T cell receptor (TCR)-induced death of immature CD4+CD8+ thymocytes by two distinct mechanisms differing in their requirement for CD28 costimulation: Implications for negative selection in the thymus

Journal of Experimental Medicine

Volumn 186, Issue 11, 1997, Pages 1911-1922

  Punt, Jennifer A ^a,d   Havran, Wendy ^c   Abe, Ryo ^b,e   Sarin, Apurva ^a   Singer, Alfred ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NAVAL MEDICAL RESEARCH INSTITUTE   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d HAVERFORD COLLEGE   (United States)

^e TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; FEMALE; IMMUNOLOGICAL TOLERANCE; MOLECULAR CLONING; MOLECULAR MODEL; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE RECEPTOR GENE; THYMOCYTE;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, CD; ANTIGENS, CD28; ANTIGENS, CD80; ANTIGENS, CD95; APOPTOSIS; AUTOIMMUNITY; CLONAL DELETION; FAS LIGAND PROTEIN; FEMALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED MRL LPR; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MODELS, IMMUNOLOGICAL; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS; THYMUS GLAND; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030732750     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.186.11.1911     Document Type: Article

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