A painful peripheral neuropathy in the rat produced by the chemotherapeutic drug, paclitaxel

Pain

Volumn 94, Issue 3, 2001, Pages 293-304

  Polomano, Rosemary C ^a   Mannes, Andrew J ^b   Clark, Uraina S ^c   Bennett, Gary J ^c  

^a PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Allodynia; Chemotherapy neurotoxicity; Hyperalgesia; Neuropathy; Paclitaxel; Painful neuropathy; Taxanes; Taxol

Indexed keywords

PACLITAXEL;

ALLODYNIA; ANIMAL BEHAVIOR; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DORSAL ROOT; DOSE RESPONSE; ELECTRON MICROSCOPY; GRAY MATTER; HYPERALGESIA; MALE; MECHANICAL STIMULATION; MOTOR COORDINATION; MOTOR PERFORMANCE; NERVE FIBER DEGENERATION; NONHUMAN; PAIN; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SPINAL GANGLION; THERMAL STIMULATION; VENTRAL ROOT; WHITE MATTER;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BEHAVIOR, ANIMAL; COLD; DISEASE MODELS, ANIMAL; HEAT; HINDLIMB; HYPERALGESIA; MALE; MOTOR ACTIVITY; PACLITAXEL; PERIPHERAL NERVOUS SYSTEM DISEASES; PHYSICAL STIMULATION; RATS; RATS, SPRAGUE-DAWLEY; TAIL;

EID: 0035214661     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(01)00363-3     Document Type: Article

References (77)

1. Paclitaxel in advanced non-small cell lung cancer: An alternative to high-dose weekly schedule
2. Vincristine hyperalgesia in the rat: A model of painful vincristine neuropathy in humans
3. Nerve growth factor prevents toxic neuropathy in mice
4. Pain induced behaviour during vincristine-induced neuropathy in rats
5. Description of a short-term taxol-induced nociceptive neuropathy in rats
6. Reply to Hirata and his colleagues
7. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man
8. Progression of paclitaxel-induced neuropathy following discontinuation of treatment
9. Amelioration of experimental cisplatin and paclitaxel neuropathy with glutamate
10. A phase I trial of taxol given by a 6-hour intravenous infusion
11. Relationship between the structure of taxol and other taxanes on induction of tumor necrosis factor-alpha gene expression and cytotoxicity
12. Heat shock protein 90 mediates macrophage activation by taxol and bacterial polysaccharide
13. Prosaptide prevents paclitaxel neurotoxicity
14. Peripheral neurotoxicity of taxol in patients previously treated with cisplatin
15. Experimental peripheral neuropathy induced in adult rats by repeated intraperitoneal administration of taxol
16. Effect on the peripheral nervous system of the short-term intravenous administration of paclitaxel in the rat
17. Distribution of paclitaxel within the nervous system of the rat after repeated intravenous administration
18. Peripheral neuropathy from taxol and cisplatin combination chemotherapy: Clinical and electrophysiological studies
19. Behavioral signs of ongoing pain and cold allodynia in a rat model of neuropathic pain
20. Physiological characterization of taxol-induced large-fiber sensory neuropathy in the rat
21. Paclitaxel delivered as a 3-hr infusion with cisplatin in patients with gynecologic cancers: Unexpected incidence of neurotoxicity
22. Taxol induces the assembly of free microtubules in living cells and blocks the organizing capacity of centrosomes and kinetochores
23. Shared actions of endotoxin and taxol on TNF receptors and TNF release
24. Neuropathic pain from an experimental neuritis of the rat sciatic nerve
25. Possible mechanisms of paclitaxel-induced apoptosis
26. Prospective study of paclitaxel-induced peripheral neuropathy with quantitative sensory testing
27. Paclitaxel (taxol) induces cumulative mild neurotoxicity
28. Phase I dose escalation of paclitaxel in patients with advanced ovarian cancer receiving cisplatin: Rapid development of neurotoxicity is dose-limiting
29. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
30. Treatment with paclitaxel 1-h infusion and carboplatin of patients with advanced non-small-cell lung cancer: A phase II multicentre trial
31. Chemotherapy-induced peripheral neuropathy
32. Taxol counteracts colchicine's blockade of axonal transport in neuritis of cultured dorsal root ganglion cells
33. Effect of local methylprednisolone on pain in a nerve injury model. A pilot study
34. The quantitative mesurement of motor inco-ordination in naïve mice using an accelerating rotarod
35. Taxol causes permanent large fiber peripheral nerve dysfunction: A lesson for preventative strategies
36. Cold exposure enhances tactile allodynia transiently in mononeuropathic rats
37. Changes of fast axonal transport by taxol injected subepineurially into the rat sciatic nerve
38. Effects of taxol on slow and fast axonal transport
39. Paclitaxel by 1-h infusion in combination with carboplatin in advanced non-small cell lung carcinoma (NSCLC)
40. Regression analysis for correlated data
41. Taxol produces a predominantly sensory neuropathy
42. Taxol increases steady-state levels of lipopolysaccharide-inducible genes and protein-tyrosine phosphorylation in murine macrophages
43. Effects of taxol on isolated rat hepatocyte metabolism
44. Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer
45. Taxol metabolism. Isolation and identification of three major metabolites of taxol in rat bile
46. A behavioral model for peripheral neuropathy produced in the rat's tail by inferior caudal trunk injury
47. Effects of intraneural injection of taxol on retrograde axonal transport and morphology of corresponding nerve cell bodies
48. Paclitaxel neurotoxicity: Clinical and neurophysiological study of 23 patients
49. Taxol binds to polymerized tubulin in vitro
50. Paclitaxel-induced painful peripheral neuropathy in rats
51. Microtubule-mitochondrial associations in regenerating axons after taxol intoxication
52. Effects of vincristine, maytansine, and cis-platinum on behavioral and electrophysiological indices of neurotoxicity in the rat
53. Paclitaxel (taxol)
54. Microtubule changes and cytotoxicity in leukemic cell lines treated with taxol
55. Phase I and pharmacologic study of paclitaxel and cisplatin with granulocyte colony-stimulating factor: Neuromuscular toxicity is dose limiting
56. Clinical toxicities encountered with paclitaxel (TAXOL®)
57. Taxol-induced neuropathy: Further ultrastructural studies of nerve fibre changes in situ
58. Taxol-induced neuropathy: Chronic effects of local injection
59. Lipopolysaccharide increases glucocorticoid receptor expression in murine macrophages
60. Taxol stabilizes microtubules in mouse fibroblast cells
61. Neuropathy associated with mitochondrial disorders
62. Extra-territorial pain in rats with a peripheral mononeuropathy: Mechano-hyperalgesia and mechano-allodynia in the territory of an uninjured nerve
63. Microtubule disorientation and axonal swelling in unmyelinated sensory axons during vincristine-induced painful neuropathy in rat
64. Damage to the cytoskeleton of large diameter sensory neurons and myelinated axons in vincristine-induced painful peripheral neuropathy in the rat
65. Experimental cisplatin neuronopathy in rats and the effect of retinoic acid administration
66. Taxol-induced neuropathy after nerve crush: Long-term effects on Schwann and endoneurial cells
67. Taxol-induced neuropathy after nerve crush: Long-term effects on regenerating axons
68. The acute response of Schwann cells to taxol after nerve crush
69. The acute effect of taxol upon regenerating axons after nerve crush
70. The long-term effects of a single injection of taxol upon peripheral nerve axons
71. The long-term cellular response to taxol in peripheral nerve: Schwann cell and endoneurial cell changes
72. Phase II trial of paclitaxel and cisplatin in women with advanced breast cancer: An active regimen with limiting neurotoxicity
73. Phase I trial of taxol given as a 24-hour infusion every 21 days: Responses observed in metastatic melanoma
74. Phase I clinical and pharmacokinetic study of taxol
75. Magnesium suppresses neuropathic pain responses in rats via a spinal site of action
76. Ethical guidelines for investigations of experimental pain in conscious animals