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Volumn 54, Issue 2, 2004, Pages 407-419

Cryptococcus neoformans Kin1 protein kinase homologue, identified through a Caenorhabditis elegans screen, promotes virulence in mammals

Author keywords

[No Author keywords available]

Indexed keywords

KIN1 PROTEIN KINASE; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

EID: 6344275552     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2004.04310.x     Document Type: Article
Times cited : (61)

References (46)
  • 1
    • 0030668723 scopus 로고    scopus 로고
    • Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP
    • Alspaugh, J.A., Perfect, J.R., and Heitman, J. (1997) Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP. Genes Dev 11: 3206-3217.
    • (1997) Genes Dev , vol.11 , pp. 3206-3217
    • Alspaugh, J.A.1    Perfect, J.R.2    Heitman, J.3
  • 2
    • 3342963000 scopus 로고    scopus 로고
    • Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response
    • Apidianakis, Y., Rahme, L.G., Heitman, J., Ausubel, F.M., Calderwood, S.B., and Mylonakis, E. (2004) Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response. Eukaryot Cell 3: 413-419.
    • (2004) Eukaryot Cell , vol.3 , pp. 413-419
    • Apidianakis, Y.1    Rahme, L.G.2    Heitman, J.3    Ausubel, F.M.4    Calderwood, S.B.5    Mylonakis, E.6
  • 4
    • 0031213571 scopus 로고    scopus 로고
    • Mammalian homologues of C. elegans PAR-1 are asymmetrically localized in epithelial cells and may influence their polarity
    • Bohm, H., Brinkmann, V., Drab, M., Henske, A., and Kurzchalia, T.V. (1997) Mammalian homologues of C. elegans PAR-1 are asymmetrically localized in epithelial cells and may influence their polarity. Curr Biol 7: 603-606.
    • (1997) Curr Biol , vol.7 , pp. 603-606
    • Bohm, H.1    Brinkmann, V.2    Drab, M.3    Henske, A.4    Kurzchalia, T.V.5
  • 5
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner, S. (1974) The genetics of Caenorhabditis elegans. Genetics 77: 71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 6
    • 0032921678 scopus 로고    scopus 로고
    • Application of a rapid method (targeted display) for the identification of differentially expressed mRNAs following NGF-induced neuronal differentiation in PC12 cells
    • Brown, A.J., Hutchings, C., Burke, J.F., and Mayne, L.V. (1999) Application of a rapid method (targeted display) for the identification of differentially expressed mRNAs following NGF-induced neuronal differentiation in PC12 cells. Mol Cell Neurosci 13: 119-130.
    • (1999) Mol Cell Neurosci , vol.13 , pp. 119-130
    • Brown, A.J.1    Hutchings, C.2    Burke, J.F.3    Mayne, L.V.4
  • 9
    • 0043197395 scopus 로고    scopus 로고
    • 'Ready made' virulence and 'dual use' virulence factors in pathogenic environmental fungi - The Cryptococcus neoformans paradigm
    • Casadevall, A., Steenbergen, J.N., and Nosanchuk, J.D. (2003) 'Ready made' virulence and 'dual use' virulence factors in pathogenic environmental fungi - the Cryptococcus neoformans paradigm. Curr Opin Microbiol 6: 332-337.
    • (2003) Curr Opin Microbiol , vol.6 , pp. 332-337
    • Casadevall, A.1    Steenbergen, J.N.2    Nosanchuk, J.D.3
  • 10
    • 0035936575 scopus 로고    scopus 로고
    • Drosophila par-1 is required for oocyte differentiation and microtubule organization
    • Cox, D.N., Lu, B., Sun, T.Q., Williams, L.T., and Jan, Y.N. (2001) Drosophila par-1 is required for oocyte differentiation and microtubule organization. Curr Biol 11: 75-87.
    • (2001) Curr Biol , vol.11 , pp. 75-87
    • Cox, D.N.1    Lu, B.2    Sun, T.Q.3    Williams, L.T.4    Jan, Y.N.5
  • 12
    • 0142184503 scopus 로고    scopus 로고
    • The protein kinase kin1, the fission yeast orthologue of mammalian MARK/PAR-1, localises to new cell ends after mitosis and is important for bipolar growth
    • Drewes, G., and Nurse, P. (2003) The protein kinase kin1, the fission yeast orthologue of mammalian MARK/PAR-1, localises to new cell ends after mitosis and is important for bipolar growth. FEBS Lett 554: 45-49.
    • (2003) FEBS Lett , vol.554 , pp. 45-49
    • Drewes, G.1    Nurse, P.2
  • 14
    • 0035370561 scopus 로고    scopus 로고
    • Intracellular parasitism of macrophages by Cryptococcus neoformans
    • Feldmesser, M., Tucker, S., and Casadevall, A. (2001) Intracellular parasitism of macrophages by Cryptococcus neoformans. Trends Microbiol 9: 273-278.
    • (2001) Trends Microbiol , vol.9 , pp. 273-278
    • Feldmesser, M.1    Tucker, S.2    Casadevall, A.3
  • 15
    • 0142216112 scopus 로고    scopus 로고
    • Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: Implications for an outbreak on Vancouver Island, Canada
    • Fraser, J.A., Subaran, R.L., Nichols, C.B., and Heitman, J. (2003) Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: implications for an outbreak on Vancouver Island, Canada. Eukaryot Cell 2: 1036-1045.
    • (2003) Eukaryot Cell , vol.2 , pp. 1036-1045
    • Fraser, J.A.1    Subaran, R.L.2    Nichols, C.B.3    Heitman, J.4
  • 16
    • 0036015636 scopus 로고    scopus 로고
    • Characterization of Burkholderia pseudomallei infection and identification of novel virulence factors using a Caenorhabditis elegans host system
    • Gan, Y.H., Chua, K.L., Chua, H.H., Liu, B., Hii, C.S., Chong, H.L., and Tan, P. (2002) Characterization of Burkholderia pseudomallei infection and identification of novel virulence factors using a Caenorhabditis elegans host system. Mol Microbiol 44: 1185-1197.
    • (2002) Mol Microbiol , vol.44 , pp. 1185-1197
    • Gan, Y.H.1    Chua, K.L.2    Chua, H.H.3    Liu, B.4    Hii, C.S.5    Chong, H.L.6    Tan, P.7
  • 18
    • 0025820447 scopus 로고
    • Ca(2+)-independent F-actin assembly and disassembly during Fc receptor-mediated phagocytosis in mouse macrophages
    • Greenberg, S., El Khoury, J., di Virgilio, F., Kaplan, E.M., and Silverstein, S.C. (1991) Ca(2+)-independent F-actin assembly and disassembly during Fc receptor-mediated phagocytosis in mouse macrophages. J Cell Biol 113: 757-767.
    • (1991) J Cell Biol , vol.113 , pp. 757-767
    • Greenberg, S.1    El Khoury, J.2    Di Virgilio, F.3    Kaplan, E.M.4    Silverstein, S.C.5
  • 19
    • 2042522697 scopus 로고    scopus 로고
    • Microorganisms resistant to free-living amoebae
    • Greub, G., and Raoult, D. (2004) Microorganisms resistant to free-living amoebae. Clin Microbiol Rev 17: 413-433.
    • (2004) Clin Microbiol Rev , vol.17 , pp. 413-433
    • Greub, G.1    Raoult, D.2
  • 20
    • 0029024475 scopus 로고
    • par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
    • Guo, S., and Kemphues, K.J. (1995) par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81: 611-620.
    • (1995) Cell , vol.81 , pp. 611-620
    • Guo, S.1    Kemphues, K.J.2
  • 21
    • 0030217996 scopus 로고    scopus 로고
    • Molecular genetics of asymmetric cleavage in the early Caenorhabditis elegans embryo
    • Guo, S., and Kemphues, K.J. (1996) Molecular genetics of asymmetric cleavage in the early Caenorhabditis elegans embryo. Curr Opin Genet Dev 6: 408-415.
    • (1996) Curr Opin Genet Dev , vol.6 , pp. 408-415
    • Guo, S.1    Kemphues, K.J.2
  • 23
    • 0034663992 scopus 로고    scopus 로고
    • Deficient in vitro and in vivo phagocytosis of apoptotic T cells by resident murine alveolar macrophages
    • Hu, B., Sonstein, J., Christensen, P.J., Punturieri, A., and Curtis, J.L. (2000) Deficient in vitro and in vivo phagocytosis of apoptotic T cells by resident murine alveolar macrophages. J Immunol 165: 2124-2133.
    • (2000) J Immunol , vol.165 , pp. 2124-2133
    • Hu, B.1    Sonstein, J.2    Christensen, P.J.3    Punturieri, A.4    Curtis, J.L.5
  • 24
    • 0032032243 scopus 로고    scopus 로고
    • IL-5 is required for eosinophil recruitment, crystal deposition, and mononuclear cell recruitment during a pulmonary Cryptococcus neoformans infection in genetically susceptible mice (C57BL/6)
    • Huffnagle, G.B., Boyd, M.B., Street, N.E., and Lipscomb, M.F. (1998) IL-5 is required for eosinophil recruitment, crystal deposition, and mononuclear cell recruitment during a pulmonary Cryptococcus neoformans infection in genetically susceptible mice (C57BL/6). J Immunol 160: 2393-2400.
    • (1998) J Immunol , vol.160 , pp. 2393-2400
    • Huffnagle, G.B.1    Boyd, M.B.2    Street, N.E.3    Lipscomb, M.F.4
  • 25
    • 4143077083 scopus 로고    scopus 로고
    • Cryptococcus neoformans virulence gene discovery through insertional mutagenesis
    • Idnurm, A., Reedy, J.L., Nussbaum, J.C., and Heitman, J. (2004) Cryptococcus neoformans virulence gene discovery through insertional mutagenesis. Eukaryot Cell 3: 420-429.
    • (2004) Eukaryot Cell , vol.3 , pp. 420-429
    • Idnurm, A.1    Reedy, J.L.2    Nussbaum, J.C.3    Heitman, J.4
  • 27
    • 0035037329 scopus 로고    scopus 로고
    • Microtubules and actin cytoskeleton in Cryptococcus neoformans compared with ascomycetous budding and fission yeasts
    • Kopecka, M., Gabriel, M., Takeo, K., Yamaguchi, M., Svoboda, A., Ohkusu, M., et al. (2001) Microtubules and actin cytoskeleton in Cryptococcus neoformans compared with ascomycetous budding and fission yeasts. Eur J Cell Biol 80: 303-311.
    • (2001) Eur J Cell Biol , vol.80 , pp. 303-311
    • Kopecka, M.1    Gabriel, M.2    Takeo, K.3    Yamaguchi, M.4    Svoboda, A.5    Ohkusu, M.6
  • 28
    • 0344091555 scopus 로고    scopus 로고
    • Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening
    • Kurz, C.L., Chauvet, S., Andres, E., Aurouze, M., Vallet, I., Michel, G.P., et al. (2003) Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening. EMBO J 22: 1451-1460.
    • (2003) EMBO J , vol.22 , pp. 1451-1460
    • Kurz, C.L.1    Chauvet, S.2    Andres, E.3    Aurouze, M.4    Vallet, I.5    Michel, G.P.6
  • 29
    • 0025087142 scopus 로고
    • A putative protein kinase gene (kin1+) is important for growth polarity in Schizosaccharomyces pombe
    • Levin, D.E., and Bishop, B.J. (1990) A putative protein kinase gene (kin1+) is important for growth polarity in Schizosaccharomyces pombe. Proc Natl Acad Sci USA 87: 8272-8276.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 8272-8276
    • Levin, D.E.1    Bishop, B.J.2
  • 31
    • 0041322875 scopus 로고    scopus 로고
    • Updated view of Cryptococcus neoformans mating type and virulence
    • Mitchell, A.P. (2003) Updated view of Cryptococcus neoformans mating type and virulence. Infect Immun 71: 4829-4830.
    • (2003) Infect Immun , vol.71 , pp. 4829-4830
    • Mitchell, A.P.1
  • 32
    • 0032743056 scopus 로고    scopus 로고
    • Inositol synthesis and catabolism in Cryptococcus neoformans
    • Molina, Y., Ramos, S.E., Douglass, T., and Klig, L.S. (1999) Inositol synthesis and catabolism in Cryptococcus neoformans. Yeast 15: 1657-1667.
    • (1999) Yeast , vol.15 , pp. 1657-1667
    • Molina, Y.1    Ramos, S.E.2    Douglass, T.3    Klig, L.S.4
  • 33
    • 0033549902 scopus 로고    scopus 로고
    • Soluble guanylyl cyclases in Caenorhabditis elegans: NO is not the answer
    • Morton, D.B., Hudson, M.L., Waters, E., and O'Shea, M. (1999) Soluble guanylyl cyclases in Caenorhabditis elegans: NO is not the answer. Curr Biol 9: R546-R547.
    • (1999) Curr Biol , vol.9
    • Morton, D.B.1    Hudson, M.L.2    Waters, E.3    O'Shea, M.4
  • 34
    • 0242291866 scopus 로고    scopus 로고
    • Asymptomatic pulmonary cryptococcosis in solid organ transplantation: Report of four cases and review of the literature
    • Mueller, N.J., and Fishman, J.A. (2003) Asymptomatic pulmonary cryptococcosis in solid organ transplantation: report of four cases and review of the literature. Transpl Infect Dis 5: 140-143.
    • (2003) Transpl Infect Dis , vol.5 , pp. 140-143
    • Mueller, N.J.1    Fishman, J.A.2
  • 35
    • 0037180512 scopus 로고    scopus 로고
    • Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis
    • Mylonakis, E., Ausubel, F.M., Perfect, J.R., Heitman, J., and Calderwood, S.B. (2002) Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis. Proc Natl Acad Sci USA 99: 15675-15680.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15675-15680
    • Mylonakis, E.1    Ausubel, F.M.2    Perfect, J.R.3    Heitman, J.4    Calderwood, S.B.5
  • 36
    • 0041971075 scopus 로고    scopus 로고
    • Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates
    • Nielsen, K., Cox, G.M., Wang, P., Toffaletti, D.L., Perfect, J.R., and Heitman, J. (2003) Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates. Infect Immun 71: 4831-4841.
    • (2003) Infect Immun , vol.71 , pp. 4831-4841
    • Nielsen, K.1    Cox, G.M.2    Wang, P.3    Toffaletti, D.L.4    Perfect, J.R.5    Heitman, J.6
  • 38
    • 0035909926 scopus 로고    scopus 로고
    • Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages
    • Steenbergen, J.N., Shuman, H.A., and Casadevall, A. (2001) Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages. Proc Natl Acad Sci USA 98: 15245-15250.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 15245-15250
    • Steenbergen, J.N.1    Shuman, H.A.2    Casadevall, A.3
  • 39
    • 0041823555 scopus 로고    scopus 로고
    • Cryptococcus neoformans virulence is enhanced after growth in the genetically malleable host Dictyostelium discoideum
    • Steenbergen, J.N., Nosanchuk, J.D., Malliaris, S.D., and Casadevall, A. (2003) Cryptococcus neoformans virulence is enhanced after growth in the genetically malleable host Dictyostelium discoideum. Infect Immun 71: 4862-4872.
    • (2003) Infect Immun , vol.71 , pp. 4862-4872
    • Steenbergen, J.N.1    Nosanchuk, J.D.2    Malliaris, S.D.3    Casadevall, A.4
  • 40
    • 0034598314 scopus 로고    scopus 로고
    • Protection from lethal gram-positive infection by macrophage scavenger receptor-dependent phagocytosis
    • Thomas, C.A., Li, Y., Kodama, T., Suzuki, H., Silverstein, S.C., and El Khoury, J. (2000) Protection from lethal gram-positive infection by macrophage scavenger receptor-dependent phagocytosis. J Exp Med 191: 147-156.
    • (2000) J Exp Med , vol.191 , pp. 147-156
    • Thomas, C.A.1    Li, Y.2    Kodama, T.3    Suzuki, H.4    Silverstein, S.C.5    El Khoury, J.6
  • 41
    • 0028362112 scopus 로고
    • KIN1 and KIN2 protein kinases localize to the cytoplasmic face of the yeast plasma membrane
    • Tibbetts, M., Donovan, M., Roe, S., Stiltner, A.M., and Hammond, C.I. (1994) KIN1 and KIN2 protein kinases localize to the cytoplasmic face of the yeast plasma membrane. Exp Cell Res 213: 93-99.
    • (1994) Exp Cell Res , vol.213 , pp. 93-99
    • Tibbetts, M.1    Donovan, M.2    Roe, S.3    Stiltner, A.M.4    Hammond, C.I.5
  • 42
    • 0033775722 scopus 로고    scopus 로고
    • A Drosophila melanogaster homologue of Caenorhabditis elegans par-1 acts at an early step in embryonic-axis formation
    • Tomancak, P., Piano, F., Riechmann, V., Gunsalus, K.C., Kemphues, K.J., and Ephrussi, A. (2000) A Drosophila melanogaster homologue of Caenorhabditis elegans par-1 acts at an early step in embryonic-axis formation. Nat Cell Biol 2: 458-460.
    • (2000) Nat Cell Biol , vol.2 , pp. 458-460
    • Tomancak, P.1    Piano, F.2    Riechmann, V.3    Gunsalus, K.C.4    Kemphues, K.J.5    Ephrussi, A.6
  • 43
    • 0033620625 scopus 로고    scopus 로고
    • Characterization of the glyceraldehyde-3-phosphate dehydrogenase gene [correction of glyceraldehyde-3-phosphate gene] and the use of its promoter for heterologous expression in Cryptococcus neoformans, a human pathogen
    • Varma, A., and Kwon-Chung, K.J. (1999) Characterization of the glyceraldehyde-3-phosphate dehydrogenase gene [correction of glyceraldehyde-3-phosphate gene] and the use of its promoter for heterologous expression in Cryptococcus neoformans, a human pathogen. Gene 232: 155-163.
    • (1999) Gene , vol.232 , pp. 155-163
    • Varma, A.1    Kwon-Chung, K.J.2
  • 44
    • 0036148490 scopus 로고    scopus 로고
    • Ras1 and Ras2 contribute shared and unique roles in physiology and virulence of Cryptococcus neoformans
    • Waugh, M.S., Nichols, C.B., DeCesare, C.M., Cox, G.M., Heitman, J., and Alspaugh, J.A. (2002) Ras1 and Ras2 contribute shared and unique roles in physiology and virulence of Cryptococcus neoformans. Microbiology 148: 191-201.
    • (2002) Microbiology , vol.148 , pp. 191-201
    • Waugh, M.S.1    Nichols, C.B.2    DeCesare, C.M.3    Cox, G.M.4    Heitman, J.5    Alspaugh, J.A.6
  • 45
    • 0024369960 scopus 로고
    • Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies
    • Woods, A., Sherwin, T., Sasse, R., MacRae, T.H., Baines, A.J., and Gull, K. (1989) Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies. J Cell Sci 93: 491-500.
    • (1989) J Cell Sci , vol.93 , pp. 491-500
    • Woods, A.1    Sherwin, T.2    Sasse, R.3    MacRae, T.H.4    Baines, A.J.5    Gull, K.6
  • 46
    • 0036896593 scopus 로고    scopus 로고
    • Effect of auristatin PHE on microtubule integrity and nuclear localization in Cryptococcus neoformans
    • Woyke, T., Roberson, R.W., Pettit, G.R., Winkelmann, G., and Pettit, R.K. (2002) Effect of auristatin PHE on microtubule integrity and nuclear localization in Cryptococcus neoformans. Antimicrob Agents Chemother 46: 3802-3808.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 3802-3808
    • Woyke, T.1    Roberson, R.W.2    Pettit, G.R.3    Winkelmann, G.4    Pettit, R.K.5


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