Spinal expression of mRNA for immediate early genes in a model of chronic pain

Acta Physiologica Scandinavica

Volumn 161, Issue 4, 1997, Pages 517-525

  Delander, G E ^a   Schott E ^b   Brodin, E ^b   Fredholm, B B ^b  

^a OREGON STATE UNIVERSITY   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Allodynia; Fos; Gene expression; In situ hybridization; Jun; Motor neurons; Nerve injury; Spinal cord

Indexed keywords

MESSENGER RNA;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC PAIN; CONTROLLED STUDY; GENE EXPRESSION; IMMEDIATE EARLY GENE; IN SITU HYBRIDIZATION; MALE; NERVE INJURY; NONHUMAN; ONCOGENE C JUN; PRIORITY JOURNAL; RAT;

EID: 0030687923     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.1997.00260.x     Document Type: Article

References (54)

1. Abbadie, C., Lombard, M.C., Morain, F. & Besson, J.M. 1992. Fos-like immunoreactivity in the rat superficial dorsal horn induced by formalin injection in the forepaw: effects of dorsal rhizotomies. Brain Res 578, 17-25.
2. Abbadie, C., Taylor, B.K., Peterson, M.A. & Basbaum, A.I. 1997. Differential contribution of the two phases of the formalin test to the pattern of c-fos expression in the rat spinal cord: studies with remifentalin and lidocaine. Pain 69, 101-110.
3. Altschul, S.F., Gish, W., Miller, W., Myers, E.W. & Lipman, D.J. 1990. Basic local alignment search tool. J Mol Biol 215, 403-410.
4. Behbehani, M.M. & Dollberg-Stolik, O. 1994. Partial sciatic nerve ligation results in an enlargement of the receptive field and enhancement of the response of dorsal horn neurons to noxious stimulation by an adenosine agonist. Pain 58, 421-428.
5. Bennett, G.J. 1994. Animal models of neuropathic pain. Prog Pain Res Management 1, 495-510.
6. Bennett, G.J. & Xie, Y.K. 1988. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 33, 87-107.
7. Bullitt, E. 1991. Somatotopy of spinal nociceptive processing. J Comp Neurol 312, 279-290.
8. DeLeo, J.A., Coombs, D.W. & McCarthy, L.E. 1991. Differential c-fos-like protein expression in mechanically versus chemically induced visceral nociception. Mol Brain Res 11, 167-170.
9. DeLeo, J.A., Coombs, D.W., Willenbring, S., Colburn, R.W., Fromm, C., Wagner, R. & Twitchell, B.B. 1994. Characterization of a neuropathic pain model: sciatic cryoneurolysis in the rat. Pain 56, 9-16.
10. Dougherty, P.M., Garrison, C.J. & Carlton, S.M. 1992. Differential influence of local anesthetic upon two models of experimentally induced peripheral mononeuropathy in the rat. Brain Res 570, 109-115.
11. Draisci, G. & Iadarola, M.J. 1989. Temporal analysis of increases in c-fos, preprodynorphin and preproenkephalin mRNAs in rat spinal cord. Mol Brain Res 6, 31-37.
12. Dray, A., Urban, L. & Dickenson, A. 1994. Pharmacology of chronic pain. Trends Pharmacol Sci 15, 190-197.
13. Dubner, R. & Ruda, M.A. 1992. Activity-dependent neuronal plasticity following tissue injury and inflammation. Trends Neurosci 15, 96-103.
14. el-Bohy, A. & LaMotte, C.C. 1993. Deafferentation-induced changes in neuropeptides of the adult rat dorsal horn following pronase injection of the sciatic nerve. J Comp Neurol 336, 545-554.
15. Hammond, D.L., Presley, R., Gogas, K.R. & Basbaum, A.I. 1992. Morphine or U-50, 488 suppresses Fos protein-like immunoreactivity in the spinal cord and nucleus tractus solitarii evoked by a noxious visceral stimulus in the rat. J Comp Neurol 315, 244-253.
16. Herdegen, T., Fiallos-Estrada, C.E., Bravo, R. & Zimmermann, M. 1993. Colocalisation and covariation of c-JUN transcription factor with galanin in primary afferent neurons and with CGRP in spinal motoneurons following transection of rat sciatic nerve. Mol Brain Res 17, 147-154.
17. Herdegen, T., Fiallos-Estrada, C.E., Schmid, W., Bravo, R. & Zimmermann, M. 1992. The transcription factors c-JUN, JUN D and CREB, but not FOS and KROX-24, are differentially regulated in axotomized neurons following transection of rat sciatic nerve. Mol Brain Res 14, 155-165.
18. Herdegen, T., Kovary, K., Leah, J. & Bravo, R. 1991. Specific temporal and spatial distribution of JUN, FOS, and KROX-24 proteins in spinal neurons following noxious transsynaptic stimulation. J Comp Neurol 313, 178-191.
19. Hökfelt, T., Zhang, X. & Wiesenfeld-Hallin, Z. 1994. Messenger plasticity in primary sensory neurons following axotomy and its functional implications. Trends Neurosci 17, 22-30.
20. Hughes, P. & Dragunow, M. 1995. Induction of immediate-early genes and the control of neurotransmitter-regulated gene expression within the nervous system. Pharmacol Rev 47, 133-178.
21. Hunt, S.P., Pini, A. & Evan, G. 1987. Induction of c-fos-like protein in spinal cord neurons following sensory stimulation. Nature 328, 632-634.
22. Jones, S.L. & Light, A.R. 1990. Electrical stimulation in the medullary nucleus raphe magnus inhibits noxious heat-evoked fos protein-like immunoreactivity in the rat lumbar spinal cord. Brain Res 530, 335-338.
23. Kim, S.H. & Chung, J.M. 1992. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 50, 355-363.
24. Kim, K.J., Yoon, Y.W., Lee, B.H. & Chung, J.M. 1994. Comparison of animal models for peripheral neuropathic pain. Neurosci Abstr 20, 761.
25. Lamph, W.W., Wamsley, P., Sassone-Corsi, P. & Verma, I.M. 1988. Induction of proto-oncogene jun/AP-1 by serum and TPA. Nature 334, 629-631.
26. Lanteri-Minet, M., de Pommery, J., Herdegen, T., Weil-Fugazza, J., Bravo, R. & Menetrey, D. 1993. Differential time course and spatial expression of Fos, Jun, and Krox-24 proteins in spinal cord of rats undergoing subacute or chronic somatic inflammation. J Comp Neurol 333, 223-235.
27. Leah, J.D., Herdegen, T. & Bravo, R. 1991. Selective expression of Jun proteins following axotomy and axonal transport block in peripheral nerves in the rat: evidence for a role in the regeneration process. Brain Res 566, 198-207.
28. Lee, B.H., Yoon, Y.W., Chung, K. & Chung, J.M. 1994. Changes in sympathetic innervation to the sensory ganglia in several neuropathic pain models. Neurosci Abstr 20, 760.
29. Malmberg, A.B. & Basbaum, A.I. 1995. Anatomical and behavioral consequences of partial sciatic nerve injury in the mouse. Am Pain Soc Abstr A-110.
30. Menétrey, D., Gannon, A., Levine, J.D. & Basbaum, A.I. 1989. Expression of c-fos protein in interneurons and projection neurons of the rat spinal cord in response to noxious somatic, articular, and visceral stimulation. J Comp Neurol 285, 177-195.
31. Milbrandt, J. 1987. A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor. Science 238, 797-799.
32. Molander, C., Hongpaisan, J. & Persson, J.K. 1994. Distribution of c-fos expressing dorsal horn neurons after electrical stimulation of low threshold sensory fibers in the chronically injured sciatic nerve. Brain Res 644, 74-82.
33. Moratalla, R., Vickers, E.A., Robertson, H.A., Cochran, B.H. & Graybiel, A.M. 1993. Coordinate expression of c-fos and jun B is induced in the rat striatum by cocaine. J Neurosci 13, 423-433.
34. Morgan, M.M., Gogas, K.R. & Basbaum, A.I. 1994. Diffuse noxious inhibitory controls reduce the expression of noxious stimulus-evoked Fos-like immunoreactivity in the superficial and deep laminae of the rat spinal cord. Pain 56, 347-352.
35. Munglani, R. & Hunt, S.P. 1995. Molecular biology of pain. Br J Anaesthesia 75, 186-192.
36. Na, H.S., Yoon, Y.W. & Chung, J.M. 1996. Both motor and sensory abnormalitites contribute to changes in foot posture in an experimental rat neuropathic model. Pain 67, 173-178.
37. Noguchi, K., Dubner, R. & Ruda, M.A. 1992. Preproenkephalin mRNA in spinal dorsal horn neurons is induced by peripheral inflammation and is co-localized with Fos and Fos-related proteins. Neuroscience 46, 561-570.
38. Pelto-Huikko, M., Dagerlind, Å., Ceccatelli, S. & Hökfelt, T. 1991. The immediate-early genes c-fos and c-jun are differentially expressed in the rat adrenal gland after capsaicin treatment. Neurosci Lett 126, 163-166.
39. Presley, R.W., Menetrey, D., Levine, J.D. & Basbaum, A.I. 1990. Systemic morphine suppresses noxious stimulus-evoked fos protein-like immunoreactivity in the rat spinal cord. J Neurosci 10, 323-335.
40. Ryder, K., Lau, L.F. & Nathans, D. 1988. A gene activated by growth factors is related to the oncogene v-jun. Proc Natl Acad Sci USA 85, 1487-1491.
41. Schött, E., Berge, O.G., Angeby-Möller, K., Hammarström, G., Dalsgaard, C.J. & Brodin, E. 1994. Weight bearing as an objective measure of arthritic pain in the rat. J Pharmacol Toxicol Methods 31, 79-83.
42. Seltzer, Z., Dubner, R. & Shir, Y. 1990. A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain 43, 205-218.
43. Sheng, M. & Greenberg, M.E. 1990. The regulation and function of c-fos and other immediate early genes in the nervous system. Neuron 4, 477-485.
44. Sugimoto, T., Yoshida, A., Nishijima, K. & Ichikawa, H. 1995. Disruption and restoration of dorsal horn sensory map after peripheral nerve crush and regeneration. Pain 63, 49-54.
45. Tallarida, R.J & Murray, R.B 1981. Manual of Pharmacologic Calculation. Springer-Verlag, New York.
46. Tölle, T.R., Herdegen, T., Schadrack, J., Bravo, R., Zimmermann, M. & Zieglgänsberger, W. 1994. Application of morphine prior to noxious stimulation differentially modulates expression of Fos, Jun and Krox-24 proteins in rat spinal cord neurons. Neuroscience 58, 305-321.
47. Traub, R.J., Pechman, P., Iadarola, M.J. & Gebhart, G.F. 1992. Fos-like proteins in the lumbosacral spinal cord following noxious and non-noxious colorectal distention in the rat. Pain 49, 393-403.
48. Wall, P.D., Devor, M., Inbal, R., Scadding, J.W., Schonfield, D., Seltzer, Z. & Tomkiewicz, M.M. 1979. Axotomy following peripheral nerve lesions: experimental anasethesia dolorosa. Pain 7, 103-113.
49. Wiesenfeld, Z. & Lindblom, U. 1980. Behavioral and electrophysiological effects of various types of peripheral nerve lesions in the rat: a comparison of possible models of chronic pain. Pain 8, 285-298.
50. Wisden, W., Errington, M.L., Williams, S., Dunnitt, S.B., Waters, C., Hitchcock, D., Evan, G., Bliss, T.V.P. & Hunt, S.P. 1990. Differential expression of immediate early genes in the hippocampus and spinal cord. Neuron 4, 603-614.
51. Wu, W., Li, Y. & Schinco, F.P. 1994. Expression of c-jun and neuronal nitric oxide synthase in rat spinal motoneurons following axonal injury. Neurosci Lett 179, 157-161.
52. Zhang, R.X., Wang, R., Chen, J.Y. & Qiao, J.T. 1994. Effects of descending inhibitory systems on the c-Fos expression in the rat spinal cord during formalin-induced noxious stimulation. Neuroscience 58, 299-304.
53. Zimmermann, M. 1983. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16, 109-110.
54. Zimmerman, M. & Herdegen, T. 1996. Plasticity of the nervous system at the systemic, cellular and molecular levels: a mechanism of chronic pain and hyperalgesia. Prog Brain Res 110, 233-259.