A cytokinesis checkpoint requiring the yeast homologue of an APC-binding protein

Nature

Volumn 393, Issue 6684, 1998, Pages 487-491

  Muhua, Li ^a   Adames, Neil R ^a   Murphy, Michael D ^a   Shields, Colleen R ^a   Cooper, John A ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN;

ARTICLE; CONTROLLED STUDY; CYTOKINESIS; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; TUMOR SUPPRESSOR GENE;

1-PHOSPHATIDYLINOSITOL 4-KINASE; ADENOMATOUS POLYPOSIS COLI PROTEIN; CELL DIVISION; CYTOSKELETAL PROTEINS; FUNGAL PROTEINS; GENES, CDC; GENES, FUNGAL; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MITOTIC SPINDLE APPARATUS; MUTATION; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TEMPERATURE; VIDEOTAPE RECORDING;

EID: 0032482399     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/31014     Document Type: Article

References (19)

1. Yeh, E. ft al Spindle dynamics and cell cycle regulation of dynein in the budding yeast, Saccharomyces ccrevisiae. J. Cell Bioi 130,637-700 (1995).
2. Muhua, L, Karpova, T. S. & Cooper, J. A. A yeast actin-related protein homologous to that in vertebrate dynactin complex is important for spindle orientation and nuclear migration. Cell78,669-679(1994).
3. McMillan, J. N. & Tatchell, K. The /,YAf 1 gene in the yeast Saccharomyces cerevisiae is required for nuclear migration and spindle orientation during the mitotic cell cycle. J. Cell Bid 125, 143-158 (1994).
4. Yoshîda, S. et al. A novel gene, STT4, encodes a phosphaiidvlinosital 4-kinase in the PKCl protein kinase pathway of Saccharottiyces cerevisiae. J. Biol Chcm, 269, 1166-1172 (1994).
5. Su, L K. et ai APC binds to the novel protein EBI. Cancer Res. 55, 2972-2977 (1995).
6. Kinzler, K. W. & Vogelstein, B. Lessons from hereditary colorectal cancer. Off 87159-170 (1996).
7. Hartwell, L H. & Weinert, T. A. Checkpoints: controls that ensure the order of cell cycle events. Science 246,629-634(1989).
8. Elledge, S. J. Cell cycle checkpoints: preventing an identity crisis. Science 274,1664-1672 (1996).
9. Murray, A. W. The genetics of cell cycle checkpoints. Curr. Opin. Genet. Dev. 5, 5-11 (1995).
10. Munemitsu, S. et al The APC gene product associates with microtubules in vivo and promotes their assembly in vitro. Cancer Res. 54, 3676-3681 (1994).
11. Smith, K. J. et al Wild-type but not mutant APC associates with the microtubule cytoskeleton. Cancer Res. 54, 3672-3675 (1994).
12. Beinhaucr, J. D. et al Mal3, the fission yeast homologue of the human APC-interacting protein EB-1 is required for microtubule integrity and the maintenance of cell form. J. Cell Biol. 139,717-728 ( 1997).
13. Schwanz, K Richards, K. & Botstein, D. J.\f/ encodes a microtubule-binding protein in yeast. Mol Biol Cell 8, 2677-2691 (1997).
14. Sullivan, D. S. & Huffaker, T. C. Astral microtubules are not required for anaphase B in Saccharomyces cerevisiae. J. CcU Biol 119,379-388 (1992).
15. Li, Y. Y. et al Disruption of mitotic spindle orientation in a yeast dynein mutant Proc. KatlAcaJ. Set. USA 90, 10096-10100 (1993).
16. Dohmen, R. J., Wu, P. & Varshavsky, A. Heat-inducible degron: a method for constructing temperature sensitive mutants. Science 263, 1273-1276 ( 1994).
17. Straight, A. F. étal Mitosis in living budding yeast-anaphase A but no metaphase plate. Science 277, 574-578 (1997).
18. Waddle, J. A. et al Movement of cortical actin patches in yeast. J. Cell Biol 132, 861-870 (1996).
19. Weiss, E. & Wîney, M. The Saccharomyces cerevisiae spindle pole body duplication gene A/PS/ is part of a mitotic checkpoint. J. Cell Biol 132, 111-123 (1996).