Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle

Journal of Cell Biology

Volumn 158, Issue 5, 2002, Pages 873-884

  Rogers, Stephen L ^a   Rogers, Gregory C ^b   Sharp, David J ^b   Vale, Ronald D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Dynamics; EB1; Microtubule; Mitosis; Spindle

Indexed keywords

CELL PROTEIN; EB1 PROTEIN; RNA; UNCLASSIFIED DRUG;

ANAPHASE; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL SPREADING; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DROSOPHILA; GENETIC CONSERVATION; IMMUNOFLUORESCENCE MICROSCOPY; INTERPHASE; METAPHASE; MICROINJECTION; MICROTUBULE ASSEMBLY; MITOSIS SPINDLE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROPHASE; PROTEIN LOCALIZATION; SPINDLE POLE BODY; TELOPHASE;

ANAPHASE; ANIMALS; CELL LINE; CHROMOSOME SEGREGATION; DROSOPHILA MELANOGASTER; INTERPHASE; MICROSCOPY, FLUORESCENCE; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MITOSIS; MITOTIC SPINDLE APPARATUS; TIME FACTORS;

ANIMALIA; METAZOA;

EID: 0037009077     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200202032     Document Type: Article

References (48)

1. Spindle assembly and the art of regulating microtubule dynamics by MAPs and Stathmin/Op 18
2. Mal3, the fission yeast homologue of the human APC-interacting protein EB-1 is required for microtubule integrity and the maintenance of cell form
3. The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain
4. It's a kar9ochore to capture microtubules
5. Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways
6. Microtubule polymerization dynamics
7. Kin I kinesins are microtubule-destabilizing enzymes
8. Origins of cell polarity
9. Dynein at the cortex
10. A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function
11. Mutations in the APC tumor suppressor gene cause chromosomal instability
12. Morphogenetic properties of microtubules and mitotic spindle assembly
13. EB/RP gene family encodes tubulin binding proteins
14. A role for the adenomatous polyposis coli protein in chromosome segregation
15. Organization of the cytoskeleton in early Drosophila embryos
16. Behavior of microtubules and actin filaments in living Drosophila embryos
17. Molecular linkage underlying microtubule orientation toward cortical sites in yeast
18. A class VI unconventional myosin is associated with a homologue of a microtubule-binding protein, cytoplasmic linker protein-170, in neurons and at the posterior pole of Drosophila embryos
19. Positioning of the mitotic spindle by a cortical-microtubule capture mechanism
20. Asymmetric cell division: Lessons from flies and worms
21. Adherens junctions inhibit asymmetric division in the Drosophila epithelium
22. Bim1p/Yeb1p mediates the Kar9p-dependent cortical attachment of cytoplasmic microtubules
23. Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells
24. The dynamic behavior of the APC-binding protein EB1 on the distal ends of microtubules
25. EB1, a protein which interacts with the APC tumor suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle
26. A cytokinesis checkpoint requiring the yeast homologue of an APC- binding protein
27. The adenomatous polyposis coli (APC) tumor suppressor
28. Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli
29. Cell cycle-dependent changes in microtubule dynamics in living cells expressing green fluorescent protein-α tubulin
30. Microtubule "plus-end-tracking proteins": The end is just the beginning
31. Control of spindle polarity and orientation in Saccharomyces cerevisiae
32. The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles
33. Functional coordination of three mitotic motors in Drosophila embryos
34. Microtubule motors in mitosis
35. Interzonal microtubules are dynamic during spindle elongation
36. Characterization of human MAPRE genes and their proteins
37. APC binds to the novel protein EB1
38. The cytoskeleton and morphogenesis of the early Drosophila embryo
39. Mutations affecting the cytoskeletal organization of syncytial Drosophila embryos
40. EB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stability
41. Yeast Bim1p promotes the G1-specific dynamics of microtubules
42. Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts
43. Drosophila melanogaster synctitial nuclear divisions are patterned: Time-lapse images, hypothesis and computational evidence
44. Dynamic instability of individual microtubules analyzed by video light microscopy: Rate constants and transition frequencies
45. Cell motility: Can Rho GTPases and microtubules lead the way?
46. Myosin V orientates the mitotic spindle in yeast
47. Taxol suppresses dynamics of individual microtubules in living human tumor cells
48. Microtubule dynamics at the G2/M transition: Abrupt breakdown of cytoplasmic microtubules at nuclear envelope breakdown and implications for spindle morphogenesis