NSAID-induced cyclooxygenase inhibition differentially depresses long-lasting versus brief synaptically-elicited responses of rat spinal dorsal horn neurons in vivo

Pain

Volumn 82, Issue 2, 1999, Pages 173-186

  Pitcher, Graham M ^a   Henry, James L ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Arachidonic acid; Indomethacin; Nociception; Non nociceptive neuron; Pain; Prostaglandin; Spinal cord; Wide dynamic range neuron

Indexed keywords

ICOSANOID; INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN SYNTHASE;

AFTERDISCHARGE; ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTROSTIMULATION; ENZYME INHIBITION; EXCITATION; INTRATHECAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MECHANICAL STIMULATION; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SIGNAL TRANSDUCTION; SPINAL CORD DORSAL HORN; SPINAL CORD STIMULATION; THERMAL STIMULATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CYCLOOXYGENASE INHIBITORS; DEPRESSION, CHEMICAL; DRUG EVALUATION, PRECLINICAL; ELECTRIC STIMULATION; HEAT; INDOMETHACIN; MALE; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; SKIN; SPINAL CORD; STRESS, MECHANICAL; SYNAPTIC TRANSMISSION;

EID: 0033049580     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(99)00050-0     Document Type: Article

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