Prognostic significance of elevated cyclooxygenase 2 expression in patients with adenocarcinoma of the esophagus

Gastroenterology

Volumn 122, Issue 7, 2002, Pages 1800-1807

  Buskens, Christianne J ^a   Van Rees, Bastiaan P ^d   Sivula, Anna ^a,b   Reitsma, Johannes B ^e   Haglund, Caj ^f   Bosma, Piter J ^a   Offerhaus, G Johan ^d   Van Lanschot, J Janb ^c   Ristimäki, Ari ^a,c  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UNIVERSITY OF HELSINKI   (Finland)

^c Departments of Pathology ^*

^d Departments of Pathology   (Finland)

^e Departments of Clinical Epidemiology and Biostatistics   (Finland)

^f HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; NONSTEROID ANTIINFLAMMATORY AGENT;

ADENOCARCINOMA; ADULT; AGED; ARTICLE; BARRETT ESOPHAGUS; ESOPHAGUS CARCINOMA; FEMALE; HISTOPATHOLOGY; HUMAN; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; SQUAMOUS EPITHELIUM; TARGET CELL; TISSUE SECTION; TUMOR RECURRENCE;

EID: 0036083347     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/gast.2002.33580     Document Type: Article

References (38)

1. Increasing incidence of adenocarcinoma of the esophagus and esophagogastric junction
2. Cancer statistics, 2001
3. Barrett’s esophagus
4. Aspirin, NSAIDs, and digestive tract cancers
5. The role of nonsteroidal anti-inflammatory drugs in colorectal cancer prevention
6. Cyclooxygenase-2 inhibitors in tumorigenesis (part II)
7. Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2
8. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
9. Cyclooxygenase-2 in carcinogenesis of the gastrointestinal tract
10. Expression of cyclooxygenase-2 in dysplasia of the stomach and in intestinal type gastric adenocarcinoma
11. Multivariable prognostic models: Issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors
12. Judging the causal role of a potential confounder
13. The recurrence pattern of esophageal carcinoma after transhiatal resection
14. Upregulation of cyclooxygenase-2 in squamous carcinogenesis of the esophagus
15. Cyclooxygenase-2 overexpression enhances lymphatic invasion and metastasis in human gastric carcinoma
16. Overexpression of cyclooxygenase-2 protein is less frequent in gastric cancers with microsatellite instability
17. Increased expression of cyclooxygenase-2 protein in human gastric carcinoma
18. Association between cyclo-oxygenase-2 overexpression and missense p53 mutations in gastric cancer
19. The relationship between cyclooxygenase-2 expression and colorectal cancer
20. Cyclooxygenase-2 expression correlates with tumor neovascularization and prognosis in human colorectal carcinoma patients
21. Cyclooxygenase-2 overexpression correlates with tumour recurrence, especially haematogenous metastasis, of colorectal cancer
22. Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in Barrett’s esophagus and associated adenocarcinomas
23. Cyclooxygenase 2 expression in Barrett’s esophagus and adenocarcinoma: Ex vivo induction by bile salts and acid exposure
24. Cyclooxygenase-2 expression in Barrett’s esophagus
25. Cyclooxygenase-2 expression in the Barrett’s metaplasia-dysplasiaadenocarcinoma sequence
26. Cyclooxygenase-2 expression during carcinogenesis in the human stomach
27. Aspirin use and risk of fatal cancer
28. Aspirin and reduced risk of esophageal carcinoma
29. Use of aspirin and other nonsteroidal anti-inflammatory drugs and risk of esophageal and gastric cancer
30. Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts
31. Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)
32. Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice
33. Over-expression of cyclooxygenase (Cox-2) is sufficient to induce tumorigenesis in transgenic mice
34. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
35. Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential
36. Cyclooxygenase regulates angiogenesis induced by colon cancer
37. Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells
38. Dihydroxy bile acids activate the transcription of cyclooxygenase-2