-
1
-
-
0033813721
-
The ascent of pulmonary drug delivery
-
I. Gonda The ascent of pulmonary drug delivery J. Pharm. Sci. 87 2000 940 945
-
(2000)
J. Pharm. Sci.
, vol.87
, pp. 940-945
-
-
Gonda, I.1
-
2
-
-
0035111927
-
Treating systemic diseases via the lung
-
S. Sanjar, and J. Matthews Treating systemic diseases via the lung J. Aerosol. Med. 14 2001 S51 S58
-
(2001)
J. Aerosol. Med.
, vol.14
-
-
Sanjar, S.1
Matthews, J.2
-
3
-
-
0029090267
-
The controlled delivery of drugs to the lung
-
X.M. Zeng, G.P. Martin, and C. Marriott The controlled delivery of drugs to the lung Int. J. Pharm. 124 1995 149 164
-
(1995)
Int. J. Pharm.
, vol.124
, pp. 149-164
-
-
Zeng, X.M.1
Martin, G.P.2
Marriott, C.3
-
6
-
-
0030588714
-
Caco-2 monolayers in experimental and theoretical prediction of drug transport
-
P. Artursson, K. Palm, and K. Luthman Caco-2 monolayers in experimental and theoretical prediction of drug transport Adv. Drug Deliv. Rev. 22 1996 67 84
-
(1996)
Adv. Drug Deliv. Rev.
, vol.22
, pp. 67-84
-
-
Artursson, P.1
Palm, K.2
Luthman, K.3
-
7
-
-
0031413702
-
Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond
-
P. Artursson, and R.T. Borchardt Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond Pharm. Res. 14 1997 1655 1658
-
(1997)
Pharm. Res.
, vol.14
, pp. 1655-1658
-
-
Artursson, P.1
Borchardt, R.T.2
-
8
-
-
0142106303
-
Transporter-enzyme interactions: implications for predicting drug-drug interactions from in vitro data
-
L.Z. Benet, C.L. Cummins, and C.Y. Wu Transporter-enzyme interactions: implications for predicting drug-drug interactions from in vitro data Curr. Drug Metab. 4 2003 393 398
-
(2003)
Curr. Drug Metab.
, vol.4
, pp. 393-398
-
-
Benet, L.Z.1
Cummins, C.L.2
Wu, C.Y.3
-
9
-
-
0000556544
-
In vitro tests for respiratory toxicity - The report and recommendations of ECVAM workshop 18
-
C.R. Lambre, M. Aufderheide, R.E. Bolton, B. Fubini, H.P. Haagsman, P.M. Hext, M. Jorissen, Y. Landry, J.P. Morin, B. Nemery, P. Nettesheim, J. Pauluhn, R.J. Richards, A.E.M. Vickers, R. Wu, In vitro tests for respiratory toxicity - the report and recommendations of ECVAM workshop 18, ATLA 24, 1996, pp. 671-681.
-
(1996)
ATLA
, vol.24
, pp. 671-681
-
-
Lambre, C.R.1
Aufderheide, M.2
Bolton, R.E.3
Fubini, B.4
Haagsman, H.P.5
Hext, P.M.6
Jorissen, M.7
Landry, Y.8
Morin, J.P.9
Nemery, B.10
Nettesheim, P.11
Pauluhn, J.12
Richards, R.J.13
Vickers, A.E.M.14
Wu, R.15
-
10
-
-
0035313918
-
Methods used to assess pulmonary deposition and absorption of drugs
-
C. Mobley, and G. Hochhaus Methods used to assess pulmonary deposition and absorption of drugs Drug Discov. Today 6 2001 367 375
-
(2001)
Drug Discov. Today
, vol.6
, pp. 367-375
-
-
Mobley, C.1
Hochhaus, G.2
-
11
-
-
0017873165
-
Drug absorption from the lung
-
L.S. Schanker Drug absorption from the lung Biochem. Pharmacol. 27 1978 381 385
-
(1978)
Biochem. Pharmacol.
, vol.27
, pp. 381-385
-
-
Schanker, L.S.1
-
12
-
-
0031026464
-
Airway permeability and alveolar permeability and surface liquid thickness: theory
-
J. Widdecombe Airway permeability and alveolar permeability and surface liquid thickness: theory J. Appl. Physiol. 82 1997 3 12
-
(1997)
J. Appl. Physiol.
, vol.82
, pp. 3-12
-
-
Widdecombe, J.1
-
13
-
-
0036046741
-
Replacement, reduction, refinement
-
P. Flecknell Replacement, reduction, refinement ALTEX 19 2002 73 78
-
(2002)
ALTEX
, vol.19
, pp. 73-78
-
-
Flecknell, P.1
-
14
-
-
0036422569
-
The application of in vitro methods to safety pharmacology
-
I.D. Wakefield, C. Pollard, W.S. Redfern, T.G. Hammond, and J.P. Valentin The application of in vitro methods to safety pharmacology Fundam. Clin. Pharmacol. 16 2002 209 218
-
(2002)
Fundam. Clin. Pharmacol.
, vol.16
, pp. 209-218
-
-
Wakefield, I.D.1
Pollard, C.2
Redfern, W.S.3
Hammond, T.G.4
Valentin, J.P.5
-
15
-
-
84961244405
-
The biopharmaceutics classification system: highlights of FDA's draft guidance
-
A.J. Hussain, L.J. Lesko, K.Y. Lo, V.P. Shah, D. Volpe, and R.L. Williams The biopharmaceutics classification system: highlights of FDA's draft guidance Dissolution Technol. 6 1999 5 9
-
(1999)
Dissolution Technol.
, vol.6
, pp. 5-9
-
-
Hussain, A.J.1
Lesko, L.J.2
Lo, K.Y.3
Shah, V.P.4
Volpe, D.5
Williams, R.L.6
-
16
-
-
0037607679
-
Pulmonary absorption rate and bioavailability of drugs in vivo in rats: structure-absorption relationships and physicochemical profiling of inhaled drugs
-
A. Tronde, B. Norden, H. Marchner, A.K. Wendel, H. Lennernas, and U.H. Bengtsson Pulmonary absorption rate and bioavailability of drugs in vivo in rats: structure-absorption relationships and physicochemical profiling of inhaled drugs J. Pharm. Sci. 92 2003 1216 1233
-
(2003)
J. Pharm. Sci.
, vol.92
, pp. 1216-1233
-
-
Tronde, A.1
Norden, B.2
Marchner, H.3
Wendel, A.K.4
Lennernas, H.5
Bengtsson, U.H.6
-
17
-
-
0033959120
-
Human airway epithelial cell lines for in vitro drug transport and metabolism studies
-
B. Forbes Human airway epithelial cell lines for in vitro drug transport and metabolism studies Pharm. Sci. Technol. Today 3 2000 18 27
-
(2000)
Pharm. Sci. Technol. Today
, vol.3
, pp. 18-27
-
-
Forbes, B.1
-
18
-
-
0030588581
-
Respiratory epithelial cell culture models for evaluation of ion and drug transport
-
N.R. Mathias, F. Yamashita, and V.H.L. Lee Respiratory epithelial cell culture models for evaluation of ion and drug transport Adv. Drug Deliv. Rev. 22 1996 215 249
-
(1996)
Adv. Drug Deliv. Rev.
, vol.22
, pp. 215-249
-
-
Mathias, N.R.1
Yamashita, F.2
Lee, V.H.L.3
-
20
-
-
0343171768
-
Expression of metallothionein protein in the lungs of Wistar rats and C57 and DBA mice exposed to cadmium oxide fumes
-
I.M. McKenna, T. Gordon, L.C. Chen, M.R. Anver, and M.P. Waalkes Expression of metallothionein protein in the lungs of Wistar rats and C57 and DBA mice exposed to cadmium oxide fumes Toxicol. Appl. Pharmacol. 153 1998 169 178
-
(1998)
Toxicol. Appl. Pharmacol.
, vol.153
, pp. 169-178
-
-
McKenna, I.M.1
Gordon, T.2
Chen, L.C.3
Anver, M.R.4
Waalkes, M.P.5
-
21
-
-
0033073433
-
Endothelin receptor distribution and function in the airways
-
P.J. Henry Endothelin receptor distribution and function in the airways Clin. Exp. Pharmacol. Physiol. 26 1999 16216 16217
-
(1999)
Clin. Exp. Pharmacol. Physiol.
, vol.26
, pp. 16216-16217
-
-
Henry, P.J.1
-
22
-
-
0035719828
-
The lung as a route for systemic delivery of therapeutic proteins and peptides
-
R.U. Agu, M.I. Ugwoke, M. Armand, R. Kinget, and N. Verbeke The lung as a route for systemic delivery of therapeutic proteins and peptides Respir. Res. 2 2001 198 209
-
(2001)
Respir. Res.
, vol.2
, pp. 198-209
-
-
Agu, R.U.1
Ugwoke, M.I.2
Armand, M.3
Kinget, R.4
Verbeke, N.5
-
23
-
-
0028087664
-
Drug delivery via the respiratory tract
-
P.R. Byron, and J.S. Patton Drug delivery via the respiratory tract J. Aerosol. Med. 7 1994 49 75
-
(1994)
J. Aerosol. Med.
, vol.7
, pp. 49-75
-
-
Byron, P.R.1
Patton, J.S.2
-
24
-
-
0037385148
-
Fundamentals of pulmonary drug delivery
-
D.A. Groneberg, C. Witt, U. Wagner, K.F. Chung, and A. Fischer Fundamentals of pulmonary drug delivery Respir. Med. 97 2003 382 387
-
(2003)
Respir. Med.
, vol.97
, pp. 382-387
-
-
Groneberg, D.A.1
Witt, C.2
Wagner, U.3
Chung, K.F.4
Fischer, A.5
-
25
-
-
0035963943
-
Caveolae as potential macromolecule trafficking compartments within alveolar epithelium
-
M. Gumbleton Caveolae as potential macromolecule trafficking compartments within alveolar epithelium Adv. Drug Deliv. Rev. 49 2001 281 300
-
(2001)
Adv. Drug Deliv. Rev.
, vol.49
, pp. 281-300
-
-
Gumbleton, M.1
-
26
-
-
0033925098
-
Sustained release drug delivery to the lungs - an option for the future
-
J.G. Hardy, and T.S. Chadwick Sustained release drug delivery to the lungs - an option for the future Clin. Pharmacokinet. 39 2000 1 4
-
(2000)
Clin. Pharmacokinet.
, vol.39
, pp. 1-4
-
-
Hardy, J.G.1
Chadwick, T.S.2
-
27
-
-
0344513087
-
Pulmonary drug delivery. Part I. Physiological factors affecting therapeutic effectiveness of aerosolized medications
-
N.R. Labiris, and M.B. Dolovich Pulmonary drug delivery. Part I. Physiological factors affecting therapeutic effectiveness of aerosolized medications Br. J. Clin. Pharmacol. 56 2003 588 599
-
(2003)
Br. J. Clin. Pharmacol.
, vol.56
, pp. 588-599
-
-
Labiris, N.R.1
Dolovich, M.B.2
-
28
-
-
0027670013
-
Mucociliary clearance and drug-delivery via the respiratory tract
-
A.B. Lansley Mucociliary clearance and drug-delivery via the respiratory tract Adv. Drug Deliv. Rev. 11 1993 299 327
-
(1993)
Adv. Drug Deliv. Rev.
, vol.11
, pp. 299-327
-
-
Lansley, A.B.1
-
29
-
-
0343058935
-
Mechanisms of macromolecule absorption by the lungs
-
J.S. Patton Mechanisms of macromolecule absorption by the lungs Adv. Drug Deliv. Rev. 19 1996 3 36
-
(1996)
Adv. Drug Deliv. Rev.
, vol.19
, pp. 3-36
-
-
Patton, J.S.1
-
30
-
-
0031454495
-
Pulmonary drug delivery: physiologic and mechanistic aspects
-
J.W. Yu, and Y.W. Chien Pulmonary drug delivery: physiologic and mechanistic aspects Crit. Rev. Ther. Drug Carrier Syst. 14 1997 395 453
-
(1997)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.14
, pp. 395-453
-
-
Yu, J.W.1
Chien, Y.W.2
-
31
-
-
0344299169
-
Monolayers of human alveolar epithelial cells in primary culture for pulmonary absorption and transport studies
-
K.J. Elbert, U.F. Schäfer, H.J. Schäfers, K.J. Kim, V.H.L. Lee, and C.M. Lehr Monolayers of human alveolar epithelial cells in primary culture for pulmonary absorption and transport studies Pharm. Res. 16 1999 601 608
-
(1999)
Pharm. Res.
, vol.16
, pp. 601-608
-
-
Elbert, K.J.1
Schäfer, U.F.2
Schäfers, H.J.3
Kim, K.J.4
Lee, V.H.L.5
Lehr, C.M.6
-
32
-
-
0026636673
-
Differentiated structure and function of cultures from human tracheal epithelium
-
M. Yamaya, W.E. Finkbeiner, S.Y. Chun, and J.H. Widdecombe Differentiated structure and function of cultures from human tracheal epithelium Am. J. Physiol. 262 1992 L713 L724
-
(1992)
Am. J. Physiol.
, vol.262
-
-
Yamaya, M.1
Finkbeiner, W.E.2
Chun, S.Y.3
Widdecombe, J.H.4
-
33
-
-
0043125890
-
Effects of growth surface on differentiation of cultures of human tracheal epithelium
-
J.H. Widdecombe, L.A. Sachs, and W.E. Finkbeiner Effects of growth surface on differentiation of cultures of human tracheal epithelium In Vitro Cell Dev. Biol. 39 2003 51 55
-
(2003)
In Vitro Cell Dev. Biol.
, vol.39
, pp. 51-55
-
-
Widdecombe, J.H.1
Sachs, L.A.2
Finkbeiner, W.E.3
-
35
-
-
20444377151
-
-
http://www.mattek.com/pages/products/epiairway.
-
-
-
-
36
-
-
0027928745
-
CFTR expression chloride secretion in polarized immortal human bronchial epithelial cells
-
A.L. Cozens, M.J. Yezzi, K. Kunzelmann, T. Ohrui, L. Chin, K. Eng, W.E. Finkbeiner, J.H. Widdicombe, and D.C. Gruenert CFTR expression chloride secretion in polarized immortal human bronchial epithelial cells Am. J. Respir. Cell Mol. Biol. 10 1994 38 47
-
(1994)
Am. J. Respir. Cell Mol. Biol.
, vol.10
, pp. 38-47
-
-
Cozens, A.L.1
Yezzi, M.J.2
Kunzelmann, K.3
Ohrui, T.4
Chin, L.5
Eng, K.6
Finkbeiner, W.E.7
Widdicombe, J.H.8
Gruenert, D.C.9
-
37
-
-
0028307695
-
Calu-3: a human airway epithelial cell line that shows cAMP-dependent Cl-secretion
-
B.Q. Shen, W.E. Finkbeiner, J.J. Wine, R.J. Mrsny, and J.H. Widdicombe Calu-3: a human airway epithelial cell line that shows cAMP-dependent Cl-secretion Am. J. Physiol. 266 1994 L493 L501
-
(1994)
Am. J. Physiol.
, vol.266
-
-
Shen, B.Q.1
Finkbeiner, W.E.2
Wine, J.J.3
Mrsny, R.J.4
Widdicombe, J.H.5
-
38
-
-
0035989143
-
Influence of apical fluid volume on the development of functional intercellular junctions in the human epithelial cell line 16HBE14o-: implications for the use of this cell line as an in vitro model for bronchial drug absorption studies
-
C. Ehrhardt, C. Kneuer, J. Fiegel, J. Hanes, U.F. Schaefer, K.J. Kim, and C.M. Lehr Influence of apical fluid volume on the development of functional intercellular junctions in the human epithelial cell line 16HBE14o-: implications for the use of this cell line as an in vitro model for bronchial drug absorption studies Cell Tissue Res. 308 2002 391 400
-
(2002)
Cell Tissue Res.
, vol.308
, pp. 391-400
-
-
Ehrhardt, C.1
Kneuer, C.2
Fiegel, J.3
Hanes, J.4
Schaefer, U.F.5
Kim, K.J.6
Lehr, C.M.7
-
39
-
-
0037433812
-
The human bronchial epithelial cell line 16HBE14o- as a model system of the airways for studying drug transport
-
B. Forbes, A. Shah, G.P. Martin, and A.B. Lansley The human bronchial epithelial cell line 16HBE14o- as a model system of the airways for studying drug transport Int. J. Pharm. 257 2003 61 167
-
(2003)
Int. J. Pharm.
, vol.257
, pp. 61-167
-
-
Forbes, B.1
Shah, A.2
Martin, G.P.3
Lansley, A.B.4
-
40
-
-
0036125277
-
Permeability characteristics of Calu-3 human bronchial epithelial cells: in vitro-in vivo correlation to predict lung absorption in rats
-
N.R. Mathias, J. Timoszyk, P.I. Stetsko, J.R. Megill, R.L. Smith, and D.A. Wall Permeability characteristics of Calu-3 human bronchial epithelial cells: in vitro-in vivo correlation to predict lung absorption in rats J. Drug Target. 10 2002 31 40
-
(2002)
J. Drug Target.
, vol.10
, pp. 31-40
-
-
Mathias, N.R.1
Timoszyk, J.2
Stetsko, P.I.3
Megill, J.R.4
Smith, R.L.5
Wall, D.A.6
-
41
-
-
0242616312
-
Bronchial epithelial cell cultures
-
C.M. Lehr Taylor and Francis London
-
C. Meaney, B.I. Florea, C. Ehrhardt, U.F. Schaefer, C.M. Lehr, H.E. Junginger, and G. Borchard Bronchial epithelial cell cultures C.M. Lehr Cell Culture Models of Biological Barriers 2002 Taylor and Francis London 211 227
-
(2002)
Cell Culture Models of Biological Barriers
, pp. 211-227
-
-
Meaney, C.1
Florea, B.I.2
Ehrhardt, C.3
Schaefer, U.F.4
Lehr, C.M.5
Junginger, H.E.6
Borchard, G.7
-
42
-
-
0037458930
-
Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3
-
B.I. Florea, M.L. Cassara, H.E. Junginger, and G. Borchard Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3 J. Control Rel. 87 2003 131 138
-
(2003)
J. Control Rel.
, vol.87
, pp. 131-138
-
-
Florea, B.I.1
Cassara, M.L.2
Junginger, H.E.3
Borchard, G.4
-
43
-
-
0036282607
-
Insulin aggregation and asymmetric transport across human bronchial epithelial cell monolayers (Calu-3)
-
I. Pezron, R. Mitra, D. Pal, and A.K. Mitra Insulin aggregation and asymmetric transport across human bronchial epithelial cell monolayers (Calu-3) J. Pharm. Sci. 91 2002 1135 1146
-
(2002)
J. Pharm. Sci.
, vol.91
, pp. 1135-1146
-
-
Pezron, I.1
Mitra, R.2
Pal, D.3
Mitra, A.K.4
-
44
-
-
0028385690
-
Ciliogenesis in human bronchial epithelial cells cultured at the air-liquid interface
-
P.M. de Jong, M.A.J.A. van Sterkenberg, S.C. Hesseling, J.A. Kempenaar, A.A. Mulder, A.M. Mommaas, J.H. Dijkman, and M. Ponec Ciliogenesis in human bronchial epithelial cells cultured at the air-liquid interface Am. J. Respir. Cell Mol. Biol. 10 1994 271 299
-
(1994)
Am. J. Respir. Cell Mol. Biol.
, vol.10
, pp. 271-299
-
-
De Jong, P.M.1
Van Sterkenberg, M.A.J.A.2
Hesseling, S.C.3
Kempenaar, J.A.4
Mulder, A.A.5
Mommaas, A.M.6
Dijkman, J.H.7
Ponec, M.8
-
45
-
-
0242584998
-
Large porous particle impingement on lung epithelial cell monolayers - toward improved particle characterization in the lung
-
J. Fiegel, C. Ehrhardt, U.F. Schaefer, C.M. Lehr, and J. Hanes Large porous particle impingement on lung epithelial cell monolayers - toward improved particle characterization in the lung Pharm. Res. 20 2003 788 796
-
(2003)
Pharm. Res.
, vol.20
, pp. 788-796
-
-
Fiegel, J.1
Ehrhardt, C.2
Schaefer, U.F.3
Lehr, C.M.4
Hanes, J.5
-
46
-
-
0043092355
-
Do cell culture conditions influence the carrier-mediated transport of peptides in Caco-2 cell monolayers?
-
I. Behrens, and T. Kissel Do cell culture conditions influence the carrier-mediated transport of peptides in Caco-2 cell monolayers? Eur. J. Pharm. Sci. 19 2003 433 442
-
(2003)
Eur. J. Pharm. Sci.
, vol.19
, pp. 433-442
-
-
Behrens, I.1
Kissel, T.2
-
47
-
-
0030909506
-
The influence of culture time and passage number on the morphological and physiological development of Caco-2 cells
-
M.J. Briske-Anderson, J.W. Finley, and S.M. Newman The influence of culture time and passage number on the morphological and physiological development of Caco-2 cells Proc. Soc. Exp. Biol. Med. 214 1997 248 257
-
(1997)
Proc. Soc. Exp. Biol. Med.
, vol.214
, pp. 248-257
-
-
Briske-Anderson, M.J.1
Finley, J.W.2
Newman, S.M.3
-
48
-
-
0019977498
-
Cell number and cell characteristics of the normal human lung
-
J.D. Crapo, B.E. Barry, P. Gehr, M. Bachofen, and E.R. Weibel Cell number and cell characteristics of the normal human lung Am. Rev. Respir. Dis. 126 1982 332 337
-
(1982)
Am. Rev. Respir. Dis.
, vol.126
, pp. 332-337
-
-
Crapo, J.D.1
Barry, B.E.2
Gehr, P.3
Bachofen, M.4
Weibel, E.R.5
-
49
-
-
0035721766
-
Alveolar epithelial type II cell: defender of the alveolus revisited
-
H. Fehrenbach Alveolar epithelial type II cell: defender of the alveolus revisited Respir. Res. 2 2001 33 46
-
(2001)
Respir. Res.
, vol.2
, pp. 33-46
-
-
Fehrenbach, H.1
-
50
-
-
0038041946
-
Alveolar type I cells: molecular phenotype and development
-
M.C. Williams Alveolar type I cells: molecular phenotype and development Annu. Rev. Physiol. 65 2003 669 695
-
(2003)
Annu. Rev. Physiol.
, vol.65
, pp. 669-695
-
-
Williams, M.C.1
-
51
-
-
0034948869
-
A useful in vitro model for transport studies of alveolar epithelial barrier
-
K.J. Kim, Z. Borok, and E.D. Crandall A useful in vitro model for transport studies of alveolar epithelial barrier Pharm. Res. 18 2001 253 255
-
(2001)
Pharm. Res.
, vol.18
, pp. 253-255
-
-
Kim, K.J.1
Borok, Z.2
Crandall, E.D.3
-
52
-
-
0029101698
-
Permeability of peptides and proteins in human cultured alveolar A549 cell monolayer
-
S. Kobayashi, S. Kondo, and K. Juni Permeability of peptides and proteins in human cultured alveolar A549 cell monolayer Pharm. Res. 12 1995 1115 1119
-
(1995)
Pharm. Res.
, vol.12
, pp. 1115-1119
-
-
Kobayashi, S.1
Kondo, S.2
Juni, K.3
-
53
-
-
0347989344
-
Transport of proteins and peptides across human cultured alveolar A549 cell monolayer
-
Z. Wang, and Q. Zhang Transport of proteins and peptides across human cultured alveolar A549 cell monolayer Int. J. Pharm. 269 2004 451 456
-
(2004)
Int. J. Pharm.
, vol.269
, pp. 451-456
-
-
Wang, Z.1
Zhang, Q.2
-
54
-
-
0019988614
-
Dome formation in primary cultured monolayers of alveolar epithelial cells
-
B.E. Goodman, and E.D. Crandall Dome formation in primary cultured monolayers of alveolar epithelial cells Am. J. Physiol. 243 1982 C96 C100
-
(1982)
Am. J. Physiol.
, vol.243
-
-
Goodman, B.E.1
Crandall, E.D.2
-
55
-
-
0024467703
-
Type I cell-like morphology in tight alveolar epithelial monolayers
-
J.M. Cheek, M.J. Evans, and E.D. Crandall Type I cell-like morphology in tight alveolar epithelial monolayers Exp. Cell Res. 184 1989 3753 3787
-
(1989)
Exp. Cell Res.
, vol.184
, pp. 3753-3787
-
-
Cheek, J.M.1
Evans, M.J.2
Crandall, E.D.3
-
56
-
-
0028332971
-
Defined medium for primary culture de novo of adult rat alveolar epithelial cells
-
Z. Borok, S.I. Danto, S.M. Zabski, and E.D. Crandall Defined medium for primary culture de novo of adult rat alveolar epithelial cells In Vitro Cell Dev. Biol. 30A 1994 99 104
-
(1994)
In Vitro Cell Dev. Biol.
, vol.30
, pp. 99-104
-
-
Borok, Z.1
Danto, S.I.2
Zabski, S.M.3
Crandall, E.D.4
-
58
-
-
0032836421
-
Organic cation transport in rabbit alveolar epithelial cell monolayers
-
J. Shen, K.J. Elbert, F. Yamashita, C.M. Lehr, K.J. Kim, and V.H.L. Lee Organic cation transport in rabbit alveolar epithelial cell monolayers Pharm. Res. 16 1999 1280 1287
-
(1999)
Pharm. Res.
, vol.16
, pp. 1280-1287
-
-
Shen, J.1
Elbert, K.J.2
Yamashita, F.3
Lehr, C.M.4
Kim, K.J.5
Lee, V.H.L.6
-
59
-
-
0035236614
-
Marker transport across biological barriers in vitro: comparison of cell culture models for the gastrointestinal barrier, the blood-brain barrier and the alveolar epithelium of the lung
-
C. Gindorf, A. Steimer, C.M. Lehr, U. Bock, S. Schmitz, and E. Haltner Marker transport across biological barriers in vitro: comparison of cell culture models for the gastrointestinal barrier, the blood-brain barrier and the alveolar epithelium of the lung ALTEX 18 2001 155 165
-
(2001)
ALTEX
, vol.18
, pp. 155-165
-
-
Gindorf, C.1
Steimer, A.2
Lehr, C.M.3
Bock, U.4
Schmitz, S.5
Haltner, E.6
-
60
-
-
0021743744
-
Growth characteristics, morphology, and phospholipid composition of human type II pulmonary alveolar cells grown in a collagen-free microenvironment
-
G.E. Milo, G.A. Ackerman, and R.L. Sanders Growth characteristics, morphology, and phospholipid composition of human type II pulmonary alveolar cells grown in a collagen-free microenvironment In Vitro 20 1984 899 911
-
(1984)
In Vitro
, vol.20
, pp. 899-911
-
-
Milo, G.E.1
Ackerman, G.A.2
Sanders, R.L.3
-
61
-
-
1842858258
-
Differentiation of human alveolar epithelial cells in primary culture - morphological characterisation and expression of caveolin-1 and surfactant protein-C
-
S. Fuchs, A.J. Hollins, M. Laue, U.F. Schaefer, K. Roemer, M. Gumbleton, and C.M. Lehr Differentiation of human alveolar epithelial cells in primary culture - morphological characterisation and expression of caveolin-1 and surfactant protein-C Cell Tissue Res. 311 2003 31 45
-
(2003)
Cell Tissue Res.
, vol.311
, pp. 31-45
-
-
Fuchs, S.1
Hollins, A.J.2
Laue, M.3
Schaefer, U.F.4
Roemer, K.5
Gumbleton, M.6
Lehr, C.M.7
-
62
-
-
4243532656
-
-
Thesis, Saarland University, Saarbrücken, Germany
-
K.J. Elbert, Alveolare Epithelzellkultursysteme als in vitro-Modell für die pulmonale Absorption von Arzneistoffen, Thesis, Saarland University, Saarbrücken, Germany, 1998.
-
(1998)
Alveolare Epithelzellkultursysteme Als in Vitro-Modell Für Die Pulmonale Absorption Von Arzneistoffen
-
-
Elbert, K.J.1
-
63
-
-
0028847496
-
Epithelial lung cell marker: current tools for cell typing
-
M. Kasper, and G. Singh Epithelial lung cell marker: current tools for cell typing Histol. Histopathol. 10 1995 155 169
-
(1995)
Histol. Histopathol.
, vol.10
, pp. 155-169
-
-
Kasper, M.1
Singh, G.2
-
64
-
-
0035095067
-
Expression and localization of epithelial aquaporins in the adult human lung
-
S.M. Kreda, M.C. Gynn, D.A. Fenstermacher, R.C. Boucher, and S.E. Gabriel Expression and localization of epithelial aquaporins in the adult human lung Am. J. Respir. Cell Mol. Biol. 24 2001 224 234
-
(2001)
Am. J. Respir. Cell Mol. Biol.
, vol.24
, pp. 224-234
-
-
Kreda, S.M.1
Gynn, M.C.2
Fenstermacher, D.A.3
Boucher, R.C.4
Gabriel, S.E.5
-
65
-
-
0032921302
-
Caveolin and its cellular and subcellular immunolocalisation in lung alveolar epithelium: implications for alveolar type I cell function
-
G.R. Newman, L. Campbell, C. von Ruhland, B. Jasani, and M. Gumbleton Caveolin and its cellular and subcellular immunolocalisation in lung alveolar epithelium: implications for alveolar type I cell function Cell Tissue Res. 295 1999 111 120
-
(1999)
Cell Tissue Res.
, vol.295
, pp. 111-120
-
-
Newman, G.R.1
Campbell, L.2
Von Ruhland, C.3
Jasani, B.4
Gumbleton, M.5
-
66
-
-
1542330107
-
Receptor for advanced glycation end-products is a marker of type I lung alveolar cells
-
M. Shirasawa, N. Fujiwara, S. Hirabayashi, H. Ohno, J. Iida, K. Makita, and Y. Hata Receptor for advanced glycation end-products is a marker of type I lung alveolar cells Genes Cells 9 2004 165 174
-
(2004)
Genes Cells
, vol.9
, pp. 165-174
-
-
Shirasawa, M.1
Fujiwara, N.2
Hirabayashi, S.3
Ohno, H.4
Iida, J.5
Makita, K.6
Hata, Y.7
-
67
-
-
0032198791
-
Receptor for advanced glycation endproducts (RAGE) exhibits highly differential cellular and subcellular localisation in rat and human lung
-
H. Fehrenbach, M. Kasper, T. Tschernig, M.S. Shearman, D. Schuh, and M. Muller Receptor for advanced glycation endproducts (RAGE) exhibits highly differential cellular and subcellular localisation in rat and human lung Cell. Mol. Biol. 44 1998 1147 1157
-
(1998)
Cell. Mol. Biol.
, vol.44
, pp. 1147-1157
-
-
Fehrenbach, H.1
Kasper, M.2
Tschernig, T.3
Shearman, M.S.4
Schuh, D.5
Muller, M.6
-
68
-
-
0036765170
-
Heterocellular cultures of pulmonary alveolar epithelial cells grown on laminin-5 supplemented matrix
-
B.E. Isakson, G.J. Seedorf, R.L. Lubman, and S. Boitano Heterocellular cultures of pulmonary alveolar epithelial cells grown on laminin-5 supplemented matrix In Vitro Cell Dev. Biol. Anim. 38 2002 443 449
-
(2002)
In Vitro Cell Dev. Biol. Anim.
, vol.38
, pp. 443-449
-
-
Isakson, B.E.1
Seedorf, G.J.2
Lubman, R.L.3
Boitano, S.4
-
69
-
-
0001952404
-
Differences in drug transport across bronchial and gastrointestinal drug absorption models
-
B. Forbes, and A.B. Lansley Differences in drug transport across bronchial and gastrointestinal drug absorption models J. Pharm. Pharmacol. 50 1998 96
-
(1998)
J. Pharm. Pharmacol.
, vol.50
, pp. 96
-
-
Forbes, B.1
Lansley, A.B.2
-
70
-
-
0002673070
-
Transport characteristics of formoterol and salbutamol across a bronchial epithelial drug absorption model
-
B. Forbes, and A.B. Lansley Transport characteristics of formoterol and salbutamol across a bronchial epithelial drug absorption model Eur. J. Pharm. Sci. 6 1998 S24
-
(1998)
Eur. J. Pharm. Sci.
, vol.6
, pp. 24
-
-
Forbes, B.1
Lansley, A.B.2
-
71
-
-
4243952188
-
Calu-3 in the horizontal diffusion chamber system, a model of pulmonary drug transport
-
C.S. O'Shaughnessy, and E.S. Prosser Calu-3 in the horizontal diffusion chamber system, a model of pulmonary drug transport Pharm. Res. 13 1996 S169
-
(1996)
Pharm. Res.
, vol.13
, pp. 169
-
-
O'Shaughnessy, C.S.1
Prosser, E.S.2
-
72
-
-
0025311288
-
Epithelial transport of drugs in cell culture I. A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells
-
P. Artursson Epithelial transport of drugs in cell culture I. A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells J. Pharm. Sci. 79 1990 476 482
-
(1990)
J. Pharm. Sci.
, vol.79
, pp. 476-482
-
-
Artursson, P.1
-
73
-
-
0028126785
-
Influence of lipophilicity on beta-blocker permeation across rat alveolar epithelial monolayers
-
P. Saha, K.J. Kim, H. Yamahara, E.D. Crandall, and V.H.L. Lee Influence of lipophilicity on beta-blocker permeation across rat alveolar epithelial monolayers J. Control Rel. 32 1994 191 200
-
(1994)
J. Control Rel.
, vol.32
, pp. 191-200
-
-
Saha, P.1
Kim, K.J.2
Yamahara, H.3
Crandall, E.D.4
Lee, V.H.L.5
-
74
-
-
0032949615
-
MDCK (Madin-Darby canine kidney) cells: a tool for membrane permeability screening
-
J.D. Irvine, L. Takahashi, K. Lockhart, J. Cheong, J.W. Tolan, H.E. Selick, and J.R. Grove MDCK (Madin-Darby canine kidney) cells: a tool for membrane permeability screening J. Pharm. Sci. 88 1999 28 33
-
(1999)
J. Pharm. Sci.
, vol.88
, pp. 28-33
-
-
Irvine, J.D.1
Takahashi, L.2
Lockhart, K.3
Cheong, J.4
Tolan, J.W.5
Selick, H.E.6
Grove, J.R.7
-
75
-
-
0038408540
-
Drug absorption from the isolated perfused rat lung - correlations with drug physicochemical properties and epithelial permeability
-
A. Tronde, B. Norden, A.B. Jeppsson, P. Brunmark, E. Nilsson, H. Lennernas, and U.H. Bengtsson Drug absorption from the isolated perfused rat lung - correlations with drug physicochemical properties and epithelial permeability J. Drug Target. 11 2003 61 74
-
(2003)
J. Drug Target.
, vol.11
, pp. 61-74
-
-
Tronde, A.1
Norden, B.2
Jeppsson, A.B.3
Brunmark, P.4
Nilsson, E.5
Lennernas, H.6
Bengtsson, U.H.7
-
76
-
-
0034892459
-
Multidrug resistance-associated protein-1 functional activity in Calu-3 cells
-
K.O. Hamilton, E. Topp, I. Makagiansar, T. Siahaan, M. Yazdanian, and K.L. Audus Multidrug resistance-associated protein-1 functional activity in Calu-3 cells J. Pharmacol. Exp. Ther. 298 2001 1199 1205
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.298
, pp. 1199-1205
-
-
Hamilton, K.O.1
Topp, E.2
Makagiansar, I.3
Siahaan, T.4
Yazdanian, M.5
Audus, K.L.6
-
77
-
-
0017253226
-
Active transport of phenol red by rat lung slices
-
T.H. Gardiner, and L.S. Schanker Active transport of phenol red by rat lung slices J. Pharmacol. Exp. Ther. 196 1976 455 462
-
(1976)
J. Pharmacol. Exp. Ther.
, vol.196
, pp. 455-462
-
-
Gardiner, T.H.1
Schanker, L.S.2
-
78
-
-
0035132126
-
Localization of the peptide transporter PEPT2 in the lung: implications for pulmonary oligopeptide uptake
-
D.A. Groneberg, M. Nickolaus, J. Springer, F. Doring, H. Daniel, and A. Fischer Localization of the peptide transporter PEPT2 in the lung: implications for pulmonary oligopeptide uptake Am. J. Pathol. 158 2001 707 714
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 707-714
-
-
Groneberg, D.A.1
Nickolaus, M.2
Springer, J.3
Doring, F.4
Daniel, H.5
Fischer, A.6
-
80
-
-
12444302842
-
16HBE14o- human bronchial epithelial cell layers express P-glycoprotein, lung resistance-related protein, and caveolin-1
-
C. Ehrhardt, C. Kneuer, M. Laue, U.F. Schaefer, K.J. Kim, and C.M. Lehr 16HBE14o- human bronchial epithelial cell layers express P-glycoprotein, lung resistance-related protein, and caveolin-1 Pharm. Res. 20 2003 545 551
-
(2003)
Pharm. Res.
, vol.20
, pp. 545-551
-
-
Ehrhardt, C.1
Kneuer, C.2
Laue, M.3
Schaefer, U.F.4
Kim, K.J.5
Lehr, C.M.6
-
81
-
-
0036844744
-
Transport of HIV-gprotease inhibitors across 1 alpha,25di-hydroxy vitamin D3-treated Calu-3 cell monolayers: modulation of P-glycoprotein activity
-
J. Patel, D. Pal, V. Vangal, M. Gandhi, and A.L. Mitra Transport of HIV-gprotease inhibitors across 1 alpha,25di-hydroxy vitamin D3-treated Calu-3 cell monolayers: modulation of P-glycoprotein activity Pharm. Res. 19 2002 1696 1703
-
(2002)
Pharm. Res.
, vol.19
, pp. 1696-1703
-
-
Patel, J.1
Pal, D.2
Vangal, V.3
Gandhi, M.4
Mitra, A.L.5
-
82
-
-
0030784505
-
Transepithelial transport of the fluoroquinolone ciprofloxacin by human airway epithelial Calu-3 cells
-
M.E. Cavet, M. West, and N.L. Simmons Transepithelial transport of the fluoroquinolone ciprofloxacin by human airway epithelial Calu-3 cells Antimicrob. Agents Chemother. 41 1997 2693 2698
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 2693-2698
-
-
Cavet, M.E.1
West, M.2
Simmons, N.L.3
-
83
-
-
0036282759
-
Transport and local metabolism of budesonide and fluticasone propionate in a human bronchial epithelial cell line (Calu-3)
-
G. Borchard, M.L. Cassara, P.E. Roemele, B.I. Florea, and H.E. Junginger Transport and local metabolism of budesonide and fluticasone propionate in a human bronchial epithelial cell line (Calu-3) J. Pharm. Sci. 91 2002 1561 1567
-
(2002)
J. Pharm. Sci.
, vol.91
, pp. 1561-1567
-
-
Borchard, G.1
Cassara, M.L.2
Roemele, P.E.3
Florea, B.I.4
Junginger, H.E.5
-
84
-
-
0036220019
-
Contribution of efflux pump activity to the delivery of pulmonary therapeutics
-
K.O. Hamilton, M.A. Yazdanian, and K.L. Audus Contribution of efflux pump activity to the delivery of pulmonary therapeutics Curr. Drug Metab. 3 2002 1 12
-
(2002)
Curr. Drug Metab.
, vol.3
, pp. 1-12
-
-
Hamilton, K.O.1
Yazdanian, M.A.2
Audus, K.L.3
-
85
-
-
13544250625
-
Salbutamol is actively absorbed across human bronchial epithelial cell layers
-
C. Ehrhardt, C. Bies, C. Kneuer, U. Bakowsky, K.J. Kim, C.M. Lehr, Salbutamol is actively absorbed across human bronchial epithelial cell layers, Pulm. Pharmacol. Ther. 3 (2005) 165-170.
-
(2005)
Pulm. Pharmacol. Ther.
, vol.3
, pp. 165-170
-
-
Ehrhardt, C.1
Bies, C.2
Kneuer, C.3
Bakowsky, U.4
Kim, K.J.5
Lehr, C.M.6
-
86
-
-
0041331765
-
Effects of the permeability enhancers, tetradecylmaltoside and dimethyl-beta-cyclodextrin, on insulin movement across human bronchial epithelial cells (16HBE14o-)
-
F. Ahsan, J.J. Arnold, T. Yang, E. Meezan, E.M. Schwiebert, and D.J. Pillion Effects of the permeability enhancers, tetradecylmaltoside and dimethyl-beta-cyclodextrin, on insulin movement across human bronchial epithelial cells (16HBE14o-) Eur. J. Pharm. Sci. 20 2003 27 34
-
(2003)
Eur. J. Pharm. Sci.
, vol.20
, pp. 27-34
-
-
Ahsan, F.1
Arnold, J.J.2
Yang, T.3
Meezan, E.4
Schwiebert, E.M.5
Pillion, D.J.6
-
87
-
-
0035206717
-
Evidence of P-glycoprotein mediated apical to basolateral transport of flunisolide in human broncho-tracheal epithelial cells (Calu-3)
-
B.I. Florea, I.C. van der Sandt, S.M. Schrier, K. Kooiman, K. Deryckere, A.G. de Boer, H.E. Junginger, and G. Borchard Evidence of P-glycoprotein mediated apical to basolateral transport of flunisolide in human broncho-tracheal epithelial cells (Calu-3) Br. J. Pharmacol. 134 2001 1555 1563
-
(2001)
Br. J. Pharmacol.
, vol.134
, pp. 1555-1563
-
-
Florea, B.I.1
Van Der Sandt, I.C.2
Schrier, S.M.3
Kooiman, K.4
Deryckere, K.5
De Boer, A.G.6
Junginger, H.E.7
Borchard, G.8
-
88
-
-
20444398006
-
-
Thesis, Saarland University, Saarbrücken, Germany
-
S. Fuchs, Humane alveolare Epithelzellen in Primärkultur: Zellbiologische Charakterisierung, Transporteigenschaften und Transduktion mit retroviralen Vektoren zur Verlängerung der Lebensdauer, Thesis, Saarland University, Saarbrücken, Germany, 2003.
-
(2003)
Humane Alveolare Epithelzellen in Primärkultur: Zellbiologische Charakterisierung, Transporteigenschaften und Transduktion Mit Retroviralen Vektoren Zur Verlängerung der Lebensdauer
-
-
Fuchs, S.1
-
89
-
-
0037308144
-
Protein transport across the lung epithelial barrier
-
K.J. Kim, and A.B. Malik Protein transport across the lung epithelial barrier Am. J. Physiol. 284 2003 L247 L259
-
(2003)
Am. J. Physiol.
, vol.284
-
-
Kim, K.J.1
Malik, A.B.2
-
90
-
-
0027172392
-
Regulation of tight junction permeability by calcium chelators and cell cytoskeleton in rabbit tracheal epithelium
-
M. Bhat, D. Toledo-Velasquez, L. Wang, C.J. Malanga, J.K.H. Ma, and Y. Rojanasakul Regulation of tight junction permeability by calcium chelators and cell cytoskeleton in rabbit tracheal epithelium Pharm. Res. 10 1993 991 997
-
(1993)
Pharm. Res.
, vol.10
, pp. 991-997
-
-
Bhat, M.1
Toledo-Velasquez, D.2
Wang, L.3
Malanga, C.J.4
Ma, J.K.H.5
Rojanasakul, Y.6
-
91
-
-
0026666843
-
The transport barrier of epithelia: comparative study on membrane permeability and charge selectivity in rabbit
-
Y. Rojanasakul, L. Wang, M. Bhat, D.D. Glover, C.J. Malanga, and J.K.H. Ma The transport barrier of epithelia: comparative study on membrane permeability and charge selectivity in rabbit Pharm. Res. 9 1992 1029 1034
-
(1992)
Pharm. Res.
, vol.9
, pp. 1029-1034
-
-
Rojanasakul, Y.1
Wang, L.2
Bhat, M.3
Glover, D.D.4
Malanga, C.J.5
Ma, J.K.H.6
-
92
-
-
0020961251
-
Measurements of pulmonary epithelial permeability in vivo
-
R.M. Effros, G.R. Mason, Measurements of pulmonary epithelial permeability in vivo, Am. Rev. Respir. Dis. 127(1983) S59-S65.
-
(1983)
Am. Rev. Respir. Dis.
, vol.127
-
-
Effros, R.M.1
Mason, G.R.2
-
93
-
-
0034059951
-
Rates of protein transport across rat alveolar epithelial cell monolayers
-
Y. Matsukawa, H. Yamahara, F. Yamashita, V.H.L. Lee, E.D. Crandall, and K.J. Kim Rates of protein transport across rat alveolar epithelial cell monolayers J. Drug Target. 7 2000 335 342
-
(2000)
J. Drug Target.
, vol.7
, pp. 335-342
-
-
Matsukawa, Y.1
Yamahara, H.2
Yamashita, F.3
Lee, V.H.L.4
Crandall, E.D.5
Kim, K.J.6
-
94
-
-
0032459952
-
Cell lines of pulmonary and non-pulmonary origin as tools to study the effects of house dust mite proteinases on the regulation of epithelial permeability
-
H. Winton, H. Wan, M.B. Cannell, D.C. Gruenert, P.J. Thompson, D.R. Garrod, G.A. Stewart, and C. Robinson Cell lines of pulmonary and non-pulmonary origin as tools to study the effects of house dust mite proteinases on the regulation of epithelial permeability Clin. Exp. Allergy 28 1998 1273 1285
-
(1998)
Clin. Exp. Allergy
, vol.28
, pp. 1273-1285
-
-
Winton, H.1
Wan, H.2
Cannell, M.B.3
Gruenert, D.C.4
Thompson, P.J.5
Garrod, D.R.6
Stewart, G.A.7
Robinson, C.8
-
95
-
-
0032531145
-
Characterization of the A549 cell line as a type II pulmonary epithelial cell model for drug metabolism
-
K.A. Foster, C.G. Oster, M.M. Mayer, M.L. Avery, and K.L. Audus Characterization of the A549 cell line as a type II pulmonary epithelial cell model for drug metabolism Exp. Cell Res. 243 1998 359 366
-
(1998)
Exp. Cell Res.
, vol.243
, pp. 359-366
-
-
Foster, K.A.1
Oster, C.G.2
Mayer, M.M.3
Avery, M.L.4
Audus, K.L.5
-
96
-
-
0035460504
-
Expression of xenobiotic-metabolizing enzymes in human pulmonary tissue: possible role in susceptibility for ILD
-
J. Hukkanen, O. Pelkonen, and H. Raunio Expression of xenobiotic-metabolizing enzymes in human pulmonary tissue: possible role in susceptibility for ILD Eur. Respir. J. 32 2001 122s 126s
-
(2001)
Eur. Respir. J.
, vol.32
-
-
Hukkanen, J.1
Pelkonen, O.2
Raunio, H.3
-
97
-
-
2342663701
-
Benzene metabolism in human lung cell lines BEAS-2B and A549 and cells overexpressing CYP2F1
-
P.L. Sheets, G.S. Yost, and G.P. Carlson Benzene metabolism in human lung cell lines BEAS-2B and A549 and cells overexpressing CYP2F1 J. Biochem. Mol. Toxicol. 18 2004 92 99
-
(2004)
J. Biochem. Mol. Toxicol.
, vol.18
, pp. 92-99
-
-
Sheets, P.L.1
Yost, G.S.2
Carlson, G.P.3
-
98
-
-
0032077398
-
Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues
-
K. Mace, E.D. Bowman, P. Vautravers, P.G. Shields, C.C. Harris, and A.M. Pfeifer Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues Eur. J. Cancer 34 1998 914 920
-
(1998)
Eur. J. Cancer
, vol.34
, pp. 914-920
-
-
Mace, K.1
Bowman, E.D.2
Vautravers, P.3
Shields, P.G.4
Harris, C.C.5
Pfeifer, A.M.6
-
99
-
-
7044231565
-
Induction of drug-metabolizing enzymes and transporters in human bronchial epithelial cells by beclomethasone dipropionate
-
Y. Kuzuya, T. Adachi, H. Hara, A. Anan, K. Izuhara, and H. Nagai Induction of drug-metabolizing enzymes and transporters in human bronchial epithelial cells by beclomethasone dipropionate IUBMB Life 56 2004 355 359
-
(2004)
IUBMB Life
, vol.56
, pp. 355-359
-
-
Kuzuya, Y.1
Adachi, T.2
Hara, H.3
Anan, A.4
Izuhara, K.5
Nagai, H.6
-
100
-
-
0034605705
-
Characterization of the Calu-3 cell line as a tool to screen pulmonary drug delivery
-
K.A. Foster, M.L. Avery, M. Yazdanian, and K.L. Audus Characterization of the Calu-3 cell line as a tool to screen pulmonary drug delivery Int. J. Pharm. 208 2000 1 11
-
(2000)
Int. J. Pharm.
, vol.208
, pp. 1-11
-
-
Foster, K.A.1
Avery, M.L.2
Yazdanian, M.3
Audus, K.L.4
-
101
-
-
0033810470
-
A highly sensitive fluorescent microplate method for the determination of UDP-glucuronosyl transferase activity in tissues and placental cell lines
-
A.C. Collier, M.D. Tingle, J.A. Keelan, J.W. Paxton, and M.D. Mitchell A highly sensitive fluorescent microplate method for the determination of UDP-glucuronosyl transferase activity in tissues and placental cell lines Drug Metab. Dispos. 28 2000 1184 1186
-
(2000)
Drug Metab. Dispos.
, vol.28
, pp. 1184-1186
-
-
Collier, A.C.1
Tingle, M.D.2
Keelan, J.A.3
Paxton, J.W.4
Mitchell, M.D.5
-
102
-
-
0032964522
-
Temporal dependence of ectopeptidase expression in alveolar epithelial cell culture: implications for study of peptide absorption
-
B. Forbes, C.G. Wilson, and M. Gumbleton Temporal dependence of ectopeptidase expression in alveolar epithelial cell culture: implications for study of peptide absorption Int. J. Pharm. 180 1999 225 234
-
(1999)
Int. J. Pharm.
, vol.180
, pp. 225-234
-
-
Forbes, B.1
Wilson, C.G.2
Gumbleton, M.3
-
103
-
-
0028471137
-
Glucocorticoids do not alter peptidase expression in on a human bronchial epithelial cell line
-
D. Proud, M.C. Subauste, and P.E. Ward Glucocorticoids do not alter peptidase expression in on a human bronchial epithelial cell line Am. J. Respir. Cell Mol. Biol. 11 1994 57 65
-
(1994)
Am. J. Respir. Cell Mol. Biol.
, vol.11
, pp. 57-65
-
-
Proud, D.1
Subauste, M.C.2
Ward, P.E.3
-
104
-
-
4744368322
-
Metabolic cleavage of cell-penetrating peptides in ncontact with epithelial models: human calcitonin (hCT)-derived peptides Tat (47-57) and penetratin (43-58)
-
R. Trehin, H.M. Nielsen, H.G. Jahnke, A.G. Beck-Sickinger, and H. Merkle Metabolic cleavage of cell-penetrating peptides in ncontact with epithelial models: human calcitonin (hCT)-derived peptides Tat (47-57) and penetratin (43-58) Biochem. J. 382 2004 924 956
-
(2004)
Biochem. J.
, vol.382
, pp. 924-956
-
-
Trehin, R.1
Nielsen, H.M.2
Jahnke, H.G.3
Beck-Sickinger, A.G.4
Merkle, H.5
-
105
-
-
0033788563
-
In vitro toxicology of respirable Montserrat volcanic ash
-
M.R. Wilson, V. Stone, R.T. Cullen, A. Searl, R.L. Maynard, and K. Donaldson In vitro toxicology of respirable Montserrat volcanic ash Occup. Environ. Med. 57 2000 727 733
-
(2000)
Occup. Environ. Med.
, vol.57
, pp. 727-733
-
-
Wilson, M.R.1
Stone, V.2
Cullen, R.T.3
Searl, A.4
Maynard, R.L.5
Donaldson, K.6
-
106
-
-
4644249080
-
Cigarette smoke inhibits lipopolysaccharide-induced production of inflammatory cytokines by suppressing the activation of activator protein-1 in bronchial epithelial cells
-
M. Laan, S. Bozinovski, and G. Anderson Cigarette smoke inhibits lipopolysaccharide-induced production of inflammatory cytokines by suppressing the activation of activator protein-1 in bronchial epithelial cells J. Immunol. 173 2004 4164 4170
-
(2004)
J. Immunol.
, vol.173
, pp. 4164-4170
-
-
Laan, M.1
Bozinovski, S.2
Anderson, G.3
-
107
-
-
0035047944
-
Benzene-extracted components are important for the major activity of diesel exhaust particles - effect on interleukin-8 gene expression in human bronchial epithelial cells
-
S. Kawasaki, H. Takizawa, K. Takami, M. Desaki, H. Okazaki, T. Kasama, K. Kobayashi, K. Yamamoto, K. Nakahara, M. Tanaka, M. Sagai, and T. Ohtoshi Benzene-extracted components are important for the major activity of diesel exhaust particles - effect on interleukin-8 gene expression in human bronchial epithelial cells Am. J. Respir. Cell Mol. Biol. 24 2001 419 426
-
(2001)
Am. J. Respir. Cell Mol. Biol.
, vol.24
, pp. 419-426
-
-
Kawasaki, S.1
Takizawa, H.2
Takami, K.3
Desaki, M.4
Okazaki, H.5
Kasama, T.6
Kobayashi, K.7
Yamamoto, K.8
Nakahara, K.9
Tanaka, M.10
Sagai, M.11
Ohtoshi, T.12
-
108
-
-
0032819018
-
Preliminary investigations into the use of a human bronchial cell line (16HBE14o-) to screen for respiratory toxins in vitro
-
C. Westmoreland, T. Walker, J. Matthews, and J. Murdock Preliminary investigations into the use of a human bronchial cell line (16HBE14o-) to screen for respiratory toxins in vitro Toxicol. In Vitro 13 1999 761 764
-
(1999)
Toxicol. In Vitro
, vol.13
, pp. 761-764
-
-
Westmoreland, C.1
Walker, T.2
Matthews, J.3
Murdock, J.4
-
109
-
-
0033735533
-
Formulation of inhaled medicines: effect of delivery vehicle on immortalized epithelial cells
-
B. Forbes, N. Hashmi, G.P. Martin, and A.B. Lansley Formulation of inhaled medicines: effect of delivery vehicle on immortalized epithelial cells J. Aerosol. Med. 13 2000 281 288
-
(2000)
J. Aerosol. Med.
, vol.13
, pp. 281-288
-
-
Forbes, B.1
Hashmi, N.2
Martin, G.P.3
Lansley, A.B.4
-
110
-
-
20444403247
-
Pulmonary delivery of low molecular weight heparins
-
T.Z. Yang, F. Mustafa, S.H. Bai, and F. Ahsan Pulmonary delivery of low molecular weight heparins Pharm. Res. 21 2004 2009 2016
-
(2004)
Pharm. Res.
, vol.21
, pp. 2009-2016
-
-
Yang, T.Z.1
Mustafa, F.2
Bai, S.H.3
Ahsan, F.4
-
112
-
-
0028856079
-
Alveolar lining layer is thin and continuous: low-temperature scanning electron microscopy of rat lung
-
J. Bastacky, C.Y. Lee, J. Goerke, H. Koushafar, D. Yager, L. Kenaga, T.P. Speed, Y. Chen, and J.A. Clements Alveolar lining layer is thin and continuous: low-temperature scanning electron microscopy of rat lung J. Appl. Physiol. 79 1995 1615 1628
-
(1995)
J. Appl. Physiol.
, vol.79
, pp. 1615-1628
-
-
Bastacky, J.1
Lee, C.Y.2
Goerke, J.3
Koushafar, H.4
Yager, D.5
Kenaga, L.6
Speed, T.P.7
Chen, Y.8
Clements, J.A.9
-
114
-
-
0032961328
-
In vitro evaluation of microparticles and polymer gels for use as nasal platforms for protein delivery
-
C. Witschi, and R.J. Mrsny In vitro evaluation of microparticles and polymer gels for use as nasal platforms for protein delivery Pharm. Res. 16 1999 382 390
-
(1999)
Pharm. Res.
, vol.16
, pp. 382-390
-
-
Witschi, C.1
Mrsny, R.J.2
-
115
-
-
3242669006
-
Pulmonary delivery of deslorelin: large-porous PLGA particles and HPbetaCD complexes
-
K. Koushik, D.S. Dhanda, N.P. Cheruvu, and U.B. Kompella Pulmonary delivery of deslorelin: large-porous PLGA particles and HPbetaCD complexes Pharm. Res. 21 2004 1119 1126
-
(2004)
Pharm. Res.
, vol.21
, pp. 1119-1126
-
-
Koushik, K.1
Dhanda, D.S.2
Cheruvu, N.P.3
Kompella, U.B.4
-
116
-
-
2142695730
-
Incorporation of biodegradable nanoparticles into human airway epithelium cells-in vitro study of the suitability as a vehicle for drug or gene delivery in pulmonary diseases
-
M. Brzoska, K. Langer, C. Coester, S. Loitsch, T.O. Wagner, and C. Mallinckrodt Incorporation of biodegradable nanoparticles into human airway epithelium cells-in vitro study of the suitability as a vehicle for drug or gene delivery in pulmonary diseases Biochem. Biophys. Res. Commun. 318 2004 562 570
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.318
, pp. 562-570
-
-
Brzoska, M.1
Langer, K.2
Coester, C.3
Loitsch, S.4
Wagner, T.O.5
Mallinckrodt, C.6
-
117
-
-
0035140581
-
Microparticulate uptake mechanisms of in vitro cell culture models of the respiratory epithelium
-
K.A. Foster, M. Yazdanian, and K.L. Audus Microparticulate uptake mechanisms of in vitro cell culture models of the respiratory epithelium J. Pharm. Pharmacol. 53 2001 57 66
-
(2001)
J. Pharm. Pharmacol.
, vol.53
, pp. 57-66
-
-
Foster, K.A.1
Yazdanian, M.2
Audus, K.L.3
-
118
-
-
0036146377
-
An in vitro technique for evaluating inhaled nasal delivery systems
-
B. Forbes, S. Lim, G.P. Martin, and M.B. Brown An in vitro technique for evaluating inhaled nasal delivery systems STP Pharma. Sci. 12 2002 75 79
-
(2002)
STP Pharma. Sci.
, vol.12
, pp. 75-79
-
-
Forbes, B.1
Lim, S.2
Martin, G.P.3
Brown, M.B.4
-
119
-
-
3042791257
-
Delivery of therapeutic levels of heparin and low-molecular weight heparin through a pulmonary route
-
Y. Qi, G. Zhao, D. Liu, Z. Shriver, M. Sundaram, S. Sengupta, G. Ventataraman, R. Langer, and R. Sasisekharan Delivery of therapeutic levels of heparin and low-molecular weight heparin through a pulmonary route Proc. Natl Acad. Sci. 101 2004 9867 9872
-
(2004)
Proc. Natl Acad. Sci.
, vol.101
, pp. 9867-9872
-
-
Qi, Y.1
Zhao, G.2
Liu, D.3
Shriver, Z.4
Sundaram, M.5
Sengupta, S.6
Ventataraman, G.7
Langer, R.8
Sasisekharan, R.9
-
120
-
-
0142105943
-
Pulmonary absorption of insulin mediated by tetradecyl-beta-maltoside and dimethyl-beta-cyclodextrin
-
A. Hussain, T. Yang, A.A. Zaghloul, and F. Ahsan Pulmonary absorption of insulin mediated by tetradecyl-beta-maltoside and dimethyl-beta-cyclodextrin Pharm. Res. 20 2003 1551 1557
-
(2003)
Pharm. Res.
, vol.20
, pp. 1551-1557
-
-
Hussain, A.1
Yang, T.2
Zaghloul, A.A.3
Ahsan, F.4
-
121
-
-
20444378399
-
In vivo and in vitro characterization of novel microparticles based on hyaluronan and chitosan hydroglutamate
-
S.T. Lim, B. Forbes, G.P. Martin, and M.B. Brown In vivo and in vitro characterization of novel microparticles based on hyaluronan and chitosan hydroglutamate AAPS Pharma Sci Tech 2 2001 1 14
-
(2001)
AAPS Pharma Sci Tech
, vol.2
, pp. 1-14
-
-
Lim, S.T.1
Forbes, B.2
Martin, G.P.3
Brown, M.B.4
-
122
-
-
1842431573
-
Identification of an internalising peptide in differentiated Calu-3 cells by phage display technology; application to gene delivery to the airways
-
B.I. Florea, T.J. Molenaar, I. Bot, I.N. Michon, J. Kuiper, T.J. van Berkel, H.E. Junginger, E.A. Biessen, and G. Borchard Identification of an internalising peptide in differentiated Calu-3 cells by phage display technology; application to gene delivery to the airways J. Drug Target. 11 2003 383 390
-
(2003)
J. Drug Target.
, vol.11
, pp. 383-390
-
-
Florea, B.I.1
Molenaar, T.J.2
Bot, I.3
Michon, I.N.4
Kuiper, J.5
Van Berkel, T.J.6
Junginger, H.E.7
Biessen, E.A.8
Borchard, G.9
-
123
-
-
14644412792
-
Biodistribution study of phosphonolipids: a class of non-viral vectors efficient in mice lung-directed gene transfer
-
P. Delepine, C. Guillaume, T. Montier, J.C. Clement, J.J. Yaouanc, H. des Abbayes, F. Berthou, A Le Pape, and C. Ferec Biodistribution study of phosphonolipids: a class of non-viral vectors efficient in mice lung-directed gene transfer J. Gene Med. 5 2003 600 608
-
(2003)
J. Gene Med.
, vol.5
, pp. 600-608
-
-
Delepine, P.1
Guillaume, C.2
Montier, T.3
Clement, J.C.4
Yaouanc, J.J.5
Des Abbayes, H.6
Berthou, F.7
Le Pape, A.8
Ferec, C.9
-
124
-
-
0034099608
-
Tight junction properties of the immortalized human bronchial epithelial cell lines Calu-3 and 16HBE14o
-
H. Wan, H.L. Winton, C. Soeller, G.A. Stewart, P.J. Thompson, D.C. Gruenert, M.B. Cannell, D.R. Garrod, and C. Robinson Tight junction properties of the immortalized human bronchial epithelial cell lines Calu-3 and 16HBE14o- Eur. Respir. J. 15 2000 1058 1068
-
(2000)
Eur. Respir. J.
, vol.15
, pp. 1058-1068
-
-
Wan, H.1
Winton, H.L.2
Soeller, C.3
Stewart, G.A.4
Thompson, P.J.5
Gruenert, D.C.6
Cannell, M.B.7
Garrod, D.R.8
Robinson, C.9
-
125
-
-
0036321111
-
Drug absorption by the respiratory mucosa: cell culture models and particulate drug carriers
-
C. Ehrhardt, J. Fiegel, S. Fuchs, R. Abu-Dahab, U.F. Schaefer, J. Hanes, and C.M. Lehr Drug absorption by the respiratory mucosa: cell culture models and particulate drug carriers J. Aerosol. Med. 15 2002 131 139
-
(2002)
J. Aerosol. Med.
, vol.15
, pp. 131-139
-
-
Ehrhardt, C.1
Fiegel, J.2
Fuchs, S.3
Abu-Dahab, R.4
Schaefer, U.F.5
Hanes, J.6
Lehr, C.M.7
-
126
-
-
20444417674
-
-
Thesis, Saarland University, Saarbrücken, Germany
-
C. Ehrhardt, Characterisation of epithelial cell culture models of the lung for in vitro studies of pulmonary drug delivery, Thesis, Saarland University, Saarbrücken, Germany, 2003.
-
(2003)
Characterisation of Epithelial Cell Culture Models of the Lung for in Vitro Studies of Pulmonary Drug Delivery
-
-
Ehrhardt, C.1
-
127
-
-
0034605705
-
Characterization of the Calu-3 cell line as a tool to screen pulmonary drug delivery
-
K.A. Foster, M.L. Avery, M. Yazdanian, and K.L. Audus Characterization of the Calu-3 cell line as a tool to screen pulmonary drug delivery Int. J. Pharm. 208 2000 1 11
-
(2000)
Int. J. Pharm.
, vol.208
, pp. 1-11
-
-
Foster, K.A.1
Avery, M.L.2
Yazdanian, M.3
Audus, K.L.4
-
128
-
-
0030940316
-
Vectorial transcytosis of dimeric IgA by the Calu-3 human lung epithelial cell line: upregulation by IFN-gamma
-
S. Loman, J. Radl, H.M. Jansen, T.A. Out, and R. Lutter Vectorial transcytosis of dimeric IgA by the Calu-3 human lung epithelial cell line: upregulation by IFN-gamma Am. J. Physiol. 272 1997 L951 L958
-
(1997)
Am. J. Physiol.
, vol.272
-
-
Loman, S.1
Radl, J.2
Jansen, H.M.3
Out, T.A.4
Lutter, R.5
-
129
-
-
0028791564
-
Development and characterization of rabbit tracheal epithelial cell monolayer models for drug transport studies
-
N.R. Mathias, K.J. Kim, T.W. Robison, and V.H.L. Lee Development and characterization of rabbit tracheal epithelial cell monolayer models for drug transport studies Pharm. Res. 12 1995 1499 1505
-
(1995)
Pharm. Res.
, vol.12
, pp. 1499-1505
-
-
Mathias, N.R.1
Kim, K.J.2
Robison, T.W.3
Lee, V.H.L.4
-
130
-
-
0033638754
-
Evaluation of the Caco-2 monolayer as a model epithelium for iontophoretic transport
-
M. Leonard, E. Creed, D. Brayden, and A.W. Baird Evaluation of the Caco-2 monolayer as a model epithelium for iontophoretic transport Pharm. Res. 17 2000 1181 1188
-
(2000)
Pharm. Res.
, vol.17
, pp. 1181-1188
-
-
Leonard, M.1
Creed, E.2
Brayden, D.3
Baird, A.W.4
|