Nociceptive response to innocuous mechanical stimulation is mediated via myelinated afferents and NK-1 receptor activation in a rat model of neuropathic pain

Experimental Neurology

Volumn 186, Issue 2, 2004, Pages 173-197

  Pitcher, Graham M ^a   Henry, James L ^b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Chronic pain; Contralateral; CP 100,263; CP 99,994; Dorsal horn; Electrophysiology; Neuropathic pain; NK 1 receptor; Nociception; Spinal cord; Substance P; Wide dynamic range neuron

Indexed keywords

3 (2 METHOXYBENZYLAMINO) 2 PHENYLPIPERIDINE;

AFTERDISCHARGE; ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; HINDLIMB; MALE; MECHANICAL STIMULATION; MYELINATION; NERVE CELL EXCITABILITY; NEUROCHEMISTRY; NEUROPATHIC PAIN; NEUROPHYSIOLOGY; NOCICEPTIVE STIMULATION; NONHUMAN; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; RAT; RECEPTIVE FIELD; RECEPTOR INTRINSIC ACTIVITY; SCIATIC NERVE; SPECIES COMPARISON;

AFFERENT PATHWAYS; ANIMALS; CONSTRICTION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTROPHYSIOLOGY; EVOKED POTENTIALS; FUNCTIONAL LATERALITY; HINDLIMB; MALE; NERVE FIBERS, MYELINATED; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; PERIPHERAL NERVOUS SYSTEM DISEASES; PHYSICAL STIMULATION; PIPERIDINES; POSTERIOR HORN CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROKININ-1; SCIATIC NERVE; SPINAL CORD; TIME FACTORS;

EID: 1542617763     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.expneurol.2003.10.019     Document Type: Article

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