Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective non-steroidal anti-inflammatory agent in BAX-deficient cells

Oncogene

Volumn 21, Issue 39, 2002, Pages 6032-6040

  He, Qin ^a   Luo, Xiuquan ^a   Huang, Ying ^a   Sheikh, M Saeed ^a  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

Bax; Caspases; Colon cancer; Death receptor 5; NSAIDs; TRAIL Apo2L

Indexed keywords

4 [5 (4 CHLOROPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOL 1 YL]BENZENESULFONAMIDE; CASPASE 3; CASPASE 8; CASPASE 9; CYCLOOXYGENASE 2 INHIBITOR; CYTOCHROME C; NONSTEROID ANTIINFLAMMATORY AGENT; PROTEIN BAX; PROTEIN BID; SULINDAC; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; COLON CANCER; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME ACTIVATION; GENE MUTATION; HUMAN; HUMAN CELL; MITOCHONDRION; PRIORITY JOURNAL; RECEPTOR UPREGULATION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, NORTHERN; BLOTTING, WESTERN; CASPASES; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; CYTOCHROME C GROUP; ENZYME ACTIVATION; HT29 CELLS; HUMANS; ISOENZYMES; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRAZOLES; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR; RNA, MESSENGER; SULFONAMIDES; SULINDAC; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 0037026582     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1205897     Document Type: Article

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