Spinal cord substance P receptor immunoreactivity increases in both inflammatory and nerve injury models of persistent pain

Neuroscience

Volumn 70, Issue 1, 1996, Pages 201-209

  Abbadie, C ^a,c   Brown, J L ^a   Mantyh, P W ^b   Basbaum, A I ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c Department of Anatomy ^*

Author keywords

[No Author keywords available]

Indexed keywords

SUBSTANCE P RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; INFLAMMATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; SPINAL CORD INJURY;

ANIMAL; INFLAMMATION; MALE; MODELS, BIOLOGICAL; PAIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROKININ-1; SPINAL CORD; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

EID: 0029655582     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(95)00343-H     Document Type: Article

References (54)

1. Arvidsson U., Dado R. J., Riedl M., Lee J. H., Law P. Y., Loh H. H., Elde R. and Wessendorf M. W. (1995) Delta-opioid receptor immunoreactivity: distribution in brainstem and spinal cord, and relationship to biogenic amines and enkephalin. J. Neurosci. 15, 1215-1235.
2. Attal N., Chen V. L., Kayser V. and Guilbaud G. (1991) Behavioural evidence that systemic morphine may modulate a phasic pain-related behaviour in a rat model of peripheral mononeuropathy. Pain 47, 65-70.
3. Barbut D., Polak J. M. and Wall P. D. (1981) Substance P in spinal cord dorsal horn decreases following peripheral nerve injury. Brain Res. 205, 289-298.
4. Besson J. M. and Chaouch A. (1987) Peripheral and spinal mechanisms of nociception. Physiol. Rev. 67, 67-185.
5. Bleazard L., Hill R. G. and Morris R. (1994) The correlation between the distribution of the NK1 reception and the actions of tachykinin agonists in the dorsal horn of the rat indicates that substance P does not have a functional role on substantia gelatinosa (lamina II) neurons. J. Neurosci. 14, 7655-7664.
6. Brown J. L., Liu H., Maggio J. E., Vigna S. R., Mantyh P. W. and Basbaum A. I. (1995) Morphological characterization of substance P receptor-immunoreactive neurons in the rat spinal cord and trigeminal nucleus caudalis. J. comp. Neurol. 356, 327-344.
7. Calvino B., Villanueva L. and Le Bars D. (1987) Dorsal horn (convergent) neurones in the intact anaesthetized arthritic rat. I. Segmental excitatory influences. Pain 28, 81-98.
8. Cook A. J. Woolf C. J., Wall P. D. and McMahon S. B. (1987) Dynamic receptive field plasticity in rat spinal cord dorsal horn following C-primary afferent input. Nature 325, 151-153.
9. Cridland R. A. and Henry J. L. (1988) Intrathecal administration of substance P in the rat: spinal transection or morphine blocks the behavioural responses but not the facilitation of the tail flick reflex. Neurosci. Lett. 84, 203-208.
10. De Koninck Y. and Henry J. L. (1991) Substance P-mediated slow excitatory postsynaptic potential elicited in dorsal horn neurons in vivo by noxious stimulation. Proc. natn. Acad. Sci. U.S.A. 88, 1344-1348.
11. Donaldson L. F., Harmar A. J., McQueen D. S. and Seckl J. R. (1992) Increased expression of preprotachykinin, calcitonin gene-related peptide, but not vasoactive intestinal peptide messenger RNA in dorsal root ganglia during the development of adjuvant monoarthritis in the rat. Molec. Brain Res. 16, 143-149.
12. Dray A., Urban L. and Dickenson A. (1994) Pharmacology of chronic pain. Trends pharmac. Sci. 15, 190-197.
13. Dubner R. (1991) Neuronal plasticity and pain following peripheral tissue inflammation or nerve injury. In Proceedings of the VIth World Congress on Pain (eds Bond M. R., Charlton J. E. and Woolf C. J.), pp. 263-276. Elsevier Science, Amsterdam.
14. Dubner R. and Ruda M. A. (1992) Activity-dependent neuronal plasticity following tissue injury and inflammation. Trends Neurosci. 15, 96-103.
15. Duggan A. W., Hendry I. A., Morton C. R., Hutchison W. D. and Zhao Z. Q. (1998) Cutaneous stimuli releasing immunoreactive substance P in the dorsal horn of the cat. Brain Res. 451, 261-273.
16. Duggan A. W., Hope P. J., Jarrot B., Schaible H. G. and Fleetwood Walker S. M. (1990) Release, spread and persistence of immunoreactive neurokinin A in the dorsal horn of the cat following noxious cutaneous stimulation. Studies with antibody microprobes. Neuroscience 35, 195-202.
17. Frenk H., Bossut D. and Mayer D. J. (1988) Is substance P a primary afferent neurotransmitter for nociceptive input? III. Valproic acid and chlordiazepoxide decrease behaviors elicited by intrathecal injection of substance P and excitatory compounds. Brain Res. 455, 240-246.
18. Garrison C. J., Dougherty P. M. and Carlton S. M. (1993) Quantitative analysis of substance P and calcitonin gene-related peptide immunohistochemical staining in the dorsal horn of neuropathic MK-801-treated rats. Brain Res. 607, 205-214.
19. Hökfelt T., Zhang X. and Wiesenfeld-Hallin Z. (1994) Messenger plasticity in primary sensory neurons following axotomy and its functional implications. Trends Neurosci. 17, 22-30.
20. Hsu S., Raine L. and Fanger H. (1981) A comparative study of the antiperoxidase method and an avidin-biotin complex method for studying polypeptide hormones with radioimmunoassay antibodies. Am. J. clin. Path. 75, 734-738.
21. Hylden J. L. and Wilcox G. L. (1981) Intrathecal substance P elicits a caudally-directed biting and scratching behavior in mice. Brain Res. 217, 212-215.
22. Hylden J. L. K., Nahin R. L. and Dubner R. (1987) Altered responses of nociceptive cat lamina I spinal dorsal horn neurons after chronic sciatic neuroma formation. Brain Res. 411, 341-350.
23. Kuraishi Y., Hirota N., Sato Y., Hanashima N., Takagi H. and Satoh M. (1989) Stimulus specificity of peripherally evoked substance P release from the rabbit dorsal horn in situ. Neuroscience 30, 241-250.
24. Laird J. M. and Bennett G. J. (1993) An electrophysiological study of dorsal horn neurons in the spinal cord of rats with an experimental peripheral neuropathy. J. Neurophysiol. 69, 2072-2085.
25. Lembeck F., Donnerer J. and Colpaert F. C. (1981) Increase of substance P in primary afferent nerves during chronic pain. Neuropeptides 1, 175-180.
26. Liu H., Brown J. L., Jasmin L., Maggio J. E., Vigna S. R., Mantyh P. W. and Basbaum A. I. (1994) Synaptic relationship between sustance P and the substance P receptor: light and electron microscopic characterization of the mismatch between neuropeptides and their receptors. Proc. natn. Acad. Sci. U.S.A. 91, 1009-1013.
27. Mantyh C. R., Gates T., Zimmerman R. P., Kruger L., Maggio J. E., Vigna S. R., Basbaum A. I., Levine J. and Mantyh P. W. (1988) Alterations in the density of receptor binding sites for sensory neuropeptides in the spinal cord of arthritic rats. In The Arthritic Rat as a Model of Clinical Pain? (eds Besson J. M. and Guilbaud G.), pp. 139-152. Excerpta Medica, Amsterdam.
28. Mantyh P. W., Allen C. J., Ghilardi J. R., Rogers S., Mantyh C. R., Liu H., Basbaum A. I., Vigna S. R. and Maggio J. E. (1995) Visualization of rapid endocytosis of a G protein-coupled receptor in the CNS in vivo: substance P evoked internalization of the substance P receptor in the rat striatum. Proc. natn. Acad. Sci. U.S.A. 92, 2622-2626.
29. Mantyh P. W., Demaster E., Malhotra A., Ghilardi J. R., Rogers S., Mantyh C. R., Liu H., Basbaum A. I., Vigna S. R., Maggio J. E. and Simone D. (1995) Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation. Science 268, 1629-1632.
30. Mantyh P. W. and Hunt S. P. (1985) The autoradiographic localization of substance P receptors in the rat and bovine spinal cord and the rat and cat spinal trigeminal pars caudalis and the effect of neonatal capsaicin. Brain Res. 332, 315-324.
31. Marlier L., Poulat P., Rajaofetra N. and Privat A. (1991) Modifications of serotonin-, substance P- and calcitonin gene-related peptide-like immunoreactivities in the dorsal horn of the spinal cord of arthritic rats: a quantative immunocytochemical study. Expl Brain Res. 85, 482-490.
32. McCarson K. E. and Goldstein B. D. (1991) Release of substance P into the superficial dorsal horn following nociceptive activation of the hindpaw of the rat. Brain Res. 568, 109-115.
33. McCarson K. E. and Krause J. E. (1994) NK-1 and NK-3 type tachykinin receptor mRNA expression in the rat spinal cord dorsal horn is increasing during adjuvant or formalin-induced nociception. J. Neurosci. 14, 712-720.
34. Menétrey D. and Besson J. M. (1982) Electrophysiological characteristics of dorsal horn cells in rats with cutaneous inflammation resulting from chronic arthritis. Pain 13, 343-364.
35. Molander C., Xu Q. and Grant G. (1984) The cytoarchitectonic organization of the spinal cord in the rat: I. The lower thoracic and lumbosacral cord. J. comp. Neurol. 230, 133-141.
36. 1 receptor: characterization and localization in the spinal cord. NeuroReport 3, 1073-1076.
37. Nakaya Y., Kaneko T., Shigemoto R., Nakanishi S. and Mizuno N. (1994) Immunohistochemical localization of substance P receptor in the central nervous system of the adult rat. J. comp. Neurol. 347, 249-274.
38. Noguchi K., Senba E., Mortia Y., Sato M. and Tohyama M. (1989) Prepro-VIP and preprotachykinin mRNAs in the rat dorsal root ganglion cells following peripheral axotomy. Molec. Brain Res. 6, 327-330.
39. Palecek J., Dougherty P. M., Kim S. H., Palecková V., Lekan H., Chung J. M., Carlton S. M. and Willis W. D. (1992) Responses of spinothalamic tract neurons to mechanical and thermal stimuli in an experimental model of peripheral neuropathy in primates. J. Neurophysiol. 68, 1951-1966.
40. Ren K., Hylden J., Williams G. M., Ruda M. A. and Dubner R. (1992) The effects of a non-competitive NMDA receptor antagonist, MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation. Pain 50, 331-344.
41. Schäfer M. K., Nohr D., Krause J. E. and Weihe E. (1993) Inflammation-induced upregulation of NK1 receptor mRNA in dorsal horn neurons. NeuroReport 4, 1007-1010.
42. Shults C. W., Quirion R., Chronwall B., Chase T. N. and O'Donohue T. L. (1984) A comparison of the anatomical distribution of substance P and substance P receptors in the rat central nervous system. Peptides 5, 1097-1128.
43. Smith G. D., Harmar A. J., McQueen D. S. and Seckl J. R. (1992) Increase in substance P and CGRP, but not somatostatin content of innervating dorsal root ganglia in adjuvant monoarthritis in the rat. Neurosci. Lett. 137, 257-260.
44. 125I-substance P binding in rat spinal cord following unilateral adjuvant-induced peripheral inflammation. Neuroscience 57, 397-409.
45. Swett J. E. and Woolf C. J. (1985) The somatotopic organization of primary afferent terminals in the superficial laminae of the dorsal horn of the rat spinal cord. J. comp. Neurol. 231, 66-77.
46. Vigna S. R., Bowden J. J., McDonald D. M., Fisher J., Okamoto A., McVey D. C., Payan D. G. and Bunnett N. W. (1994) Characterization of antibodies to the rat substance P (NK-1) receptor and to a chimeric substance P receptor expressed in mammalian cells. J. Neurosci. 14, 834-845.
47. Wall P. D. and Gutnick M. (1974) Properties of afferent nerve impulses orginating from a neuroma. Nature 248, 740-743.
48. Woolf C. J. (1987) Central terminations of cutaneous mechanoreceptive afferents in the rat lumbar spinal cord. J. comp. Neurol. 261, 105-119.
49. Woolf C. J. and Thompson S. (1991) The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states. Pain 44, 293-299.
50. Wright D. M. and Roberts M. H. T. (1978) Supersensitivity to a substance P analogue following dorsal root section. Life Sci. 22, 19-24.
51. Yaksh T. L., Jessell T. M., Gamse R., Mudge A. W. and Leeman S. E. (1980) Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo. Nature 286, 155-157.
52. Yamamoto T. and Yaksh T. L. (1991) Spinal pharmacology of thermal hyperesthesia induced by incomplete ligation of sciatic nerve: I. Opioid and nonopioid receptors. Anesthesiology 75, 817-826.
53. Yamamoto T. and Yaksh T. L. (1991) Stereospecific effects of a non-peptide NK-1 selective antagonist CP-96,345: antinociception in the absence of motor dysfunction. Life Sci. 49, 1955-1963.
54. Yashpal K., Dam T. V. and Quirion R. (1991) Effects of dorsal rhizotomy on neurokinin receptor sub-types in the rat spinal cord: a quantitative autoradiographic study. Brain Res. 552, 240-247.