SU11752 inhibits the DNA-dependent protein kinase and DNA double-strand break repair resulting in ionizing radiation sensitization

Oncogene

Volumn 23, Issue 4, 2004, Pages 873-882

  Ismail, Ismail Hassan ^a   Mårtensson, Susanne ^a   Moshinsky, Deborah ^b   Rice, Audie ^b   Tang, Cho ^b   Howlett, Anthony ^b   McMahon, Gerald ^b   Hammarsten, Ola ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b SUGEN INC   (United States)

Author keywords

ATM; DNA PK; Radiosensitizer; Radiotherapy

Indexed keywords

ADENOSINE TRIPHOSPHATE; ATM PROTEIN; DNA DEPENDENT PROTEIN KINASE; DNA DEPENDENT PROTEIN KINASE INHIBITOR; INDOLE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE INHIBITOR; SU 11752; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; CELL CYCLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA REPAIR; DNA STRAND; DNA STRAND BREAKAGE; ENZYME ACTIVITY; GLIOBLASTOMA; HUMAN; HUMAN CELL; INHIBITION KINETICS; IONIZING RADIATION; PRIORITY JOURNAL; RADIOSENSITIZATION;

ADENOSINE TRIPHOSPHATE; CELL CYCLE; DNA; DNA DAMAGE; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; ENZYME INHIBITORS; INDOLES; PROTEIN-SERINE-THREONINE KINASES; RADIATION, IONIZING;

EID: 1342343930     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207303     Document Type: Article

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