
McKinnon, P.J.3
Kastan, M.B.4
-
18
-
-
0034655991
-
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
-
Wang Y, Cortez D, Yazdi P, Neff N, Elledge SJ, Qin J. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev 2000; 14:927-39.
-
(2000)
Genes Dev
, vol.14
, pp. 927-939
-
-
Wang, Y.1
Cortez, D.2
Yazdi, P.3
Neff, N.4
Elledge, S.J.5
Qin, J.6
-
19
-
-
0030048511
-
High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines
-
Luo CM, Tang KW, Mekeel L, DeFrank JS, Anne PR, Powell SN. High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines. J Biol Chem 1996; 271:4497-503.
-
(1996)
J Biol Chem
, vol.271
, pp. 4497-4503
-
-
Luo, C.M.1
Tang, K.W.2
Mekeel, L.3
DeFrank, J.S.4
Anne, P.R.5
Powell, S.N.6
-
20
-
-
0034624718
-
hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response
-
Lee JS, Collins KM, Brown AL, Lee CH, Chung JH. hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response. Nature 2000; 404:201-4.
-
(2000)
Nature
, vol.404
, pp. 201-204
-
-
Lee, J.S.1
Collins, K.M.2
Brown, A.L.3
Lee, C.H.4
Chung, J.H.5
-
21
-
-
0035890407
-
Destabilization of CHK2 by a missense mutation associated with Li-Fraumeni Syndrome
-
Lee SB, Kim SH, Bell DW, Wahrer DC, Schiripo TA, Jorczak MM, et al. Destabilization of CHK2 by a missense mutation associated with Li-Fraumeni Syndrome. Cancer Res 2001; 61:8062-7.
-
(2001)
Cancer Res
, vol.61
, pp. 8062-8067
-
-
Lee, S.B.1
Kim, S.H.2
Bell, D.W.3
Wahrer, D.C.4
Schiripo, T.A.5
Jorczak, M.M.6
-
22
-
-
0346095320
-
Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair
-
Zhang J, Willers H, Feng Z, Ghosh JC, Kim S, Weaver DT, et al. Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair. Mol Cell Biol 2004; 24:708-18.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 708-718
-
-
Zhang, J.1
Willers, H.2
Feng, Z.3
Ghosh, J.C.4
Kim, S.5
Weaver, D.T.6
-
23
-
-
0037711771
-
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
-
Celeste A, Fernandez-Capetillo O, Kruhlak MJ, Pilch DR, Staudt DW, Lee A, et al. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. Nat Cell Biol 2003; 5:675-9.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 675-679
-
-
Celeste, A.1
Fernandez-Capetillo, O.2
Kruhlak, M.J.3
Pilch, D.R.4
Staudt, D.W.5
Lee, A.6
-
24
-
-
0346634937
-
H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis
-
Fernandez-Capetillo O, Mahadevaiah SK, Celeste A, Romanienko PJ, Camerini-Otero RD, Bonner WM, et al. H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis. Dev Cell 2003; 4:497-508.
-
(2003)
Dev Cell
, vol.4
, pp. 497-508
-
-
Fernandez-Capetillo, O.1
Mahadevaiah, S.K.2
Celeste, A.3
Romanienko, P.J.4
Camerini-Otero, R.D.5
Bonner, W.M.6
-
25
-
-
0037062492
-
Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX
-
USA
-
Bassing CH, Chua KF, Sekiguchi J, Suh H, Whitlow SR, Fleming JC, et al. Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX. Proc Natl Acad Sci USA 2002; 99:8173-8.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 8173-8178
-
-
Bassing, C.H.1
Chua, K.F.2
Sekiguchi, J.3
Suh, H.4
Whitlow, S.R.5
Fleming, J.C.6
-
26
-
-
0030850047
-
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
-
Scully R, Chen J, Ochs RL, Keegan K, Hoekstra M, Feunteun J, et al. Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell 1997; 90:425-35.
-
(1997)
Cell
, vol.90
, pp. 425-435
-
-
Scully, R.1
Chen, J.2
Ochs, R.L.3
Keegan, K.4
Hoekstra, M.5
Feunteun, J.6
-
27
-
-
0030965157
-
BRCA1 is a component of the RNA polymerase II holoenzyme
-
USA
-
Scully R, Anderson SF, Chao DM, Ye L, Young RA, Livingston DM, et al. BRCA1 is a component of the RNA polymerase II holoenzyme. Proc Natl Acad Sci USA 1997; 94:5605-10.
-
(1997)
Proc Natl Acad Sci
, vol.94
, pp. 5605-5610
-
-
Scully, R.1
Anderson, S.F.2
Chao, D.M.3
Ye, L.4
Young, R.A.5
Livingston, D.M.6
-
28
-
-
0346732323
-
BRCA1 associates with processive RNA polymerase II
-
Krum SA, Miranda GA, Lin C, Lane TF. BRCA1 associates with processive RNA polymerase II. J Biol Chem 2003; 278:52012-20.
-
(2003)
J Biol Chem
, vol.278
, pp. 52012-52020
-
-
Krum, S.A.1
Miranda, G.A.2
Lin, C.3
Lane, T.F.4
-
29
-
-
0031830844
-
BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A
-
Anderson SF, Schlegal BP, Nakajima T, Wolpin ES, Parvin JD. BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A. Nature Genetics 1998; 19:254-6.
-
(1998)
Nature Genetics
, vol.19
, pp. 254-256
-
-
Anderson, S.F.1
Schlegal, B.P.2
Nakajima, T.3
Wolpin, E.S.4
Parvin, J.D.5
-
30
-
-
0037455691
-
Overexpression of a protein fragment of RNA helicase a causes inhibition of endogenous BRCA1 function and defects in ploidy and cytokinesis in mammary epithelial cells
-
Schlegel BP, Starita LM, Parvin JD. Overexpression of a protein fragment of RNA helicase A causes inhibition of endogenous BRCA1 function and defects in ploidy and cytokinesis in mammary epithelial cells. Oncogene 2003; 22:983-91.
-
(2003)
Oncogene
, vol.22
, pp. 983-991
-
-
Schlegel, B.P.1
Starita, L.M.2
Parvin, J.D.3
-
31
-
-
3142691271
-
BRCA1 cooperates with NUFIP and P-TEFb to activate transcription by RNA polymerase II
-
Epub ahead of print
-
Cabart P, Chew HK, Murphy S. BRCA1 cooperates with NUFIP and P-TEFb to activate transcription by RNA polymerase II. Oncogene 2004; Epub ahead of print.
-
(2004)
Oncogene
-
-
Cabart, P.1
Chew, H.K.2
Murphy, S.3
-
32
-
-
0035815612
-
Three RNA polymerase II carboxyl-terminal domain kinases display distinct substrate preferences
-
Ramanathan Y, Rajpara SM, Reza SM, Lees E, Shuman S, Mathews MB, et al. Three RNA polymerase II carboxyl-terminal domain kinases display distinct substrate preferences. J Biol Chem 2001; 276:10913-20.
-
(2001)
J Biol Chem
, vol.276
, pp. 10913-10920
-
-
Ramanathan, Y.1
Rajpara, S.M.2
Reza, S.M.3
Lees, E.4
Shuman, S.5
Mathews, M.B.6
-
33
-
-
0037684805
-
The multiple nuclear functions of BRCA1: Transcription, ubiquitination and DNA repair
-
Starita LM, Parvin JD. The multiple nuclear functions of BRCA1: Transcription, ubiquitination and DNA repair. Curr Opin Cell Biol 2003; 15:345-50.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 345-350
-
-
Starita, L.M.1
Parvin, J.D.2
-
34
-
-
0034724274
-
BRCA1 interaction with RNA polymerase II reveals a role for hRPB2 and hRPB10α in activated transcription
-
USA
-
Schlegel BP, Green VJ, Ladias JA, Parvin JD. BRCA1 interaction with RNA polymerase II reveals a role for hRPB2 and hRPB10α in activated transcription. Proc Natl Acad Sci USA 2000; 97:3148-53.
-
(2000)
Proc Natl Acad Sci
, vol.97
, pp. 3148-3153
-
-
Schlegel, B.P.1
Green, V.J.2
Ladias, J.A.3
Parvin, J.D.4
-
36
-
-
0034707053
-
In search of the tumour-suppressor functions of BRCA1 and BRCA2
-
Scully R, Livingston DM. In search of the tumour-suppressor functions of BRCA1 and BRCA2. Nature 2000; 408:429-32.
-
(2000)
Nature
, vol.408
, pp. 429-432
-
-
Scully, R.1
Livingston, D.M.2
-
37
-
-
0037048290
-
Roles of BRCA1 in centrosome duplication
-
Deng CX. Roles of BRCA1 in centrosome duplication. Oncogene 2002; 21:6222-7.
-
(2002)
Oncogene
, vol.21
, pp. 6222-6227
-
-
Deng, C.X.1
-
38
-
-
0034697973
-
BRCA1 is associated with a human SWI/SNF-related complex: Linking chromatin remodeling to breast cancer
-
Bochar DA, Shiekhattar R. BRCA1 is associated with a human SWI/SNF-related complex: Linking chromatin remodeling to breast cancer. Cell 2000; 102:257-65.
-
(2000)
Cell
, vol.102
, pp. 257-265
-
-
Bochar, D.A.1
Shiekhattar, R.2
-
39
-
-
0035842893
-
BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations
-
Ye Q, Hu YF, Zhong Nye AC, Belmont AS, Li R. BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations. J Biol Chem 2001; 155:911-21.
-
(2001)
J Biol Chem
, vol.155
, pp. 911-921
-
-
Ye, Q.1
Hu, Y.F.2
Zhong Nye, A.C.3
Belmont, A.S.4
Li, R.5
-
40
-
-
18744372123
-
BRCA1 supports XIST RNA concentration on the inactive X chromosome
-
Ganesan S, Silver DP, Greenberg RA, Avni D, Drapkin R, Miron A, et al. BRCA1 supports XIST RNA concentration on the inactive X chromosome. Cell 2002; 111:393-405.
-
(2002)
Cell
, vol.111
, pp. 393-405
-
-
Ganesan, S.1
Silver, D.P.2
Greenberg, R.A.3
Avni, D.4
Drapkin, R.5
Miron, A.6
-
41
-
-
0035805582
-
The ring heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a brest cancer-derived mutation
-
Hashizume R, Fukuda M, Maeda I, Yabuki Y, Ogata H, Ohta T. The ring heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a brest cancer-derived mutation. J Biol Chem 2001; 276:14537-40.
-
(2001)
J Biol Chem
, vol.276
, pp. 14537-14540
-
-
Hashizume, R.1
Fukuda, M.2
Maeda, I.3
Yabuki, Y.4
Ogata, H.5
Ohta, T.6
-
42
-
-
0035942190
-
Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity
-
USA
-
Ruffner H, Joazeiro CA, Hemmati D, Hunter T, Verma IM. Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity. Proc Natl Acad Sci USA 2001; 98:5134-9.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 5134-5139
-
-
Ruffner, H.1
Joazeiro, C.A.2
Hemmati, D.3
Hunter, T.4
Verma, I.M.5
-
43
-
-
0037122004
-
Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains
-
Mallery DL, Vandenberg CJ, Hiom K. Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains. EMBO J 2002; 21:6755-62.
-
(2002)
EMBO J
, vol.21
, pp. 6755-6762
-
-
Mallery, D.L.1
Vandenberg, C.J.2
Hiom, K.3
-
44
-
-
0037610801
-
Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex
-
USA
-
Brzovic PS, Keeffe JR, Nishikawa H, Miyamoto K, Fox IIIrd D, Fukuda M, et al. Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex. Proc Natl Acad Sci USA 2003; 100:5646-51.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 5646-5651
-
-
Brzovic, P.S.1
Keeffe, J.R.2
Nishikawa, H.3
Miyamoto, K.4
Fox III, D.5
Fukuda, M.6
-
45
-
-
0037102275
-
Phosphorylation of serine 1387 in Brca1 is specifically required for the atm-mediated S-phase checkpoint after ionizing irradiation
-
Xu B, O'Donnell AH, Kim ST, Kastan MB. Phosphorylation of serine 1387 in Brca1 is specifically required for the atm-mediated S-phase checkpoint after ionizing irradiation. Cancer Res 2002; 62:4588-91.
-
(2002)
Cancer Res
, vol.62
, pp. 4588-4591
-
-
Xu, B.1
O'Donnell, A.H.2
Kim, S.T.3
Kastan, M.B.4
-
46
-
-
0141730305
-
Bovine BRCA1 shows classic responses to genotoxic stress but low in vitro transcriptional activation activity
-
Krum SA, Womack JE, Lane TF. Bovine BRCA1 shows classic responses to genotoxic stress but low in vitro transcriptional activation activity. Oncogene 2003; 22:6032-44.
-
(2003)
Oncogene
, vol.22
, pp. 6032-6044
-
-
Krum, S.A.1
Womack, J.E.2
Lane, T.F.3
-
47
-
-
0036490136
-
Participation of BRCA1 in the DNA repair response via transcription
-
Monteiro AN. Participation of BRCA1 in the DNA repair response via transcription. Cancer Biol Ther 2002; 1:187-8.
-
(2002)
Cancer Biol Ther
, vol.1
, pp. 187-188
-
-
Monteiro, A.N.1
-
48
-
-
0012668180
-
Transactivation of repair genes by BRCA1
-
El-Deiry WS. Transactivation of repair genes by BRCA1. Cancer Biol Ther 2002; 1:490-1.
-
(2002)
Cancer Biol Ther
, vol.1
, pp. 490-491
-
-
El-Deiry, W.S.1
-
49
-
-
0029830051
-
Transcriptional activation by BRCA1
-
Chapman MS, Verma IM. Transcriptional activation by BRCA1. Nature 1996; 382:678-9.
-
(1996)
Nature
, vol.382
, pp. 678-679
-
-
Chapman, M.S.1
Verma, I.M.2
-
50
-
-
0030474170
-
Evidence for a transcriptional activation function of BRCA1 C-terminal region
-
USA
-
Monteiro ANA, August A, Hanafusa H. Evidence for a transcriptional activation function of BRCA1 C-terminal region. Proc Natl Acad Sci USA 1996; 93:13595-9.
-
(1996)
Proc Natl Acad Sci
, vol.93
, pp. 13595-13599
-
-
Monteiro, A.N.A.1
August, A.2
Hanafusa, H.3
-
51
-
-
21644474840
-
Methods to classify BRCA1 variants of uncertain clinical significance: The more the merrier
-
Billack B, Monteiro AN. Methods to classify BRCA1 variants of uncertain clinical significance: The more the merrier. Cancer Biol Ther 2004; 3:458-9.
-
(2004)
Cancer Biol Ther
, vol.3
, pp. 458-459
-
-
Billack, B.1
Monteiro, A.N.2
-
52
-
-
0036682183
-
The BRCA1 and BARD1 association with the RNA polymerase II holoenzyme
-
Chiba N, Parvin JD. The BRCA1 and BARD1 association with the RNA polymerase II holoenzyme. Cancer Res 2002; 62:4222-8.
-
(2002)
Cancer Res
, vol.62
, pp. 4222-4228
-
-
Chiba, N.1
Parvin, J.D.2
-
53
-
-
0034306456
-
BRCA1: Exploring the links to transcription
-
Monteiro AN. BRCA1: Exploring the links to transcription. Trends Biochem Sci 2000; 25:469-74.
-
(2000)
Trends Biochem Sci
, vol.25
, pp. 469-474
-
-
Monteiro, A.N.1
-
54
-
-
0037040920
-
BRCA1 regulates GADD45 through its interactions with the OCT-1 and CAAT motifs
-
Fan W, Jin S, Tong T, Zhao H, Fan F, Antinore MJ, et al. BRCA1 regulates GADD45 through its interactions with the OCT-1 and CAAT motifs. J Biol Chem 2002; 277:8061-7.
-
(2002)
J Biol Chem
, vol.277
, pp. 8061-8067
-
-
Fan, W.1
Jin, S.2
Tong, T.3
Zhao, H.4
Fan, F.5
Antinore, M.J.6
-
55
-
-
0033967218
-
CBP/p300 interact with and function as transcriptional coactivators of BRCA1
-
USA
-
Pao GM, Janknecht R, Ruffner H, Hunter T, Verma IM. CBP/p300 interact with and function as transcriptional coactivators of BRCA1. Proc Natl Acad Sci USA 2000; 97:1020-5.
-
(2000)
Proc Natl Acad Sci
, vol.97
, pp. 1020-1025
-
-
Pao, G.M.1
Janknecht, R.2
Ruffner, H.3
Hunter, T.4
Verma, I.M.5
-
56
-
-
0033591295
-
BRCA1 inhibition of estrogen receptor signaling in transfected cells
-
Fan S, Wang J, Yuan R, Ma Y, Meng Q, Erdos MR, et al. BRCA1 inhibition of estrogen receptor signaling in transfected cells. Science 1999; 284:1354-6.
-
(1999)
Science
, vol.284
, pp. 1354-1356
-
-
Fan, S.1
Wang, J.2
Yuan, R.3
Ma, Y.4
Meng, Q.5
Erdos, M.R.6
-
57
-
-
0033637860
-
Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1
-
Zheng L, Pan H, Li S, Flesken-Nikitin A, Chen PL, Boyer TG, et al. Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1. Mol Cell 2000; 6:757-68.
-
(2000)
Mol Cell
, vol.6
, pp. 757-768
-
-
Zheng, L.1
Pan, H.2
Li, S.3
Flesken-Nikitin, A.4
Chen, P.L.5
Boyer, T.G.6
-
58
-
-
0038719698
-
Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter
-
Baker KM, Wei G, Schaffner AE, Ostrowski MC. Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter. J Biol Chem 2003; 278:17876-84.
-
(2003)
J Biol Chem
, vol.278
, pp. 17876-17884
-
-
Baker, K.M.1
Wei, G.2
Schaffner, A.E.3
Ostrowski, M.C.4
-
59
-
-
0036644843
-
A common DNA-binding site for SZF1 and the BRCA1-associated zinc finger protein, ZBRK1
-
Peng H, Zheng L, Lee WH, JJ R, Rauscher IIIrd FJ. A common DNA-binding site for SZF1 and the BRCA1-associated zinc finger protein, ZBRK1. Cancer Res 2002; 62:3773-81.
-
(2002)
Cancer Res
, vol.62
, pp. 3773-3781
-
-
Peng, H.1
Zheng, L.2
Lee, W.H.3
Jj, R.4
Rauscher III, F.J.5
-
60
-
-
0035831030
-
The BARD1-CstF-50 interaction links mRNA 3′ end formation to DNA damage and tumor suppression
-
Kleiman FE, Manley JL. The BARD1-CstF-50 interaction links mRNA 3′ end formation to DNA damage and tumor suppression. Cell 2001; 104:743-53.
-
(2001)
Cell
, vol.104
, pp. 743-753
-
-
Kleiman, F.E.1
Manley, J.L.2
-
61
-
-
0001221269
-
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
-
Kleiman FE, Manley JL. Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50. Science 1999; 285:1576-9.
-
(1999)
Science
, vol.285
, pp. 1576-1579
-
-
Kleiman, F.E.1
Manley, J.L.2
-
62
-
-
0033612303
-
Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1
-
Harkin DP, Bean JM, Miklos D, Song YH, Truong VB, Englert C, et al. Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1. Cell 1999; 97:575-86.
-
(1999)
Cell
, vol.97
, pp. 575-586
-
-
Harkin, D.P.1
Bean, J.M.2
Miklos, D.3
Song, Y.H.4
Truong, V.B.5
Englert, C.6
-
63
-
-
0037188479
-
BRCA1 transcriptionally regulates genes involved in breast tumorigenesis
-
USA
-
Welcsh PL, Lee MK, Gonzalez-Hernandez RM, Black DJ, Mahadevappa M, Swisher EM, et al. BRCA1 transcriptionally regulates genes involved in breast tumorigenesis. Proc Natl Acad Sci USA 2002; 99:7560-5.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 7560-7565
-
-
Welcsh, P.L.1
Lee, M.K.2
Gonzalez-Hernandez, R.M.3
Black, D.J.4
Mahadevappa, M.5
Swisher, E.M.6
-
64
-
-
0034680038
-
BRCA1 activation of the GADD45 promoter
-
Jin S, Zhao H, Fan F, Blanck P, Fan W, Colchagie AB, et al. BRCA1 activation of the GADD45 promoter. Oncogene 2000; 19:4050-7.
-
(2000)
Oncogene
, vol.19
, pp. 4050-4057
-
-
Jin, S.1
Zhao, H.2
Fan, F.3
Blanck, P.4
Fan, W.5
Colchagie, A.B.6
-
65
-
-
0035210180
-
Uncovering BRCA1-regulated signalling pathways by microarray-based expression profiling
-
Mullan PB, McWilliams S, Quinn J, Andrews H, Gilmore P, McCabe N, et al. Uncovering BRCA1-regulated signalling pathways by microarray-based expression profiling. Biochem Soc Trans 2001; 29:678-83.
-
(2001)
Biochem Soc Trans
, vol.29
, pp. 678-683
-
-
Mullan, P.B.1
McWilliams, S.2
Quinn, J.3
Andrews, H.4
Gilmore, P.5
McCabe, N.6
-
66
-
-
0032695277
-
Emerging roles of BRCA1 in transcriptional regulation and DNA repair
-
Chen Y, Lee W-H, Chew HK. Emerging roles of BRCA1 in transcriptional regulation and DNA repair. J Cell Physiol 1999; 181:385-92.
-
(1999)
J Cell Physiol
, vol.181
, pp. 385-392
-
-
Chen, Y.1
Lee, W.-H.2
Chew, H.K.3
-
67
-
-
0023649184
-
A new class of yeast transcriptional activators
-
Ma J, Ptashne M. A new class of yeast transcriptional activators. Cell 1987; 51:113-9.
-
(1987)
Cell
, vol.51
, pp. 113-119
-
-
Ma, J.1
Ptashne, M.2
-
68
-
-
0027218671
-
Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation
-
Roberts SG, Ha I, Maldonado E, Reinberg D, Green MR. Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation. Nature 1993; 363:741-4.
-
(1993)
Nature
, vol.363
, pp. 741-744
-
-
Roberts, S.G.1
Ha, I.2
Maldonado, E.3
Reinberg, D.4
Green, M.R.5
-
69
-
-
0033520396
-
Mutations that increase acidity enhance the transcriptional activity of the glutamine-rich activation domain in stage-specific activator protein
-
Benuck ML, Li Z, Childs G. Mutations that increase acidity enhance the transcriptional activity of the glutamine-rich activation domain in stage-specific activator protein. J Biol Chem 1999; 274:25419-25.
-
(1999)
J Biol Chem
, vol.274
, pp. 25419-25425
-
-
Benuck, M.L.1
Li, Z.2
Childs, G.3
-
70
-
-
0030833568
-
BRCA1 is a cell cycle-regulated nuclear phosphoprotein
-
USA
-
Ruffner H, Verma IM. BRCA1 is a cell cycle-regulated nuclear phosphoprotein. Proc Natl Acad Sci USA 1997; 94:7138-43.
-
(1997)
Proc Natl Acad Sci
, vol.94
, pp. 7138-7143
-
-
Ruffner, H.1
Verma, I.M.2
-
71
-
-
0032173668
-
Expression of BRCA1 and BRCA2 in normal and neoplastic cells
-
Chodosh LA. Expression of BRCA1 and BRCA2 in normal and neoplastic cells. J Mammary Gland Biol Neoplasia 1998; 3:389-402.
-
(1998)
J Mammary Gland Biol Neoplasia
, vol.3
, pp. 389-402
-
-
Chodosh, L.A.1
-
72
-
-
0029987651
-
BRCA1 is a 220-kDa nuclear phosphoprotein that is expressed and phosphorylated in a cell cycle-dependent manner
-
Chen Y, Farmer AA, Chen CF, Jones DC, Chen PL, Lee WH. BRCA1 is a 220-kDa nuclear phosphoprotein that is expressed and phosphorylated in a cell cycle-dependent manner. Cancer Res 1996; 56:3168-72.
-
(1996)
Cancer Res
, vol.56
, pp. 3168-3172
-
-
Chen, Y.1
Farmer, A.A.2
Chen, C.F.3
Jones, D.C.4
Chen, P.L.5
Lee, W.H.6
-
73
-
-
0029845485
-
Cell cycle regulation of BRCA1 messenger RNA in human breast epithelial cells
-
Gudas JM, Li T, Nguyen H, Jensen D, Rauscher IIIrd FJ, Cowan KH. Cell cycle regulation of BRCA1 messenger RNA in human breast epithelial cells. Cell Growth Differ 1996; 7:717-23.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 717-723
-
-
Gudas, J.M.1
Li, T.2
Nguyen, H.3
Jensen, D.4
Rauscher III, F.J.5
Cowan, K.H.6
-
74
-
-
0029822055
-
Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells
-
USA
-
Rajan JV, Wang M, Marquis ST, Chodosh LA. Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells. Proc Natl Acad Sci USA 1996; 93:13078-83.
-
(1996)
Proc Natl Acad Sci
, vol.93
, pp. 13078-13083
-
-
Rajan, J.V.1
Wang, M.2
Marquis, S.T.3
Chodosh, L.A.4
-
75
-
-
10244246652
-
BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells
-
Vaughn JP, Davis PL, Jarboe MD, Huper G, Evans AC, Wiseman RW, et al. BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells. Cell Growth Differ 1996; 7:711-5.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 711-715
-
-
Vaughn, J.P.1
Davis, P.L.2
Jarboe, M.D.3
Huper, G.4
Evans, A.C.5
Wiseman, R.W.6
-
76
-
-
0033805548
-
Tumor suppressor p53 is required to modulate BRCA1 expression
-
Arizti P, Fang L, Park I, Yin Y, Solomon E, Ouchi T, et al. Tumor suppressor p53 is required to modulate BRCA1 expression. Mol Cell Biol 2000; 20:7450-9.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 7450-7459
-
-
Arizti, P.1
Fang, L.2
Park, I.3
Yin, Y.4
Solomon, E.5
Ouchi, T.6
-
77
-
-
0034710541
-
Gene replacement with the human BRCA1 locus: Tissue specific expression and rescue of embryonic lethality in mice
-
Lane TF, Lin C, Brown MA, Solomon E, Leder P. Gene replacement with the human BRCA1 locus: Tissue specific expression and rescue of embryonic lethality in mice. Oncogene 2000; 19:4085-90.
-
(2000)
Oncogene
, vol.19
, pp. 4085-4090
-
-
Lane, T.F.1
Lin, C.2
Brown, M.A.3
Solomon, E.4
Leder, P.5
-
78
-
-
0035101934
-
Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice
-
Chandler J, Hohenstein P, Swing D, Tessarollo L, Sharan S. Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice. Genesis 2001; 29:72-7.
-
(2001)
Genesis
, vol.29
, pp. 72-77
-
-
Chandler, J.1
Hohenstein, P.2
Swing, D.3
Tessarollo, L.4
Sharan, S.5
-
80
-
-
0037046491
-
BRCA1 transactivates the cyclin-dependent kinase inhibitor p27Kip1
-
Williamson EA, Dadmanesh F, Koeffler HP. BRCA1 transactivates the cyclin-dependent kinase inhibitor p27Kip1. Oncogene 2002; 21:3199-206.
-
(2002)
Oncogene
, vol.21
, pp. 3199-3206
-
-
Williamson, E.A.1
Dadmanesh, F.2
Koeffler, H.P.3
-
81
-
-
0036261733
-
BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets
-
MacLachlan TK, Takimoto R, El-Deiry WS. BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets. Mol Cell Biol 2002; 22:4280-92.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4280-4292
-
-
MacLachlan, T.K.1
Takimoto, R.2
El-Deiry, W.S.3
-
82
-
-
0028828673
-
Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice
-
Lane TF, Deng CX, Elson A, Lyu MS, Kozak CA, Leder P. Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice. Genes Dev 1995; 9:2712-22.
-
(1995)
Genes Dev
, vol.9
, pp. 2712-2722
-
-
Lane, T.F.1
Deng, C.X.2
Elson, A.3
Lyu, M.S.4
Kozak, C.A.5
Leder, P.6
-
83
-
-
0029115660
-
The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissue
-
Marquis ST, Rajan JV, Wynshaw-Boris A, Xu J, Yin G-Y, Abel KJ, et al. The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissue. Nat Genet 1995; 11:17-20.
-
(1995)
Nat Genet
, vol.11
, pp. 17-20
-
-
Marquis, S.T.1
Rajan, J.V.2
Wynshaw-Boris, A.3
Xu, J.4
Yin, G.-Y.5
Abel, K.J.6
-
84
-
-
0032473879
-
BRCA1 physically associates with p53 and stimulates its transcriptional activity
-
Zhang H, Somasundaram K, Peng Y, Tian H, Bi D, Weber BL, et al. BRCA1 physically associates with p53 and stimulates its transcriptional activity. Oncogene 1998; 16:1713-21.
-
(1998)
Oncogene
, vol.16
, pp. 1713-1721
-
-
Zhang, H.1
Somasundaram, K.2
Peng, Y.3
Tian, H.4
Bi, D.5
Weber, B.L.6
-
85
-
-
0033547305
-
BRCA1 signals ARF-dependent stabilization and coactivation of p53
-
Somasundaram K, MacLachlan TK, Burns TF, Sgagias M, Cowan KH, Weber BL, et al. BRCA1 signals ARF-dependent stabilization and coactivation of p53. Oncogene 1999; 18:6605-14.
-
(1999)
Oncogene
, vol.18
, pp. 6605-6614
-
-
Somasundaram, K.1
MacLachlan, T.K.2
Burns, T.F.3
Sgagias, M.4
Cowan, K.H.5
Weber, B.L.6
-
86
-
-
0034723347
-
BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression
-
MacLachlan TK, Somasundaram K, Sgagias M, Shifman Y, Muschel RJ, Cowan KH, et al. BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression. J Biol Chem 2000; 275:2777-85.
-
(2000)
J Biol Chem
, vol.275
, pp. 2777-2785
-
-
MacLachlan, T.K.1
Somasundaram, K.2
Sgagias, M.3
Shifman, Y.4
Muschel, R.J.5
Cowan, K.H.6
-
87
-
-
0035854674
-
BRCA1 is a selective coactivator of 14-3-3CT gene transcription in mouse embryonic stem cells
-
Aprelikova O, Pace AJ, Fang B, Koller BH, Liu ET. BRCA1 is a selective coactivator of 14-3-3CT gene transcription in mouse embryonic stem cells. J Biol Chem 2001; 276:25647-50.
-
(2001)
J Biol Chem
, vol.276
, pp. 25647-25650
-
-
Aprelikova, O.1
Pace, A.J.2
Fang, B.3
Koller, B.H.4
Liu, E.T.5
-
88
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
Paull TT, Rogakou EP, Yamazaki V, Kirchgessner CU, Gellert M, Bonner WM. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Current Biology 2000; 10:886-95.
-
(2000)
Current Biology
, vol.10
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
89
-
-
0038296998
-
Impaired meiotic DNA-damage repair and lack of crossing-over during spermatogenesis in BRCA1 full-length isoform deficient mice
-
Xu X, Aprelikova O, Moens P, Deng CX, Furth PA. Impaired meiotic DNA-damage repair and lack of crossing-over during spermatogenesis in BRCA1 full-length isoform deficient mice. Development 2003; 130:2001-12.
-
(2003)
Development
, vol.130
, pp. 2001-2012
-
-
Xu, X.1
Aprelikova, O.2
Moens, P.3
Deng, C.X.4
Furth, P.A.5
-
90
-
-
0036500555
-
Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage
-
Kim ST, Xu B, Kastan MB. Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. Genes Dev 2002; 16:560-70.
-
(2002)
Genes Dev
, vol.16
, pp. 560-570
-
-
Kim, S.T.1
Xu, B.2
Kastan, M.B.3
-
91
-
-
0346101743
-
Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains
-
Rodriguez M, Yu X, Chen J, Songyang Z. Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains. J Biol Chem 2003; 278:52914-8.
-
(2003)
J Biol Chem
, vol.278
, pp. 52914-52918
-
-
Rodriguez, M.1
Yu, X.2
Chen, J.3
Songyang, Z.4
-
92
-
-
0142240342
-
BRCT repeats as phosphopeptide-binding modules involved in protein targeting
-
Manke IA, Lowery DM, Nguyen A, Yaffe MB. BRCT repeats as phosphopeptide-binding modules involved in protein targeting. Science 2003; 302:636-9.
-
(2003)
Science
, vol.302
, pp. 636-639
-
-
Manke, I.A.1
Lowery, D.M.2
Nguyen, A.3
Yaffe, M.B.4
-
93
-
-
0142147272
-
The BRCT domain is a phospho-protein binding domain
-
Yu X, Chini CC, He M, Mer G, Chen J. The BRCT domain is a phospho-protein binding domain. Science 2003; 302:639-42.
-
(2003)
Science
, vol.302
, pp. 639-642
-
-
Yu, X.1
Chini, C.C.2
He, M.3
Mer, G.4
Chen, J.5
-
94
-
-
2542489188
-
Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer
-
Clapperton JA, Manke IA, Lowery DM, Ho T, Haire LF, Yaffe MB, et al. Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer. Nat Struct Mol Biol 2004; 11:512-8.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 512-518
-
-
Clapperton, J.A.1
Manke, I.A.2
Lowery, D.M.3
Ho, T.4
Haire, L.F.5
Yaffe, M.B.6
-
95
-
-
0035032649
-
2-phase checkpoints after ionizing irradiation
-
2-phase checkpoints after ionizing irradiation. Mol Cell Biol 2001; 21:3445-50.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3445-3450
-
-
Xu, B.1
Kim, S.2
Kastan, M.B.3
-
97
-
-
0033601346
-
Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome
-
Bell DW, Varley JM, Szydlo TE, Kang DH, Wahrer DCR, Shannon KE, et al. Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome. Science 1999; 286:2528-31.
-
(1999)
Science
, vol.286
, pp. 2528-2531
-
-
Bell, D.W.1
Varley, J.M.2
Szydlo, T.E.3
Kang, D.H.4
Wahrer, D.C.R.5
Shannon, K.E.6
-
98
-
-
18544389716
-
Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations
-
Meijers-Heijboer H, van den Ouweland A, Klijn J, Wasielewski M, de Snoo A, Oldenburg R, et al. Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations. Nat Genet 2002; 31:55-9.
-
(2002)
Nat Genet
, vol.31
, pp. 55-59
-
-
Meijers-Heijboer, H.1
Van Den Ouweland, A.2
Klijn, J.3
Wasielewski, M.4
De Snoo, A.5
Oldenburg, R.6
|