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Volumn 92, Issue 7, 1998, Pages 2213-2219

DNA-dependent protein kinase activity correlates with clinical and in vitro sensitivity of chronic lymphocytic leukemia lymphocytes to nitrogen mustards

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMBUCIL; CHLORMETHINE DERIVATIVE; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE;

EID: 0032189843     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.7.2213     Document Type: Article
Times cited : (86)

References (38)
  • 1
    • 0018102806 scopus 로고
    • Differences between melphalan and nitrogen mustard in the formation and removal of cross-links
    • Ross WE, Ewig RAG, Kohn KW: Differences between melphalan and nitrogen mustard in the formation and removal of cross-links. Cancer Res 38:1502, 1978
    • (1978) Cancer Res , vol.38 , pp. 1502
    • Ross, W.E.1    Ewig, R.A.G.2    Kohn, K.W.3
  • 2
    • 0019350535 scopus 로고
    • DNA crosslinking as an indicator of sensitivity and resistance of mouse L-1210 leukemia to cis-diamminedichloroplatinum (II) and L-phenylalanine nitrogen mustard
    • Zwelling LA, Michaels S, Schwartz H, Dobson PP, Kohn KW: DNA crosslinking as an indicator of sensitivity and resistance of mouse L-1210 leukemia to cis-diamminedichloroplatinum (II) and L-phenylalanine nitrogen mustard. Cancer Res 41:640, 1981
    • (1981) Cancer Res , vol.41 , pp. 640
    • Zwelling, L.A.1    Michaels, S.2    Schwartz, H.3    Dobson, P.P.4    Kohn, K.W.5
  • 3
    • 0023234707 scopus 로고
    • Formation and removal of crosslinks induced by melphalan and nitrogen mustard in relation to drug-induced cytotoxicity in human melanoma cells
    • Hansson JA, Lewensohn R, Ringborg U, Nilson B: Formation and removal of crosslinks induced by melphalan and nitrogen mustard in relation to drug-induced cytotoxicity in human melanoma cells. Cancer Res 47:2631, 1987
    • (1987) Cancer Res , vol.47 , pp. 2631
    • Hansson, J.A.1    Lewensohn, R.2    Ringborg, U.3    Nilson, B.4
  • 5
    • 0024470560 scopus 로고
    • Correlation of resistance to nitrogen mustards in chronic lymphocytic leukemia with enhanced removal of melphalan-induced DNA cross-links
    • Torres-Garcia SJ, Cousineau L, Caplan S, Panasci L: Correlation of resistance to nitrogen mustards in chronic lymphocytic leukemia with enhanced removal of melphalan-induced DNA cross-links. Biochem Pharmacol 38:3122, 1989
    • (1989) Biochem Pharmacol , vol.38 , pp. 3122
    • Torres-Garcia, S.J.1    Cousineau, L.2    Caplan, S.3    Panasci, L.4
  • 7
    • 0029892790 scopus 로고    scopus 로고
    • DNA excision repair
    • Sancar A: DNA excision repair. Annu Rev Biochem 65:43, 1996
    • (1996) Annu Rev Biochem , vol.65 , pp. 43
    • Sancar, A.1
  • 8
    • 0030580940 scopus 로고    scopus 로고
    • Evidence that mammalian cells possess homologous recombinational repair pathways
    • Thompson LH: Evidence that mammalian cells possess homologous recombinational repair pathways. Mutation Res 363:77, 1996
    • (1996) Mutation Res , vol.363 , pp. 77
    • Thompson, L.H.1
  • 9
    • 0029001136 scopus 로고
    • DNA repair enzyme expression in chronic lymphocytic leukemia vis-à-vis nitrogen mustard drug resistance
    • Bramson J, McQuillan A, Panasci LC: DNA repair enzyme expression in chronic lymphocytic leukemia vis-à-vis nitrogen mustard drug resistance. Cancer Lett 90:139, 1995
    • (1995) Cancer Lett , vol.90 , pp. 139
    • Bramson, J.1    McQuillan, A.2    Panasci, L.C.3
  • 10
    • 0029983352 scopus 로고    scopus 로고
    • DNA repair activity in protein extracts of fresh human malignant lymphoid cells
    • Barret JM, Calsou P, Laurent G, Salles B: DNA repair activity in protein extracts of fresh human malignant lymphoid cells. Mol Pharmacol 49:766, 1996
    • (1996) Mol Pharmacol , vol.49 , pp. 766
    • Barret, J.M.1    Calsou, P.2    Laurent, G.3    Salles, B.4
  • 11
    • 0030687578 scopus 로고    scopus 로고
    • Regulation of DNA-dependent protein kinase activity in leukemic cells
    • Muller C, Salles B: Regulation of DNA-dependent protein kinase activity in leukemic cells. Oncogene 15:2343, 1997
    • (1997) Oncogene , vol.15 , pp. 2343
    • Muller, C.1    Salles, B.2
  • 12
    • 0027468265 scopus 로고
    • Binding of Ku protein to DNA-Measurement of affinity for ends and demonstration of binding to nicks
    • Blier PR, Griffith AJ, Craft J, Hardin JA: Binding of Ku protein to DNA-Measurement of affinity for ends and demonstration of binding to nicks. J Biol Chem 268:7594, 1993
    • (1993) J Biol Chem , vol.268 , pp. 7594
    • Blier, P.R.1    Griffith, A.J.2    Craft, J.3    Hardin, J.A.4
  • 13
    • 0027156140 scopus 로고
    • EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single-to-double-strand transitions in DNA
    • Falzon M, Fewell JW, Kuff EL: EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single-to-double-strand transitions in DNA. J Biol Chem 268:10546, 1993
    • (1993) J Biol Chem , vol.268 , pp. 10546
    • Falzon, M.1    Fewell, J.W.2    Kuff, E.L.3
  • 14
    • 0023018810 scopus 로고
    • Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders
    • Minori T, Hardin JA: Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders. J Biol Chem 261:10375, 1986
    • (1986) J Biol Chem , vol.261 , pp. 10375
    • Minori, T.1    Hardin, J.A.2
  • 15
    • 0027397867 scopus 로고
    • The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
    • Gottlieb TM, Jackson SP: The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen. Cell 72:131, 1993
    • (1993) Cell , vol.72 , pp. 131
    • Gottlieb, T.M.1    Jackson, S.P.2
  • 16
    • 0025224761 scopus 로고
    • Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53 and the human Ku autoantigen
    • Lees-Miller SP, Chen YR, Anderson CW: Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53 and the human Ku autoantigen. Mol Cell Biol 10:6472, 1990
    • (1990) Mol Cell Biol , vol.10 , pp. 6472
    • Lees-Miller, S.P.1    Chen, Y.R.2    Anderson, C.W.3
  • 17
    • 0030900885 scopus 로고    scopus 로고
    • Functions of the DNA dependent protein kinase
    • Jin S, Inoue S, Weaver DT: Functions of the DNA dependent protein kinase. Cancer Surv 29:221, 1997
    • (1997) Cancer Surv , vol.29 , pp. 221
    • Jin, S.1    Inoue, S.2    Weaver, D.T.3
  • 18
    • 0028902932 scopus 로고
    • Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells
    • Peterson SR, Kurimasa A, Oshimura M, Dynan WS, Bradbury EM, Chen DJ: Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells. Proc Natl Acad Sci USA 92:3171, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3171
    • Peterson, S.R.1    Kurimasa, A.2    Oshimura, M.3    Dynan, W.S.4    Bradbury, E.M.5    Chen, D.J.6
  • 20
    • 0025734557 scopus 로고
    • Cross-sensitivity of gamma-ray-sensitive hamster mutants to cross-linking agents
    • Caldecott K, Jeggo P: Cross-sensitivity of gamma-ray-sensitive hamster mutants to cross-linking agents. Mutation Res 255:111, 1991
    • (1991) Mutation Res , vol.255 , pp. 111
    • Caldecott, K.1    Jeggo, P.2
  • 21
    • 0027279922 scopus 로고
    • The scid mutation in mice causes defects in the repair system for both double-strand DNA breaks and DNA cross-links
    • Tanaka T, Yamagami T, Oka Y, Nomura T, Sugiyama H: The scid mutation in mice causes defects in the repair system for both double-strand DNA breaks and DNA cross-links. Mutation Res 288:277, 1983
    • (1983) Mutation Res , vol.288 , pp. 277
    • Tanaka, T.1    Yamagami, T.2    Oka, Y.3    Nomura, T.4    Sugiyama, H.5
  • 22
    • 0019427092 scopus 로고
    • A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate analysis
    • Binet JL, Auquier A, Dighiero G: A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate analysis. Cancer 48:198, 1981
    • (1981) Cancer , vol.48 , pp. 198
    • Binet, J.L.1    Auquier, A.2    Dighiero, G.3
  • 23
    • 0023942406 scopus 로고
    • Transport, metabolism and DNA interaction of melphalan in lymphocytes from patients with chronic lymphocytic leukemia
    • Panasci L, Henderson D, Torres-Garcia SJ, Skalski V, Caplan S, Hutchinson M: Transport, metabolism and DNA interaction of melphalan in lymphocytes from patients with chronic lymphocytic leukemia. Cancer Res 48:1972, 1988
    • (1988) Cancer Res , vol.48 , pp. 1972
    • Panasci, L.1    Henderson, D.2    Torres-Garcia, S.J.3    Skalski, V.4    Caplan, S.5    Hutchinson, M.6
  • 25
    • 0028897304 scopus 로고
    • DNA-dependant kinase activity is absent in xrs6 cells: Implications for site specific recombination and DNA double strand break repair
    • Finnie NJ, Gottlieb TM, Blunt T, Jeggo PA, Jackson SP: DNA-dependant kinase activity is absent in xrs6 cells: Implications for site specific recombination and DNA double strand break repair. Proc Natl Acad Sci USA 92:320, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 320
    • Finnie, N.J.1    Gottlieb, T.M.2    Blunt, T.3    Jeggo, P.A.4    Jackson, S.P.5
  • 26
    • 0026687883 scopus 로고
    • Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53
    • Lees-Miller SP, Sakaguchi K, Ullrich S, Appella E, Anderson CW: Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53. Mol Cell Biol 12:11, 1992
    • (1992) Mol Cell Biol , vol.12 , pp. 11
    • Lees-Miller, S.P.1    Sakaguchi, K.2    Ullrich, S.3    Appella, E.4    Anderson, C.W.5
  • 28
    • 15844383710 scopus 로고    scopus 로고
    • Characterization of a Ku 86 variant protein that results in altered DNA-binding and diminished DNA-dependent protein kinase activity
    • Han Z, Johnston C, Reeves J, Carter T, Wyche JH, Hendrickson E: Characterization of a Ku 86 variant protein that results in altered DNA-binding and diminished DNA-dependent protein kinase activity. J Biol Chem 271:14098, 1996
    • (1996) J Biol Chem , vol.271 , pp. 14098
    • Han, Z.1    Johnston, C.2    Reeves, J.3    Carter, T.4    Wyche, J.H.5    Hendrickson, E.6
  • 29
    • 0027619421 scopus 로고
    • Murine monoclonal antibodies specific for conserved and non-conserved antigenic determinants of the human and murine Ku autoantigens
    • Wang J, Chou CH, Blankson J, Satoh M, Knuth MW, Eisenberg RA, Pisetsky DS, Reeves WH: Murine monoclonal antibodies specific for conserved and non-conserved antigenic determinants of the human and murine Ku autoantigens. Mol Biol Rep 18:15, 1993
    • (1993) Mol Biol Rep , vol.18 , pp. 15
    • Wang, J.1    Chou, C.H.2    Blankson, J.3    Satoh, M.4    Knuth, M.W.5    Eisenberg, R.A.6    Pisetsky, D.S.7    Reeves, W.H.8
  • 31
    • 0032568213 scopus 로고    scopus 로고
    • Human normal peripheral blood B lymphocytes are defective in DNA-dependent protein kinase activity due to the expression of a variant form of the Ku 86 protein
    • Muller C, Dusseau C, Calsou P, Salles B: Human normal peripheral blood B lymphocytes are defective in DNA-dependent protein kinase activity due to the expression of a variant form of the Ku 86 protein. Oncogene 16:1553, 1998
    • (1998) Oncogene , vol.16 , pp. 1553
    • Muller, C.1    Dusseau, C.2    Calsou, P.3    Salles, B.4
  • 32
    • 0029808695 scopus 로고    scopus 로고
    • The role of Ataxia Telangiectasia and the DNA-dependent protein kinase in the p53-mediated cellular response to ionizing radiation
    • Jongmans W, Artuso M, Vuillaume M, Brésil H, Jackson SP, Hall J: The role of Ataxia Telangiectasia and the DNA-dependent protein kinase in the p53-mediated cellular response to ionizing radiation. Oncogene 13:1133, 1996
    • (1996) Oncogene , vol.13 , pp. 1133
    • Jongmans, W.1    Artuso, M.2    Vuillaume, M.3    Brésil, H.4    Jackson, S.P.5    Hall, J.6
  • 33
    • 0026072331 scopus 로고
    • Expression of the Ku protein during cell proliferation
    • Yaneva M, Jhiang J: Expression of the Ku protein during cell proliferation. Biochim Biophys Acta 1090:181, 1991
    • (1991) Biochim Biophys Acta , vol.1090 , pp. 181
    • Yaneva, M.1    Jhiang, J.2
  • 34
    • 0028158320 scopus 로고
    • Chromosomal location and expression of the genes coding for Ku p70 and Ku p80 in human cell lines and normal tissues
    • Cai QQ, Plet AA, Imbert J, Lafagepochitaloff M, Cerdan C, Blanchard JM: Chromosomal location and expression of the genes coding for Ku p70 and Ku p80 in human cell lines and normal tissues. Cytogen Cell Genet 65:221, 1994
    • (1994) Cytogen Cell Genet , vol.65 , pp. 221
    • Cai, Q.Q.1    Plet, A.A.2    Imbert, J.3    Lafagepochitaloff, M.4    Cerdan, C.5    Blanchard, J.M.6
  • 35
    • 0028819412 scopus 로고
    • Role of free p70 (Ku) subunit in posttranslational stabilization of newly synthetised p80 during DNA dependent protein kinase assembly
    • Satoh M, Ajmani AK, Chou CH, Wang J, Reeves WH: Role of free p70 (Ku) subunit in posttranslational stabilization of newly synthetised p80 during DNA dependent protein kinase assembly. Eur J Cell Biol 66:127, 1995
    • (1995) Eur J Cell Biol , vol.66 , pp. 127
    • Satoh, M.1    Ajmani, A.K.2    Chou, C.H.3    Wang, J.4    Reeves, W.H.5
  • 36
    • 0020568235 scopus 로고
    • Chronic lymphocytic leukemia: A proliferative or a accumulative disorder?
    • Dörmer P, Thelm H, Lau B: Chronic lymphocytic leukemia: A proliferative or a accumulative disorder? Leuk Res 7:1, 1983
    • (1983) Leuk Res , vol.7 , pp. 1
    • Dörmer, P.1    Thelm, H.2    Lau, B.3
  • 37
    • 0023618535 scopus 로고
    • S phase lymphocytes in chronic lymphocytic leukemia (CLL) in relation to immunoglobulin isotypes on the leukemic clone and to disease activity
    • Kimby E, Mellstedt H, Nillson B, Tribukait B, Björkholm M, Holm G: S phase lymphocytes in chronic lymphocytic leukemia (CLL) in relation to immunoglobulin isotypes on the leukemic clone and to disease activity. Leukemia 1:432, 1987
    • (1987) Leukemia , vol.1 , pp. 432
    • Kimby, E.1    Mellstedt, H.2    Nillson, B.3    Tribukait, B.4    Björkholm, M.5    Holm, G.6
  • 38
    • 0032080433 scopus 로고    scopus 로고
    • Potentiation of chlorambucil cytotoxicity in B-cell chronic lymphocytic leukemia by inhibition of DNA-PK activity using wortmannin
    • Christodoulopoulos G, Muller C, Salles B, Kazmi R, Panasci L: Potentiation of chlorambucil cytotoxicity in B-cell chronic lymphocytic leukemia by inhibition of DNA-PK activity using wortmannin. Cancer Res 58:1789, 1998
    • (1998) Cancer Res , vol.58 , pp. 1789
    • Christodoulopoulos, G.1    Muller, C.2    Salles, B.3    Kazmi, R.4    Panasci, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.