In vitro evaluation of microparticles and polymer gels for use as nasal platforms for protein delivery

Pharmaceutical Research

Volumn 16, Issue 3, 1999, Pages 382-390

  Witschi, Claudia ^a,b   Mrsny, Randall J ^a  

^a GENENTECH INC   (United States)

^b FIBROGEN INC   (United States)

Author keywords

Bioadhesive polymers; Calu 3 cells; In vitro release; Microparticles; Nasal delivery

Indexed keywords

ALGINIC ACID; BOVINE SERUM ALBUMIN; CARBOMER; CHITOSAN; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LYSOPHOSPHATIDYLCHOLINE; NOSE SPRAY; POLYMER; STARCH; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BIOCOMPATIBILITY; CELL CULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG UPTAKE; GEL; IN VITRO STUDY; LASER DIFFRACTION; MEAN RESIDENCE TIME; NONHUMAN; NOSE MUCOSA; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN TRANSPORT; RESPIRATORY EPITHELIUM; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY;

EID: 0032961328     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018869601502     Document Type: Article

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