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Volumn 64, Issue 1, 2004, Pages 89-98

The role of metabotropic glutamate receptors in Alzheimer's disease

Author keywords

Alzheimer's disease; Glutamate receptor; Selective neurodegeneration

Indexed keywords

METABOTROPIC RECEPTOR;

EID: 1842607573     PISSN: 00651400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (49)

References (94)
  • 1
    • 0033011390 scopus 로고    scopus 로고
    • Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury
    • Allen JW, Ivanova SA, Fan L, Espey MG, Basile AS, Faden AI (1999) Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury. J Pharmacol Exp Ther 290: 112-120.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 112-120
    • Allen, J.W.1    Ivanova, S.A.2    Fan, L.3    Espey, M.G.4    Basile, A.S.5    Faden, A.I.6
  • 2
    • 0028350662 scopus 로고
    • AMPA-selective glutamate receptor subtype immunoreactivity in the entorhinal cortex of non-demented elderly and patients with Alzheimer's disease
    • Armstrong DM, Ikonomovic MD, Sheffield R, Wenthold RJ (1994) AMPA-selective glutamate receptor subtype immunoreactivity in the entorhinal cortex of non-demented elderly and patients with Alzheimer's disease. Brain Res 639: 207-216.
    • (1994) Brain Res , vol.639 , pp. 207-216
    • Armstrong, D.M.1    Ikonomovic, M.D.2    Sheffield, R.3    Wenthold, R.J.4
  • 3
    • 0342617716 scopus 로고    scopus 로고
    • Non-plaque dystrophic dendrites in Alzheimer hippocampus: A new pathological structure revealed by glutamate receptor immunocytochemistry
    • Aronica E, Dickson DW, Kress Y, Morrison JH, Zukin RS (1998) Non-plaque dystrophic dendrites in Alzheimer hippocampus: a new pathological structure revealed by glutamate receptor immunocytochemistry. Neuroscience 82: 979-991.
    • (1998) Neuroscience , vol.82 , pp. 979-991
    • Aronica, E.1    Dickson, D.W.2    Kress, Y.3    Morrison, J.H.4    Zukin, R.S.5
  • 4
    • 0035958752 scopus 로고    scopus 로고
    • Immunohistochemical localization of group I and II metabotropic glutamate receptors in control and amyotrophic lateral sclerosis human spinal cord: Upregulation in reactive astrocytes
    • Aronica E, Catania MV, Geurts J, Yankaya B, Troost D (2001) Immunohistochemical localization of group I and II metabotropic glutamate receptors in control and amyotrophic lateral sclerosis human spinal cord: upregulation in reactive astrocytes. Neuroscience 105: 509-520.
    • (2001) Neuroscience , vol.105 , pp. 509-520
    • Aronica, E.1    Catania, M.V.2    Geurts, J.3    Yankaya, B.4    Troost, D.5
  • 5
    • 0038810014 scopus 로고    scopus 로고
    • Expression and functional role of mGluR3 and mGluR5 in human astrocytes and glioma cells: Opposite regulation of glutamate transporter proteins
    • Aronica E, Gorter JA, Ijlst-Keizers H, Rozemuller AJ, Yankaya B, Leenstra S, Troost D (2003) Expression and functional role of mGluR3 and mGluR5 in human astrocytes and glioma cells: opposite regulation of glutamate transporter proteins. Eur J Neurosci 17: 2106-2118.
    • (2003) Eur J Neurosci , vol.17 , pp. 2106-2118
    • Aronica, E.1    Gorter, J.A.2    Ijlst-Keizers, H.3    Rozemuller, A.J.4    Yankaya, B.5    Leenstra, S.6    Troost, D.7
  • 6
    • 0035924328 scopus 로고    scopus 로고
    • Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia
    • Bao WL, Williams AJ, Faden AI, Tortella FC (2001) Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia. Brain Res 922: 173-179.
    • (2001) Brain Res , vol.922 , pp. 173-179
    • Bao, W.L.1    Williams, A.J.2    Faden, A.I.3    Tortella, F.C.4
  • 7
    • 0030852182 scopus 로고    scopus 로고
    • In vivo inhibition of veratridine-evoked release of striatal excitatory amino acids by the group II metabotropic glutamate receptor agonist LY354740 in rats
    • Battaglia G, Monn JA, Schoepp DD (1997) In vivo inhibition of veratridine-evoked release of striatal excitatory amino acids by the group II metabotropic glutamate receptor agonist LY354740 in rats. Neurosci Lett 229: 161-164.
    • (1997) Neurosci Lett , vol.229 , pp. 161-164
    • Battaglia, G.1    Monn, J.A.2    Schoepp, D.D.3
  • 8
    • 0034948146 scopus 로고    scopus 로고
    • Selective blockade of type-1 metabotropic glutamate receptors induces neuroprotection by enhancing gabaergic transmission
    • Battaglia G, Bruno V, Pisani A, Centonze D, Catania MV, Calabresi P, Nicoletti F (2001) Selective blockade of type-1 metabotropic glutamate receptors induces neuroprotection by enhancing gabaergic transmission. Mol Cell Neurosci 17: 1071-1083.
    • (2001) Mol Cell Neurosci , vol.17 , pp. 1071-1083
    • Battaglia, G.1    Bruno, V.2    Pisani, A.3    Centonze, D.4    Catania, M.V.5    Calabresi, P.6    Nicoletti, F.7
  • 9
    • 0037102726 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease
    • Bi H, Sze CI (2002) N-methyl-D-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease. J Neurol Sci 200: 11-18.
    • (2002) J Neurol Sci , vol.200 , pp. 11-18
    • Bi, H.1    Sze, C.I.2
  • 11
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82: 239-259.
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 12
    • 0029121515 scopus 로고
    • Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration
    • Bruno V, Battaglia G, Copani A, Giffard RG, Raciti G, Raffaele R, Shinozaki H, Nicoletti F (1995a) Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration. Eur J Neurosci 7: 1906-1913.
    • (1995) Eur J Neurosci , vol.7 , pp. 1906-1913
    • Bruno, V.1    Battaglia, G.2    Copani, A.3    Giffard, R.G.4    Raciti, G.5    Raffaele, R.6    Shinozaki, H.7    Nicoletti, F.8
  • 13
    • 0029131714 scopus 로고
    • Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells
    • Bruno V, Copani A, Knopfel T, Kuhn R, Casabona G, Dell'Albani P, Condorelli DF, Nicoletti F (1995b) Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells. Neuropharmacology 34: 1089-1098.
    • (1995) Neuropharmacology , vol.34 , pp. 1089-1098
    • Bruno, V.1    Copani, A.2    Knopfel, T.3    Kuhn, R.4    Casabona, G.5    Dell'Albani, P.6    Condorelli, D.F.7    Nicoletti, F.8
  • 14
    • 0032403407 scopus 로고    scopus 로고
    • Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-beta
    • Bruno V, Battaglia G, Casabona G, Copani A, Caciagli F, Nicoletti F (1998) Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-beta. J Neurosci 18: 9594-9600.
    • (1998) J Neurosci , vol.18 , pp. 9594-9600
    • Bruno, V.1    Battaglia, G.2    Casabona, G.3    Copani, A.4    Caciagli, F.5    Nicoletti, F.6
  • 15
    • 0033046392 scopus 로고    scopus 로고
    • Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): Comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 receptors
    • Bruno V, Battaglia G, Kingston A, O'Neill MJ, Catania MV, Di Grezia R, Nicoletti F (1999) Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 receptors. Neuropharmacology 38: 199-207.
    • (1999) Neuropharmacology , vol.38 , pp. 199-207
    • Bruno, V.1    Battaglia, G.2    Kingston, A.3    O'Neill, M.J.4    Catania, M.V.5    Di Grezia, R.6    Nicoletti, F.7
  • 18
    • 0029156276 scopus 로고
    • The inhibitory mGluR agonist, S-4-carboxy-3-hydroxy-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death
    • Buisson A, Choi DW (1995) The inhibitory mGluR agonist, S-4-carboxy-3-hydroxy-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death. Neuropharmacology 34: 1081-1087.
    • (1995) Neuropharmacology , vol.34 , pp. 1081-1087
    • Buisson, A.1    Choi, D.W.2
  • 19
    • 0030031001 scopus 로고    scopus 로고
    • DCG-IV selectively attenuates rapidly triggered NMDA-induced neurotoxicity in cortical neurons
    • Buisson A, Yu SP, Choi DW (1996) DCG-IV selectively attenuates rapidly triggered NMDA-induced neurotoxicity in cortical neurons. Eur J Neurosci 8: 138-143.
    • (1996) Eur J Neurosci , vol.8 , pp. 138-143
    • Buisson, A.1    Yu, S.P.2    Choi, D.W.3
  • 20
    • 0032818776 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors and cell-type-specific vulnerability in the striatum: Implication for ischemia and Huntington's disease
    • Calabresi P, Centonze D, Pisani A, Bernardi G (1999) Metabotropic glutamate receptors and cell-type-specific vulnerability in the striatum: implication for ischemia and Huntington's disease. Exp Neurol 158: 97-108.
    • (1999) Exp Neurol , vol.158 , pp. 97-108
    • Calabresi, P.1    Centonze, D.2    Pisani, A.3    Bernardi, G.4
  • 21
    • 0034068655 scopus 로고    scopus 로고
    • Attenuation of specific PCP-evoked behaviors by the potent mGlu2/3 receptor agonist, LY379268 and comparison with the atypical antipsychotic, clozapine
    • Cartmell J, Monn JA, Schoepp DD (2000) Attenuation of specific PCP-evoked behaviors by the potent mGlu2/3 receptor agonist, LY379268 and comparison with the atypical antipsychotic, clozapine. Psychopharmacology (Berl) 148: 423-429.
    • (2000) Psychopharmacology (Berl) , vol.148 , pp. 423-429
    • Cartmell, J.1    Monn, J.A.2    Schoepp, D.D.3
  • 22
    • 0034851667 scopus 로고    scopus 로고
    • NMDA receptors and learning and memory processes
    • Castellano C, Cestari V, Ciamei A (2001) NMDA receptors and learning and memory processes. Curr Drug Targets 2: 273-283.
    • (2001) Curr Drug Targets , vol.2 , pp. 273-283
    • Castellano, C.1    Cestari, V.2    Ciamei, A.3
  • 23
    • 0025138490 scopus 로고
    • Differential alterations of cortical glutamatergic binding sites in senile dementia of the Alzheimer type
    • Chalmers DT, Dewar D, Graham DI, Brooks DN, McCulloch J (1990) Differential alterations of cortical glutamatergic binding sites in senile dementia of the Alzheimer type. Proc Natl Acad Sci U S A 87: 1352-1356.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 1352-1356
    • Chalmers, D.T.1    Dewar, D.2    Graham, D.I.3    Brooks, D.N.4    McCulloch, J.5
  • 24
    • 0026647040 scopus 로고
    • Activation of metabotropic receptors has a neuroprotective effect in a rodent model of focal ischaemia
    • Chiamulera C, Albertini P, Valerio E, Reggiani A (1992) Activation of metabotropic receptors has a neuroprotective effect in a rodent model of focal ischaemia. Eur J Pharmacol 216: 335-336.
    • (1992) Eur J Pharmacol , vol.216 , pp. 335-336
    • Chiamulera, C.1    Albertini, P.2    Valerio, E.3    Reggiani, A.4
  • 25
    • 0025265926 scopus 로고
    • The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death
    • Choi DW, Rothman SM (1990) The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu Rev Neurosci 13: 171-182.
    • (1990) Annu Rev Neurosci , vol.13 , pp. 171-182
    • Choi, D.W.1    Rothman, S.M.2
  • 26
    • 0034078492 scopus 로고    scopus 로고
    • Group I mGluR activation turns on a voltage-gated inward current in hippocampal pyramidal cells
    • Chuang SC, Bianchi R, Wong RK (2000) Group I mGluR activation turns on a voltage-gated inward current in hippocampal pyramidal cells. J Neurophysiol 83: 2844-2853.
    • (2000) J Neurophysiol , vol.83 , pp. 2844-2853
    • Chuang, S.C.1    Bianchi, R.2    Wong, R.K.3
  • 27
    • 0036583275 scopus 로고    scopus 로고
    • A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat
    • Clayton DA, Mesches MH, Alvarez E, Bickford PC, Browning MD (2002) A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat. J Neurosci 22: 3628-3637.
    • (2002) J Neurosci , vol.22 , pp. 3628-3637
    • Clayton, D.A.1    Mesches, M.H.2    Alvarez, E.3    Bickford, P.C.4    Browning, M.D.5
  • 28
    • 0029016730 scopus 로고
    • Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide
    • Copani A, Bruno V, Battaglia G, Leanza G, Pellitteri R, Russo A, Stanzani S, Nicoletti F (1995) Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide. Mol Pharmacol 47: 890-897.
    • (1995) Mol Pharmacol , vol.47 , pp. 890-897
    • Copani, A.1    Bruno, V.2    Battaglia, G.3    Leanza, G.4    Pellitteri, R.5    Russo, A.6    Stanzani, S.7    Nicoletti, F.8
  • 30
    • 85026134102 scopus 로고    scopus 로고
    • Up-regulation of soluble amyloid precursor protein fragment secretion in the rat retina in vivo by metabotropic glutamate receptor stimulation
    • Croucher MJ, Patel H, Walsh DT, Moncaster JA, Gentleman SM, Fazal A, Jen LS (2003) Up-regulation of soluble amyloid precursor protein fragment secretion in the rat retina in vivo by metabotropic glutamate receptor stimulation. Neuroreport 14: 2271-2274.
    • (2003) Neuroreport , vol.14 , pp. 2271-2274
    • Croucher, M.J.1    Patel, H.2    Walsh, D.T.3    Moncaster, J.A.4    Gentleman, S.M.5    Fazal, A.6    Jen, L.S.7
  • 31
    • 0025785213 scopus 로고
    • Glutamate metabotropic and AMPA binding sites are reduced in Alzheimer's disease: An autoradiographic study of the hippocampus
    • Dewar D, Chalmers DT, Graham DI, McCulloch J (1991) Glutamate metabotropic and AMPA binding sites are reduced in Alzheimer's disease: an autoradiographic study of the hippocampus. Brain Res 553: 58-64.
    • (1991) Brain Res , vol.553 , pp. 58-64
    • Dewar, D.1    Chalmers, D.T.2    Graham, D.I.3    McCulloch, J.4
  • 32
    • 0030769436 scopus 로고    scopus 로고
    • Glutamate toxicity enhances tau gene expression in neuronal cultures
    • Esclaire F, Lesort M, Blanchard C, Hugon J (1997) Glutamate toxicity enhances tau gene expression in neuronal cultures. J Neurosci Res 49: 309-318.
    • (1997) J Neurosci Res , vol.49 , pp. 309-318
    • Esclaire, F.1    Lesort, M.2    Blanchard, C.3    Hugon, J.4
  • 33
    • 0031407416 scopus 로고    scopus 로고
    • Neuroprotective effects of group III mGluR in traumatic neuronal injury
    • Faden AI, Ivanova SA, Yakovlev AG, Mukhin AG (1997) Neuroprotective effects of group III mGluR in traumatic neuronal injury. J Neurotrauma 14: 885-895.
    • (1997) J Neurotrauma , vol.14 , pp. 885-895
    • Faden, A.I.1    Ivanova, S.A.2    Yakovlev, A.G.3    Mukhin, A.G.4
  • 34
    • 0033004346 scopus 로고    scopus 로고
    • Activation of the extracellular signal-regulated kinase 2 by metabotropic glutamate receptors
    • Ferraguti F, Baldani-Guerra B, Corsi M, Nakanishi S, Corti C (1999) Activation of the extracellular signal-regulated kinase 2 by metabotropic glutamate receptors. Eur J Neurosci 11: 2073-2082.
    • (1999) Eur J Neurosci , vol.11 , pp. 2073-2082
    • Ferraguti, F.1    Baldani-Guerra, B.2    Corsi, M.3    Nakanishi, S.4    Corti, C.5
  • 35
    • 0027269660 scopus 로고
    • Cortical pyramidal neurone loss may cause glutamatergic hypoactivity and cognitive impairment in Alzheimer's disease: Investigative and therapeutic perspectives
    • Francis PT, Sims NR, Procter AW, Bowen DM (1993) Cortical pyramidal neurone loss may cause glutamatergic hypoactivity and cognitive impairment in Alzheimer's disease: investigative and therapeutic perspectives. J Neurochem 60: 1589-1604.
    • (1993) J Neurochem , vol.60 , pp. 1589-1604
    • Francis, P.T.1    Sims, N.R.2    Procter, A.W.3    Bowen, D.M.4
  • 36
    • 0029841562 scopus 로고    scopus 로고
    • Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain
    • Furukawa K, Sopher BL, Rydel RE, Begley JG, Pham DG, Martin GM, Fox M, Mattson MP (1996) Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain. J Neurochem 67: 1882-1896.
    • (1996) J Neurochem , vol.67 , pp. 1882-1896
    • Furukawa, K.1    Sopher, B.L.2    Rydel, R.E.3    Begley, J.G.4    Pham, D.G.5    Martin, G.M.6    Fox, M.7    Mattson, M.P.8
  • 38
    • 0022546807 scopus 로고
    • Plasticity in hippocampal excitatory amino acid receptors in Alzheimer's disease
    • Geddes JW, Cotman CW (1986) Plasticity in hippocampal excitatory amino acid receptors in Alzheimer's disease. Neurosci Res 3: 672-678.
    • (1986) Neurosci Res , vol.3 , pp. 672-678
    • Geddes, J.W.1    Cotman, C.W.2
  • 39
    • 0042266373 scopus 로고    scopus 로고
    • Altered expression patterns of group I and II metabotropic glutamate receptors in multiple sclerosis
    • Geurts JJ, Wolswijk G, Bo L, van der Valk P, Polman CH, Troost D, Aronica E (2003) Altered expression patterns of group I and II metabotropic glutamate receptors in multiple sclerosis. Brain 126: 1755-1766.
    • (2003) Brain , vol.126 , pp. 1755-1766
    • Geurts, J.J.1    Wolswijk, G.2    Bo, L.3    Van Der Valk, P.4    Polman, C.H.5    Troost, D.6    Aronica, E.7
  • 40
    • 0023270663 scopus 로고
    • Alzheimer's disease: Glutamate depletion in the hippocampal perforant pathway zone
    • Hyman BT, Van Hoesen GW, Damasio AR (1987) Alzheimer's disease: glutamate depletion in the hippocampal perforant pathway zone. Ann Neurol 22: 37-40.
    • (1987) Ann Neurol , vol.22 , pp. 37-40
    • Hyman, B.T.1    Van Hoesen, G.W.2    Damasio, A.R.3
  • 41
    • 0034938257 scopus 로고    scopus 로고
    • Glutamate(NMDA) receptor NR1 subunit mRNA expression in Alzheimer's disease
    • Hynd MR, Scott HL, Dodd PR (2001) Glutamate(NMDA) receptor NR1 subunit mRNA expression in Alzheimer's disease. J Neurochem 78: 175-182.
    • (2001) J Neurochem , vol.78 , pp. 175-182
    • Hynd, M.R.1    Scott, H.L.2    Dodd, P.R.3
  • 43
    • 0029554331 scopus 로고
    • AMPA-selective glutamate receptor subtype immunoreactivity in the hippocampal formation of patients with Alzheimer's disease
    • Ikonomovic MD, Sheffield R, Armstrong DM (1995) AMPA-selective glutamate receptor subtype immunoreactivity in the hippocampal formation of patients with Alzheimer's disease. Hippocampus 5: 469-486.
    • (1995) Hippocampus , vol.5 , pp. 469-486
    • Ikonomovic, M.D.1    Sheffield, R.2    Armstrong, D.M.3
  • 44
    • 0030930206 scopus 로고    scopus 로고
    • The loss of GluR2(3) immunoreactivity precedes neurofibrillary tangle formation in the entorhinal cortex and hippocampus of Alzheimer brains
    • Ikonomovic MD, Mizukami K, Davies P, Hamilton R, Sheffield R, Armstrong DM (1997) The loss of GluR2(3) immunoreactivity precedes neurofibrillary tangle formation in the entorhinal cortex and hippocampus of Alzheimer brains. J Neuropathol Exp Neurol 56: 1018-1027.
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 1018-1027
    • Ikonomovic, M.D.1    Mizukami, K.2    Davies, P.3    Hamilton, R.4    Sheffield, R.5    Armstrong, D.M.6
  • 45
    • 0032710970 scopus 로고    scopus 로고
    • Distribution of glutamate receptor subunit NMDAR1 in the hippocampus of normal elderly and patients with Alzheimer's disease
    • Ikonomovic MD, Mizukami K, Warde D, Sheffield R, Hamilton R, Wenthold RJ, Armstrong DM (1999) Distribution of glutamate receptor subunit NMDAR1 in the hippocampus of normal elderly and patients with Alzheimer's disease. Exp Neurol 160: 194-204.
    • (1999) Exp Neurol , vol.160 , pp. 194-204
    • Ikonomovic, M.D.1    Mizukami, K.2    Warde, D.3    Sheffield, R.4    Hamilton, R.5    Wenthold, R.J.6    Armstrong, D.M.7
  • 46
    • 0030208011 scopus 로고    scopus 로고
    • Beyond the neuronal circuitry
    • Kettenmann H (1996) Beyond the neuronal circuitry. Trends Neurosci 19: 305-306.
    • (1996) Trends Neurosci , vol.19 , pp. 305-306
    • Kettenmann, H.1
  • 47
    • 0031757268 scopus 로고    scopus 로고
    • Presynaptic inhibitory action of the group II metabotropic glutamate receptor agonists, LY354740 and DCG-IV
    • Kilbride J, Huang LQ, Rowan MJ, Anwyl R (1998) Presynaptic inhibitory action of the group II metabotropic glutamate receptor agonists, LY354740 and DCG-IV. Eur J Pharmacol 356: 149-157.
    • (1998) Eur J Pharmacol , vol.356 , pp. 149-157
    • Kilbride, J.1    Huang, L.Q.2    Rowan, M.J.3    Anwyl, R.4
  • 48
    • 0032791811 scopus 로고    scopus 로고
    • Neuroprotection by metabotropic glutamate receptor glutamate receptor agonists: LY354740, LY379268 and LY389795
    • Kingston AE, O'Neill MJ, Lam A, Bales KR, Monn JA, Schoepp DD (1999) Neuroprotection by metabotropic glutamate receptor glutamate receptor agonists: LY354740, LY379268 and LY389795. Eur J Pharmacol 377:155-165.
    • (1999) Eur J Pharmacol , vol.377 , pp. 155-165
    • Kingston, A.E.1    O'Neill, M.J.2    Lam, A.3    Bales, K.R.4    Monn, J.A.5    Schoepp, D.D.6
  • 49
    • 0033977117 scopus 로고    scopus 로고
    • L-glutamate, L-arginine and L-citrulline levels in cerebrospinal fluid of Parkinson's disease, multiple system atrophy, and Alzheimer's disease patients
    • Kuiper MA, Teerlink T, Visser JJ, Bergmans PL, Scheltens P, Wolters EC (2000) L-glutamate, L-arginine and L-citrulline levels in cerebrospinal fluid of Parkinson's disease, multiple system atrophy, and Alzheimer's disease patients. J Neural Transm 107: 183-189.
    • (2000) J Neural Transm , vol.107 , pp. 183-189
    • Kuiper, M.A.1    Teerlink, T.2    Visser, J.J.3    Bergmans, P.L.4    Scheltens, P.5    Wolters, E.C.6
  • 50
    • 0035800188 scopus 로고    scopus 로고
    • Differential expression of Group I metabotropic glutamate receptors in motoneurons at low and high risk for degeneration in ALS
    • Laslo P, Lipski J, Funk GD (2001) Differential expression of Group I metabotropic glutamate receptors in motoneurons at low and high risk for degeneration in ALS. Neuroreport 12: 1903-1908.
    • (2001) Neuroreport , vol.12 , pp. 1903-1908
    • Laslo, P.1    Lipski, J.2    Funk, G.D.3
  • 53
    • 0029935359 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors regulate APP processing in hippocampal neurons and cortical astrocytes derived from fetal rats
    • Lee RK, Jimenez J, Cox AJ, Wurtman RJ (1996) Metabotropic glutamate receptors regulate APP processing in hippocampal neurons and cortical astrocytes derived from fetal rats. Ann N Y Acad Sci 777: 338-343.
    • (1996) Ann N Y Acad Sci , vol.777 , pp. 338-343
    • Lee, R.K.1    Jimenez, J.2    Cox, A.J.3    Wurtman, R.J.4
  • 54
    • 0036179194 scopus 로고    scopus 로고
    • Excitotoxicity: Perspectives based on N-methyl-D-aspartate receptor subtypes
    • Lynch DR, Guttmann RP (2002) Excitotoxicity: perspectives based on N-methyl-D-aspartate receptor subtypes. J Pharmacol Exp Ther 300: 717-723.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 717-723
    • Lynch, D.R.1    Guttmann, R.P.2
  • 55
    • 0035145543 scopus 로고    scopus 로고
    • Group II metabotropic glutamate receptor activation protects striatal dopaminergic nerve terminals against MPP(+)-induced neurotoxicity along with brain-derived neurotrophic factor induction
    • Matarredona ER, Santiago M, Venero JL, Cano J, Machado A (2001) Group II metabotropic glutamate receptor activation protects striatal dopaminergic nerve terminals against MPP(+)-induced neurotoxicity along with brain-derived neurotrophic factor induction. J Neurochem 76: 351-360.
    • (2001) J Neurochem , vol.76 , pp. 351-360
    • Matarredona, E.R.1    Santiago, M.2    Venero, J.L.3    Cano, J.4    Machado, A.5
  • 56
    • 0023125256 scopus 로고
    • The physiology of excitatory amino acids in the vertebrate central nervous system
    • Mayer ML, Westbrook GL (1987) The physiology of excitatory amino acids in the vertebrate central nervous system. Prog Neurobiol 28: 197-276.
    • (1987) Prog Neurobiol , vol.28 , pp. 197-276
    • Mayer, M.L.1    Westbrook, G.L.2
  • 57
    • 0033537306 scopus 로고    scopus 로고
    • Signal transduction abnormalities in Alzheimer's disease: Evidence of a pathogenic stimuli
    • McShea A, Zelasko DA, Gerst JL, Smith MA (1999) Signal transduction abnormalities in Alzheimer's disease: evidence of a pathogenic stimuli. Brain Res 815: 237-242.
    • (1999) Brain Res , vol.815 , pp. 237-242
    • McShea, A.1    Zelasko, D.A.2    Gerst, J.L.3    Smith, M.A.4
  • 58
    • 0025063609 scopus 로고
    • Excitatory amino acid neurotoxicity and neurodegenerative disease
    • Meldrum B, Garthwaite J (1990) Excitatory amino acid neurotoxicity and neurodegenerative disease. Trends Pharmacol Sci 11: 379-387.
    • (1990) Trends Pharmacol Sci , vol.11 , pp. 379-387
    • Meldrum, B.1    Garthwaite, J.2
  • 59
    • 0029027073 scopus 로고
    • Growth factor upregulation of a phosphoinositide-coupled metabotropic glutamate receptor in cortical astrocytes
    • Miller S, Romano C, Cotman CW (1995) Growth factor upregulation of a phosphoinositide-coupled metabotropic glutamate receptor in cortical astrocytes. J Neurosci 15: 6103-6109.
    • (1995) J Neurosci , vol.15 , pp. 6103-6109
    • Miller, S.1    Romano, C.2    Cotman, C.W.3
  • 60
    • 0031028197 scopus 로고    scopus 로고
    • Anticonvulsive and neuroprotective actions of a potent agonist (DCG-IV) for group II metabotropic glutamate receptors against intraventricular kainate in the rat
    • Miyamoto M, Ishida M, Shinozaki H (1997) Anticonvulsive and neuroprotective actions of a potent agonist (DCG-IV) for group II metabotropic glutamate receptors against intraventricular kainate in the rat. Neuroscience 77: 131-140.
    • (1997) Neuroscience , vol.77 , pp. 131-140
    • Miyamoto, M.1    Ishida, M.2    Shinozaki, H.3
  • 61
    • 0024596865 scopus 로고
    • The excitatory amino acid receptors: Their classes, pharmacology, and distinct properties in the function of the central nervous system
    • Monaghan DT, Bridges RJ, Cotman CW (1989) The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system. Annu Rev Pharmacol Toxicol 29: 365-402.
    • (1989) Annu Rev Pharmacol Toxicol , vol.29 , pp. 365-402
    • Monaghan, D.T.1    Bridges, R.J.2    Cotman, C.W.3
  • 63
    • 0033019102 scopus 로고    scopus 로고
    • The up-regulation of metabotropic glutamate receptor 5 (mGluR5) in Down's syndrome brains
    • Oka A, Takashima S (1999) The up-regulation of metabotropic glutamate receptor 5 (mGluR5) in Down's syndrome brains. Acta Neuropathol (Berl) 97:275-278.
    • (1999) Acta Neuropathol (Berl) , vol.97 , pp. 275-278
    • Oka, A.1    Takashima, S.2
  • 64
    • 84886422548 scopus 로고    scopus 로고
    • Pharmacology and neuroprotective actions of mGlu receptor ligands
    • O'Neill MJ (2001) Pharmacology and neuroprotective actions of mGlu receptor ligands. Dev Med Child Neurol Suppl 86: 13-15.
    • (2001) Dev Med Child Neurol Suppl , vol.86 , pp. 13-15
    • O'Neill, M.J.1
  • 65
    • 0033571938 scopus 로고    scopus 로고
    • Dopamine receptors and groups I and II mGluRs cooperate for long-term depression induction in rat prefrontal cortex through converging postsynaptic activation of MAP kinases
    • Otani S, Auclair N, Desce JM, Roisin MP, Crepel F (1999) Dopamine receptors and groups I and II mGluRs cooperate for long-term depression induction in rat prefrontal cortex through converging postsynaptic activation of MAP kinases. J Neurosci 19: 9788-9802.
    • (1999) J Neurosci , vol.19 , pp. 9788-9802
    • Otani, S.1    Auclair, N.2    Desce, J.M.3    Roisin, M.P.4    Crepel, F.5
  • 66
    • 0025822891 scopus 로고
    • Dissociable effects on spatial maze and passive avoidance acquisition and retention following AMPA- and ibotenic acid-induced excitotoxic lesions of the basal forebrain in rats: Differential dependence on cholinergic neuronal loss
    • Page KJ, Everitt BJ, Robbins TW, Marston HM, Wilkinson LS (1991) Dissociable effects on spatial maze and passive avoidance acquisition and retention following AMPA- and ibotenic acid-induced excitotoxic lesions of the basal forebrain in rats: differential dependence on cholinergic neuronal loss. Neuroscience 43: 457-472.
    • (1991) Neuroscience , vol.43 , pp. 457-472
    • Page, K.J.1    Everitt, B.J.2    Robbins, T.W.3    Marston, H.M.4    Wilkinson, L.S.5
  • 67
    • 0036166948 scopus 로고    scopus 로고
    • The mRNA of the NR1 subtype of glutamate receptor in Alzheimer's disease
    • Panegyres PK, Zafiris-Toufexis K, Kakulas BA (2002) The mRNA of the NR1 subtype of glutamate receptor in Alzheimer's disease. J Neural Transm 109: 77-89.
    • (2002) J Neural Transm , vol.109 , pp. 77-89
    • Panegyres, P.K.1    Zafiris-Toufexis, K.2    Kakulas, B.A.3
  • 68
    • 0021285256 scopus 로고
    • [3H]Kainic acid binding and choline acetyltransferase activity in Alzheimer's dementia
    • Pearce BR, Bowen DM (1984) [3H]Kainic acid binding and choline acetyltransferase activity in Alzheimer's dementia. Brain Res 310: 376-378.
    • (1984) Brain Res , vol.310 , pp. 376-378
    • Pearce, B.R.1    Bowen, D.M.2
  • 69
    • 0027196148 scopus 로고
    • Glutamate induces the growth factors NGF, bFGF, the receptor FGF-R1 and c-fos mRNA expression in rat astrocyte culture
    • Pechan PA, Chowdhury K, Gerdes W, Seifert W (1993) Glutamate induces the growth factors NGF, bFGF, the receptor FGF-R1 and c-fos mRNA expression in rat astrocyte culture. Neurosci Lett 153: 111-114.
    • (1993) Neurosci Lett , vol.153 , pp. 111-114
    • Pechan, P.A.1    Chowdhury, K.2    Gerdes, W.3    Seifert, W.4
  • 71
    • 0032514188 scopus 로고    scopus 로고
    • Human metabotropic glutamate receptor 2 couples to the MAP kinase cascade in chinese hamster ovary cells
    • Phillips T, Barnes A, Scott S, Emson P, Rees S (1998) Human metabotropic glutamate receptor 2 couples to the MAP kinase cascade in chinese hamster ovary cells. Neuroreport 9: 2335-2339.
    • (1998) Neuroreport , vol.9 , pp. 2335-2339
    • Phillips, T.1    Barnes, A.2    Scott, S.3    Emson, P.4    Rees, S.5
  • 72
    • 0029187946 scopus 로고
    • The metabotropic glutamate receptors: Structure and functions
    • Pin JP, Duvoisin R (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34: 1-26.
    • (1995) Neuropharmacology , vol.34 , pp. 1-26
    • Pin, J.P.1    Duvoisin, R.2
  • 73
    • 0033057319 scopus 로고    scopus 로고
    • New perspectives for the development of selective metabotropic glutamate receptor ligands
    • Pin JP, De Colle C, Bessis AS, Acher F (1999) New perspectives for the development of selective metabotropic glutamate receptor ligands. Eur J Pharmacol 375: 277-294.
    • (1999) Eur J Pharmacol , vol.375 , pp. 277-294
    • Pin, J.P.1    De Colle, C.2    Bessis, A.S.3    Acher, F.4
  • 74
    • 0029942307 scopus 로고    scopus 로고
    • Activation of multiple metabotropic glutamate receptor subtypes prevents NMDA-induced excitotoxicity in rat hippocampal slices
    • Pizzi M, Consolandi O, Memo M, Spano PF (1996) Activation of multiple metabotropic glutamate receptor subtypes prevents NMDA-induced excitotoxicity in rat hippocampal slices. Eur J Neurosci 8: 1516-1521.
    • (1996) Eur J Neurosci , vol.8 , pp. 1516-1521
    • Pizzi, M.1    Consolandi, O.2    Memo, M.3    Spano, P.F.4
  • 75
    • 0032969124 scopus 로고    scopus 로고
    • Reversal of glutamate excitotoxicity by activation of PKC-associated metabotropic glutamate receptors in cerebellar granule cells relies on NR2C subunit expression
    • Pizzi M, Boroni F, Bianchetti KM, Memo M, Spano P (1999) Reversal of glutamate excitotoxicity by activation of PKC-associated metabotropic glutamate receptors in cerebellar granule cells relies on NR2C subunit expression. Eur J Neurosci 11: 2489-2496.
    • (1999) Eur J Neurosci , vol.11 , pp. 2489-2496
    • Pizzi, M.1    Boroni, F.2    Bianchetti, K.M.3    Memo, M.4    Spano, P.5
  • 76
    • 0037980148 scopus 로고    scopus 로고
    • Alzheimer's β-amyloid peptide as a source of neurotoxic free radicals: The role of structural effects
    • Pogocki D (2003) Alzheimer's β-amyloid peptide as a source of neurotoxic free radicals: the role of structural effects. Acta Neurobiol Exp (Wars) 63: 131-145.
    • (2003) Acta Neurobiol Exp (Wars) , vol.63 , pp. 131-145
    • Pogocki, D.1
  • 78
    • 0032834028 scopus 로고    scopus 로고
    • Pharmacological agents acting at subtypes of metabotropic glutamate receptors
    • Schoepp DD, Jane DE, Monn JA (1999) Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacology 38: 1431-1476.
    • (1999) Neuropharmacology , vol.38 , pp. 1431-1476
    • Schoepp, D.D.1    Jane, D.E.2    Monn, J.A.3
  • 80
    • 0031614624 scopus 로고    scopus 로고
    • Alzheimer disease
    • Smith MA (1998) Alzheimer disease. Int Rev Neurobiol 42: 1-54.
    • (1998) Int Rev Neurobiol , vol.42 , pp. 1-54
    • Smith, M.A.1
  • 82
    • 0032101953 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor activation in vivo induces intraneuronal amyloid immunoreactivity in guinea pig hippocampus
    • Stephenson DT, Clemens JA (1998) Metabotropic glutamate receptor activation in vivo induces intraneuronal amyloid immunoreactivity in guinea pig hippocampus. Neurochem Int 33: 83-93.
    • (1998) Neurochem Int , vol.33 , pp. 83-93
    • Stephenson, D.T.1    Clemens, J.A.2
  • 83
    • 0035188745 scopus 로고    scopus 로고
    • N-Methyl-D-aspartate receptor subunit proteins and their phosphorylation status are altered selectively in Alzheimer's disease
    • Sze C, Bi H, Kleinschmidt-DeMasters BK, Filley CM, Martin LJ (2001) N-Methyl-D-aspartate receptor subunit proteins and their phosphorylation status are altered selectively in Alzheimer's disease. J Neurol Sci 182: 151-159.
    • (2001) J Neurol Sci , vol.182 , pp. 151-159
    • Sze, C.1    Bi, H.2    Kleinschmidt-DeMasters, B.K.3    Filley, C.M.4    Martin, L.J.5
  • 84
    • 0030777850 scopus 로고    scopus 로고
    • Alterations in glutamate receptor 2/3 subunits and amyloid precursor protein expression during the course of Alzheimer's disease and Lewy body variant
    • Thorns V, Mallory M, Hansen L, Masliah E (1997) Alterations in glutamate receptor 2/3 subunits and amyloid precursor protein expression during the course of Alzheimer's disease and Lewy body variant. Acta Neuropathol (Berl) 94: 539-548.
    • (1997) Acta Neuropathol (Berl) , vol.94 , pp. 539-548
    • Thorns, V.1    Mallory, M.2    Hansen, L.3    Masliah, E.4
  • 85
    • 0035881425 scopus 로고    scopus 로고
    • Expression of metabotropic glutamate receptor mRNAs in the human spinal cord: Implications for selective vulnerability of spinal motor neurons in amyotrophic lateral sclerosis
    • Tomiyama M, Kimura T, Maeda T, Tanaka H, Furusawa K, Kurahashi K, Matsunaga M (2001) Expression of metabotropic glutamate receptor mRNAs in the human spinal cord: implications for selective vulnerability of spinal motor neurons in amyotrophic lateral sclerosis. J Neurol Sci 189: 65-69.
    • (2001) J Neurol Sci , vol.189 , pp. 65-69
    • Tomiyama, M.1    Kimura, T.2    Maeda, T.3    Tanaka, H.4    Furusawa, K.5    Kurahashi, K.6    Matsunaga, M.7
  • 86
    • 0030785768 scopus 로고    scopus 로고
    • Decreased expression of N-methyl-D-aspartate receptor 1 messenger RNA in select regions of Alzheimer brain
    • Ulas J, Cotman CW (1997) Decreased expression of N-methyl-D-aspartate receptor 1 messenger RNA in select regions of Alzheimer brain. Neuroscience 79: 973-982.
    • (1997) Neuroscience , vol.79 , pp. 973-982
    • Ulas, J.1    Cotman, C.W.2
  • 88
    • 0028233830 scopus 로고
    • Basal forebrain cholinergic neurons are selectively vulnerable to AMPA/kainate receptor-mediated neurotoxicity
    • Weiss JH, Yin HZ, Choi DW (1994) Basal forebrain cholinergic neurons are selectively vulnerable to AMPA/kainate receptor-mediated neurotoxicity. Neuroscience 60: 659-664.
    • (1994) Neuroscience , vol.60 , pp. 659-664
    • Weiss, J.H.1    Yin, H.Z.2    Choi, D.W.3
  • 89
    • 0028952094 scopus 로고
    • Reduction of AMPA-selective glutamate receptor subunits in the entorhinal cortex of patients with Alzheimer's disease pathology: A biochemical study
    • Yasuda RP, Ikonomovic MD, Sheffield R, Rubin RT, Wolfe BB, Armstrong DM (1995) Reduction of AMPA-selective glutamate receptor subunits in the entorhinal cortex of patients with Alzheimer's disease pathology: a biochemical study. Brain Res 678: 161-167.
    • (1995) Brain Res , vol.678 , pp. 161-167
    • Yasuda, R.P.1    Ikonomovic, M.D.2    Sheffield, R.3    Rubin, R.T.4    Wolfe, B.B.5    Armstrong, D.M.6
  • 90
    • 0033083661 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor agonists reduce glutamate release from cultured astrocytes
    • Ye ZC, Sontheimer H (1999) Metabotropic glutamate receptor agonists reduce glutamate release from cultured astrocytes. Glia 25: 270-281.
    • (1999) Glia , vol.25 , pp. 270-281
    • Ye, Z.C.1    Sontheimer, H.2
  • 91
    • 0033782845 scopus 로고    scopus 로고
    • Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease
    • Zhu X, Rottkamp CA, Boux H, Takeda A, Perry G, Smith MA (2000) Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease. J Neuropathol Exp Neurol 59: 880-888.
    • (2000) J Neuropathol Exp Neurol , vol.59 , pp. 880-888
    • Zhu, X.1    Rottkamp, C.A.2    Boux, H.3    Takeda, A.4    Perry, G.5    Smith, M.A.6
  • 92
  • 93
    • 0035142804 scopus 로고    scopus 로고
    • Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease
    • Zhu X, Raina AK, Rottkamp CA, Aliev G, Perry G, Boux H, Smith MA (2001b) Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. J Neurochem 76: 435-441.
    • (2001) J Neurochem , vol.76 , pp. 435-441
    • Zhu, X.1    Raina, A.K.2    Rottkamp, C.A.3    Aliev, G.4    Perry, G.5    Boux, H.6    Smith, M.A.7


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