-
1
-
-
0026596913
-
Lymphocyte activation in bronchoalveolar lavage and peripheral blood in atopic asthma
-
Wilson, J. W., Djukanovic, R., Howarth, P. H., and Holgate, S. T. (1992) Lymphocyte activation in bronchoalveolar lavage and peripheral blood in atopic asthma. Am. Rev. Respir. Dis. 145, 958-960.
-
(1992)
Am. Rev. Respir. Dis.
, vol.145
, pp. 958-960
-
-
Wilson, J.W.1
Djukanovic, R.2
Howarth, P.H.3
Holgate, S.T.4
-
2
-
-
0026666718
-
Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage
-
Walker, C., Bode, E., Boer, L., Hansel, T. T., Blaser, K., and Virchow, J. C. Jr. (1992) Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage. Am. Rev. Respir. Dis. 146, 109-115.
-
(1992)
Am. Rev. Respir. Dis.
, vol.146
, pp. 109-115
-
-
Walker, C.1
Bode, E.2
Boer, L.3
Hansel, T.T.4
Blaser, K.5
Virchow Jr., J.C.6
-
3
-
-
0042500949
-
Pharmaceutical characteristics that influence the clinical efficacy of inhaled corticosteroids
-
Kelly, H. W. (2003) Pharmaceutical characteristics that influence the clinical efficacy of inhaled corticosteroids. Ann. Allergy Asthma Immunol. 91, 326-334.
-
(2003)
Ann. Allergy Asthma Immunol.
, vol.91
, pp. 326-334
-
-
Kelly, H.W.1
-
4
-
-
0031700453
-
Glucocorticoid insensitive asthma: A one year clinical follow up pilot study
-
Demoly, P., Jaffuel, D., Mathieu, M., Sahla, H., Godard, P., Michel, F.-B., and Bousquet, J. (1998) Glucocorticoid insensitive asthma: a one year clinical follow up pilot study. Thorax 53, 1063-1065.
-
(1998)
Thorax
, vol.53
, pp. 1063-1065
-
-
Demoly, P.1
Jaffuel, D.2
Mathieu, M.3
Sahla, H.4
Godard, P.5
Michel, F.-B.6
Bousquet, J.7
-
5
-
-
0034455751
-
Five patients with biochemical and/or clinical generalized glucocorticoid resistance without alterations in the glucocorticoid receptor gene
-
Huizenga, N. A. T. M., de Lange, P., Koper, J. W., de Herder, W. W., Abs, R., v. Kasteren, J. H. L. M., de Jong, F. H., and Lamberts, S. W. J. (2000) Five patients with biochemical and/or clinical generalized glucocorticoid resistance without alterations in the glucocorticoid receptor gene. J. Clin. Endocrinol. Metab. 85, 2076-2081.
-
(2000)
J. Clin. Endocrinol. Metab.
, vol.85
, pp. 2076-2081
-
-
Huizenga, N.A.T.M.1
De Lange, P.2
Koper, J.W.3
De Herder, W.W.4
Abs, R.5
Kasteren, V.J.H.L.M.6
De Jong, F.H.7
Lamberts, S.W.J.8
-
6
-
-
0023235866
-
Tissue-specific regulation of glucocorticoid receptor mRNA by dexamethasone
-
Kalinyak, J. E., Dorin, R. I., Huffman, A. R., and Perlman, A. J. (1987) Tissue-specific regulation of glucocorticoid receptor mRNA by dexamethasone. J. Biol. Chem. 262, 10441-10444.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 10441-10444
-
-
Kalinyak, J.E.1
Dorin, R.I.2
Huffman, A.R.3
Perlman, A.J.4
-
7
-
-
0024204439
-
Regulation of glucocorticoid receptor expression: Evidence for transcriptional and posttranslational mechanisms
-
Dong, Y., Poellinger, L., Gustafsson, J. A., and Okret, S. (1988) Regulation of glucocorticoid receptor expression: evidence for transcriptional and posttranslational mechanisms. Mol. Endocrinol. 2, 1256-1264.
-
(1988)
Mol. Endocrinol.
, vol.2
, pp. 1256-1264
-
-
Dong, Y.1
Poellinger, L.2
Gustafsson, J.A.3
Okret, S.4
-
8
-
-
0027242280
-
Combination IL-2 and IL-4 reduces glucocorticoid receptor-binding affinity and T cell response to glucocorticoids
-
Kam, J. C., Szefler, S. J., Surs, W., Sher, E. R., and Leung, D. Y. (1993) Combination IL-2 and IL-4 reduces glucocorticoid receptor-binding affinity and T cell response to glucocorticoids. J. Immunol. 151, 3460-3466.
-
(1993)
J. Immunol.
, vol.151
, pp. 3460-3466
-
-
Kam, J.C.1
Szefler, S.J.2
Surs, W.3
Sher, E.R.4
Leung, D.Y.5
-
9
-
-
0028472787
-
Chemical mutational analysis of the human glucocorticoid receptor cDNA in glucocorticoid-resistant bronchial asthma
-
Lane, S. J., Arm, J. P., Staynov, D. Z., and Lee, T. H. (1994) Chemical mutational analysis of the human glucocorticoid receptor cDNA in glucocorticoid-resistant bronchial asthma. Am. J. Respir. Cell Mol. Biol. 11, 42-48.
-
(1994)
Am. J. Respir. Cell Mol. Biol.
, vol.11
, pp. 42-48
-
-
Lane, S.J.1
Arm, J.P.2
Staynov, D.Z.3
Lee, T.H.4
-
10
-
-
0028881859
-
Abnormal glucocorticoid receptor-activator protein 1 interaction in steroid-resistant asthma
-
Adcock, I. M., Lane, S. J., Brown, C. R., Lee, T. H., and Barnes, P. J. (1995) Abnormal glucocorticoid receptor-activator protein 1 interaction in steroid-resistant asthma. J. Exp. Med. 182, 1951-1958.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1951-1958
-
-
Adcock, I.M.1
Lane, S.J.2
Brown, C.R.3
Lee, T.H.4
Barnes, P.J.5
-
11
-
-
0032949332
-
Molecular and physical mechanisms of first-pass extraction
-
Hall, S. D., Thummel, K. E., Watkins, P. B., Lown, K. S., Benet, L. Z., Paine, M. F., Mayo, R. R., Turgeon, D. K., Bailey, D. G., Fontana, R. J., et al. (1999) Molecular and physical mechanisms of first-pass extraction. Drug Metab. Dispos. 27, 161-166.
-
(1999)
Drug Metab. Dispos.
, vol.27
, pp. 161-166
-
-
Hall, S.D.1
Thummel, K.E.2
Watkins, P.B.3
Lown, K.S.4
Benet, L.Z.5
Paine, M.F.6
Mayo, R.R.7
Turgeon, D.K.8
Bailey, D.G.9
Fontana, R.J.10
-
12
-
-
0025108622
-
Metabolic activation of 4-ipomeanol in human lung, primary pulmonary carcinomas, and established human pulmonary carcinoma cell lines
-
McLemore, T. L., Litterst, C. L., Coudert, B. P., Liu, M. C., Hubbard, W. C., Adelberg, S., Czerwinski, M., McMahon, N. A., Eggleston, J. C., and Boyd, M. R. (1990) Metabolic activation of 4-ipomeanol in human lung, primary pulmonary carcinomas, and established human pulmonary carcinoma cell lines. J. Natl. Cancer Inst. 82, 1420-1426.
-
(1990)
J. Natl. Cancer Inst.
, vol.82
, pp. 1420-1426
-
-
McLemore, T.L.1
Litterst, C.L.2
Coudert, B.P.3
Liu, M.C.4
Hubbard, W.C.5
Adelberg, S.6
Czerwinski, M.7
McMahon, N.A.8
Eggleston, J.C.9
Boyd, M.R.10
-
13
-
-
0027361057
-
Main drug- and carcinogen-metabolizing enzyme systems in human non-small cell lung cancer and peritumoral tissues
-
Toussaint, C., Albin, N., Massaad, L., Grunenwald, D., Parise, O. Jr. Morizet, J., Gouyette, A., and Chabot, G. G. (1993) Main drug- and carcinogen-metabolizing enzyme systems in human non-small cell lung cancer and peritumoral tissues. Cancer Res. 53, 4608-4612.
-
(1993)
Cancer Res.
, vol.53
, pp. 4608-4612
-
-
Toussaint, C.1
Albin, N.2
Massaad, L.3
Grunenwald, D.4
Parise Jr., O.5
Morizet, J.6
Gouyette, A.7
Chabot, G.G.8
-
14
-
-
0033810470
-
A highly sensitive fluorescent microplate method for the determination of UDP-glucuronosyl transferase activity in tissues and placental cell lines
-
Collier, A. C., Tingle, M. D., Keelan, J. A., Paxton, J. W., and Mitchell, M. D. (2000) A highly sensitive fluorescent microplate method for the determination of UDP-glucuronosyl transferase activity in tissues and placental cell lines. Drug Metab. Dispos. 28, 1184-1186.
-
(2000)
Drug Metab. Dispos.
, vol.28
, pp. 1184-1186
-
-
Collier, A.C.1
Tingle, M.D.2
Keelan, J.A.3
Paxton, J.W.4
Mitchell, M.D.5
-
15
-
-
0033783035
-
O-glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanol (NNAL) by human UDP-glucuronosyltransferases 2B7 and 1A9
-
Ren, Q., Murphy, S. E., Zheng, Z., and Lazarus, P. (2000) O-glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanol (NNAL) by human UDP-glucuronosyltransferases 2B7 and 1A9. Drug Metab. Dispos. 28, 1352-1360.
-
(2000)
Drug Metab. Dispos.
, vol.28
, pp. 1352-1360
-
-
Ren, Q.1
Murphy, S.E.2
Zheng, Z.3
Lazarus, P.4
-
16
-
-
0024279163
-
The multidrug transporter, a double-edged sword
-
Gottesman, M. M., and Pastan, I. (1988) The multidrug transporter, a double-edged sword. J. Biol. Chem. 263, 12163-12166.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 12163-12166
-
-
Gottesman, M.M.1
Pastan, I.2
-
17
-
-
0026487058
-
Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone
-
Ueda, K., Okamura, N., Hirai, M., Tanigawara, Y., Saeki, T., Kioka, N., Komano, T., and Hori, R. (1992) Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone. J. Biol. Chem. 267, 24248-24252.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 24248-24252
-
-
Ueda, K.1
Okamura, N.2
Hirai, M.3
Tanigawara, Y.4
Saeki, T.5
Kioka, N.6
Komano, T.7
Hori, R.8
-
18
-
-
0034892459
-
Multidrug resistance-associated protein-1 functional activity in Calu-3 cells
-
Hamilton, K. O., Topp, E., Makagiansar, I., Siahaan, T., Yazdanian, M., and Audus, K. L. (2001) Multidrug resistance-associated protein-1 functional activity in Calu-3 cells. J. Pharmacol. Exp. Ther. 298, 1199-1205.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.298
, pp. 1199-1205
-
-
Hamilton, K.O.1
Topp, E.2
Makagiansar, I.3
Siahaan, T.4
Yazdanian, M.5
Audus, K.L.6
-
19
-
-
0035032962
-
P-glycoprotein efflux pump expression and activity in Calu-3 cells
-
Hamilton, K. O., Backström, G., Yazdanian, M. A., and Audus, K. L. (2001) P-glycoprotein efflux pump expression and activity in Calu-3 cells. J. Pharm. Sci. 90, 647-658.
-
(2001)
J. Pharm. Sci.
, vol.90
, pp. 647-658
-
-
Hamilton, K.O.1
Backström, G.2
Yazdanian, M.A.3
Audus, K.L.4
-
20
-
-
0031178547
-
Quantitative RT-PCR measurement of cytochromes p450 1A1, 1B1, and 2B7, microsomal epoxide hydrolase, and NADPH oxidoreductase expression in lung cells of smokers and nonsmokers
-
Willey, J. C., Coy, E. L., Frampton, M. W., Torres, A., Apostolakos, M. J., Hoehn, G., Schuermann, W. H., Thilly, W. G., Olson, D. E., Hammersley, J. R., et al. (1997) Quantitative RT-PCR measurement of cytochromes p450 1A1, 1B1, and 2B7, microsomal epoxide hydrolase, and NADPH oxidoreductase expression in lung cells of smokers and nonsmokers. Am. J. Respir. Cell Mol. Biol. 17, 114-124.
-
(1997)
Am. J. Respir. Cell Mol. Biol.
, vol.17
, pp. 114-124
-
-
Willey, J.C.1
Coy, E.L.2
Frampton, M.W.3
Torres, A.4
Apostolakos, M.J.5
Hoehn, G.6
Schuermann, W.H.7
Thilly, W.G.8
Olson, D.E.9
Hammersley, J.R.10
-
21
-
-
0037100099
-
Presence of phenol UDP-glucuronosyltransferase in bovine alveolar macrophages and bronchial epithelial cells
-
Yamashiki, N., Yokota, H., Sakamoto, M., and Yuasa, A. (2002) Presence of phenol UDP-glucuronosyltransferase in bovine alveolar macrophages and bronchial epithelial cells. Toxicology 176, 221-227.
-
(2002)
Toxicology
, vol.176
, pp. 221-227
-
-
Yamashiki, N.1
Yokota, H.2
Sakamoto, M.3
Yuasa, A.4
-
22
-
-
12444302842
-
16HBE14o-human bronchial epithelial cell layers express P-glycoprotein, lung resistance-related protein, and caveolin-1
-
Ehrhardt, C., Kneuer, C., Laue, M., Schaefer, U. F., Kim, K.-J., and Lehr, C-M. (2003) 16HBE14o-human bronchial epithelial cell layers express P-glycoprotein, lung resistance-related protein, and caveolin-1. Pharm. Res. 20, 545-551.
-
(2003)
Pharm. Res.
, vol.20
, pp. 545-551
-
-
Ehrhardt, C.1
Kneuer, C.2
Laue, M.3
Schaefer, U.F.4
Kim, K.-J.5
Lehr, C.-M.6
-
23
-
-
0035813007
-
Expression of MRP1 and related transporters in human lung cells in culture
-
Lehmann, T., Köhler, C., Weidauer, E., Taege, C., and Foth, H. (2001) Expression of MRP1 and related transporters in human lung cells in culture. Toxicology 167, 59-72.
-
(2001)
Toxicology
, vol.167
, pp. 59-72
-
-
Lehmann, T.1
Köhler, C.2
Weidauer, E.3
Taege, C.4
Foth, H.5
-
24
-
-
0343526338
-
Induction of cytochrome P450 (CYP)1A1, CYP1A2, and CYP3A4 but not of CYP2C9, CYP2C19, multidrug resistance (MDR-1) and multidrug resistance associated protein (MRP-1) by prototypical inducers in human hepatocytes
-
Runge, D., Köhler, C., Kostrubsky, V. E., Jäger, D., Lehmann, T., Runge, D. M., May, U., Stolz, D. B., Strom, S. C., Fleig, W. E., et al. (2000) Induction of cytochrome P450 (CYP)1A1, CYP1A2, and CYP3A4 but not of CYP2C9, CYP2C19, multidrug resistance (MDR-1) and multidrug resistance associated protein (MRP-1) by prototypical inducers in human hepatocytes. Biochem. Biophys. Res. Commun. 273, 333-341.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.273
, pp. 333-341
-
-
Runge, D.1
Köhler, C.2
Kostrubsky, V.E.3
Jäger, D.4
Lehmann, T.5
Runge, D.M.6
May, U.7
Stolz, D.B.8
Strom, S.C.9
Fleig, W.E.10
-
25
-
-
0028958395
-
Phenotypic variability in induction of P-glycoprotein mRNA by aromatic hydrocarbons in primary human hepatocytes
-
Schuetz, E. G., Schuetz, J. D., Thompson, M. T., Fisher, R. A., Madariage, J. R., and Strom, S. C. (1995) Phenotypic variability in induction of P-glycoprotein mRNA by aromatic hydrocarbons in primary human hepatocytes. Mol. Carcinog. 12, 61-65.
-
(1995)
Mol. Carcinog.
, vol.12
, pp. 61-65
-
-
Schuetz, E.G.1
Schuetz, J.D.2
Thompson, M.T.3
Fisher, R.A.4
Madariage, J.R.5
Strom, S.C.6
-
26
-
-
0036176692
-
Increase in rat liver UDP-glucuronosyltransferase mRNA by microsomal enzyme inducers that enhance thyroid hormone glucuronidation
-
Vansell, N. R., and Klaassen, C. D. (2002) Increase in rat liver UDP-glucuronosyltransferase mRNA by microsomal enzyme inducers that enhance thyroid hormone glucuronidation. Drug Metab. Dispos. 30, 240-246.
-
(2002)
Drug Metab. Dispos.
, vol.30
, pp. 240-246
-
-
Vansell, N.R.1
Klaassen, C.D.2
-
27
-
-
0034695410
-
Isolation and characterization of the human UGT2B15 gene, localized within a cluster of UGT2B genes and pseudogenes on chromosome 4
-
Turgeon, D., Carrier, J. S., Levesque, E., Beatty, B. G., Belanger, A., and Hum, D. W. (2000) Isolation and characterization of the human UGT2B15 gene, localized within a cluster of UGT2B genes and pseudogenes on chromosome 4. J. Mol. Biol. 295, 489-504.
-
(2000)
J. Mol. Biol.
, vol.295
, pp. 489-504
-
-
Turgeon, D.1
Carrier, J.S.2
Levesque, E.3
Beatty, B.G.4
Belanger, A.5
Hum, D.W.6
-
28
-
-
0038824200
-
Regulation of UDP glucuronosyltransferase genes
-
Mackenzie, P. I., Gregory, P. A., Gardner-Stephen, D. A., Lewinsky, R. H., Jorgensen, B. R., Nishiyama, T., Xie, W., and Randominska-Pandya, A. (2003) Regulation of UDP glucuronosyltransferase genes. Curr. Drug Metab. 4, 249-257.
-
(2003)
Curr. Drug Metab.
, vol.4
, pp. 249-257
-
-
Mackenzie, P.I.1
Gregory, P.A.2
Gardner-Stephen, D.A.3
Lewinsky, R.H.4
Jorgensen, B.R.5
Nishiyama, T.6
Xie, W.7
Randominska-Pandya, A.8
-
29
-
-
0036490686
-
Glucocorticoids induced the production and gene expression of IL-1α though AP-1 and partially NF-κB activation in murine epidermal cells
-
Awad, S., Yokozeki, H., Miyazaki, Y., Igawa, K., Minatohara, K., Satoh, T., and Nishioka, K. (2002) Glucocorticoids induced the production and gene expression of IL-1α though AP-1 and partially NF-κB activation in murine epidermal cells. J. Med. Dent. Sci. 49, 27-35.
-
(2002)
J. Med. Dent. Sci.
, vol.49
, pp. 27-35
-
-
Awad, S.1
Yokozeki, H.2
Miyazaki, Y.3
Igawa, K.4
Minatohara, K.5
Satoh, T.6
Nishioka, K.7
-
31
-
-
0036200949
-
Inhibitors of ATP-binding cassette transporters suppress interleukin-12 p40 production and major histocompatibility complex II up-regulation in macrophages
-
Haskó, G., Deitch, E. A., Németh, Z. H., Kuhel, D. G., and Szabó, C. (2002) Inhibitors of ATP-binding cassette transporters suppress interleukin-12 p40 production and major histocompatibility complex II up-regulation in macrophages. J. Pharmacol. Exp. Ther. 301, 103-110.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.301
, pp. 103-110
-
-
Haskó, G.1
Deitch, E.A.2
Németh, Z.H.3
Kuhel, D.G.4
Szabó, C.5
-
33
-
-
20244386956
-
Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein
-
Wijnholds, J., Evers, R., van Leusden, M. R., Mol, C. A., Zaman, G. J., Mayer, U., Beijnen, J. H., van der Valk, M., Krimpenfort, P., and Borst, P. (1997) Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein. Nat. Med. 3, 1275-1279.
-
(1997)
Nat. Med.
, vol.3
, pp. 1275-1279
-
-
Wijnholds, J.1
Evers, R.2
Van Leusden, M.R.3
Mol, C.A.4
Zaman, G.J.5
Mayer, U.6
Beijnen, J.H.7
Van Der Valk, M.8
Krimpenfort, P.9
Borst, P.10
-
34
-
-
0042812465
-
4 in bronchial epithelial cells
-
4 in bronchial epithelial cells. Eur. Respir. J. 22, 35-42.
-
(2003)
Eur. Respir. J.
, vol.22
, pp. 35-42
-
-
Zaitsu, M.1
Hamasaki, Y.2
Tsuji, K.3
Matsuo, M.4
Fujita, I.5
Aoki, Y.6
Ishii, E.7
Kohashi, O.8
|