Role of primary afferent nerves in allodynia caused by diabetic neuropathy in rats

Neuroscience

Volumn 114, Issue 2, 2002, Pages 291-299

  Khan, G M ^a   Chen, S R ^a   Pan, H L ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Diabetic neuropathy; Ectopic activity; Hypersensitivity; Myelinated afferents; Nociceptors; Resinoferatoxin

Indexed keywords

CAPSAICIN; RESINIFERATOXIN; STREPTOZOCIN;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEUROPATHY; ELECTROPHYSIOLOGY; HYPERALGESIA; MALE; MECHANICAL STIMULATION; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORY NERVE; SENSORY STIMULATION; TIBIAL NERVE;

AFFERENT PATHWAYS; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; DISEASE MODELS, ANIMAL; DITERPENES; GANGLIA, SPINAL; HYPERALGESIA; MALE; MICROSCOPY, ELECTRON; NERVE FIBERS, MYELINATED; NERVE FIBERS, UNMYELINATED; NEURONS, AFFERENT; NOCICEPTORS; PAIN THRESHOLD; PHYSICAL STIMULATION; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; TIBIAL NERVE;

EID: 0036774152     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(02)00372-X     Document Type: Article

References (33)

1. Ahlgren S.C., White D.M., Levine J.D. Increased responsiveness of sensory neurons in the saphenous nerve of the streptozotocin-diabetic rat. J. Neurophysiol. 68:1992;2077-2085.
2. Archer A.G., Watkins P.J., Thomas P.K., Sharma A.K., Payan J. The natural history of acute painful neuropathy in diabetes mellitus. J. Neurol. Neurosurg. Psychiatry. 46:1983;491-499.
3. Britland S.T., Young R.J., Sharma A.K., Clarke B.F. Association of painful and painless diabetic polyneuropathy with different patterns of nerve fiber degeneration and regeneration. Diabetes. 39:1990;898-908.
4. Brown M.J., Asbury A.K. Diabetic neuropathy. Ann. Neurol. 15:1984;2-12.
5. Burchiel K.J., Russell L.C., Lee R.P., Sima A.A. Spontaneous activity of primary afferent neurons in diabetic BB/Wistar rats. A possible mechanism of chronic diabetic neuropathic pain. Diabetes. 34:1985;1210-1213.
6. Campero M., Serra J., Marchettini P., Ochoa J.L. Ectopic impulse generation and autoexcitation in single myelinated afferent fibers in patients with peripheral neuropathy and positive sensory symptoms. Muscle Nerve. 21:1998;1661-1667.
7. Chaplan S.R., Bach F.W., Pogrel J.W., Chung J.M., Yaksh T.L. Quantitative assessment of tactile allodynia in the rat paw. J. Neurosci. Methods. 53:1994;55-63.
8. Chen J., Chen H.S. Pivotal role of capsaicin-sensitive primary afferents in development of both heat and mechanical hyperalgesia induced by intraplantar bee venom injection. Pain. 91:2001;367-376.
9. Chen S.R., Khan G.M., Pan H.L. Antiallodynic effect of intrathecal neostigmine is mediated by spinal nitric oxide in a rat model of diabetic neuropathic pain. Anesthesiology. 95:2001;1007-1012.
10. Chen S.R., Pan H.L. Spinal endogenous acetylcholine contributes to the analgesic effect of systemic morphine. Anesthesiology. 95:2001;525-530.
11. Chen S.R., Pan H.L. Hypersensitivity of spinothalamic tract neurons associated with diabetic neuropathic pain in rats. J. Neurophysiol. 87:2002;1938-1947.
12. Chen X., Levine J.D. Hyper-responsivity in a subset of C-fiber nociceptors in a model of painful diabetic neuropathy in the rat. Neuroscience. 102:2001;185-192.
13. Clark C.M. Jr., Lee D.A. Prevention and treatment of the complications of diabetes mellitus. N. Engl. J. Med. 332:1995;1210-1217.
14. Courteix C., Eschalier A., Lavarenne J. Streptozocin-induced diabetic rats: behavioural evidence for a model of chronic pain. Pain. 53:1993;81-88.
15. Gracely R.H., Lynch S.A., Bennett G.J. Painful neuropathy: altered central processing maintained dynamically by peripheral input. Pain. 51:1992;175-194.
16. Malcangio M., Fernandes K., Tomlinson D.R. NMDA receptor activation modulates evoked release of substance P from rat spinal cord. Br. J. Pharmacol. 125:1998;1625-1626.
17. Malcangio M., Tomlinson D.R. A pharmacologic analysis of mechanical hyperalgesia in streptozotocin/diabetic rats. Pain. 76:1998;151-157.
18. Matzner O., Devor M. Hyperexcitability at sites of nerve injury depends on voltage-sensitive Na+ channels. J. Neurophysiol. 72:1994;349-359.
19. Mizisin A.P., Shelton G.D., Wagner S., Rusbridge C., Powell H.C. Myelin splitting, Schwann cell injury and demyelination in feline diabetic neuropathy. Acta Neuropathol. (Berl.). 95:1998;171-174.
20. Ochodnicka E., Ochdnicky M., Belej K., Fusekova E., Bosel'ova L. Quantitative analysis of myelinated nerve fibers of peripheral nerve in streptozotocin-induced diabetes mellitus. Mol. Chem. Neuropathol. 25:1995;225-233.
21. Omana-Zapata I., Khabbaz M.A., Hunter J.C., Clarke D.E., Bley K.R. Tetrodotoxin inhibits neuropathic ectopic activity in neuromas, dorsal root ganglia and dorsal horn neurons. Pain. 72:1997;41-49.
22. Ossipov M.H., Bian D., Malan T.P. Jr., Lai J., Porreca F. Lack of involvement of capsaicin-sensitive primary afferents in nerve-ligation injury induced tactile allodynia in rats. Pain. 79:1999;127-133.
23. Pan H.L., Eisenach J.C., Chen S.R. Gabapentin suppresses ectopic nerve discharges and reverses allodynia in neuropathic rats. J. Pharmacol. Exp. Ther. 288:1999;1026-1030.
24. Pertovaara A., Wei H., Kalmari J., Ruotsalainen M. Pain behavior and response properties of spinal dorsal horn neurons following experimental diabetic neuropathy in the rat: modulation by nitecapone, a COMT inhibitor with antioxidant properties. Exp. Neurol. 167:2001;425-434.
25. Raz I., Hasdai D., Seltzer Z., Melmed R.N. Effect of hyperglycemia on pain perception and on efficacy of morphine analgesia in rats. Diabetes. 37:1988;1253-1259.
26. Szallasi A., Blumberg P.M. Vanilloid (Capsaicin) receptors and mechanisms. Pharmacol. Rev. 51:1999;159-212.
27. Szallasi A., Joo F., Blumberg P.M. Duration of desensitization and ultrastructural changes in dorsal root ganglia in rats treated with resiniferatoxin, an ultrapotent capsaicin analog. Brain Res. 503:1989;68-72.
28. Szallasi A., Szabo T., Biro T., Modarres S., Blumberg P.M., Krause J.E., Cortright D.N., Appendino G. Resiniferatoxin-type phorboid vanilloids display capsaicin-like selectivity at native vanilloid receptors on rat DRG neurons and at the cloned vanilloid receptor VR1. Br. J. Pharmacol. 128:1999;428-434.
29. Weis J., Dimpfel W., Schroder J.M. Nerve conduction changes and fine structural alterations of extra- and intrafusal muscle and nerve fibers in streptozotocin diabetic rats. Muscle Nerve. 18:1995;175-184.
30. Woolf, C.J., 1992. Excitability Changes in Central Neurons Following Peripheral Damage. In: Willis, W.D.J. (Ed.), Hyperalgesia and Allodynia. Raven, New York, pp. 221-243.
31. Woolf C.J., Shortland P., Coggeshall R.E. Peripheral nerve injury triggers central sprouting of myelinated afferents. Nature. 355:1992;75-78.
32. Wu G., Ringkamp M., Hartke T.V., Murinson B.B., Campbell J.N., Griffin J.W., Meyer R.A. Early onset of spontaneous activity in uninjured C-fiber nociceptors after injury to neighboring nerve fibers. J. Neurosci. 21:2001;RC140.
33. Yagihashi S., Kamijo M., Watanabe K. Reduced myelinated fiber size correlates with loss of axonal neurofilaments in peripheral nerve of chronically streptozotocin diabetic rats. Am. J. Pathol. 136:1990;1365-1373.