4-Hydroxynonenal triggers multistep signal transduction cascades for suppression of cellular functions

Molecular Aspects of Medicine

Volumn 24, Issue 4-5, 2003, Pages 231-238

  Nakashima, Izumi ^a   Liu, Wei ^a   Akhand, Anwarul A ^a   Takeda, Kozue ^a   Kawamoto, Yoshiyuki ^a   Kato, Masashi ^a   Suzuki, Haruhiko ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

4 Hydroxynonenal; Akt; Apoptosis; Caspase; Cell cycle arrest; Epithelial growth factor receptor; Glutathione; Lipid peroxidation; NF B; Nitric oxide; Oxidative stress; Protein phosphatase 2A; Reactive oxygen species; Redox; Signal transduction; Src kinase

Indexed keywords

4 HYDROXYNONENAL; ALDEHYDE; AMINO ACID; CASPASE; CELL MEMBRANE PROTEIN; CELL PROTEIN; CELL SURFACE PROTEIN; CELL SURFACE RECEPTOR; DNA FRAGMENT; EPIDERMAL GROWTH FACTOR RECEPTOR; FAS ANTIGEN; GLUTATHIONE; I KAPPA B; IMIDAZOLE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MEMBRANE LIPID; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE SYNTHASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE B; PROTEIN SHC; PROTEIN TYROSINE KINASE; SCAVENGER; THIOL DERIVATIVE;

APOPTOSIS; CELL DEATH; CELL FUNCTION; CELL GROWTH; CELL SURFACE; CONFERENCE PAPER; DEPHOSPHORYLATION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; FEEDBACK SYSTEM; GROWTH INHIBITION; HUMAN; LIGAND BINDING; LIPID PEROXIDATION; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN TARGETING; RECEPTOR BINDING; REGULATORY MECHANISM; SERUM; SIGNAL TRANSDUCTION;

EID: 0042671381     PISSN: 00982997     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0098-2997(03)00018-9     Document Type: Conference Paper

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