Expression of 8-oxoguanine DNA glycosylase is reduced and associated with neurofibrillary tangles in Alzheimer's disease brain

Acta Neuropathologica

Volumn 103, Issue 1, 2002, Pages 20-25

  Iida, Takashi ^a,c   Furuta, Akiko ^a,c   Nishioka, Kenichi ^b   NAkabeppu, Yusaku ^b,c   Iwaki, Toru ^a,c  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

8 Oxo2 deoxyguanosine; 8 Oxoguanine DNA glycosylase (hOGGI); Alzheimer's disease; Immunohistochemistry; Oxidative DNA damage

Indexed keywords

8 HYDROXYGUANINE; DNA; DNA GLYCOSYLTRANSFERASE; MITOCHONDRIAL DNA; MONOCLONAL ANTIBODY; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; REACTIVE OXYGEN METABOLITE;

AGED; ALZHEIMER DISEASE; ARTICLE; ASTROCYTE; AUTOPSY; BRAIN TISSUE; CLINICAL ARTICLE; CLINICAL STUDY; CONTROLLED STUDY; CYTOPLASM; DISEASE ASSOCIATION; DNA DAMAGE; DNA REPAIR; ENTORHINAL CORTEX; ENZYME ANALYSIS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; MALE; MITOCHONDRION; NERVE CELL; NEURITE; NEUROFIBRILLARY TANGLE; ORBITAL CORTEX; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ANTIBODIES; BRAIN; DNA-FORMAMIDOPYRIMIDINE GLYCOSYLASE; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MITOCHONDRIA; N-GLYCOSYL HYDROLASES; NEUROFIBRILLARY TANGLES; OXIDATIVE STRESS;

EID: 0036942993     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010100418     Document Type: Article

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