Studies on the active site of deacetoxycephalosporin C synthase

Journal of Molecular Biology

Volumn 287, Issue 5, 1999, Pages 943-960

  Lloyd, Matthew D ^a   Lee, Hwei Jen ^a   Harlos, Karl ^a   Zhang, Zhi Hong ^a   Baldwin, Jack E ^a   Schofield, Christopher J ^a   Charnock, John M ^b   Garner, C David ^b   Hara, Takane ^c   Terwisscha Van Scheltinga, Anke C ^d   Valegård, Karin ^c   Viklund, Jenny A C ^c   Hajdu, Janos ^c   Andersson, Inger ^d   Danielsson, Åke ^e   Bhikhabhai, Rama ^e  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UPPSALA UNIVERSITY   (Sweden)

^d SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^e GE Healthcare Bio Sciences AB   (Sweden)

Author keywords

2 Oxoglutarate; Antibiotic biosynthesis; Dioxygenase; EXAFS; Iron

Indexed keywords

DEACETOXYCEPHALOSPORIN C; PENICILLIN DERIVATIVE; SYNTHETASE;

ABSORPTION SPECTROSCOPY; ANTIBIOTIC BIOSYNTHESIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG TRANSFORMATION; ENZYME ACTIVE SITE; ENZYME PURIFICATION; ENZYME STABILITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; FOURIER TRANSFORMATION; GEL FILTRATION; HYDROGEN BOND; LIGHT SCATTERING; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REACTION ANALYSIS; STREPTOMYCES CLAVULIGERUS; X RAY CRYSTALLOGRAPHY;

EID: 0033574483     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.2594     Document Type: Article

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