Pain and its persistence in herpes zoster

Pain

Volumn 67, Issue 2-3, 1996, Pages 241-251

  Dworkin, Robert H ^a,c   Portenoy, Russell K ^b  

^a Columbia Univ Coll of Phys and S ^*  (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c New York Presbyterian Hospital Columbia University Medical Center   (United States)

Author keywords

acute pain; chronic pain; herpes zoster; postherpetic neuralgia

Indexed keywords

CHRONIC PAIN; HERPES ZOSTER; HUMAN; PAIN PARAMETERS; POSTHERPETIC NEURALGIA; PRIORITY JOURNAL; REVIEW;

EID: 0030273494     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3959(96)03122-3     Document Type: Article

References (132)

1. Aisen, P.S. and Davis, K.L., Inflammatory mechanisms in Alzheimer's disease: implications for therapy, Am. J. Psychiatry, 151 (1994) 1105-1113.
2. Arvin, A.M., Cell-mediated immunity to varicella-zoster virus, J. Infect. Dis., 166 (Suppl. 1) (1992) S35-S41.
3. Arvin, A.M., Pollard, R.B., Rasmussen, L.E. and Merigan, T.C., Selective impairment of lymphocyte reactivity to varicella-zoster virus antigen among untreated patients with lymphoma, J. Infect. Dis., 137 (1978) 531-540.
4. Balfour, Jr., H.H., Varicella zoster virus infections in immunocompromised hosts: a review of the natural history and management, Am. J. Med., 85 (Suppl. 2A) (1988) 68-73.
5. Balfour, Jr., H.H., Kelly, J.M., Suarez, C.S., Heussner, R.C., Englund, J.A., Crane, D.D., McGuirt, P.V., Clemmer, A.F. and Aeppli, D.M., Acyclovir treatment of varicella in otherwise healthy children, J. Pediatr., 116 (1990) 633-639.
6. Bamford, J.A.C. and Boundy, C.A.P., The natural history of herpes zoster (shingles), Med. J. Aust., 13 (1968) 524-528.
7. Baron, R. and Saguer, M., Postherpetic neuralgia: are C-nociceptors involved in signalling and maintenance of tactile allodynia? Brain, 116 (1993) 1477-1496.
8. Baron, R. and Saguer, M., Mechanical allodynia in postherpetic neuralgia: evidence for central mechanisms depending on nociceptive C-fiber degeneration, Neurology, 45 (Suppl. 8) (1995) S63-S65.
9. Bean, B., Deamant, C. and Aeppli, D., Acute zoster: course, complications and treatment in the immunocompetent host. In: C.P.N. Watson (Ed.), Herpes Zoster and Postherpetic Neuralgia, Elsevier, Amsterdam, 1993, pp. 37-58.
10. Bennett, G.J., Hypotheses on the pathogenesis of herpes zoster-associated pain, Ann. Neurol., 35 (Suppl.) (1994) S38-S41.
11. Bergbom Engberg, I., Gröndahl, G.-B. and Thibom, K., Patients' experiences of herpes zoster and postherpetic neuralgia, J. Adv. Nurs., 21 (1995) 427-433.
12. Berger, R., Florent, G. and Just, M., Decrease of the lymphoproliferative response to varicella-zoster virus antigen in the aged, Infect. Immun., 32 (1981) 24-27.
13. Beutner, K.R., Friedman, D.J., Forszpaniak, C., Andersen, P.L. and Wood, M.J., Valaciclovir compared with acyclovir for improved therapy for herpes zoster in immunocompetent adults, Antimicrob. Agents Chemother., 39 (1995) 1546-1553.
14. Bhala, B.B., Ramamoorthy, C., Bowsher, D. and Yelnoorker, K.N., Shingles and postherpetic neuralgia, Clin. J. Pain, 4 (1988) 169-174.
15. Boon, R., Efficacy and safety of famciclovir in the treatment of HZ, Second International Conference on the Varicella-Zoster Virus, Paris, 1994.
16. Boon, R. and Griffin, D.R.G., Efficacy of famciclovir in the treatment of herpes zoster: reduction of pain associated with zoster, Neurology, 45 (Suppl. 8) (1995) S76-S77.
17. Bowsher, D., Acute herpes zoster and postherpetic neuralgia: effects of acyclovir and outcome of treatment with amitriptyline, Br. J. Gen. Pract., 42 (1992) 244-246.
18. Bowsher, D., Sensory change in postherpetic neuralgia. In: C.P.N. Watson (Ed.), Herpes Zoster and Postherpetic Neuralgia, Elsevier, Amsterdam, 1993, pp. 97-107.
19. Brown, G.R., Herpes zoster: correlation of age, sex, distribution, neuralgia, and associated disorders, South. Med. J., 69 (1976) 576-578.
20. Bruxelle, J., Prospective epidemiologic study of painful and neurologic sequelae induced by herpes zoster in patients treated early with oral acyclovir, Neurology 45 (Suppl. 8) (1995) S78-S79.
21. Burgoon, C.F., Burgoon, J.S. and Baldridge, G.D., The natural history of herpes zoster, J. Am. Med. Assoc., 164 (1957) 265-269.
22. Burke, B.L., Steele, R.W., Beard, O.W., Wood, J.S., Cain, T.D. and Marmer, D.J., Immune responses to varicella-zoster in the aged, Arch. Intern. Med., 142 (1982) 291-293.
23. Chapman, C.R., The emotional aspects of pain. In: C.R. Chapman and K.M. Foley (Eds.), Current and Emerging Issues in Cancer Pain: Research and Practice, Raven Press, New York, 1993, pp. 83-98.
24. Crooks, R.J., Jones, D.A. and Fiddian, A.P., Zoster-associated chronic pain: an overview of clinical trials with acyclovir, Scand. J. Infect. Dis., Suppl. 78 (1991) 62-68.
25. Cunningham, A.L. Clinical success in treating patients with famciclovir: optimism for the future. Res. Clin. Forums, 17 (1995) 45-53.
26. Dan, K., Higa, K., Tanaka, K. and Mori, R., Herpetic pain and cellular immunity. In: T. Yokota and R. Dubner (Eds.), Current Topics in Pain Research and Therapy, Excerpta Medica, Amsterdam, 1983, pp. 293-305.
27. Davies, L., Cossins, L., Bowsher, D. and Drummond, M., The cost of treatment for post-herpetic neuralgia in the UK, PharmacoEconomics, 6 (1994) 142-148.
28. Degreef, H. and the Famciclovir Herpes Zoster Clinical Study Group, Famciclovir, a new oral antiherpes drug: results of the first controlled clinical study demonstrating its efficacy and safety in the treatment of uncomplicated herpes zoster in immunocompetent patients, Int. J. Antimicrob. Agents, 4 (1994) 241-246.
29. De Moragas, J.M. and Kierland, R.R., The outcome of patients with herpes zoster, Am. Med. Assoc. Arch. Dermatol., 75 (1957) 193-196.
30. Donohue, J.G., Choo, P.W., Manson, J.E. and Platt, R., The incidence of herpes zoster, Arch. Intern. Med., 155 (1995) 1605-1609.
31. Drummond, M. and Backhouse, M., Assessing the economic benefits of antiherpes therapy, J. Med. Virol., Suppl. 1 (1993) 51-57.
32. Dworkin, R.H. Racial differences in herpes zoster and the age of varicella infection, J. Infect. Dis., 174 (1996) 239-240.
33. Dworkin, R.H. and Portenoy, R.K., Proposed classification of herpes zoster pain, Lancet, 343 (1994) 1648.
34. Dworkin, R.H., Hartstein, G., Rosner, H.L., Walther, R.R., Sweeney, E.W. and Brand, L., A high-risk method for studying psychosocial antecedents of chronic pain: the prospective investigation of herpes zoster, J. Abnorm. Psychol., 101 (1992) 200-205.
35. Dworkin, R.H., Boon, R.J. and Griffin, D.R.G., Covariates in herpes zoster and interpretation of clinical trial data, Antiviral Res., 26 (1995a) A344.
36. Dworkin, R.H., Cooper, E.M., Walther, R.R. and Sweeney, E.W., Predicting the development of postherpetic neuralgia in acute herpes zoster patients: a diathesis-stress model, American Pain Society, Los Angeles, CA, 1995b.
37. Dworkin, R.H., Carrington, D., Cunningham, A., Kost, R., Levin, M., McKendrick, M., Oxman, M., Rentier, B., Schmader, K.E., Tappeiner, G., Wassilew, S.W. and Whitney, R.J., Assessment of pain in herpes zoster: lessons learned from antiviral trials, Antiviral Res., (1996) in press.
38. Esmann, V., Geil, J.P., Kroon, S., Fogh, H., Peterslund, N.A., Petersen, C.S., Rønne-Rasmussen, J.O. and Danielsen, L., Prednisolone does not prevent post-herpetic neuralgia, Lancet, 2 (1987) 126-129.
39. Fernandez, E. and Turk, D.C., Sensory and affective components of pain: separation and synthesis, Psychol. Bull., 112 (1992) 205-217.
40. Fiddian, A.P. and the International Zoster Study Group, A randomized, controlled trial of Zovirax (acyclovir, ACV) versus netivudine for the treatment of herpes zoster, Antiviral Res., 26 (1995) A297.
41. Fromm, G.H., Facial pain with herpes zoster and postherpetic neuralgia and a comparison with trigeminal neuralgia. In: C.P.N. Watson (Ed.), Herpes Zoster and Postherpetic Neuralgia, Elsevier, Amsterdam, 1993, pp. 109-122.
42. Garnett, G.P. and Grenfell, B.T., The epidemiology of varicella-zoster virus infections: the influence of varicella on the prevalence of herpes zoster, Epidemiol. Infect., 108 (1992) 513-528.
43. Gershon, A.A., Zoster in immunosuppressed patients. In: C.P.N. Watson (Ed.), Herpes Zoster and Postherpetic Neuralgia, Elsevier, Amsterdam, 1993, pp. 73-86.
44. Gilden, D.H., Herpes zoster with postherpetic neuralgia: persisting pain and frustration, N. Engl. J. Med., 330 (1994) 932-934.
45. Gilden, D.H., Dueland, A.N., Cohrs, R., Martin, J.R., Kleinschmidt-DeMasters, B.K. and Mahalingam, R., Preherpetic neuralgia, Neurology, 41 (1991) 1215-1218.
46. Gilden, D.H., Dueland, A.N., Devlin, M.E., Mahalingam, R. and Cohrs, R., Varicella-zoster virus reactivation without rash, J. Infect. Dis., 166 (Suppl. 1) (1992) S30-S34.
47. Gilden, D.H., Wright, R.R., Schneck, S.A., Gwaltney, J.M. and Mahalingam, R., Zoster sine herpete, a clinical variant, Ann. Neurol., 35 (1994) 530-533.
48. Glaser, R. and Kiecolt-Glaser, J.K., Stress-associated immune modulation and its implications for reactivation of latent herpesviruses. In: R. Glaser and J.F. Jones (Eds.), Herpesvirus Infections, Marcel Dekker, New York, 1994, pp. 245-270.
49. Gracely, R.H., Subjective quantification of pain perception. In: B. Bromm (Ed.), Pain Measurement in Man: Neurophysiological Correlates of Pain, Elsevier, Amsterdam, 1984, pp. 371-387.
50. Graff-Radford, S.B., Kames, L.D. and Naliboff, B.D., Measures of psychological adjustment and perception of pain in postherpetic neuralgia and trigeminal neuralgia, Clin. J. Pain, 2 (1986) 55-58.
51. Guess, H.A., Broughton, D.D., Melton, III, L.J. and Kurland, L.T., Epidemiology of herpes zoster in children and adolescents: a population-based study, Pediatrics, 76 (1985) 512-517.
52. Harding, S.P., Lipton, J.R. and Wells, J.C.D., Natural history of herpes zoster ophthalmicus: predictors of postherpetic neuralgia and ocular involvement, Br. J. Opthalmol., 71 (1987) 353-358.
53. Hardy, I., Gershon, A.A., Steinberg, S.P., LaRussa, P. and the Vari̊cella Vaccine Collaborative Study Group, The incidence of zoster after immunization with live attenuated varicella vaccine: a study of children with leukemia, N. Engl. J. Med., 325 (1991) 1545-1550.
54. Hayward, A.R. and Herberger, M., Lymphocyte responses to varicella zoster virus in the elderly, J. Clin. Immunol., 7 (1987) 174-178.
55. Hayward, A., Levin, M., Wolf, W., Angelova, G. and Gilden, D., Varicella-zoster virus-specific immunity after herpes zoster, J. Infect. Dis., 163 (1991), 873-875.
56. Head, H. and Campbell, A.W., The pathology of herpes zoster and its bearing on sensory localization, Brain, 23 (1900) 353-523.
57. Higa, K., Dan, K., Manabe, H. and Noda, B., Factors influencing the duration of treatment of acute herpetic pain with sympathetic nerve block: importance of severity of herpes zoster assessed by the maximum antibody titers to varicella-zoster virus in otherwise healthy patients, Pain, 32 (1988) 147-157.
58. Higa, K., Noda, B., Manabe, H., Sato, S. and Dan, K., T-lymphocyte subsets in otherwise healthy patients with herpes zoster and relationships to the duration of acute herpetic pain, Pain, 51 (1992) 111-118.
59. Hope-Simpson, R.E., Studies on shingles: is the virus ordinary chicken pox virus? Lancet, ii (1954) 1299-1302.
60. Hope-Simpson, R.E., The nature of herpes zoster: a long-term study and a new hypothesis, Proc. R. Soc. Med., 58 (1965) 9-20.
61. Hope-Simpson, R.E., Herpes zoster in the elderly, Geriatrics, 22 (1967) 151-159.
62. Hope-Simpson, R.E., Postherpetic neuralgia, J. R. Coll. Gen. Pract., 25 (1975) 571-575.
63. Huff, J.C., Drucker, J.L., Clemmer, A., Laskin, O.L., Connor, J.D., Bryson, Y.J. and Balfour, Jr., H.H., Effect of oral acyclovir on pain resolution in herpes zoster: a reanalysis, J. Med. Virol., Suppl. 1 (1993) 93-96.
64. Johnson, R.W., The future of predictors, prevention, and therapy in postherapetic neuralgia, Neurology, 45 (Suppl. 8) (1995) S70-S72.
65. Leijon, G., Boivie, J., Roberg, M. and Forsberg, P., Sensory abnormalities accompanying herpes zoster and post-herpetic neuralgia. In: Abstracts, 7th World Congress on Pain, IASP Publications, Seattle, WA, 1993, pp. 184-185.
66. Levin, M.J., Murray, M., Rotbart, H.A., Zerbe, G.O., White, C.J. and Hayward, A.R., Immune response of elderly individuals to a live attenuated varicella vaccine, J. Infect. Dis., 166 (1992) 253-259.
67. Levin, M.J., Murray, M., Zerbe G.O., White, C.J. and Hayward, A.R., Immune responses of elderly persons 4 years after receiving a live attenuated varicella vaccine, J. Infect. Dis., 170 (1994) 522-526.
68. Lewis, G.W., Zoster sine herpete, Br. Med. J., 2 (1958) 418-421.
69. Loeser, J.D., Herpes zoster and postherpetic neuralgia. Pain, 25 (1986) 149-164.
70. Loeser, J.D., Herpes zoster and postherpetic neuralgia. In: J.J. Bonica (Ed.), The Management of Pain, 2nd edn., Lea & Febiger, Philadelphia, 1990, pp. 257-263.
71. Lydick, E., Epstein, R.S., Himmelberger, D. and White, C.J., Herpes zoster and quality of life: a self-limited disease with severe impact, Neurology, 45 (Suppl. 8) (1995) S52-S53.
72. Mahalingam, R., Wellish, M., Lederer, D., Forghani, B., Cohrs, R. and Gilden, D., Quantitation of latent varicella-zoster virus DNA in human trigeminal ganglia by polymerase chain reaction, J. Virol., 67 (1993) 2381-2384.
73. Mauskopf, J., Austin, R., Dix, L. and Berzon, R., The Nottingham Health Profile as a measure of quality of life in zoster patients: convergent and discriminant validity, Qual. Life Res., 3 (1994) 431-435.
74. Max, M.B., Schafer, S.C., Culnane, M., Smoller, B., Dubner, R. and Gracely, R.H., Amitriptyline, but not lorazepam, relieves postherpetic neuralgia, Neurology, 38 (1988) 1427-1432.
75. McKendrick, M.W., Care, C.D., Ogan, P. and Wood, M.J., A retrospective study of the epidemiology of zoster with particular reference to factors pertinent to the development of chronic pain, Second International Conference on the Varicella-Zoster Virus, Paris, 1994.
76. Melzack, R. and Casey, K.L., Sensory, motivational, and central control determinants of pain: a new conceptual model. In: D.R. Kenshalo (Ed.), The Skin Senses, Thomas, Springfield, IL, 1968, pp. 423-443.
77. Merskey, H. and Bogduk, N. (Eds.), Classification of Chronic Pain: Descriptions of Chronic Pain Syndromes and Definitions of Pain Terms, 2nd edn., IASP Press, Seattle, WA, 1994.
78. Miller, A.E., Selective decline in cellular immune response to varicella-zoster in the elderly, Neurology, 30 (1980) 582-587.
79. Mitchell, C.D., Gehrz, R.C. and Balfour, Jr., H.H., Varicella-zoster-specific immune responses in acute herpes zoster during a placebo-controlled trial of oral acyclovir therapy, Diagn. Microbiol. Infect. Dis., 5 (1986) 113-126.
80. Molin, L., Aspects of the natural history of herpes zoster, Acta Derm.-Venereol., 49 (1969) 569-583.
81. Monroe, S.M. and Simons, A.D., Diathesis-stress theories in the context of life stress research: implications for the depressive disorders, Psychol. Bull., 110 (1991) 406-425.
82. Nandy, K. and Nandy, L.K., Immunological and autoimmune phenomena in senile brain disease. In: A.B. Scheibel, A.F. Wechsler and M.A.B. Brazier (Eds.), The Biological Substrates of Alzheimer's Disease, Academic Press, New York, 1986, pp. 167-176.
83. Nathwani, D., MacDonald, T. and Davey, P., Cost-effectiveness of acyclovir for varicella infections in immunocompetent patients: a British perspective, Infect. Dis. Clin. Pract., 4 (1995) 138-145.
84. Noda, B., Dan, K, Manabe, H. and Higa, K Prognostic clinical signs in herpes zoster pain, Pain, Suppl. 4 (1987) S382.
85. Nurmikko, T., Sensory dysfunction in postherpetic neuralgia. In: J. Boivie, P. Hansson and U. Lindblom (Eds.), Touch, Temperature, and Pain in Health and Disease: Mechanisms and Assessments, IASP Press, Seattle, WA, 1994, pp. 133-141.
86. Nurmikko, T., Clinical features and pathophysiologic mechanisms of postherpetic neuralgia, Neurology, 45 (Suppl. 8) (1995) S54-S55.
87. Nurmikko, T.J. and Bowsher, D., Somatosensory findings in postherpetic neuralgia, J. Neurol. Neurosurg. Psychiatry, 53 (1990) 135-141.
88. Nurmikko, T.J., Rasanen, A. and Hakkinen, V., Clinical and neurophysiological observations on acute herpes zoster, Clin. J. Pain, 6 (1990) 284-290.
89. Oxman, M., Immunization to reduce the frequency and severity of herpes zoster and its complications, Neurology, 45 (Suppl. 8) (1995) S41-S46.
90. Peterslund, N.A., Seyer-Hansen, K., Ipsen, J., Esmann, V., Schonheyder, H. and Juhl, H., Acyclovir in herpes zoster, Lancet, 2 (1981) 827-830.
91. Pilowsky, I., Psychological aspects of post-herpetic neuralgia: some clinical observations, Br. J. Med. Psychol., 50 (1977) 283-288.
92. Portenoy, R.K., Duma, C. and Foley, K.M., Acute herpetic and postherpetic neuralgia: clinical review and current management, Ann. Neurol., 20 (1986) 651-664.
93. Price, D.D., Psychological and Neural Mechanisms of Pain, Raven Press, New York, 1988.
94. Raggozzino, M.W., Melton, III, L.J., Kurland, L.T., Chu, C.P. and Perry, H.O., Population-based study of herpes zoster and its sequelae, Medicine, 61 (1982) 310-316.
95. Riopelle, J.M., Naraghi, M. and Grush, KP., Chronic neuralgia incidence following local anesthetic therapy for herpes zoster, Arch. Dermatol., 120 (1984) 747-750.
96. Rogers, III, R.S. and Tindall, J.P., Geriatric herpes zoster, J. Am. Geriatr. Soc., 19 (1971) 495-504.
97. Rose, M.J., Klenerman, L., Atchison, L. and Slade, P.D., An application of the fear avoidance model to three chronic pain conditions, Behav. Res, Ther., 30 (1992) 359-365.
98. Rowbotham, M.C. and Fields, H.L., Post-herpetic neuralgia: the relation of pain complaint, sensory disturbance, and skin temperature, Pain, 39 (1989) 129-144.
99. Rowbotham, M.C., Reisner-Keller, L. and Fields, H.L., Both intravenous lidocaine and morphine reduce the pain of postherpetic neuralgia, Neurology, 41 (1991) 1024-1028.
100. Rowbotham, M.C., Davies, P.S. and Fields, H.S., Topical lidocaine gel relieves postherpetic neuralgia, Ann. Neurol., 37 (1995) 246-253.
101. Rusthoven, J.J., Ahlgren, P., Elhakim, T., Pinfold, P., Reid, J., Stewart, L. and Feld, R., Varicella-zoster infection in adult cancer patients: a population study, Arch. Intern. Med., 148 (1988) 1561-1566.
102. Satterthwaite, J.R., Postherpetic neuralgia. In: C.D. Tollison (Ed.), Handbook of Chronic Pain Management, Williams & Wilkins, Baltimore, MD, 1989, pp. 460-474.
103. Schmader, K., Management of herpes zoster in elderly patients, Infect. Dis. Clin. Pract., 4 (1995) 293-299.
104. Schmader, K., Studenski, S., Macmillan, J., Grufferman, S. and Cohen, H.J., Are stressful life events risk factors for herpes zoster? J. Am. Geriatr. Soc., 38 (1990) 1188-1194.
105. Schmader, K., George, L.K., Burchett, B.M., Pieper, C.F. and Hamilton, J.D., Racial differences in the occurrence of herpes zoster, J. Infect. Dis., 171 (1995) 701-704.
106. Smith, F.P., Pathological studies of spinal nerve ganglia in relation to intractable intercostal pain, Surg. Neurol., 19 (1978) 50-53.
107. Straus, S.E., Reinhold, W., Smith, H.A., Ruyechan, W.T., Henderson, D.K., Blaese, R.M. and Hay, J., Endonuclease analysis of viral DNA from varicella and subsequent zoster infections in the same patient, N. Engl. J. Med., 311 (1984) 1362-1364.
108. Surman, O.S., Flynn, T., Schooley, R.T., Baer, L., Parker, S., Hirsch, M.S. and Davis, G., A double-blind, placebo-controlled study of oral acyclovir in postherpetic neuralgia, Psychosomatics, 31 (1990) 287-292.
109. Tyring, S., Barbarash, R.A., Nahlik, J.E., Cunningham, A., Marley, J., Heng, M., Jones, T., Rea, T., Boon, R., Saltzman, R. and the Collaborative Famciclovir Herpes Zoster Study Group, Famciclovir for the treatment of acute herpes zoster; effects on acute disease and postherpetic neuralgia: a randomized, double-blind, placebo-controlled trial, Ann. Intern. Med., 123 (1995) 89-96.
110. Wall, P.D., An essay on the mechanisms which may contribute to the state of postherpetic neuralgia. In: C.P.N. Watson (Ed.), Herpes Zoster and Postherpetic Neuralgia, Elsevier, Amsterdam, 1993, pp. 123-138.
111. Watson, C.P.N. (Ed.), Herpes Zoster and Postherpetic Neuralgia, Elsevier, Amsterdam, 1993.
112. Watson, C.P.N. and Chipman, M., Suggestions for research and unanswered questions regarding postherpetic neuralgia. In: C.P.N. Watson (Ed.), Herpes Zoster and Postherpetic Neuralgia, Elsevier, Amsterdam, 1993, pp. 139-157.
113. Watson, C.P.N. and Deck, J.H., The neuropathology of herpes zoster with particular reference to postherpetic neuralgia and its pathogenesis. In: C.P.N. Watson (Ed.), Herpes Zoster and Postherpetic Neuralgia, Elsevier, Amsterdam, 1993, pp. 139-157.
114. Watson, P.N. and Evans, R.J., Postherpetic neuralgia: a review, Arch. Neurol., 43 (1986) 836-840.
115. Watson, C.P.N., Evans, R.J., Watt, V.R. and Birkett, N., Post-herpetic neuralgia: 208 cases, Pain, 35 (1988a) 289-297.
116. Watson, C.P.N., Morshead, C., Van der Kooy, D., Deck, J. and Evans, R.J., Post-herpetic neuralgia: post-mortem analysis of a case, Pain, 34 (1988b) 129-138.
117. Watson, C.P.N., Deck, J.H., Morshead, C., Van der Kooy, D. and Evans, R.J., Post-herpetic neuralgia: further post-mortem studies of cases with and without pain, Pain, 44 (1991a) 105-117.
118. Watson, C.P.N., Watt, V.R., Chipman, M., Birkett, N. and Evans, R.J., The prognosis of postherpetic neuralgia, Pain, 46 (1991b) 195-199.
119. Watson, C.P.N., Chipman, M., Reed, K., Evans, R.J. and Birkett, N., Amitriptyline versus maprotiline in postherpetic neuralgia: a randomized, double-blind, crossover trial, Pain, 48 (1992) 29-36.
120. Weksler, M.E., Immune senescence, Ann. Neurol., 35 (1994) S35-S37.
121. Weller, T.H., Varicella-zoster virus: history, perspectives, and evolving concerns, Neurology, 45 (Suppl. 8) (1995) S9-S10.
122. Weller, T.H., Witton, H.M. and Bell, E.J., The etiologic agents of varicella and herpes zoster: isolation, propagation, and cultural characteristics in vitro, J. Exp. Med., 108 (1958) 843-868.
123. White, C.J., Varicella vaccine reflux, Pediatrics, 89 (1992) 353.
124. White, C.J., Kuter, B.J., Hildebrand, C.S., Isganitis, K.L., Matthews, H., Miller, W.J., Provost, P.J., Ellis, R.W., Gerety, R.J. and Calandra, G.B., Varicella vaccine (VARIVAX) in healthy children and adolescents: results from clinical trials, 1987 to 1989, Pediatrics, 87 (1991) 604-610.
125. Whitley, R.J., Weiss, H., Gnann, J., Tyring, S., Wolf, J., Pollard, R., Mertz, G., Pappas, P., Laughlin, C., Sherrill, L., Schlupner, C., Soong, S.J. and the NIAID Collaborative Antiviral Study Group, The efficacy of steroids and acyclovir therapy of herpes zoster in the elderly, Antiviral Res., 26 (1995) A303.
126. Wildenhoff, K.E., Ipsen, J., Esmann, V., Ingemann-Jensen, J. and Poulsen, J.H., Treatment of herpes zoster with idoxuridine ointment, including a multivariate analysis of symptoms and signs, Scand. J. Infect. Dis., 11 (1979) 1-9.
127. Wildenhoff, K.E., Esmann, V., Ipsen, J., Harving, H., Peterslund, N.A. and Schønheyder, H., Treatment of trigeminal and thoracic zoster with idoxuridine, Scand. J. Infect. Dis., 13 (1981) 257-262.
128. Wilson, J.B., Thirty-one years of herpes zoster in a rural practice, Br. Med. J., 293 (1986) 1349-1351.
129. Wood, M.J., Herpes zoster and pain, Scand. J. Infect. Dis., Suppl. 78 (1991) 53-61.
130. Wood, M.J., Johnson, R.W., McKendrick, M.W., Taylor, J., Mandal, B.K and Crooks, J., A randomized trial of acyclovir for 7 days or 21 days with and without prednisolone for treatment of acute herpes zoster, N. Engl. J. Med., 330 (1994) 896-900.
131. Wood, M.J. and the Herpes Zoster Clinical Trial Consensus Group, For debate: how should zoster trials be conducted? J. Antimicrob. Chemother., 36 (1995) 1089-1101.
132. Wood, M.J., Kay, R., Dworkin, R.H., Soong, S.-J. and Whitley, R.J., Oral acyclovir accelerates pain resolution in herpes zoster: a meta-analysis of placebo-controlled trials, Clin. Infect. Dis., 22 (1996) 341-347.