Cyclooxygenase-2 expression is increased in early intestinal-type gastric cancer and gastric mucosa with intestinal metaplasia

European Journal of Gastroenterology and Hepatology

Volumn 14, Issue 4, 2002, Pages 359-363

  Yamagata, Ryo ^a   Shimoyama, Tadashi ^a   Fukuda, Shinsaku ^a   Yoshimura, Tetsuro ^a   Tanaka, Masanori ^a   Munakata, Akihiro ^a  

^a HIROSAKI UNIVERSITY   (Japan)

Author keywords

Cyclooxygenase 2; Gastric cancer; Helicobacter pylori; Intestinal metaplasia

Indexed keywords

CYCLOOXYGENASE 2; KI 67 ANTIGEN;

ADULT; ARTICLE; CANCER STAGING; CARCINOGENESIS; CLINICAL ARTICLE; CRYPT CELL; FEMALE; GENE OVEREXPRESSION; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINE METAPLASIA; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAINING; STOMACH CANCER; STOMACH MUCOSA;

CYCLOOXYGENASE 2; FEMALE; GASTRIC MUCOSA; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; ISOENZYMES; MALE; MEMBRANE PROTEINS; MIDDLE AGED; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; STOMACH NEOPLASMS;

EID: 0036229792     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-200204000-00004     Document Type: Article

References (34)

1. Expression of the protein product of the prostaglandin synthase-2/TIS10 gene in mitogen-stimulated Swiss 3T3 cells
2. Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues
3. TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
4. Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues: Effect of interleukin-1β, phorbol ester, and corticosteroids
5. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
6. Expression of cyclooxygenase-1 and -2 in human colorectal cancer
7. Aspirin use and risk of fatal cancer
8. A hypothesis: Nonsteroidal anti-inflammatory drugs reduce the incidence of large-bowel cancer
9. Aspirin use, cancer, and polyps of the large bowel
10. Reduced risk of large-bowel adenomas among aspirin users
11. Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis
12. Rectal proliferation and polyp occurrence in patients with familial adenomatous polyposis after sulindac treatment
13. Expression of cyclooxygenase-2 in human gastric carcinoma
14. Expression of cyclooxygenase-2 protein in gastric adenocarcinoma
15. Cyclooxygenase-2 expression in Helicobacter pylori-associated premalignant and malignant gastric lesions
16. Effects of NSAIDs on proliferation of gastric cancer cells in vitro: Possible implication of cyclooxygenase-2 in cancer development
17. Helicobacter pylori up-regulates cyclooxygenase-2 mRNA expression and prostaglandin E2 synthesis in MKN28 gastric mucosal cells in vitro
18. Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase-2 in Helicobacter pylori gastritis
19. Cyclooxygenase-2 expression in gastric antral mucosa before and after eradication of Helicobacter pylori infection
20. Expression of cyclooxygenase-2 in dysplasia of the stomach and in intestinal-type gastric adenocarcinoma
21. Cyclooxygenase-2 overexpression enhances lymphatic invasion and metastasis in human gastric cancer
22. The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma: An attempt at a histo-clinical classification
23. Japanese classification of gastric carcinoma - 2nd English edition
24. Overexpression of cyclooxygenase-2 protein is less frequent in gastric cancers with microsatellite instability
25. Localisation of cyclooxygenase 1 and cyclooxygenase 2 in Helicobacter pylori related gastritis and gastric ulcer tissues in humans
26. Carcinoma and intestinal metaplasia in the stomach of Colombian migrants
27. Analysis of cell damage and proliferation in Helicobacter pylori-infected human gastric mucosa from patients with gastric adenocarcinoma
28. Ki-67 and other proliferation markers useful for immunohistological diagnostic and prognostic evaluations in human malignancies
29. Cell proliferation in gastrointestinal mucosa
30. Cell proliferation in Helicobacter pylori associated gastritis and the effect of eradication therapy
31. Increased COX-2, but not COX-1, mRNA expression in Helicobacter pylori gastritis
32. Increase in proliferation and apoptosis of gastric epithelial cells early in the natural history of Helicobacter pylori infection
33. Nonsteroidal anti-inflammatory drugs could reverse Helicobacter pylori-induced apoptosis and proliferation in gastric epithelial cells