-
1
-
-
0032039678
-
Cytochrome P450 monoxygenases
-
Wong L.L. Cytochrome P450 monoxygenases. Curr Opin Chem Biol. 2:1998;263-268.
-
(1998)
Curr Opin Chem Biol
, vol.2
, pp. 263-268
-
-
Wong, L.L.1
-
2
-
-
0344334423
-
Cytochrome P450: Structure, Mechanisms and Biochemistry
-
London: Plenum Press
-
Ortz de Montellano P.R. Cytochrome P450: Structure, Mechanisms and Biochemistry. edn 2:1995;Plenum Press, London.
-
(1995)
Edn 2
-
-
Ortz De Montellano, P.R.1
-
3
-
-
0032039677
-
Oxygen activating nonheme iron enzymes
-
Lange S.J., Que L. Oxygen activating nonheme iron enzymes. Curr Opin Chem Biol. 2:1998;159-172.
-
(1998)
Curr Opin Chem Biol
, vol.2
, pp. 159-172
-
-
Lange, S.J.1
Que, L.2
-
4
-
-
0031574232
-
The 2-His-1-carboxylate facial triad - an emerging structural motif in mononuclear non-heme iron(II) enzymes
-
Hegg E.L., Que L. The 2-His-1-carboxylate facial triad - an emerging structural motif in mononuclear non-heme iron(II) enzymes. Eur J Biochem. 250:1997;625-629.
-
(1997)
Eur J Biochem
, vol.250
, pp. 625-629
-
-
Hegg, E.L.1
Que, L.2
-
5
-
-
0039302669
-
Dioxygen activation by enzymes with mononuclear non-heme iron active sites
-
Que L., Ho R.Y.N. Dioxygen activation by enzymes with mononuclear non-heme iron active sites. Chem Rev. 96:1996;2607-2624.
-
(1996)
Chem Rev
, vol.96
, pp. 2607-2624
-
-
Que, L.1
Ho, R.Y.N.2
-
6
-
-
0009411657
-
Reactions of non-heme iron (II) centres with dioxygen in biology and medicine
-
Feig A.L., Lippard S.J. Reactions of non-heme iron (II) centres with dioxygen in biology and medicine. Chem Rev. 94:1994;759-805.
-
(1994)
Chem Rev
, vol.94
, pp. 759-805
-
-
Feig, A.L.1
Lippard, S.J.2
-
7
-
-
0000916977
-
Dioxygenases: Molecular structure and role in plant metabolism
-
Prescott A.G., John P. Dioxygenases: molecular structure and role in plant metabolism. Annu Rev Plant Physiol Plant Mol Biol. 47:1996;245-271.
-
(1996)
Annu Rev Plant Physiol Plant Mol Biol
, vol.47
, pp. 245-271
-
-
Prescott, A.G.1
John, P.2
-
8
-
-
0000658037
-
A dilemma of dioxygenases (or where biochemistry and molecular-biology fail to meet)
-
Prescott A.G. A dilemma of dioxygenases (or where biochemistry and molecular-biology fail to meet). J Exp Bot. 44:1993;849-861.
-
(1993)
J Exp Bot
, vol.44
, pp. 849-861
-
-
Prescott, A.G.1
-
9
-
-
0033529597
-
Evidence for 4-hydroxyproline in viral proteins - characterization of a viral prolyl 4-hydroxylase and its peptide substrates
-
Eriksson M., Myllyharju J., Tu H.M., Hellman M., Kivirikko K.I. Evidence for 4-hydroxyproline in viral proteins - characterization of a viral prolyl 4-hydroxylase and its peptide substrates. J Biol Chem. 274:1999;22131-22134.
-
(1999)
J Biol Chem
, vol.274
, pp. 22131-22134
-
-
Eriksson, M.1
Myllyharju, J.2
Tu, H.M.3
Hellman, M.4
Kivirikko, K.I.5
-
10
-
-
0031616949
-
Collagen hydroxylases and the protein disulfide isomerase subunit of prolyl 4-hydroxylases
-
Kivirikko K.I., Pihlajaniemi T. Collagen hydroxylases and the protein disulfide isomerase subunit of prolyl 4-hydroxylases. Adv Enzymol Relat Areas Mol Biol. 2:1998;325-400.
-
(1998)
Adv Enzymol Relat Areas Mol Biol
, vol.2
, pp. 325-400
-
-
Kivirikko, K.I.1
Pihlajaniemi, T.2
-
11
-
-
0030962028
-
Characterization of the iron- And 2-oxoglutarate-binding sites of human prolyl 4-hydroxylase
-
Myllyharju J., Kivirikko K.I. Characterization of the iron- and 2-oxoglutarate-binding sites of human prolyl 4-hydroxylase. EMBO J. 16:1997;1173-1180.
-
(1997)
EMBO J
, vol.16
, pp. 1173-1180
-
-
Myllyharju, J.1
Kivirikko, K.I.2
-
12
-
-
0028835709
-
Production of cephalosporin intermediates by feeding adipic acid to recombinant penicillium-chrysogenum strains expressing ring expansion activity
-
Crawford L., Stepan A.M., Mcada P.C., Rambosek J.A., Conder M.J., Vinci V.A., Reeves C.D. Production of cephalosporin intermediates by feeding adipic acid to recombinant penicillium-chrysogenum strains expressing ring expansion activity. Biotechnology. 13:1995;58-62.
-
(1995)
Biotechnology
, vol.13
, pp. 58-62
-
-
Crawford, L.1
Stepan, A.M.2
McAda, P.C.3
Rambosek, J.A.4
Conder, M.J.5
Vinci, V.A.6
Reeves, C.D.7
-
13
-
-
0011801104
-
Development of the regio- And stereospecific proline hydroxylases and their application
-
Shibasaki T., Mori H., Ozaki A. Development of the regio- and stereospecific proline hydroxylases and their application. J Synth Org Chem Japan. 57:1999;523-531.
-
(1999)
J Synth Org Chem Japan
, vol.57
, pp. 523-531
-
-
Shibasaki, T.1
Mori, H.2
Ozaki, A.3
-
14
-
-
0033551837
-
Product-substrate engineering by bacteria: Studies on clavaminate synthase, a trifunctional dioxygenase
-
Lloyd M.D., Merritt K.D., Lee V., Sewell T.J., Whason B., Baldwin J.E., Schofield C.J., Elson S.W., Baggaley K.H., Nicholson N.H. Product-substrate engineering by bacteria: studies on clavaminate synthase, a trifunctional dioxygenase. Tetrahedron. 55:1999;10201-10220.
-
(1999)
Tetrahedron
, vol.55
, pp. 10201-10220
-
-
Lloyd, M.D.1
Merritt, K.D.2
Lee, V.3
Sewell, T.J.4
Whason, B.5
Baldwin, J.E.6
Schofield, C.J.7
Elson, S.W.8
Baggaley, K.H.9
Nicholson, N.H.10
-
15
-
-
0027302013
-
18O labeled water into oxygenated products produced by the enzyme deacetoxy deacetylcephalosporin C-synthase
-
18O labeled water into oxygenated products produced by the enzyme deacetoxy deacetylcephalosporin C-synthase. Tetrahedron. 49:1993;7499-7518.
-
(1993)
Tetrahedron
, vol.49
, pp. 7499-7518
-
-
Baldwin, J.E.1
Adlington, R.M.2
Crouch, N.P.3
Pereira, I.A.C.4
-
17
-
-
0031469044
-
Proteins of the penicillin biosynthesis pathway
-
Schofield C.J., Baldwin J.E., Byford M.F., Clifton I., Hajdu J., Hensgens C., Roach P. Proteins of the penicillin biosynthesis pathway. Curr Opin Struct Biol. 7:1997;857-864.
-
(1997)
Curr Opin Struct Biol
, vol.7
, pp. 857-864
-
-
Schofield, C.J.1
Baldwin, J.E.2
Byford, M.F.3
Clifton, I.4
Hajdu, J.5
Hensgens, C.6
Roach, P.7
-
18
-
-
0029038392
-
Crystal structure of isopenicillin N synthase is first from a new structural family
-
Roach P.L., Clifton I.J., Fülöp V., Harlos K., Barton G.J., Hajdu J., Andersson I., Schofield C.J., Baldwin J.E. Crystal structure of isopenicillin N synthase is first from a new structural family. Nature. 7:1995;700-704.
-
(1995)
Nature
, vol.7
, pp. 700-704
-
-
Roach, P.L.1
Clifton, I.J.2
Fülöp, V.3
Harlos, K.4
Barton, G.J.5
Hajdu, J.6
Andersson, I.7
Schofield, C.J.8
Baldwin, J.E.9
-
19
-
-
0032552110
-
Structure of a cephalosporin synthase
-
The authors reveal the first structure of a 2-oxoglutarate-(2OG)-dependent oxygenase. Bidentate coordination of 2OG to iron is observed.
-
Valegard K., van Scheltinga A.C.T., Lloyd M.D., Hara T., Ramaswamy S., Perrakis A., Thompson A., Lee H.J., Baldwin J.E., Schofield C.J.et al. Structure of a cephalosporin synthase. Nature. 394:1998;805-809. The authors reveal the first structure of a 2-oxoglutarate-(2OG)-dependent oxygenase. Bidentate coordination of 2OG to iron is observed.
-
(1998)
Nature
, vol.394
, pp. 805-809
-
-
Valegard, K.1
Van Scheltinga, A.C.T.2
Lloyd, M.D.3
Hara, T.4
Ramaswamy, S.5
Perrakis, A.6
Thompson, A.7
Lee, H.J.8
Baldwin, J.E.9
Schofield, C.J.10
-
20
-
-
0023622631
-
Isolation of 2 novel intracellular beta-lactams and a novel dioxygenase cyclizing enzyme from Streptomyces clavuligerus
-
Elson S.W., Baggaley K.H., Gillett J., Holland S., Nicholson N.H., Sime J.T., Woroniecki S.R. Isolation of 2 novel intracellular beta-lactams and a novel dioxygenase cyclizing enzyme from Streptomyces clavuligerus. J Chem Soc Chem Commun. 1987;1736-1738.
-
(1987)
J Chem Soc Chem Commun
, pp. 1736-1738
-
-
Elson, S.W.1
Baggaley, K.H.2
Gillett, J.3
Holland, S.4
Nicholson, N.H.5
Sime, J.T.6
Woroniecki, S.R.7
-
21
-
-
0023632277
-
The roles of clavaminic acid and proclavaminic acid in clavulanic acid biosynthesis
-
Elson S.W., Baggaley K.H., Gillett J., Holland S., Nicholson N.H., Sime J.T., Woroniecki S.R. The roles of clavaminic acid and proclavaminic acid in clavulanic acid biosynthesis. J Chem Soc Chem Commun. 1987;1739-1740.
-
(1987)
J Chem Soc Chem Commun
, pp. 1739-1740
-
-
Elson, S.W.1
Baggaley, K.H.2
Gillett, J.3
Holland, S.4
Nicholson, N.H.5
Sime, J.T.6
Woroniecki, S.R.7
-
22
-
-
0027052392
-
2 isozymes of clavaminate synthase central to clavulanic acid formation - cloning and sequencing of both genes from Streptomyces clavuligerus
-
Marsh E.N., Chang M.D.T., Townsend C.A. 2 isozymes of clavaminate synthase central to clavulanic acid formation - cloning and sequencing of both genes from Streptomyces clavuligerus. Biochemistry. 31:1992;12648-12657.
-
(1992)
Biochemistry
, vol.31
, pp. 12648-12657
-
-
Marsh, E.N.1
Chang, M.D.T.2
Townsend, C.A.3
-
24
-
-
0030964827
-
The glutamine ligand in the ferrous iron active site of isopenicillin N synthase of Streptomyces jumonjinensis is not essential for catalysis
-
Landman O., Borovok I., Aharonowitz Y., Cohen G. The glutamine ligand in the ferrous iron active site of isopenicillin N synthase of Streptomyces jumonjinensis is not essential for catalysis. FEBS Lett. 405:1997;172-174.
-
(1997)
FEBS Lett
, vol.405
, pp. 172-174
-
-
Landman, O.1
Borovok, I.2
Aharonowitz, Y.3
Cohen, G.4
-
25
-
-
0031004173
-
Glutamine-330 is not essential for activity in isopenicillin N synthase from Aspergillus nidulans
-
Sami M., Brown T.J.N., Roach P.L., Schofield C.J., Baldwin J.E. Glutamine-330 is not essential for activity in isopenicillin N synthase from Aspergillus nidulans. FEBS Lett. 405:1997;191-194.
-
(1997)
FEBS Lett
, vol.405
, pp. 191-194
-
-
Sami, M.1
Brown, T.J.N.2
Roach, P.L.3
Schofield, C.J.4
Baldwin, J.E.5
-
26
-
-
0030044620
-
Purification and initial characterization of proline 4-hydroxylase from Streptomyces griseoviridus P8648: A 2-oxoacid, ferrous-dependent dioxygenase involved in etamycin biosynthesis
-
Lawrence C.C., Sobey W.J., Field R.A., Baldwin J.E., Schofield C.J. Purification and initial characterization of proline 4-hydroxylase from Streptomyces griseoviridus P8648: a 2-oxoacid, ferrous-dependent dioxygenase involved in etamycin biosynthesis. Biochem J. 313:1996;185-191.
-
(1996)
Biochem J
, vol.313
, pp. 185-191
-
-
Lawrence, C.C.1
Sobey, W.J.2
Field, R.A.3
Baldwin, J.E.4
Schofield, C.J.5
-
27
-
-
0030983568
-
Metal co-ordination environment of a Cu(II)-substituted alpha-keto acid-dependent dioxygenase that degrades the herbicide 2,4-D
-
Whiting A.K., Que L., Saari R.E., Hausinger R.P., Fredrick M.A., McCracken J. Metal co-ordination environment of a Cu(II)-substituted alpha-keto acid-dependent dioxygenase that degrades the herbicide 2,4-D. JACS. 119:1997;3413-3414.
-
(1997)
JACS
, vol.119
, pp. 3413-3414
-
-
Whiting, A.K.1
Que, L.2
Saari, R.E.3
Hausinger, R.P.4
Fredrick, M.A.5
McCracken, J.6
-
28
-
-
0032583527
-
Substrate binding to the alpha-ketoglutarate-dependent non-heme iron enzyme clavaminate synthase 2: Coupling mechanism of oxidative decarboxylation and hydroxylation
-
Zhou J., Gunsior M., Bachmann B.O., Townsend C.A., Solomon E.I. Substrate binding to the alpha-ketoglutarate-dependent non-heme iron enzyme clavaminate synthase 2: coupling mechanism of oxidative decarboxylation and hydroxylation. JACS. 120:1998;13539-13540.
-
(1998)
JACS
, vol.120
, pp. 13539-13540
-
-
Zhou, J.1
Gunsior, M.2
Bachmann, B.O.3
Townsend, C.A.4
Solomon, E.I.5
-
29
-
-
0032481388
-
Circular dichroism and magnetic circular dichroism spectroscopic studies of the non-heme ferrous active site in clavaminate synthase and its interaction with alpha-ketoglutarate cosubstrate
-
Together with [27,28], the first detailed solution study of the coordination chemistry of 2-oxoglutarate-dependent oxygenases.
-
Pavel E.G., Zhou J., Busby R.W., Gunsior M., Townsend C.A., Solomon E.I. Circular dichroism and magnetic circular dichroism spectroscopic studies of the non-heme ferrous active site in clavaminate synthase and its interaction with alpha-ketoglutarate cosubstrate. JACS. 120:1998;743-753. Together with [27,28], the first detailed solution study of the coordination chemistry of 2-oxoglutarate-dependent oxygenases.
-
(1998)
JACS
, vol.120
, pp. 743-753
-
-
Pavel, E.G.1
Zhou, J.2
Busby, R.W.3
Gunsior, M.4
Townsend, C.A.5
Solomon, E.I.6
-
30
-
-
0033529215
-
Role of the non heme Fe(II) center in the biosynthesis of the plant hormone ethylene
-
New mechanistic proposals for ACC oxidase.
-
Rocklin A.M., Tierney D.L., Kofman V., Brunhuber N.M.W., Hoffman B.M., Christoffersen R.E., Reich N.O., Lipscomb J.D., Que L. Role of the non heme Fe(II) center in the biosynthesis of the plant hormone ethylene. Proc Natl Acad Sci USA. 96:1999;7905-7909. New mechanistic proposals for ACC oxidase.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7905-7909
-
-
Rocklin, A.M.1
Tierney, D.L.2
Kofman, V.3
Brunhuber, N.M.W.4
Hoffman, B.M.5
Christoffersen, R.E.6
Reich, N.O.7
Lipscomb, J.D.8
Que, L.9
-
31
-
-
0033566802
-
Crystal structure of an aromatic ring opening dioxygenase LigAB, a protocatechuate 4,5-dioxygenase, under aerobic conditions
-
This paper provides the first structure of a class II extradiol dioxygenase, defining them as a distinct structural family from the class II enzymes.
-
Sugimoto K., Senda T., Aoshima H., Masai E., Fukuda M., Mitsui Y. Crystal structure of an aromatic ring opening dioxygenase LigAB, a protocatechuate 4,5-dioxygenase, under aerobic conditions. Structure. 7:1999;953-965. This paper provides the first structure of a class II extradiol dioxygenase, defining them as a distinct structural family from the class II enzymes.
-
(1999)
Structure
, vol.7
, pp. 953-965
-
-
Sugimoto, K.1
Senda, T.2
Aoshima, H.3
Masai, E.4
Fukuda, M.5
Mitsui, Y.6
-
32
-
-
0033556265
-
An archetypical extradiol-cleaving catecholic dioxygenase: The crystal structure of catechol 2,3-dioxygenase (metapyrocatechase) from Pseudomonas putida mt-2
-
Kita A., Kita S., Fujisawa I., Inaka K., Ishida T., Horiike K., Nozaki M., Miki K. An archetypical extradiol-cleaving catecholic dioxygenase: the crystal structure of catechol 2,3-dioxygenase (metapyrocatechase) from Pseudomonas putida mt-2. Structure. 7:1999;25-34.
-
(1999)
Structure
, vol.7
, pp. 25-34
-
-
Kita, A.1
Kita, S.2
Fujisawa, I.3
Inaka, K.4
Ishida, T.5
Horiike, K.6
Nozaki, M.7
Miki, K.8
-
33
-
-
0030008087
-
3-dimensional structures of free-form and 2 substrate complexes of an extradiol ring-cleavage type dioxygenase, the bphc enzyme from Pseudomonas sp strain KKS102
-
Senda T., Sugiyama K., Narita H., Yamamoto T., Kimbara K., Fukuda M., Satao M., Yano K., Mitsui Y. 3-dimensional structures of free-form and 2 substrate complexes of an extradiol ring-cleavage type dioxygenase, the bphc enzyme from Pseudomonas sp strain KKS102. J Mol Biol. 255:1996;735-752.
-
(1996)
J Mol Biol
, vol.255
, pp. 735-752
-
-
Senda, T.1
Sugiyama, K.2
Narita, H.3
Yamamoto, T.4
Kimbara, K.5
Fukuda, M.6
Satao, M.7
Yano, K.8
Mitsui, Y.9
-
34
-
-
0028862027
-
Crystal-structure of the biphenyl-cleaving extradiol dioxygenase from a PCB-degrading Pseudomonad
-
Han S., Eltis L.D., Timmis K.N., Muchmore S.W., Bolin J.T. Crystal-structure of the biphenyl-cleaving extradiol dioxygenase from a PCB-degrading Pseudomonad. Science. 270:1995;976-980.
-
(1995)
Science
, vol.270
, pp. 976-980
-
-
Han, S.1
Eltis, L.D.2
Timmis, K.N.3
Muchmore, S.W.4
Bolin, J.T.5
-
35
-
-
0032524127
-
Structure of an aromatic-ring-hydroxylating dioxygenase-naphthalene 1,2-dioxygenase
-
This remarkable crystal structure of napthalene dioxygenase, which contains Rieske and mononuclear iron centres, provides a structural framework for mechanistic studies.
-
Kauppi B., Lee K., Carredano E., Parales R.E., Gibson D.T., Eklund H., Ramaswamy S. Structure of an aromatic-ring-hydroxylating dioxygenase-naphthalene 1,2-dioxygenase. Structure. 6:1998;571-586. This remarkable crystal structure of napthalene dioxygenase, which contains Rieske and mononuclear iron centres, provides a structural framework for mechanistic studies.
-
(1998)
Structure
, vol.6
, pp. 571-586
-
-
Kauppi, B.1
Lee, K.2
Carredano, E.3
Parales, R.E.4
Gibson, D.T.5
Eklund, H.6
Ramaswamy, S.7
-
36
-
-
0031303781
-
Crystal structure of the catalytic domain of human phenylalanine hydroxylase reveals the structural basis for phenylketonuria
-
Erlandsen H., Fusetti F., Martinez A., Hough E., Flatmark T., Stevens R.C. Crystal structure of the catalytic domain of human phenylalanine hydroxylase reveals the structural basis for phenylketonuria. Nat Struct Biol. 4:1997;995-1000.
-
(1997)
Nat Struct Biol
, vol.4
, pp. 995-1000
-
-
Erlandsen, H.1
Fusetti, F.2
Martinez, A.3
Hough, E.4
Flatmark, T.5
Stevens, R.C.6
-
37
-
-
0032506049
-
Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 angstrom resolution
-
Erlandsen H., Flatmark T., Stevens R.C., Hough E. Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 angstrom resolution. Biochemistry. 37:1998;15638-15646.
-
(1998)
Biochemistry
, vol.37
, pp. 15638-15646
-
-
Erlandsen, H.1
Flatmark, T.2
Stevens, R.C.3
Hough, E.4
-
38
-
-
0032479302
-
Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuria
-
Fusetti F., Erlandsen H., Flatmark T., Stevens R.C. Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuria. J Biol Chem. 273:1998;16962-16967.
-
(1998)
J Biol Chem
, vol.273
, pp. 16962-16967
-
-
Fusetti, F.1
Erlandsen, H.2
Flatmark, T.3
Stevens, R.C.4
-
39
-
-
0032578427
-
Crystal structure of tyrosine hydroxylase with bound cofactor analogue and iron at 2.3 angstrom resolution: Self-hydroxylation of Phe300 and the pterin-binding site
-
Goodwill K.E., Sabatier C., Stevens R.C. Crystal structure of tyrosine hydroxylase with bound cofactor analogue and iron at 2.3 angstrom resolution: self-hydroxylation of Phe300 and the pterin-binding site. Biochemistry. 37:1998;13437-13445.
-
(1998)
Biochemistry
, vol.37
, pp. 13437-13445
-
-
Goodwill, K.E.1
Sabatier, C.2
Stevens, R.C.3
-
40
-
-
0031010420
-
Crystal structure of tyrosine hydroxylase at 2.3 angstrom and its implications for inherited neurodegenerative diseases
-
Goodwill K.E., Sabatier C., Marks C., Raag R., Fitzpatrick P.F., Stevens R.C. Crystal structure of tyrosine hydroxylase at 2.3 angstrom and its implications for inherited neurodegenerative diseases. Nat Struct Biol. 4:1997;578-585.
-
(1997)
Nat Struct Biol
, vol.4
, pp. 578-585
-
-
Goodwill, K.E.1
Sabatier, C.2
Marks, C.3
Raag, R.4
Fitzpatrick, P.F.5
Stevens, R.C.6
-
41
-
-
0028067892
-
Structure of protocatechuate 3,4-dioxygenase from Pseudomonas aeruginosa at 2.15 angstrom resolution
-
Ohlendorf D.H., Orville A.M., Lipscomb J.D. Structure of protocatechuate 3,4-dioxygenase from Pseudomonas aeruginosa at 2.15 angstrom resolution. J Mol Biol. 244:1994;586-608.
-
(1994)
J Mol Biol
, vol.244
, pp. 586-608
-
-
Ohlendorf, D.H.1
Orville, A.M.2
Lipscomb, J.D.3
-
42
-
-
0030874393
-
Structures of competitive inhibitor complexes of protocatechuate 3,4-dioxygenase: Multiple exogenous ligand binding orientations within the active site
-
Orville A.M., Elango N., Lipscomb J.D., Ohlendorf D.H. Structures of competitive inhibitor complexes of protocatechuate 3,4-dioxygenase: multiple exogenous ligand binding orientations within the active site. Biochemistry. 36:1997;10039-10051.
-
(1997)
Biochemistry
, vol.36
, pp. 10039-10051
-
-
Orville, A.M.1
Elango, N.2
Lipscomb, J.D.3
Ohlendorf, D.H.4
-
43
-
-
0030954878
-
Crystal structure and resonance Raman studies of protocatechuate 3,4- dioxygenase complexed with 3,4-dihydroxyphenylacetate
-
Elgren T.E., Orville A.M., Kelly K.A., Lipscomb J.D., Ohlendorf D.H., Que L. Crystal structure and resonance Raman studies of protocatechuate 3,4- dioxygenase complexed with 3,4-dihydroxyphenylacetate. Biochemistry. 36:1997;11504-11513.
-
(1997)
Biochemistry
, vol.36
, pp. 11504-11513
-
-
Elgren, T.E.1
Orville, A.M.2
Kelly, K.A.3
Lipscomb, J.D.4
Ohlendorf, D.H.5
Que, L.6
-
45
-
-
0027246677
-
The 3-dimensional structure of an arachidonic-acid 15-lipoxygenase
-
Boyington J.C., Gaffney B.J., Amzel L.M. The 3-dimensional structure of an arachidonic-acid 15-lipoxygenase. Science. 260:1993;1482-1486.
-
(1993)
Science
, vol.260
, pp. 1482-1486
-
-
Boyington, J.C.1
Gaffney, B.J.2
Amzel, L.M.3
-
46
-
-
0029740369
-
Crystal-structure of soybean lipoxygenase Ll at 1.4 angstrom resolution
-
Minor W., Steczko J., Stec B., Otwinowski Z., Bolin J.T., Walter R., Axelrod B. Crystal-structure of soybean lipoxygenase Ll at 1.4 angstrom resolution. Biochemistry. 35:1996;10687-10701.
-
(1996)
Biochemistry
, vol.35
, pp. 10687-10701
-
-
Minor, W.1
Steczko, J.2
Stec, B.3
Otwinowski, Z.4
Bolin, J.T.5
Walter, R.6
Axelrod, B.7
-
47
-
-
0030736867
-
The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity
-
Gillmor S.A., Villasenor A., Fletterick R., Sigal E., Browner M.F. The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity. Nat Struct Biol. 4:1997;1003-1009.
-
(1997)
Nat Struct Biol
, vol.4
, pp. 1003-1009
-
-
Gillmor, S.A.1
Villasenor, A.2
Fletterick, R.3
Sigal, E.4
Browner, M.F.5
-
49
-
-
0000296163
-
Peptide deformylase: A new type of mononuclear iron protein
-
Rajagopalan P.T.R., Yu X.C., Pei D.H. Peptide deformylase: a new type of mononuclear iron protein. JACS. 119:1997;12418-12419.
-
(1997)
JACS
, vol.119
, pp. 12418-12419
-
-
Rajagopalan, P.T.R.1
Yu, X.C.2
Pei, D.H.3
-
50
-
-
0032575507
-
Oxygen-mediated inactivation of peptide deformylase
-
Rajagopalan P.T.R., Pei D. Oxygen-mediated inactivation of peptide deformylase. J Biol Chem. 273:1998;22305-22310.
-
(1998)
J Biol Chem
, vol.273
, pp. 22305-22310
-
-
Rajagopalan, P.T.R.1
Pei, D.2
-
51
-
-
0029057216
-
Galactose-1-phosphate uridylyltransferase from Escherichia coli, a zinc and iron metalloenzyme
-
Ruzicka F.J., Wedekind J.E., Kim J.M., Rayment I., Frey P.A. Galactose-1-phosphate uridylyltransferase from Escherichia coli, a zinc and iron metalloenzyme. Biochemistry. 34:1995;5610-5617.
-
(1995)
Biochemistry
, vol.34
, pp. 5610-5617
-
-
Ruzicka, F.J.1
Wedekind, J.E.2
Kim, J.M.3
Rayment, I.4
Frey, P.A.5
-
52
-
-
0030947388
-
Structure of isopenicillin N synthase complexed to substrate and the mechanism of penicillin formation
-
Roach P.L., Clifton I.J., Shibata N., Hajdu J., Schofield C.J., Baldwin J.E. Structure of isopenicillin N synthase complexed to substrate and the mechanism of penicillin formation. Nature. 387:1997;827-830.
-
(1997)
Nature
, vol.387
, pp. 827-830
-
-
Roach, P.L.1
Clifton, I.J.2
Shibata, N.3
Hajdu, J.4
Schofield, C.J.5
Baldwin, J.E.6
-
54
-
-
0033152216
-
An enzyme controlled by light: The molecular mechanism of photoreactivity in nitrile hydratase
-
••], this paper reveals the remarkable post-translational modifications at the active site of nitrile hydratase.
-
••], this paper reveals the remarkable post-translational modifications at the active site of nitrile hydratase.
-
(1999)
Trends Biotechnol
, vol.17
, pp. 244-249
-
-
Endo, I.1
Odaka, M.2
Yohda, M.3
-
55
-
-
0016751962
-
A kinetic study of thymine 7-hydroxylase from Neurospora crassa
-
Holme E. A kinetic study of thymine 7-hydroxylase from Neurospora crassa. Biochemistry. 14:1975;4999-5003.
-
(1975)
Biochemistry
, vol.14
, pp. 4999-5003
-
-
Holme, E.1
-
56
-
-
0020488069
-
A stereochemical concept for the catalytic mechanism of prolyl-4-hydroxylase - applicability to classification and design of inhibitors
-
Hanauskeabel H.M., Gunzler V. A stereochemical concept for the catalytic mechanism of prolyl-4-hydroxylase - applicability to classification and design of inhibitors. J Theoret Biol. 94:1982;421-455.
-
(1982)
J Theoret Biol
, vol.94
, pp. 421-455
-
-
Hanauskeabel, H.M.1
Gunzler, V.2
-
57
-
-
49249148472
-
α-Ketoglutarate dependent dioxygenases: A mechanism for prolyl-hydroxylase action
-
Siegel B. α-Ketoglutarate dependent dioxygenases: a mechanism for prolyl-hydroxylase action. Bioorg Chem. 8:1979;2129-2226.
-
(1979)
Bioorg Chem
, vol.8
, pp. 2129-2226
-
-
Siegel, B.1
-
58
-
-
0033574483
-
Studies on the active site of deacetoxycephalosporin C synthase
-
Lloyd M.D., Lee H.J., Harlos K., Zhang Z.H., Baldwin J.E., Schofield C.J., Charnock J.M., Garner C.D., Hara T., van Scheltinga A.C.T.et al. Studies on the active site of deacetoxycephalosporin C synthase. J Mol Biol. 287:1999;943-960.
-
(1999)
J Mol Biol
, vol.287
, pp. 943-960
-
-
Lloyd, M.D.1
Lee, H.J.2
Harlos, K.3
Zhang, Z.H.4
Baldwin, J.E.5
Schofield, C.J.6
Charnock, J.M.7
Garner, C.D.8
Hara, T.9
Van Scheltinga, A.C.T.10
-
59
-
-
0033608080
-
Mechanism-based inactivation of the human prolyl-4-hydroxylase by 5-oxaproline-containing peptides: Evidence for a prolyl radical intermediate
-
Wu M., Moon H.S., Begley T.P., Myllyharju J., Kivirikko K.I. Mechanism-based inactivation of the human prolyl-4-hydroxylase by 5-oxaproline-containing peptides: evidence for a prolyl radical intermediate. JACS. 121:1999;587-588.
-
(1999)
JACS
, vol.121
, pp. 587-588
-
-
Wu, M.1
Moon, H.S.2
Begley, T.P.3
Myllyharju, J.4
Kivirikko, K.I.5
-
60
-
-
0029802674
-
Heterologous expression and site-directed mutagenesis of the 1-aminocyclopropane-1-carboxylate oxidase from kiwi fruit
-
Lay V.J., Prescott A.G., Thomas P.G., John P. Heterologous expression and site-directed mutagenesis of the 1-aminocyclopropane-1-carboxylate oxidase from kiwi fruit. Eur J Biochem. 242:1996;228-234.
-
(1996)
Eur J Biochem
, vol.242
, pp. 228-234
-
-
Lay, V.J.1
Prescott, A.G.2
Thomas, P.G.3
John, P.4
-
61
-
-
0031455762
-
Metal-catalyzed oxidation and mutagenesis studies on the iron(II) binding site of 1-aminocyclopropane-1-carboxylate oxidase
-
Zhang Z.H., Barlow J.N., Baldwin J.E., Schofield C.J. Metal-catalyzed oxidation and mutagenesis studies on the iron(II) binding site of 1-aminocyclopropane-1-carboxylate oxidase. Biochemistry. 36:1997;15999-16007.
-
(1997)
Biochemistry
, vol.36
, pp. 15999-16007
-
-
Zhang, Z.H.1
Barlow, J.N.2
Baldwin, J.E.3
Schofield, C.J.4
-
62
-
-
0031767875
-
Enzymatic cleavage of aromatic rings: Mechanistic aspects of the catechol dioxygenases and later enzymes of bacterial oxidative cleavage pathways
-
Bugg T.D.H., Winfield C.J. Enzymatic cleavage of aromatic rings: mechanistic aspects of the catechol dioxygenases and later enzymes of bacterial oxidative cleavage pathways. Nat Prod Reps. 15:1998;513-530.
-
(1998)
Nat Prod Reps
, vol.15
, pp. 513-530
-
-
Bugg, T.D.H.1
Winfield, C.J.2
-
63
-
-
0029836348
-
Cis-trans isomerization of a cyclopropyl radical trap catalyzed by extradiol catechol dioxygenases: Evidence for a semiquinone intermediate
-
Spence E.L., Langley G.J., Bugg T.D.H. Cis-trans isomerization of a cyclopropyl radical trap catalyzed by extradiol catechol dioxygenases: evidence for a semiquinone intermediate. JACS. 118:1996;8336-8343.
-
(1996)
JACS
, vol.118
, pp. 8336-8343
-
-
Spence, E.L.1
Langley, G.J.2
Bugg, T.D.H.3
-
64
-
-
0028835678
-
Mechanism of extradiol catechol dioxygenases - evidence for a lactone intermediate in the 2,3-dihydroxyphenylpropionate 1,2-dioxygenase reaction
-
Sanvoisin J., Langley G.J., Bugg T.D.H. Mechanism of extradiol catechol dioxygenases - evidence for a lactone intermediate in the 2,3-dihydroxyphenylpropionate 1,2-dioxygenase reaction. JACS. 117:1995;7836-7837.
-
(1995)
JACS
, vol.117
, pp. 7836-7837
-
-
Sanvoisin, J.1
Langley, G.J.2
Bugg, T.D.H.3
-
65
-
-
0030839644
-
Stereochemical course of the conversion of alpha-ketoisocaproate to beta-hydroxyisovalerate by soluble, recombinant mammalian 4-hydroxyphenylpyruvate dioxygenase
-
Crouch N.P., Adlington R.M., Baldwin J.E., Lee M.H., MacKinnon C.H., Paul D.R. Stereochemical course of the conversion of alpha-ketoisocaproate to beta-hydroxyisovalerate by soluble, recombinant mammalian 4-hydroxyphenylpyruvate dioxygenase. Tetrahedron. 53:1997;10827-10840.
-
(1997)
Tetrahedron
, vol.53
, pp. 10827-10840
-
-
Crouch, N.P.1
Adlington, R.M.2
Baldwin, J.E.3
Lee, M.H.4
MacKinnon, C.H.5
Paul, D.R.6
-
66
-
-
0000783838
-
Pterin-dependent amino acid hydroxylases
-
Kappock T.J., Caradonna J.P. Pterin-dependent amino acid hydroxylases. Chem Rev. 96:1996;2659-2756.
-
(1996)
Chem Rev
, vol.96
, pp. 2659-2756
-
-
Kappock, T.J.1
Caradonna, J.P.2
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