메뉴 건너뛰기




Volumn 73, Issue 7, 2005, Pages 3833-3841

Worms and flies as genetically tractable animal models to study host-pathogen interactions

Author keywords

[No Author keywords available]

Indexed keywords

VIRULENCE FACTOR;

EID: 21544439035     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.73.7.3833-3841.2005     Document Type: Short Survey
Times cited : (107)

References (86)
  • 1
    • 0036164933 scopus 로고    scopus 로고
    • Caenorhabditis elegans as a host for the study of host-pathogen interactions
    • Aballay, A., and F. M. Ausubel. 2002. Caenorhabditis elegans as a host for the study of host-pathogen interactions. Curr. Opin. Microbiol. 5:97-101.
    • (2002) Curr. Opin. Microbiol. , vol.5 , pp. 97-101
    • Aballay, A.1    Ausubel, F.M.2
  • 2
    • 0035956931 scopus 로고    scopus 로고
    • Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing
    • Aballay, A., and F. M. Ausubel. 2001. Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing. Proc. Natl. Acad. Sci. USA 98:2735-2739.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 2735-2739
    • Aballay, A.1    Ausubel, F.M.2
  • 3
    • 0037425599 scopus 로고    scopus 로고
    • Caenorhabditis elegans innate immune response triggered by Salmonella enterica requires intact LPS and is mediated by a MAPK signaling pathway
    • Aballay, A., E. Drenkard, L. R. Hilbun, and F. M. Ausubel. 2003. Caenorhabditis elegans innate immune response triggered by Salmonella enterica requires intact LPS and is mediated by a MAPK signaling pathway. Curr. Biol. 13:47-52.
    • (2003) Curr. Biol. , vol.13 , pp. 47-52
    • Aballay, A.1    Drenkard, E.2    Hilbun, L.R.3    Ausubel, F.M.4
  • 4
    • 0034735919 scopus 로고    scopus 로고
    • Salmonella typhimurium proliferates and establishes a persistent infection in the intestine of Caenorhabditis elegans
    • Aballay, A., P. Yorgey, and F. M. Ausubel. 2000. Salmonella typhimurium proliferates and establishes a persistent infection in the intestine of Caenorhabditis elegans. Curr. Biol. 10:1539-1542.
    • (2000) Curr. Biol. , vol.10 , pp. 1539-1542
    • Aballay, A.1    Yorgey, P.2    Ausubel, F.M.3
  • 5
    • 0038725947 scopus 로고    scopus 로고
    • Characterization of mediators of microbial virulence and innate immunity using the Caenorhabditis elegans host-pathogen model
    • Alegado, R. A., M. C. Campbell, W. C. Chen, S. S. Slutz, and M. W. Tan. 2003. Characterization of mediators of microbial virulence and innate immunity using the Caenorhabditis elegans host-pathogen model. Cell. Microbiol. 5:435-444.
    • (2003) Cell. Microbiol. , vol.5 , pp. 435-444
    • Alegado, R.A.1    Campbell, M.C.2    Chen, W.C.3    Slutz, S.S.4    Tan, M.W.5
  • 6
    • 14044277610 scopus 로고    scopus 로고
    • Profiling early infection responses: Pseudomonas aeruginosa eludes host defenses by suppressing antimicrobial peptide gene expression
    • Apidianakis, Y., M. N. Mindrinos, W. Xiao, G. W. Lau, R. L. Baldini, R. W. Davis, and L. G. Rahme. 2005. Profiling early infection responses: Pseudomonas aeruginosa eludes host defenses by suppressing antimicrobial peptide gene expression. Proc. Natl. Acad. Sci. USA 102:2573-2578.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 2573-2578
    • Apidianakis, Y.1    Mindrinos, M.N.2    Xiao, W.3    Lau, G.W.4    Baldini, R.L.5    Davis, R.W.6    Rahme, L.G.7
  • 7
    • 3342963000 scopus 로고    scopus 로고
    • Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response
    • Apidianakis, Y., L. G. Rahme, J. Heitman, F. M. Ausubel, S. B. Calderwood, and E. Mylonakis. 2004. Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response. Eukaryot. Cell 3:413-419.
    • (2004) Eukaryot. Cell , vol.3 , pp. 413-419
    • Apidianakis, Y.1    Rahme, L.G.2    Heitman, J.3    Ausubel, F.M.4    Calderwood, S.B.5    Mylonakis, E.6
  • 9
    • 0038242875 scopus 로고    scopus 로고
    • Toll-like receptor signaling pathways
    • Barton, G. M., and R. Medzhitov. 2003. Toll-like receptor signaling pathways. Science 300:1524-1525.
    • (2003) Science , vol.300 , pp. 1524-1525
    • Barton, G.M.1    Medzhitov, R.2
  • 10
    • 0023969046 scopus 로고
    • The plasmid-encoded Yop2b protein of Yersinia pseudotuberculosis is a virulence determinant regulated by calcium and temperature at the level of transcription
    • Bolin, I., and H. Wolf-Watz. 1988. The plasmid-encoded Yop2b protein of Yersinia pseudotuberculosis is a virulence determinant regulated by calcium and temperature at the level of transcription. Mol. Microbiol. 2:237-245.
    • (1988) Mol. Microbiol. , vol.2 , pp. 237-245
    • Bolin, I.1    Wolf-Watz, H.2
  • 11
    • 0015524896 scopus 로고
    • Inducible antibacterial defense system in Drosophila
    • Boman, H. G., I. Nilsson, and B. Rasmuson. 1972. Inducible antibacterial defense system in Drosophila. Nature 237:232-235.
    • (1972) Nature , vol.237 , pp. 232-235
    • Boman, H.G.1    Nilsson, I.2    Rasmuson, B.3
  • 12
    • 0036848010 scopus 로고    scopus 로고
    • Sequential activation of signaling pathways during innate immune responses in Drosophila
    • Boutros, M., H. Agaisse, and N. Perrimon. 2002. Sequential activation of signaling pathways during innate immune responses in Drosophila. Dev. Cell 3:711-722.
    • (2002) Dev. Cell , vol.3 , pp. 711-722
    • Boutros, M.1    Agaisse, H.2    Perrimon, N.3
  • 13
    • 14044261186 scopus 로고    scopus 로고
    • Secreted bacterial effectors and host-produced Eiger/TNF drive death in a Salmonella-infected fruit fly
    • Brandt, S. M., M. S. Dionne, R. S. Khush, L. N. Pham, T. J. Vigdal, and D. S. Schneider. 2004. Secreted bacterial effectors and host-produced Eiger/TNF drive death in a Salmonella-infected fruit fly. PLoS Biol. 2:e418.
    • (2004) PLoS Biol. , vol.2
    • Brandt, S.M.1    Dionne, M.S.2    Khush, R.S.3    Pham, L.N.4    Vigdal, T.J.5    Schneider, D.S.6
  • 14
    • 2442715852 scopus 로고    scopus 로고
    • Drosophila: The genetics of innate immune recognition and response
    • Brennan, C. A., and K. V. Anderson. 2004. Drosophila: the genetics of innate immune recognition and response. Annu. Rev. Immunol. 22:457-483.
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 457-483
    • Brennan, C.A.1    Anderson, K.V.2
  • 15
    • 0346728473 scopus 로고    scopus 로고
    • Systematic genome-wide screens of gene function
    • Carpenter, A. E., and D. M. Sabatini. 2004. Systematic genome-wide screens of gene function. Nat. Rev. Genet. 5:11-22.
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 11-22
    • Carpenter, A.E.1    Sabatini, D.M.2
  • 16
    • 0037066464 scopus 로고    scopus 로고
    • Requirement for a peptidoglycan recognition protein (PGRP) in Relish activation and antibacterial immune responses in Drosophila
    • Choe, K. M., T. Werner, S. Stoven, D. Hultmark, and K. V. Anderson. 2002. Requirement for a peptidoglycan recognition protein (PGRP) in Relish activation and antibacterial immune responses in Drosophila. Science 296:359-362.
    • (2002) Science , vol.296 , pp. 359-362
    • Choe, K.M.1    Werner, T.2    Stoven, S.3    Hultmark, D.4    Anderson, K.V.5
  • 17
    • 0029926724 scopus 로고    scopus 로고
    • Characterization of an immunodeficiency mutant in Drosophila
    • Corbo, J. C., and M. Levine. 1996. Characterization of an immunodeficiency mutant in Drosophila. Mech. Dev. 55:211-220.
    • (1996) Mech. Dev. , vol.55 , pp. 211-220
    • Corbo, J.C.1    Levine, M.2
  • 18
    • 2442664007 scopus 로고    scopus 로고
    • TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM
    • Couillault, C., N. Pujol, J. Reboul, L. Sabatier, J. F. Guichou, Y. Kohara, and J. J. Ewbank. 2004. TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Nat. Immunol. 5:488-494.
    • (2004) Nat. Immunol. , vol.5 , pp. 488-494
    • Couillault, C.1    Pujol, N.2    Reboul, J.3    Sabatier, L.4    Guichou, J.F.5    Kohara, Y.6    Ewbank, J.J.7
  • 19
    • 0034833062 scopus 로고    scopus 로고
    • Mimicry of a G protein mutation by pertussis toxin expression in transgenic Caenorhabditis elegans
    • Darby, C., and S. Falkow. 2001. Mimicry of a G protein mutation by pertussis toxin expression in transgenic Caenorhabditis elegans. Infect. Immun. 69:6271-6275.
    • (2001) Infect. Immun. , vol.69 , pp. 6271-6275
    • Darby, C.1    Falkow, S.2
  • 20
    • 0035140125 scopus 로고    scopus 로고
    • Drosophila as a model host for Pseudomonas aeruginosa infection
    • D'Argenio, D. A., L. A. Gallagher, C. A. Berg, and C. Manoil. 2001. Drosophila as a model host for Pseudomonas aeruginosa infection. J. Bacteriol. 183:1466-1471.
    • (2001) J. Bacteriol. , vol.183 , pp. 1466-1471
    • D'Argenio, D.A.1    Gallagher, L.A.2    Berg, C.A.3    Manoil, C.4
  • 21
    • 0035940514 scopus 로고    scopus 로고
    • Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays
    • De Gregorio, E., P. T. Spellman, G. M. Rubin, and B. Lemaitre. 2001. Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays. Proc. Natl. Acad. Sci. USA 98:12590-12595.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 12590-12595
    • De Gregorio, E.1    Spellman, P.T.2    Rubin, G.M.3    Lemaitre, B.4
  • 22
    • 0037013856 scopus 로고    scopus 로고
    • The Toll and Imd pathways are the major regulators of the immune response in Drosophila
    • De Gregorio, E., P. T. Spellman, P. Tzou, G. M. Rubin, and B. Lemaitre. 2002. The Toll and Imd pathways are the major regulators of the immune response in Drosophila. EMBO J. 21:2568-2579.
    • (2002) EMBO J. , vol.21 , pp. 2568-2579
    • De Gregorio, E.1    Spellman, P.T.2    Tzou, P.3    Rubin, G.M.4    Lemaitre, B.5
  • 23
    • 19344370696 scopus 로고    scopus 로고
    • Functional dissection of an innate immune response by a genome-wide RNAi screen
    • Foley, E., and P. H. O'Farrell. 2004. Functional dissection of an innate immune response by a genome-wide RNAi screen. PLoS Biol. 2:E203.
    • (2004) PLoS Biol. , vol.2
    • Foley, E.1    O'Farrell, P.H.2
  • 24
    • 0025218678 scopus 로고
    • Genetic analysis of the yopE region of Yersinia spp.: Identification of a novel conserved locus, yerA, regulating yopE expression
    • Forsberg, A., and H. Wolf-Watz. 1990. Genetic analysis of the yopE region of Yersinia spp.: identification of a novel conserved locus, yerA, regulating yopE expression. J. Bacteriol. 172:1547-1555.
    • (1990) J. Bacteriol. , vol.172 , pp. 1547-1555
    • Forsberg, A.1    Wolf-Watz, H.2
  • 25
    • 0033575956 scopus 로고    scopus 로고
    • A Salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion
    • Fu, Y., and J. E. Galan. 1999. A Salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion. Nature 401:293-297.
    • (1999) Nature , vol.401 , pp. 293-297
    • Fu, Y.1    Galan, J.E.2
  • 26
    • 0035685108 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa PAO1 kills Caenorhabditis elegans by cyanide poisoning
    • Gallagher, L. A., and C. Manoil. 2001. Pseudomonas aeruginosa PAO1 kills Caenorhabditis elegans by cyanide poisoning. J. Bacteriol. 183:6207-6214.
    • (2001) J. Bacteriol. , vol.183 , pp. 6207-6214
    • Gallagher, L.A.1    Manoil, C.2
  • 27
    • 0036015636 scopus 로고    scopus 로고
    • Characterization of Burkholderia pseudomallei infection and identification of novel virulence factors using a Caenorhabditis elegans host system
    • Gan, Y. H., K. L. Chua, H. H. Chua, B. Liu, C. S. Hii, H. L. Chong, and P. Tan. 2002. Characterization of Burkholderia pseudomallei infection and identification of novel virulence factors using a Caenorhabditis elegans host system. Mol. Microbiol. 44:1185-1197.
    • (2002) Mol. Microbiol. , vol.44 , pp. 1185-1197
    • Gan, Y.H.1    Chua, K.L.2    Chua, H.H.3    Liu, B.4    Hii, C.S.5    Chong, H.L.6    Tan, P.7
  • 30
    • 0037061450 scopus 로고    scopus 로고
    • The Drosophila immune response against gram-negative bacteria is mediated by a peptidoglycan recognition protein
    • Gottar, M., V. Gobert, T. Michel, M. Belvin, G. Duyk, J. A. Hoffmann, D. Ferrandon, and J. Royet. 2002. The Drosophila immune response against gram-negative bacteria is mediated by a peptidoglycan recognition protein. Nature 416:640-644.
    • (2002) Nature , vol.416 , pp. 640-644
    • Gottar, M.1    Gobert, V.2    Michel, T.3    Belvin, M.4    Duyk, G.5    Hoffmann, J.A.6    Ferrandon, D.7    Royet, J.8
  • 32
    • 0035800468 scopus 로고    scopus 로고
    • Bt toxin resistance from loss of a putative carbohydrate-modifying enzyme
    • Griffitts, J. S., J. L. Whitacre, D. E. Stevens, and R. V. Aroian. 2001. Bt toxin resistance from loss of a putative carbohydrate-modifying enzyme. Science 293:860-864.
    • (2001) Science , vol.293 , pp. 860-864
    • Griffitts, J.S.1    Whitacre, J.L.2    Stevens, D.E.3    Aroian, R.V.4
  • 33
    • 0037567359 scopus 로고    scopus 로고
    • Yeast, flies, worms, and fish in the study of human disease
    • Hariharan, I. K., and D. A. Haber. 2003. Yeast, flies, worms, and fish in the study of human disease. N. Engl. J. Med. 348:2457-2463.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 2457-2463
    • Hariharan, I.K.1    Haber, D.A.2
  • 34
    • 0034649644 scopus 로고    scopus 로고
    • A novel bacterial pathogen, Microbacterium nematophilum, induces morphological change in the nematode C. elegans
    • Hodgkin, J., P. E. Kuwabara, and B. Corneliussen. 2000. A novel bacterial pathogen, Microbacterium nematophilum, induces morphological change in the nematode C. elegans. Curr. Biol. 10:1615-1618.
    • (2000) Curr. Biol. , vol.10 , pp. 1615-1618
    • Hodgkin, J.1    Kuwabara, P.E.2    Corneliussen, B.3
  • 35
    • 0242581687 scopus 로고    scopus 로고
    • The immune response of Drosophila
    • Hoffmann, J. A. 2003. The immune response of Drosophila. Nature 426:33-38.
    • (2003) Nature , vol.426 , pp. 33-38
    • Hoffmann, J.A.1
  • 36
    • 0036167107 scopus 로고    scopus 로고
    • Drosophila innate immunity: An evolutionary perspective
    • Hoffmann, J. A., and J. M. Reichhart. 2002. Drosophila innate immunity: an evolutionary perspective. Nat. Immunol. 3:121-126.
    • (2002) Nat. Immunol. , vol.3 , pp. 121-126
    • Hoffmann, J.A.1    Reichhart, J.M.2
  • 37
    • 9244243106 scopus 로고    scopus 로고
    • Identification of a novel virulence factor in Burkholderia cenocepacia H111 required for efficient slow killing of Caenorhabditis elegans
    • Huber, B., F. Feldmann, M. Kothe, P. Vandamme, J. Wopperer, K. Riedel, and L. Eberl. 2004. Identification of a novel virulence factor in Burkholderia cenocepacia H111 required for efficient slow killing of Caenorhabditis elegans. Infect. Immun. 72:7220-7230.
    • (2004) Infect. Immun. , vol.72 , pp. 7220-7230
    • Huber, B.1    Feldmann, F.2    Kothe, M.3    Vandamme, P.4    Wopperer, J.5    Riedel, K.6    Eberl, L.7
  • 41
    • 0036718479 scopus 로고    scopus 로고
    • Hydrogen peroxide-mediated killing of Caenorhabditis elegans by Streptococcus pyogenes
    • Jansen, W. T., M. Bolm, R. Balling, G. S. Chhatwal, and R. Schnabel. 2002. Hydrogen peroxide-mediated killing of Caenorhabditis elegans by Streptococcus pyogenes. Infect. Immun. 70:5202-5207.
    • (2002) Infect. Immun. , vol.70 , pp. 5202-5207
    • Jansen, W.T.1    Bolm, M.2    Balling, R.3    Chhatwal, G.S.4    Schnabel, R.5
  • 42
    • 0142031430 scopus 로고    scopus 로고
    • Role of Toll-like receptors in pathogen recognition
    • Janssens, S., and R. Beyaert. 2003. Role of Toll-like receptors in pathogen recognition. Clin. Microbiol. Rev. 16:637-646.
    • (2003) Clin. Microbiol. Rev. , vol.16 , pp. 637-646
    • Janssens, S.1    Beyaert, R.2
  • 43
    • 0344443216 scopus 로고    scopus 로고
    • A Caenorhabditis elegans model of Yersinia infection: Biofilm formation on a biotic surface
    • Joshua, G. W., A. V. Karlyshev, M. P. Smith, K. E. Isherwood, R. W. Titball, and B. W. Wren. 2003. A Caenorhabditis elegans model of Yersinia infection: biofilm formation on a biotic surface. Microbiology 149:3221-3229.
    • (2003) Microbiology , vol.149 , pp. 3221-3229
    • Joshua, G.W.1    Karlyshev, A.V.2    Smith, M.P.3    Isherwood, K.E.4    Titball, R.W.5    Wren, B.W.6
  • 44
    • 0029839017 scopus 로고    scopus 로고
    • A secreted protein tyrosine phosphatase with modular effector domains in the bacterial pathogen Salmonella typhimurium
    • Kaniga, K., J. Uralil, J. B. Bliska, and J. E. Galan. 1996. A secreted protein tyrosine phosphatase with modular effector domains in the bacterial pathogen Salmonella typhimurium. Mol. Microbiol. 21:633-641.
    • (1996) Mol. Microbiol. , vol.21 , pp. 633-641
    • Kaniga, K.1    Uralil, J.2    Bliska, J.B.3    Galan, J.E.4
  • 47
    • 13644264408 scopus 로고    scopus 로고
    • Regulation of aging and innate immunity in C. elegans
    • Kurz, C. L., and M. W. Tan. 2004. Regulation of aging and innate immunity in C. elegans. Aging Cell 3:185-193.
    • (2004) Aging Cell , vol.3 , pp. 185-193
    • Kurz, C.L.1    Tan, M.W.2
  • 48
  • 50
    • 1642422755 scopus 로고    scopus 로고
    • The immune response of Drosophila melanogaster
    • Leclerc, V., and J. M. Reichhart. 2004. The immune response of Drosophila melanogaster. Immunol. Rev. 198:59-71.
    • (2004) Immunol. Rev. , vol.198 , pp. 59-71
    • Leclerc, V.1    Reichhart, J.M.2
  • 51
    • 0035846601 scopus 로고    scopus 로고
    • Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway
    • Lee, R. Y., J. Hench, and G. Ruvkun. 2001. Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway. Curr. Biol. 11:1950-1957.
    • (2001) Curr. Biol. , vol.11 , pp. 1950-1957
    • Lee, R.Y.1    Hench, J.2    Ruvkun, G.3
  • 53
    • 0028877993 scopus 로고
    • Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila
    • Lemaitre, B., M. Meister, S. Govind, P. Georgel, R. Steward, J. M. Reichhart, and J. A. Hoffmann. 1995. Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila. EMBO J. 14:536-545.
    • (1995) EMBO J. , vol.14 , pp. 536-545
    • Lemaitre, B.1    Meister, M.2    Govind, S.3    Georgel, P.4    Steward, R.5    Reichhart, J.M.6    Hoffmann, J.A.7
  • 54
    • 0030595339 scopus 로고    scopus 로고
    • The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • Lemaitre, B., E. Nicolas, L. Michaut, J. M. Reichhart, and J. A. Hoffmann. 1996. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86:973-983.
    • (1996) Cell , vol.86 , pp. 973-983
    • Lemaitre, B.1    Nicolas, E.2    Michaut, L.3    Reichhart, J.M.4    Hoffmann, J.A.5
  • 55
    • 0031446642 scopus 로고    scopus 로고
    • Drosophila host defense: Differential induction of antimicrobial peptide genes after infection by various classes of microorganisms
    • Lemaitre, B., J. M. Reichhart, and J. A. Hoffmann. 1997. Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. Proc. Natl. Acad. Sci. USA 94:14614-14619.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14614-14619
    • Lemaitre, B.1    Reichhart, J.M.2    Hoffmann, J.A.3
  • 56
    • 2342475724 scopus 로고    scopus 로고
    • Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response
    • Liberati, N. T., K. A. Fitzgerald, D. H. Kim, R. Feinbaum, D. T. Golenbock, and F. M. Ausubel. 2004. Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response. Proc. Natl. Acad. Sci. USA 101:6593-6598.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 6593-6598
    • Liberati, N.T.1    Fitzgerald, K.A.2    Kim, D.H.3    Feinbaum, R.4    Golenbock, D.T.5    Ausubel, F.M.6
  • 57
    • 0030657540 scopus 로고    scopus 로고
    • Daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
    • Lin, K., J. B. Dorman, A. Rodan, and C. Kenyon. 1997. daf-16: an HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278:1319-1322.
    • (1997) Science , vol.278 , pp. 1319-1322
    • Lin, K.1    Dorman, J.B.2    Rodan, A.3    Kenyon, C.4
  • 58
    • 0033534534 scopus 로고    scopus 로고
    • Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa-Caenorhabditis elegans pathogenesis model
    • Mahajan-Miklos, S., M. W. Tan, L. G. Rahme, and F. M. Ausubel. 1999. Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa-Caenorhabditis elegans pathogenesis model. Cell 96:47-56.
    • (1999) Cell , vol.96 , pp. 47-56
    • Mahajan-Miklos, S.1    Tan, M.W.2    Rahme, L.G.3    Ausubel, F.M.4
  • 60
    • 0033886109 scopus 로고    scopus 로고
    • Bacillus thuringiensis (Bt) toxin susceptibility and isolation of resistance mutants in the nematode Caenorhabditis elegans
    • Marroquin, L. D., D. Elyassnia, J. S. Griffitts, J. S. Feitelson, and R. V. Aroian. 2000. Bacillus thuringiensis (Bt) toxin susceptibility and isolation of resistance mutants in the nematode Caenorhabditis elegans. Genetics 155:1693-1699.
    • (2000) Genetics , vol.155 , pp. 1693-1699
    • Marroquin, L.D.1    Elyassnia, D.2    Griffitts, J.S.3    Feitelson, J.S.4    Aroian, R.V.5
  • 62
    • 0024216207 scopus 로고
    • Nucleotide sequence and transcription analysis of yop51 from Yersinia enterocolitica W22703
    • Michiels, T., and G. Cornelis. 1988. Nucleotide sequence and transcription analysis of yop51 from Yersinia enterocolitica W22703. Microb. Pathog. 5:449-459.
    • (1988) Microb. Pathog. , vol.5 , pp. 449-459
    • Michiels, T.1    Cornelis, G.2
  • 64
    • 3342891121 scopus 로고    scopus 로고
    • Cytotoxicity of hydrogen peroxide produced by Enterococcus faecium
    • Moy, T. I., E. Mylonakis, S. B. Calderwood, and F. M. Ausubel. 2004. Cytotoxicity of hydrogen peroxide produced by Enterococcus faecium. Infect. Immun. 72:4512-4520.
    • (2004) Infect. Immun. , vol.72 , pp. 4512-4520
    • Moy, T.I.1    Mylonakis, E.2    Calderwood, S.B.3    Ausubel, F.M.4
  • 66
  • 67
    • 6344275552 scopus 로고    scopus 로고
    • Cryptococcus neoformans Kin1 protein kinase homologue, identified through a Caenorhabditis elegans screen, promotes virulence in mammals
    • Mylonakis, E., A. Idnurm, R. Moreno, J. El Khoury, J. B. Rottman, F. M. Ausubel, J. Heitman, and S. B. Calderwood. 2004. Cryptococcus neoformans Kin1 protein kinase homologue, identified through a Caenorhabditis elegans screen, promotes virulence in mammals. Mol. Microbiol. 54:407-419.
    • (2004) Mol. Microbiol. , vol.54 , pp. 407-419
    • Mylonakis, E.1    Idnurm, A.2    Moreno, R.3    El Khoury, J.4    Rottman, J.B.5    Ausubel, F.M.6    Heitman, J.7    Calderwood, S.B.8
  • 68
    • 3342973834 scopus 로고    scopus 로고
    • The ERK MAP kinase cascade mediates tail swelling and a protective response to rectal infection in C. elegans
    • Nicholas, H. R., and J. Hodgkin. 2004. The ERK MAP kinase cascade mediates tail swelling and a protective response to rectal infection in C. elegans. Curr. Biol. 14:1256-1261.
    • (2004) Curr. Biol. , vol.14 , pp. 1256-1261
    • Nicholas, H.R.1    Hodgkin, J.2
  • 69
    • 2942562261 scopus 로고    scopus 로고
    • Responses to infection and possible recognition strategies in the innate immune system of Caenorhabditis elegans
    • Nicholas, H. R., and J. Hodgkin. 2004. Responses to infection and possible recognition strategies in the innate immune system of Caenorhabditis elegans. Mol. Immunol. 41:479-493.
    • (2004) Mol. Immunol. , vol.41 , pp. 479-493
    • Nicholas, H.R.1    Hodgkin, J.2
  • 70
    • 0030659557 scopus 로고    scopus 로고
    • The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
    • Ogg, S., S. Paradis, S. Gottlieb, G. I. Patterson, L. Lee, H. A. Tissenbaum, and G. Ruvkun. 1997. The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389:994-999.
    • (1997) Nature , vol.389 , pp. 994-999
    • Ogg, S.1    Paradis, S.2    Gottlieb, S.3    Patterson, G.I.4    Lee, L.5    Tissenbaum, H.A.6    Ruvkun, G.7
  • 71
    • 0034960639 scopus 로고    scopus 로고
    • Burkholderia pseudomallei kills the nematode Caenorhabditis elegans using an endotoxin-mediated paralysis
    • O'Quinn, A. L., E. M. Wiegand, and J. A. Jeddeloh. 2001. Burkholderia pseudomallei kills the nematode Caenorhabditis elegans using an endotoxin-mediated paralysis. Cell. Microbiol. 3:381-393.
    • (2001) Cell. Microbiol. , vol.3 , pp. 381-393
    • O'Quinn, A.L.1    Wiegand, E.M.2    Jeddeloh, J.A.3
  • 74
    • 0141835132 scopus 로고    scopus 로고
    • Toll-like receptors and their role in experimental models of microbial infection
    • Qureshi, S. T., and R. Medzhitov. 2003. Toll-like receptors and their role in experimental models of microbial infection. Genes Immun. 4:87-94.
    • (2003) Genes Immun. , vol.4 , pp. 87-94
    • Qureshi, S.T.1    Medzhitov, R.2
  • 75
    • 0037061482 scopus 로고    scopus 로고
    • Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli
    • Ramet, M., P. Manfruelli, A. Pearson, B. Mathey-Prevot, and R. A. Ezekowitz. 2002. Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. Nature 416:644-648.
    • (2002) Nature , vol.416 , pp. 644-648
    • Ramet, M.1    Manfruelli, P.2    Pearson, A.3    Mathey-Prevot, B.4    Ezekowitz, R.A.5
  • 76
    • 0027368433 scopus 로고
    • Expression and nuclear translocation of the rel/NF-kappa B-related morphogen dorsal during the immune response of Drosophila
    • Reichhart, J. M., P. Georgel, M. Meister, B. Lemaitre, C. Kappler, and J. A. Hoffmann. 1993. Expression and nuclear translocation of the rel/NF-kappa B-related morphogen dorsal during the immune response of Drosophila. C. R. Acad. Sci. Ser. III 316:1218-1224.
    • (1993) C. R. Acad. Sci. Ser. III , vol.316 , pp. 1218-1224
    • Reichhart, J.M.1    Georgel, P.2    Meister, M.3    Lemaitre, B.4    Kappler, C.5    Hoffmann, J.A.6
  • 78
    • 1642463846 scopus 로고    scopus 로고
    • Evolution of the innate immune system: The worm perspective
    • Schulenburg, H., C. L. Kurz, and J. J. Ewbank. 2004. Evolution of the innate immune system: the worm perspective. Immunol. Rev. 198:36-58.
    • (2004) Immunol. Rev. , vol.198 , pp. 36-58
    • Schulenburg, H.1    Kurz, C.L.2    Ewbank, J.J.3
  • 79
    • 11844251384 scopus 로고    scopus 로고
    • The worm has turned-microbial virulence modeled in Caenorhabditis elegans
    • Sifri, C. D., J. Begun, and F. M. Ausubel. 2005. The worm has turned-microbial virulence modeled in Caenorhabditis elegans. Trends Microbiol. 13:119-127.
    • (2005) Trends Microbiol. , vol.13 , pp. 119-127
    • Sifri, C.D.1    Begun, J.2    Ausubel, F.M.3
  • 80
    • 0037347050 scopus 로고    scopus 로고
    • Toll receptors and pathogen resistance
    • Takeda, K., and S. Akira. 2003. Toll receptors and pathogen resistance. Cell. Microbiol. 5:143-153.
    • (2003) Cell. Microbiol. , vol.5 , pp. 143-153
    • Takeda, K.1    Akira, S.2
  • 81
    • 0033582314 scopus 로고    scopus 로고
    • Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis
    • Tan, M. W., S. Mahajan-Miklos, and F. M. Ausubel. 1999. Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis. Proc. Natl. Acad. Sci. USA 96:715-720.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 715-720
    • Tan, M.W.1    Mahajan-Miklos, S.2    Ausubel, F.M.3
  • 82
    • 0033515018 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors
    • Tan, M. W., L. G. Rahme, J. A. Sternberg, R. G. Tompkins, and F. M. Ausubel. 1999. Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors. Proc. Natl. Acad. Sci. USA 96:2408-2413.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 2408-2413
    • Tan, M.W.1    Rahme, L.G.2    Sternberg, J.A.3    Tompkins, R.G.4    Ausubel, F.M.5
  • 84
    • 2642576778 scopus 로고    scopus 로고
    • Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions
    • Tenor, J. L., B. A. McCormick, F. M. Ausubel, and A. Aballay. 2004. Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions. Curr. Biol. 14:1018-1024.
    • (2004) Curr. Biol. , vol.14 , pp. 1018-1024
    • Tenor, J.L.1    McCormick, B.A.2    Ausubel, F.M.3    Aballay, A.4
  • 85
    • 0036160153 scopus 로고    scopus 로고
    • How Drosophila combats microbial infection: A model to study innate immunity and host-pathogen interactions
    • Tzou, P., E. De Gregorio, and B. Lemaitre. 2002. How Drosophila combats microbial infection: a model to study innate immunity and host-pathogen interactions. Curr. Opin. Microbiol. 5:102-110.
    • (2002) Curr. Opin. Microbiol. , vol.5 , pp. 102-110
    • Tzou, P.1    De Gregorio, E.2    Lemaitre, B.3
  • 86
    • 0032485392 scopus 로고    scopus 로고
    • Regulated nuclear import of Rel proteins in the Drosophila immune response
    • Wu, L. P., and K. V. Anderson. 1998. Regulated nuclear import of Rel proteins in the Drosophila immune response. Nature 392:93-97.
    • (1998) Nature , vol.392 , pp. 93-97
    • Wu, L.P.1    Anderson, K.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.