Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase

Nature Structural Biology

Volumn 7, Issue 2, 2000, Pages 127-133

  Zhang, Zhihong ^a   Ren, Jingshan ^b   Stammers, David K ^b   Baldwin, Jack E ^a   Marios, Karl ^b   Schofield, Christopher J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; ADICILLIN; BETA LACTAM ANTIBIOTIC; CLAVULANIC ACID; IRON; ISOPENICILLIN N; NONHEME IRON PROTEIN; OXIDOREDUCTASE; OXYGENASE;

ARTICLE; CHEMICAL REACTION; CRYSTAL STRUCTURE; CYCLIZATION; DRUG STRUCTURE; ENZYME ANALYSIS; ENZYME SPECIFICITY; ENZYME STRUCTURE; HYDROXYLATION; PRIORITY JOURNAL; REACTION ANALYSIS; STRUCTURE ANALYSIS;

ARGININE; AZA COMPOUNDS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; IRON; ISOENZYMES; KETOGLUTARIC ACIDS; MIXED FUNCTION OXYGENASES; MODELS, MOLECULAR; OXYGEN; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

EID: 0033981009     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/72398     Document Type: Article

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