Protein transport across the lung epithelial barrier

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 284, Issue 2 28-2, 2003, Pages

  Kim, Kwang Jin ^a   Malik, Asrar B ^b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF ILLINOIS   (United States)

Author keywords

Albumin; Alveolar epithelial cells; Immunoglobulin G; Secretory component

Indexed keywords

ALBUMIN; ALBUMIN BINDING PROTEIN; BINDING PROTEIN; CERULOPLASMIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G; IMMUNOGLOBULIN RECEPTOR; TRANSFERRIN; UNCLASSIFIED DRUG;

ANIMAL CELL; CAVEOLA; CELL CULTURE; COATED PIT; COATED VESICLE; CONCENTRATION RESPONSE; EPITHELIUM CELL; HOMEOSTASIS; HUMAN; HUMAN CELL; INFLAMMATION; INTERNALIZATION; LUNG ALVEOLUS CELL; LUNG ALVEOLUS CELL TYPE 1; LUNG ALVEOLUS EPITHELIUM; LUNG EDEMA; LUNG FLUID; LUNG INJURY; MEMBRANE PERMEABILITY; MORPHOLOGICAL TRAIT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROCESS MODEL; PROTEIN TRANSPORT; RAT; RECEPTOR BINDING; REGULATORY MECHANISM; REVIEW; TRANSCYTOSIS; TRANSPORT KINETICS;

EID: 0037308144     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00235.2002     Document Type: Review

References (126)

1. Agerberth B, Grunewald J, Castanos-Velez E, Olsson B, Jornvall H, Wigzell H, Eklund A, and Gudmundsson GH. Antibacterial components in bronchoalveolar lavage fluid from healthy individuals and sarcoidosis patients. Am J Respir Crit Care Med 160: 283-290, 1999.
2. Apodaca G. Endocytic traffic in polarized epithelial cells: role of the actin and microtubule cytoskeleton. Traffic 2: 149-159, 2001.
3. Bachofen A and Weibel ER. Alterations of the gas exchange apparatus in adult respiratory insufficiency associated with septicemia. Am Rev Respir Dis 116: 589-615, 1977.
4. Barrowcliffe MP, Morice A, Jones JG, and Sever PS. Pulmonary clearance of vasoactive intestinal peptide. Thorax 41: 88-93, 1986.
5. Bensch KG, Dominguez E, and Liebow AA. Absorption of intact protein molecules across the pulmonary air-tissue barrier. Science 157: 1204-1206, 1967.
6. Berthiaume Y, Albertine KH, Grady M, Fick G, and Matthay MA. Protein clearance from the air spaces and lungs of unanesthetized sheep over 144 h. J Appl Physiol 67: 1887-1897, 1989.
7. Berthiaume Y, Broaddus VC, Gropper MA, Tanita T, and Matthay MA. Alveolar liquid and protein clearance from normal dog lungs. J Appl Physiol 65: 585-593, 1988.
8. Berthiaume Y, Staub NC, and Matthay MA. β-Adrenergic agonists increase lung liquid clearance in anesthetized sheep. J Clin Invest 79: 335-343, 1987.
9. Bignon J, Chahinian P, Feldmann G, and Sapin C. Ultrastructural immunoperoxidase demonstration of autologous albumin in the alveolar capillary membrane and in the alveolar lining material in normal rats. J Cell Biol 64: 503-509, 1975.
10. Bignon J, Jaurand MC, Pinchon MC, Sapin C, and Warnet JM. Immunoelectron microscopic and immunochemical demonstrations of serum proteins in the alveolar lining material of the rat lung. Am Rev Respir Dis 113: 109-120, 1976.
11. Bomsel M, Prydz K, Parton RG, Gruenberg J, and Simons K. Endocytosis in filter-grown Madin-Darby canine kidney cells. J Cell Biol 109: 3243-3258, 1989.
12. Borok Z, Li X, Fernandes VF, Zhou B, Ann DK, and Crandall ED. Differential regulation of rat aquaporin-5 promoter/enhancer activities in lung and salivary epithelial cells. J Biol Chem 275: 26507-26514, 2000.
13. Borok Z, Lubman RL, Danto SI, Zhang XL, Zabski SM, King LS, Lee DM, Agre P, and Crandall ED. Keratinocyte growth factor modulates alveolar epithelial cell phenotype in vitro: expression of aquaporin 5. Am J Respir Cell Mol Biol 18: 554-561, 1998.
14. Borvak J, Richardson J, Medesan C, Antohe F, Radu C, Simionescu M, Ghetie V, and Ward ES. Functional expression of the MHC class I-related receptor, FcRn, in endothelial cells of mice. Int Immunol 10: 1289-1298, 1998.
15. Braley JF, Dawson CA, Moore VL, and Cozzini BO. Absorption of inhaled antigen into the circulation of isolated lungs from normal and immunized rabbits. J Clin Invest 61: 1240-1246, 1978.
16. Campbell L, Hollins AJ, Al-Eid A, Newman GR, von Ruhland C, and Gumbleton M. Caveolin-1 expression and caveolae biogenesis during cell transdifferentiation in lung alveolar epithelial primary cultures. Biochem Biophys Res Commun 262: 744-751, 1999.
17. Cantey JR and Hand WL. Cell-mediated immunity after bacterial infection of the lower respiratory tract. J Clin Invest 54: 1125-1134, 1974.
18. Carlson RW, Schaeffer RC, Michaels SG, and Weil MH. Pulmonary edema following intracranial hemorrhage. Chest 75: 731-734, 1979.
19. Cheek JM, Evans MJ, and Crandall ED. Type I cell-like morphology in tight alveolar epithelial monolayers. Exp Cell Res 184: 375-387, 1989.
20. Cheek JM, Kim KJ, and Crandall ED. Tight monolayers of rat alveolar epithelial cells: bioelectric properties and active sodium transport. Am J Physiol Cell Physiol 256: C688-C693, 1989.
21. Clark JG, Milberg JA, Steinberg KP, and Hudson LD. Elevated lavage levels of N-terminal peptide of type III procollagen are associated with increased fatality in adult respiratory distress syndrome. Chest 105: 126S-127S, 1994.
22. Corrin B. Phagocytic potential of pulmonary alveolar epithelium with particular reference to surfact metabolism. Thorax 25: 110-115, 1970.
23. Danto SI, Zabski SM, and Crandall ED. Reactivity of alveolar epithelial cells in primary culture with type I cell monoclonal antibodies. Am J Respir Cell Mol Biol 6: 296-306, 1992.
24. Deftos LJ, Nolan JJ, Seely BL, Clopton PL, Cote GJ, Whitham CL, Florek LJ, Christensen TA, and Hill MR. Intrapulmonary drug delivery of salmon calcitonin. Calcif Tissue Int 61: 345-347, 1997.
25. Delaeroix DL, Malburny GN, and Vaerman JP. Hepatobiliary transport of plasma IgA in the mouse: contribution to clearance of intravascular IgA. Eur J Immunol 15: 893-899, 1985.
26. 2-Macroglobulin, monomeric and polymeric immunoglobulin A, and immunoglobulin M in bronchoalveolar lavage. Am Rev Respir Dis 132: 829-835, 1985.
27. Dickinson BL, Badizadegan K, Wu Z, Ahouse JC, Zhu X, Simister NE, Blumberg RS, and Lencer WI. Bidirectional FcRn-dependent IgG transport in a polarized human intestinal epithelial cell line. J Clin Invest 104: 903-911, 1999.
28. Dobbs LG, Williams MC, and Brandt AE. Changes in biochemical characteristics and pattern of lectin binding of alveolar type II cells with time in culture. Biochim Biophys Acta 846: 155-166, 1985.
29. Dobbs LG, Williams MC, and Gonzalez R. Monoclonal antibodies specific to apical surfaces of rat alveolar type I cells bind to surfaces of cultured, but not freshly isolated, type II cells. Biochim Biophys Acta 970: 146-156, 1988.
30. Drab M, Verkade P, Elger M, Kasper M, Lohn M, Lauterbach B, Menne J, Lindschau C, Mende F, Luft FC, Schedl A, Haller H, and Kurzchalia TV. Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice. Science 293: 2449-2452, 2001.
31. Dranoff G, Crawford AD, Sadelain M, Ream B, Rashid A, Bronson RT, Dickersin GR, Bachurski CJ, Mark EL, Whitsett JA, and Mulligan RC. Involvement of granulocytemacrophage colony-stimulating factor in pulmonary homeostasis. Science 264: 713-716, 1994.
32. Dranoff G and Mulligan RC. Activities of granulocyte-macrophage colony-stimulating factor revealed by gene transfer and gene knockout studies. Stem Cells 12, Suppl 1: 173-182; discussion 182-184, 1994.
33. Drinker CK and Hardenbergh E. Absorption from the pulmonary alveoli. J Exp Med 86: 7-18, 1947.
34. Duits LA, Langermans JA, Paltansing S, van der Straaten T, Vervenne RA, Frost PA, Hiemstra PS, Thomas AW, and Nibbering PH. Expression of beta-defensin-1 in chimpanzee (Pan troglodytes) airways. J Med Primatol 29: 318-323, 2000.
35. Effros RM and Mason GR. Measurements of pulmonary epithelial permeability in vivo. Am Rev Respir Dis 127: S59-S65, 1983.
36. Elbert KJ, Okamoto CT, Lee VHL, Lehr CM, Crandall ED, and Kim KJ. Polymeric immunoglobulin receptors (pIgR) in rat alveolar epithelial cell monolayers (Abstract). FASEB J 10: A350, 1996.
37. Ellinger I, Schwab M, Stefanescu A, Hunziker W, and Fuchs R. IgG transport across trophoblast-derived BeWo cells: a model system to study IgG transport in the placenta. Eur J Immunol 29: 733-744, 1999.
38. Fandy TE, Lee VHL, Ann DK, Crandall ED, and Kim KJ. Expression of α- and β-subunit mRNA for FcRn in primary rat alveolar epithelial cell (AEC) monolayers (Abstract). Am J Respir Crit Care Med 165: A75, 2002.
39. Fandy TE, Lee VHL, Crandall ED, and Kim KJ. Transport characteristics of immunoglobulin G (IgG) across rat alveolar epithelial cell monolayers (Abstract). Am J Respir Crit Care Med 163: A572, 2001.
40. Fein A, Grossman RF, Jones JG, Overland E, Pitts L, Murray JF, and Staub NC. The value of edema fluid protein measurement in patients with pulmonary edema. Am J Med 67: 32-38, 1979.
41. Folkesson HG, Matthay MA, Westrom BR, Kim KJ, Karlsson BW, and Hastings RH. Alveolar epithelial clearance of protein. J Appl Physiol 80: 1431-1445, 1996.
42. Folkesson HG, Westrom BR, and Karlsson BW. Permeability of the respiratory tract to different-sized macromolecules after intratracheal instillation in young and adult rats. Acta Physiol Scand 139: 347-354, 1990.
43. Folkesson HG, Westrom BR, Pierzynowski SG, and Karlsson BW. Lung to blood passage of different-sized molecules during lung inflammation in the rat. J Appl Physiol 71: 1106-1111, 1991.
44. Folkesson HG, Westrom BR, Pierzynowski SG, Svendsen J, and Karlsson BW. Lung to blood passage of albumin and a nonapeptide after intratracheal instillation in the young developing pig. Acta Physiol Scand 147: 173-178, 1993.
45. Gee MH and Staub NC. Role of bulk fluid flow in protein permeability of the dog lung alveolar membrane. J Appl Physiol 42: 144-149, 1977.
46. Gelb AF and Klein E. Hemodynamic and alveolar protein studies in noncardiac pulmonary edema. Am Rev Respir Dis 114: 831-835, 1976.
47. Gonzalez-Crussi F and Boston RW. The absorptive function of the neonatal lung. Ultrastructural study of horseradish peroxidase uptake at the onset of ventilation. Lab Invest 26: 114-121, 1972.
48. Goodale RL, Goetzman B, and Visscher MB. Hypoxia and iodoacetic acid and alveolocapillary barrier permeability to albumin. Am J Physiol 219: 1226-1230, 1970.
49. Goodman MR, Link DW, Brown WR, and Nakane PK. Ultrastructural evidence of transport of secretory IgA across bronchial epithelium. Am Rev Respir Dis 123: 115-119, 1981.
50. Gorin AB and Stewart PA. Differential permeability of endothelial and epithelial barriers to albumin flux. J Appl Physiol 47: 1315-1324, 1979.
51. Haimoto H, Nagura H, Imaizumi M, Watanabe K, and Iijima S. Immunoelectronmicroscopic study on the transport of secretory IgA in the lower respiratory tract and alveoli. Virchows Arch 404: 369-380, 1984.
52. Hastings RH, Grady M, Sakuma T, and Matthay MA. Clearance of different-sized proteins from the alveolar space in humans and rabbits. J Appl Physiol 73: 1310-1316, 1992.
53. Hastings RH and Kim KJ. Alveolar protein clearance. In: Pulmonary Edema, edited by Matthay MA and Ingbar DH. New York: Dekker, 1998, p. 549-574.
54. Heppleston AG and Young AE. Uptake of inert particulate matter by alveolar cells: an ultrastructural study. J Pathol 111: 159-164, 1973.
55. Holter JF, Weiland JE, Pacht ER, Gadek JE, and Davis WB. Protein permeability in the adult respiratory distress syndrome. Loss of size selectivity of the alveolar epithelium. J Clin Invest 78: 1513-1522, 1986.
56. Honda Y, Takahashi H, Shijubo N, Kuroki Y, and Akino T. Surfactant protein-A concentration in bronchoalveolar lavage fluids of patients with pulmonary alveolar proteinosis. Chest 103: 496-499, 1993.
57. Huffinan JA, Hull WM, Dranoff G, Mulligan RC, and Whitsett JA. Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice. J Clin Invest 97: 649-655, 1996.
58. Ichimura T. [Transcytosis of immunoglobulin IgG]. Kaibogaku Zasshi 73: 595-602, 1998.
59. Jayr C and Matthay MA. Alveolar and lung liquid clearance in the absence of pulmonary blood flow in sheep. J Appl Physiol 71: 1679-1687, 1991.
60. Jia HP, Mills JN, Barahmand-Pour F, Nishimura D, Mallampali RK, Wang G, Wiles K, Tack BF, Bevins CL, and McCray PB. Molecular cloning and characterization of rat genes encoding homologues of human beta-defensins. Infect Immun 67: 4827-4833, 1999.
61. John TA, Vogel SM, Minshall RD, Ridge K, Tiruppathi C, and Malik AB. Evidence for the role of alveolar epithelial gp60 in active transalveolar albumin transport in the rat lung. J Physiol 533: 547-559, 2001.
62. Johnson LG, Cheng PW, and Boucher RC. Albumin absorption by canine bronchial epithelium. J Appl Physiol 66: 2772-2777, 1989.
63. Karrer HE. Electron microscopic study of the phagocytosis process in lung. J Biophys Biochem Cytol 7: 357-365, 1960.
64. Kasper M, Reimann T, Hempel U, Wenzel KW, Bierhaus A, Schuh D, Dimmer V, Haroske G, and Muller M. Loss of caveolin expression in type I pneumocytes as an indicator of subcellular alterations during lung fibrogenesis. Histochem Cell Biol 109: 41-48, 1998.
65. - fluxes to net ion transport by alveolar epithelium. Respir Physiol 85: 245-256, 1991.
66. Kim KJ, Rattan V, Oh P, Schnitzer JE, Kalra VK, and Crandall ED. Specific albumin-binding protein in alveolar epithelial cell monolayers (Abstract). Am J Respir Crit Care Med 151: A190, 1995.
67. Kobashi Y and Manabe T. The fibrosing process in so-called organized diffuse alveolar damage. An immunohistochemical study of the change from hyaline membrane to membranous fibrosis. Virchows Arch 422: 47-52, 1993.
68. Kristoffersen EK. Human placental Fc gamma-binding proteins in the maternofetal transfer of IgG. APMIS Suppl 64: 5-36, 1996.
69. Kumpel BM and Sooranna SR. Transcytosis of IgG anti-D by human term trophoblast cells in culture. Transfus Med 6: 115-120, 1996.
70. Lauweryns JM and Baert JH. Alveolar clearance and the role of the pulmonary lymphatics. Am Rev Respir Dis 115: 625-683, 1977.
71. Ma L, Matsukawa Y, Okamoto CT, Woo WH, Zhou HY, Crandall ED, and Kim KJ. Asymmetric fluxes of dimeric immunoglobulin A (dIgA) across rat alveolar epithelial cell monolayers (Abstract). Am J Respir Crit Care Med 159: A181, 1999.
72. Mackersie RC and Durelle J. Differential clearance of colloid and crystalloid solutions from the lung. J Trauma 35: 448-453, 1993.
73. Martin TR, Pistorese BP, Chi EY, Goodman RB, and Matthay MA. Effects of leukotriene B4 in the human lung. Recruitment of neutrophils into the alveolar spaces without a change in protein permeability. J Clin Invest 84: 1609-1619, 1989.
74. Matsukawa Y, Lee VH, Crandall ED, and Kim KJ. Size-dependent dextran transport across rat alveolar epithelial cell monolayers. J Pharm Sci 86: 305-309, 1997.
75. Matsukawa Y, Yamahara H, Lee VH, Crandall ED, and Kim KJ. Horseradish peroxidase transport across rat alveolar epithelial cell monolayers. Pharm Res 13: 1331-1335, 1996.
76. Matsukawa Y, Yamahara H, Yamashita F, Lee VH, Crandall ED, and Kim KJ. Rates of protein transport across rat alveolar epithelial cell monolayers. J Drug Target 7: 335-342, 2000.
77. Matthay MA. Resolution of pulmonary edema. Mechanisms of liquid, protein, and cellular clearance from the lung. Clin Chest Med 6: 521-545, 1985.
78. Matthay MA, Landolt CC, and Staub NC. Differential liquid and protein clearance from the alveoli of anesthetized sheep. J Appl Physiol 53: 96-104, 1982.
79. Matthay MA and Wiener-Kronish JP. Intact epithelial barrier function is critical for the resolution of alveolar edema in humans. Am Rev Respir Dis 142: 1250-1257, 1990.
80. McCarthy KM, Yoong Y, and Simister NE. Bidirectional transcytosis of IgG by the rat neonatal Fc receptor expressed in a rat kidney cell line: a system to study protein transport across epithelia. J Cell Sci 113: 1277-1285, 2000.
81. Merrill WW, Goodenberger D, Strober W, Matthay RA, Naegel GP, and Reynolds HY. Free secretory component and other proteins in human lung lavage. Am Rev Respir Dis 122: 156-161, 1980.
82. Minshall RD, Tiruppathi C, Vogel SM, and Malik AB. Vesicle formation and trafficking in endothelial cells and regulation of endothelial barrier function. Histochem Cell Biol 117: 105-112, 2002.
83. i-coupled Src kinase signaling pathway. J Cell Biol 150: 1057-1070, 2000.
84. Mostov KE and Cardone MH. Regulation of protein traffic in polarized epithelial cells. Bioessays 17: 129-138, 1995.
85. Newman GR, Campbell L, von Ruhland C, Jasani B, and Gumbleton M. Caveolin and its cellular and subcellular immunolocalisation in lung alveolar epithelium: implications for alveolar epithelial type I cell function. Cell Tissue Res 295: 111-120, 1999.
86. Paciga JE, Shelley SA, and Balis JU. Secretory IgA is a component of rabbit lung surfactant. Biochim Biophys Acta 631: 487-494, 1980.
87. Pietra GG, Sampson P, Lanken PN, Hansen-Flaschen J, and Fishman AP. Transcapillary movement of cationized ferritin in the isolated perfused rat lung. Lab Invest 49: 54-61, 1983.
88. Pittet JF, Matthay MA, Pier G, Grady M, and Wiener-Kronish JP. Pseudomonas aeruginosa-induced lung and pleural injury in sheep. Differential protective effect of circulating vs. alveolar immunoglobulin G antibody. J Clin Invest 92: 1221-1228, 1993.
89. Pittet JF, Wiener-Kronish JP, McElroy MC, Folkesson HG, and Matthay MA. Stimulation of lung epithelial liquid clearance by endogenous release of catecholamines in septic shock in anesthetized rats. J Clin Invest 94: 663-671, 1994.
90. Pittet JF, Wiener-Kronish JP, Serikov V, and Matthay MA. Resistance of the alveolar epithelium to injury from septic shock in sheep. Am J Respir Crit Care Med 151: 1093-1100, 1995.
91. Razani B, Engelman JA, Wang XB, Schubert W, Zhang XL, Marks CB, Macaluso F, Russell RG, Li M, Pestell RG, Di Vizio D, Hou H Jr, Knietz B, Lagaud G, Christ GJ, Edelmann W, and Lisanti MP. Caveolin-1 null mice are viable, but show evidence of hyperproliferative and vascular abnormalities. J Biol Chem 16: 16, 2001.
92. Rishi AK, Joyce-Brady M, Fisher J, Dobbs LG, Floros J, VanderSpek J, Brody JS, and Williams MC. Cloning, characterization, and development expression of a rat lung alveolar type I cell gene in embryonic endodermal and neural derivatives. Dev Biol 167: 294-306, 1995.
93. Rossen RD, Morgan C, Hsu KC, Butler WT, and Rose HM. Localization of 11S external secretory IgA by immunofluorescence in tissues lining the oral and respiratory passages in man. J Immunol 100: 706-717, 1968.
94. Ryan RM, Morris RE, Rice WR, Ciraolo G, and Whitsett JA. Binding and uptake of pulmonary surfactant protein (SP-A) by pulmonary type II epithelial cells. J Histochem Cytochem 37: 429-440, 1989.
95. Saji F, Samejima Y, Kamiura S, and Koyama M. Dynamics of immunoglobulins at the feto-maternal interface. Rev Reprod 4: 81-89, 1999.
96. Sakuma T, Pittet JF, Jayr C, and Matthay MA. Alveolar liquid and protein clearance in the absence of blood flow or ventilation in sheep. J Appl Physiol 74: 176-185, 1993.
97. Schneeberger EE. The permeability of the alveolar-capillary membrane to ultrastructural protein tracers. Ann NY Acad Sci 221: 238-243, 1974.
98. Schneeberger EE. Ultrastructural basis for alveolar-capillary permeability to protein. Ciba Found Symp 38: 3-28, 1976.
99. Schneeberger EE. Structural basis for some permeability properties of the air-blood barrier. Fed Proc 37: 2471-2478, 1978.
100. Schnitzer JE. gp60 is an albumin-binding glycoprotein expressed by continuous endothelium involved in albumin transcytosis. Am J Physiol Heart Circ Physiol 262: H246-H254, 1992.
101. Schultz AL, Grisme JT, Wada S, and Grande F. Absorption of albumin from alveoli of perfused dog lung. Am J Physiol 207: 1300-1304, 1964.
102. Simister NE and Mostov KE. An Fc receptor structurally related to MHC class I antigens. Nature 337: 184-187, 1989.
103. Simister NE and Story CM. Human placental Fc receptors and the transmission of antibodies from mother to fetus. J Reprod Immunol 37: 1-23, 1997.
104. Simister NE, Story CM, Chen HL, and Hunt JS. An IgG-transporting Fc receptor expressed in the syncytiotrophoblast of human placenta. Eur J Immunol 26: 1527-1531, 1996.
105. Smedira N, Gates L, Hastings R, Jayr C, Sakuma T, Pittet JF, and Matthay MA. Alveolar and lung liquid clearance in anesthetized rabbits. J Appl Physiol 70: 1827-1835, 1991.
106. Sprung CL, Long WM, Marcial EH, Schein RM, Parker RE, Shomer T, and Brigham KL. Distribution of proteins in pulmonary edema. The value of fractional concentrations. Am Rev Respir Dis 136: 957-963, 1987.
107. Staub NC. New concepts about the pathophysiology of pulmonary edema. J Thorac Imaging 3: 8-14, 1988.
108. Staub NC, Gee M, and Vreim C. Mechanism of alveolar flooding in acute pulmonary oedema. Ciba Found Symp 38: 255-272, 1976.
109. Stefaner I, Praetor A, and Hunziker W. Nonvectorial surface transport, endocytosis via a Di-leucine-based motif, and bidirectional transcytosis of chimera encoding the cytosolic tail of rat FcRn expressed in Madin-Darby canine kidney cells. J Biol Chem 274: 8998-9005, 1999.
110. Stockley RA and Burnett D. Local IgA production in patients with chronic bronchitis: effect of acute respiratory infection. Thorax 35: 202-206, 1980.
111. Takemura T and Eishi Y. Distribution of secretory component and immunoglobulins in the developing lung. Am Rev Respir Dis 131: 125-130, 1985.
112. Taylor AE and Gaar KA. Estimation of equivalent pore radii of pulmonary capillary and alveolar membranes. Am J Physiol 218: 1133-1140, 1970.
113. Theodore J, Robin ED, Gaudio R, and Acevedo J. Transalveolar transport of large polar solutes (sucrose, inulin, and dextran). Am J Physiol 229: 989-996, 1975.
114. Tiruppathi C, Finnegan A, and Malik AB. Isolation and characterization of a cell surface albumin-binding protein from vascular endothelial cells. Proc Natl Acad Sci USA 93: 250-254, 1996.
115. Tiruppathi C, Song W, Bergenfeldt M, Sass P, and Malik AB. Gp60 activation mediates albumin transcytosis in endothelial cells by tyrosine kinase-dependent pathway. J Biol Chem 272: 25968-25975, 1997.
116. Tomashefski JF. Pulmonary pathology of the adult respiratory distress syndrome. Clin Chest Med 11: 593-619, 1990.
117. Verkman AS, Matthay MA, and Song Y. Aquaporin water channels and lung physiology. Am J Physiol Lung Cell Mol Physiol 278: L867-L879, 2000.
118. Vogel SM, Easington CR, Minshall RD, Niles WD, Tiruppathi C, Hollenberg SM, Parrillo JE, and Malik AB. Evidence of transcellular permeability pathway in microvessels. Microvasc Res 61: 87-101, 2001.
119. Vogel SM, Minshall RD, Pilipovic M, Tiruppathi C, and Malik AB. Albumin uptake and transcytosis in endothelial cells in vivo induced by albumin-binding protein. Am J Physiol Lung Cell Mol Physiol 281: L1512-L1522, 2001.
120. Wangensteen D and Yankovich R. Alveolar epithelium transport of albumin and sucrose: concentration difference effect. J Appl Physiol 47: 846-850, 1979.
121. Wiener-Kronish JP, Albertine KH, and Matthay MA. Differential responses of the endothelial and epithelial barriers of the lung in sheep to Escherichia coli endotoxin. J Clin Invest 88: 864-875, 1991.
122. Wiener-Kronish JP, Broaddus VC, Albertine KH, Gropper MA, Matthay MA, and Staub NC. Relationship of pleural effusions to increased permeability pulmonary edema in anesthetized sheep. J Clin Invest 82: 1422-1429, 1988.
123. Williams MC. Endocytosis in alveolar type II cells: effect of charge and size of tracers. Proc Natl Acad Sci USA 81: 6054-6058, 1984.
124. Williams MC. Uptake of lectins by pulmonary alveolar type II cells: subsequent deposition into lamellar bodies. Proc Natl Acad Sci USA 81: 6383-6387, 1984.
125. r = 26,000-36,000 enhances uptake of liposomes by type II cells. J Biol Chem 262: 2888-2894, 1987.
126. Zhou HY, Okamoto CT, Elbert KJ, Lee VHL, Crandall ED, and Kim KJ. Interferon gamma modulation of polymeric immunoglobulin receptor expression in alveolar epithelial cells (Abstract). FASEB J 11: A128, 1997.