-
1
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Errata, Nature 2001;411:720, 412:565
-
Lander ES, Linton LM, Birren B, et al. Initial sequencing and analysis of the human genome. Nature 2001;409:860-921. [Errata, Nature 2001;411:720, 412:565.]
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
-
2
-
-
0035895505
-
The sequence of the human genome
-
Erratum, Science 2001;292:1838
-
Venter JC, Adams MD, Myers EW, et al. The sequence of the human genome. Science 2001;291:1304-51. [Erratum, Science 2001;292:1838.]
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
-
3
-
-
0035998736
-
Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders
-
Hamosh A, Scott AF, Amberger J, Bocchini C, Valle D, McKusick VA. Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. (Also available at http:// www.ncbi.nlm. nih.govlomim.) Nucleic Acids Res 2002;30:52-5.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 52-55
-
-
Hamosh, A.1
Scott, A.F.2
Amberger, J.3
Bocchini, C.4
Valle, D.5
McKusick, V.A.6
-
4
-
-
0020358654
-
A genetic switch in a bacterial virus
-
Ptashne M, Johnson AD, Pabo CO. A genetic switch in a bacterial virus. Sci Am 1982;247:128-30, 132, 134-40.
-
(1982)
Sci Am
, vol.247
, pp. 128-130
-
-
Ptashne, M.1
Johnson, A.D.2
Pabo, C.O.3
-
6
-
-
0032509302
-
Genome sequence of the nematode C. elegans: A platform for investigating biology
-
Errata, Science 1999;283:35, 2103, 285:0 1493. 3
-
The C. elegans Sequencing Consortium. Genome sequence of the nematode C. elegans: a platform for investigating biology. Science 1998;282:2012-8. [Errata, Science 1999;283:35, 2103, 285: 1493.3
-
(1998)
Science
, vol.282
, pp. 2012-2018
-
-
-
7
-
-
0034708480
-
The genome sequence of Drosophila melanogaster
-
Adams MD, Celniker SE, Holt RA, et al. The genome sequence of Drosophila melanogaster. Science 2000;287:2185-95.
-
(2000)
Science
, vol.287
, pp. 2185-2195
-
-
Adams, M.D.1
Celniker, S.E.2
Holt, R.A.3
-
8
-
-
0035458366
-
The art and design of genetic screens: Yeast
-
Forsburg SL. The art and design of genetic screens: yeast. Nat Rev Genet 2001;2:659-68.
-
(2001)
Nat Rev Genet
, vol.2
, pp. 659-668
-
-
Forsburg, S.L.1
-
9
-
-
0036244951
-
The art and design of genetic screens: Drosophila melanogaster
-
St Johnston D. The art and design of genetic screens: Drosophila melanogaster. Nat Rev Genet 2002;3:176-88.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 176-188
-
-
St Johnston, D.1
-
10
-
-
0036254584
-
The art and design of genetic screens: Caenorhabditis elegans
-
Jorgensen EM, Mango SE. The art and design of genetic screens: Caenorhabditis elegans. Nat Rev Genet 2002;3:356-69.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 356-369
-
-
Jorgensen, E.M.1
Mango, S.E.2
-
11
-
-
0035657098
-
The art and design of genetic screens: Zebrafish
-
Patton EE, Zon LI. The art and design of genetic screens: zebrafish. Nat Rev Genet 2001;2:956-66.
-
(2001)
Nat Rev Genet
, vol.2
, pp. 956-966
-
-
Patton, E.E.1
Zon, L.I.2
-
12
-
-
0034708444
-
Comparative genomics of the eukaryotes
-
Rubin GM, Yandell MD, Wortman JR, et al. Comparative genomics of the eukaryotes. Science 2000;287:2204-15.
-
(2000)
Science
, vol.287
, pp. 2204-2215
-
-
Rubin, G.M.1
Yandell, M.D.2
Wortman, J.R.3
-
13
-
-
0034837386
-
A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster
-
Reiter LT, Potocki L, Chien S, Gribskov M, Bier E. A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster. Genome Res 2001;11:1114-25.
-
(2001)
Genome Res
, vol.11
, pp. 1114-1125
-
-
Reiter, L.T.1
Potocki, L.2
Chien, S.3
Gribskov, M.4
Bier, E.5
-
15
-
-
0347785481
-
Myc-induced T cell leukemia in transgenic zebrafish
-
Langenau DM, Traver D, Ferrando AA, et al. Myc-induced T cell leukemia in transgenic zebrafish. Science 2003;299:887-90.
-
(2003)
Science
, vol.299
, pp. 887-890
-
-
Langenau, D.M.1
Traver, D.2
Ferrando, A.A.3
-
16
-
-
0014804012
-
Genetic control of the cell-division cycle in yeast. I. Detection of mutants
-
Hartwell LH, Culotti J, Reid B. Genetic control of the cell-division cycle in yeast. I. Detection of mutants. Proc Natl Acad Sci U S A 1970;66:352-9.
-
(1970)
Proc Natl Acad Sci U S A
, vol.66
, pp. 352-359
-
-
Hartwell, L.H.1
Culotti, J.2
Reid, B.3
-
17
-
-
0017157413
-
Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe
-
Nurse P, Thuriaux P, Nasmyth K. Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe. Mol Gen Genet 1976;146:167-78.
-
(1976)
Mol Gen Genet
, vol.146
, pp. 167-178
-
-
Nurse, P.1
Thuriaux, P.2
Nasmyth, K.3
-
18
-
-
0024425887
-
Checkpoints: Controls that ensure the order of cell cycle events
-
Hartwell LH, Weinert TA. Checkpoints: controls that ensure the order of cell cycle events. Science 1989;246:629-34.
-
(1989)
Science
, vol.246
, pp. 629-634
-
-
Hartwell, L.H.1
Weinert, T.A.2
-
19
-
-
0019133661
-
Mutations affecting segment number and polarity in Drosophila
-
Nusslein-Volhard C, Wieschaus E. Mutations affecting segment number and polarity in Drosophila. Nature 1980;287:795-801.
-
(1980)
Nature
, vol.287
, pp. 795-801
-
-
Nusslein-Volhard, C.1
Wieschaus, E.2
-
20
-
-
0022497852
-
Genetic control of programmed cell death in the nematode C. elegans
-
Ellis HM, Horvitz HR. Genetic control of programmed cell death in the nematode C. elegans. Cell 1986;44:817-29.
-
(1986)
Cell
, vol.44
, pp. 817-829
-
-
Ellis, H.M.1
Horvitz, H.R.2
-
21
-
-
0027742295
-
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
-
Fishel R, Lescoe MK, Rao MR, et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993;75:1027-38.
-
(1993)
Cell
, vol.75
, pp. 1027-1038
-
-
Fishel, R.1
Lescoe, M.K.2
Rao, M.R.3
-
22
-
-
15844386165
-
Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome
-
Hahn H, Wicking C, Zaphiropoulous PG, et al. Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 1996;85:841-51.
-
(1996)
Cell
, vol.85
, pp. 841-851
-
-
Hahn, H.1
Wicking, C.2
Zaphiropoulous, P.G.3
-
23
-
-
15844381336
-
Human homolog of patched, a candidate gene for the basal cell nevus syndrome
-
Johnson RL, Rothman AL, Xie J, et al. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 1996;272:1668-71.
-
(1996)
Science
, vol.272
, pp. 1668-1671
-
-
Johnson, R.L.1
Rothman, A.L.2
Xie, J.3
-
24
-
-
0035921849
-
Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line
-
Strohmaier H, Spruck CH, Kaiser P, Won KA, Sangfelt O, Reed SI. Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line. Nature 2001;413:316-22.
-
(2001)
Nature
, vol.413
, pp. 316-322
-
-
Strohmaier, H.1
Spruck, C.H.2
Kaiser, P.3
Won, K.A.4
Sangfelt, O.5
Reed, S.I.6
-
25
-
-
0035921928
-
Archipelago regulates cyclin E levels in Drosophila and is mutated in human cancer cell lines
-
Moberg KH, Bell DW, Wahrer DC, Haber DA, Hariharan IK. Archipelago regulates cyclin E levels in Drosophila and is mutated in human cancer cell lines. Nature 2001;413:311-6.
-
(2001)
Nature
, vol.413
, pp. 311-316
-
-
Moberg, K.H.1
Bell, D.W.2
Wahrer, D.C.3
Haber, D.A.4
Hariharan, I.K.5
-
26
-
-
0035812709
-
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
-
Koepp DM, Schaefer LK, Ye X, et al. Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase. Science 2001;294:173-7.
-
(2001)
Science
, vol.294
, pp. 173-177
-
-
Koepp, D.M.1
Schaefer, L.K.2
Ye, X.3
-
27
-
-
0037102310
-
hCDC4 Gene mutations in endometrial cancer
-
Spruck CH, Strohmaier H, Sangfelt O, et al. hCDC4 Gene mutations in endometrial cancer. Cancer Res 2002;62:4535-9.
-
(2002)
Cancer Res
, vol.62
, pp. 4535-4539
-
-
Spruck, C.H.1
Strohmaier, H.2
Sangfelt, O.3
-
28
-
-
0034677467
-
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
-
Donovan A, Brownlie A, Zhou Y, et al. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature 2000;403:776-81.
-
(2000)
Nature
, vol.403
, pp. 776-781
-
-
Donovan, A.1
Brownlie, A.2
Zhou, Y.3
-
29
-
-
17944380796
-
Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene
-
Montosi G, Donovan A, Totaro A, et al. Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene. J Clin Invest 2001;108:619-23.
-
(2001)
J Clin Invest
, vol.108
, pp. 619-623
-
-
Montosi, G.1
Donovan, A.2
Totaro, A.3
-
30
-
-
0034930197
-
A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis
-
Njajou OT, Vaessen N, Joosse M, et al. A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis. Nat Genet 2001;28:213-4.
-
(2001)
Nat Genet
, vol.28
, pp. 213-214
-
-
Njajou, O.T.1
Vaessen, N.2
Joosse, M.3
-
31
-
-
0034176088
-
Modeling human neurodegenerative diseases in Drosophila: On a wing and a prayer
-
Fortini ME, Bonini NM. Modeling human neurodegenerative diseases in Drosophila: on a wing and a prayer. Trends Genet 2000; 16:161-7.
-
(2000)
Trends Genet
, vol.16
, pp. 161-167
-
-
Fortini, M.E.1
Bonini, N.M.2
-
32
-
-
0034329159
-
Molecular genetics: Unmasking polyglutamine triggers in neurodegenerative disease
-
Gusella JF, MacDonald ME. Molecular genetics: unmasking polyglutamine triggers in neurodegenerative disease. Nat Rev Neurosci 2000;1:109-15.
-
(2000)
Nat Rev Neurosci
, vol.1
, pp. 109-115
-
-
Gusella, J.F.1
MacDonald, M.E.2
-
33
-
-
18544392423
-
Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila
-
Warrick JM, Paulson HL, Gray-Board GL, et al. Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila. Cell 1998;93-939-49.
-
(1998)
Cell
, vol.93
, pp. 939-949
-
-
Warrick, J.M.1
Paulson, H.L.2
Gray-Board, G.L.3
-
34
-
-
0032168160
-
Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons
-
Jackson GR, Salecker I, Dong X, et al. Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons. Neuron 1998;21:633-42.
-
(1998)
Neuron
, vol.21
, pp. 633-642
-
-
Jackson, G.R.1
Salecker, I.2
Dong, X.3
-
35
-
-
0033524413
-
Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron
-
Faber PW, Alter JR, MacDonald ME, Hart AC. Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron. Proc Natl Acad Sci U S A 1999;96:179-84.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 179-184
-
-
Faber, P.W.1
Alter, J.R.2
MacDonald, M.E.3
Hart, A.C.4
-
36
-
-
0032727617
-
Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70
-
Warrick JM, Chan HY, Gray-Board GL, Chai Y, Paulson HL, Bonini NM. Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70. Nat Genet 1999;23:425-8.
-
(1999)
Nat Genet
, vol.23
, pp. 425-428
-
-
Warrick, J.M.1
Chan, H.Y.2
Gray-Board, G.L.3
Chai, Y.4
Paulson, H.L.5
Bonini, N.M.6
-
37
-
-
0034629073
-
Genetic suppression of polyglutamine toxicity in Drosophila
-
Kazemi-Esfarjani P, Benzer S. Genetic suppression of polyglutamine toxicity in Drosophila. Science 2000;287:1837-40.
-
(2000)
Science
, vol.287
, pp. 1837-1840
-
-
Kazemi-Esfarjani, P.1
Benzer, S.2
-
38
-
-
0034597833
-
Identification of genes that modify ataxin-1-induced neurodegeneration
-
Fernandez-Funez P, Nino-Rosales ML, de Gouyon B, et al. Identification of genes that modify ataxin-1-induced neurodegeneration. Nature 2000;408:101-6.
-
(2000)
Nature
, vol.408
, pp. 101-106
-
-
Fernandez-Funez, P.1
Nino-Rosales, M.L.2
De Gouyon, B.3
-
39
-
-
0035909330
-
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
-
Steffan JS, Bodai L, Pallos J, et al. Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila. Nature 2001;413:739-43.
-
(2001)
Nature
, vol.413
, pp. 739-743
-
-
Steffan, J.S.1
Bodai, L.2
Pallos, J.3
-
40
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
Feany MB, Bender WW. A Drosophila model of Parkinson's disease. Nature 2000;404:394-8.
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
41
-
-
18444417998
-
aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation
-
Francis R, McGrath G, Zhang J, et al. aph-1 And pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation. Dev Cell 2002;3:85-97.
-
(2002)
Dev Cell
, vol.3
, pp. 85-97
-
-
Francis, R.1
McGrath, G.2
Zhang, J.3
-
42
-
-
0037062951
-
RNA interference
-
Hannon GJ. RNA interference. Nature 2002;418:244-51.
-
(2002)
Nature
, vol.418
, pp. 244-251
-
-
Hannon, G.J.1
-
43
-
-
0037448540
-
Systematic functional analysis of the Caenorhabditis genome using RNAi
-
Kamath RS, Fraser AG, Dong Y, et al. Systematic functional analysis of the Caenorhabditis genome using RNAi. Nature 2003; 421:231-7.
-
(2003)
Nature
, vol.421
, pp. 231-237
-
-
Kamath, R.S.1
Fraser, A.G.2
Dong, Y.3
-
44
-
-
0037448528
-
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
-
Ashrafi K, Chang FY, Watts JL, et al. Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 2003; 421:268-72.
-
(2003)
Nature
, vol.421
, pp. 268-272
-
-
Ashrafi, K.1
Chang, F.Y.2
Watts, J.L.3
-
45
-
-
0034739045
-
Sheep, lilies and human genetics
-
Bale AB. Sheep, lilies and human genetics. Nature 2000;406: 944-5.
-
(2000)
Nature
, vol.406
, pp. 944-945
-
-
Bale, A.B.1
-
46
-
-
0037430991
-
Preimplantation diagnosis for sonic hedgehog mutation causing familial holoprosencephaly
-
Verlinsky Y, Rechitsky S, Verlinsky O, et al. Preimplantation diagnosis for sonic hedgehog mutation causing familial holoprosencephaly. N Engl J Med 2003;348:1449-54.
-
(2003)
N Engl J Med
, vol.348
, pp. 1449-1454
-
-
Verlinsky, Y.1
Rechitsky, S.2
Verlinsky, O.3
-
47
-
-
0034738979
-
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
-
Taipale J, Chen JK, Cooper MK, et al. Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine. Nature 2000;406:1005-9.
-
(2000)
Nature
, vol.406
, pp. 1005-1009
-
-
Taipale, J.1
Chen, J.K.2
Cooper, M.K.3
-
48
-
-
0036829397
-
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
-
Chen JK, Taipale J, Cooper MK, Beachy PA. Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. Genes Dev 2002;16:2743-8.
-
(2002)
Genes Dev
, vol.16
, pp. 2743-2748
-
-
Chen, J.K.1
Taipale, J.2
Cooper, M.K.3
Beachy, P.A.4
-
49
-
-
0034644525
-
TOR a central controller of cell growth
-
Schmelzle T, Hall MN. TOR, a central controller of cell growth. Cell 2000;103:253-62.
-
(2000)
Cell
, vol.103
, pp. 253-262
-
-
Schmelzle, T.1
Hall, M.N.2
-
50
-
-
0035805180
-
The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation
-
Tapon N, Ito N, Dickson BJ, Treisman JE, Hariharan IK. The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation. Cell 2001;105:345-55.
-
(2001)
Cell
, vol.105
, pp. 345-355
-
-
Tapon, N.1
Ito, N.2
Dickson, B.J.3
Treisman, J.E.4
Hariharan, I.K.5
-
51
-
-
0035805162
-
Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size
-
Potter CJ, Huang H, Xu T. Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size. Cell 2001;105:357-68.
-
(2001)
Cell
, vol.105
, pp. 357-368
-
-
Potter, C.J.1
Huang, H.2
Xu, T.3
-
52
-
-
0034982971
-
TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth
-
Gao X, Pan D. TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth. Genes Dev 2001;15:1383-92.
-
(2001)
Genes Dev
, vol.15
, pp. 1383-1392
-
-
Gao, X.1
Pan, D.2
-
53
-
-
0036501277
-
A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells
-
Kwiatkowski DJ, Zhang H, Bandura JL, et al. A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells. Hum Mol Genet 2002;11:525-34.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 525-534
-
-
Kwiatkowski, D.J.1
Zhang, H.2
Bandura, J.L.3
-
54
-
-
0037896069
-
The fly
-
Erdman DV, ed. Charlottesville: University of Virginia Institute for Advanced Technology in the Humanities
-
Blake W. The fly. In: Erdman DV, ed. The complete poetry and prose of William Blake. Rev. ed. Charlottesville: University of Virginia Institute for Advanced Technology in the Humanities, 1988.
-
(1988)
The Complete Poetry and Prose of William Blake. Rev. Ed.
-
-
Blake, W.1
|