Gabapentin and the neurokinin1 receptor antagonist CI-1021 act synergistically in two rat models of neuropathic pain

Journal of Pharmacology and Experimental Therapeutics

Volumn 303, Issue 2, 2002, Pages 730-735

  Field, Mark J ^a,b   Isabel Gonzalez, M ^c   Tallarida, Ronald J ^d   Singh, Lakhbir ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^d NONE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 (1H INDOL 3 YLMETHYL) 1 METHYL 2 OXO 2 [(1 PHENYLETHYL)AMINO]ETHYL 2 BENZOFURANYLMETHYL ESTER; 3 (2 METHOXYBENZYLAMINO) 2 PHENYLPIPERIDINE; [1 (1H INDOL 3 YLMETHYL) 1 METHYL 2 OXO 2 [(1 PHENYLETHYL)AMINO]ETHYL]CARBAMIC ACID BENZO[B]FURAN 2 YLMETHYL ESTER; GABAPENTIN; NEUROKININ 1 RECEPTOR ANTAGONIST; STREPTOZOCIN; UNCLASSIFIED DRUG;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; MALE; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; RAT;

ACETIC ACIDS; AMINES; ANIMALS; BENZOFURANS; CARBAMATES; CYCLOHEXANECARBOXYLIC ACIDS; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; EXCITATORY AMINO ACID ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; MALE; PAIN; PAIN MEASUREMENT; PERIPHERAL NERVOUS SYSTEM DISEASES; PIPERIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROKININ-1;

EID: 0036827574     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.033134     Document Type: Article

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