Potentiation of chlorambucil cytotoxicity in B-cell chronic lymphocytic leukemia by inhibition of DNA-dependent protein kinase activity using wortmannin

Cancer Research

Volumn 58, Issue 9, 1998, Pages 1789-1792

  Christodoulopoulos, Garyfallia ^a   Muller, Catherine ^b   Salles, Bernard ^b   Kazmi, Rehan ^a   Panasci, Lawrence ^a  

^a MCGILL UNIVERSITY   (Canada)

^b INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; CHLORAMBUCIL; CHLORMETHINE; PROTEIN KINASE; WORTMANNIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CELL SURVIVAL; CHRONIC LYMPHATIC LEUKEMIA; CYTOTOXICITY; DNA ALKYLATION; DNA CROSS LINKING; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; HUMAN; HUMAN CELL; OUTCOMES RESEARCH; PRIORITY JOURNAL; SENSITIZATION; SEQUENCE HOMOLOGY;

ANDROSTADIENES; ANTINEOPLASTIC AGENTS, ALKYLATING; CELL SURVIVAL; CHLORAMBUCIL; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENZYME INHIBITORS; HUMANS; LEUKEMIA, B-CELL, CHRONIC; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; TUMOR CELLS, CULTURED;

EID: 0032080433     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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