-
1
-
-
15844386165
-
Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome
-
Cambridge, Mass.
-
Hahn, H., Wicking, C., Zaphiropoulos, P. G., Gailani, M. R., Shanley, S., Chidambaram, A., Vorechovsky, I., Holmberg, E., Unden, A. B., Gillies, S. et al. (1996) Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell (Cambridge, Mass.) 85, 841-851
-
(1996)
Cell
, vol.85
, pp. 841-851
-
-
Hahn, H.1
Wicking, C.2
Zaphiropoulos, P.G.3
Gailani, M.R.4
Shanley, S.5
Chidambaram, A.6
Vorechovsky, I.7
Holmberg, E.8
Unden, A.B.9
Gillies, S.10
-
2
-
-
15844381336
-
Human homolog of patched, a candidate gene for the basal cell nevus syndrome
-
Johnson, R. L., Rothman, A. L., Xie, J., Goodrich, L. V., Bare, J. W., Bonifas, J. M., Quinn, A. G., Myers, R. M., Cox, D. R., Epstein, Jr, E. H. et al. (1996) Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 272, 1668-1671
-
(1996)
Science
, vol.272
, pp. 1668-1671
-
-
Johnson, R.L.1
Rothman, A.L.2
Xie, J.3
Goodrich, L.V.4
Bare, J.W.5
Bonifas, J.M.6
Quinn, A.G.7
Myers, R.M.8
Cox, D.R.9
Epstein Jr., E.H.10
-
3
-
-
0032474837
-
Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion
-
Bellaiche, Y., The, I. and Perrimon, N. (1998) Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion. Nature (London) 394, 85-88
-
(1998)
Nature (London)
, vol.394
, pp. 85-88
-
-
Bellaiche, Y.1
The, I.2
Perrimon, N.3
-
4
-
-
0033598964
-
Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells
-
Cambridge, Mass.
-
Burke, R., Nellen, D., Bellotto, M., Hafen, E., Senti, K. A., Dickson, B. J. and Basler, K. (1999) Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells. Cell (Cambridge, Mass.) 99, 803-815
-
(1999)
Cell
, vol.99
, pp. 803-815
-
-
Burke, R.1
Nellen, D.2
Bellotto, M.3
Hafen, E.4
Senti, K.A.5
Dickson, B.J.6
Basler, K.7
-
5
-
-
0029844192
-
Cholesterol modification of hedgehog signaling proteins in animal development
-
Porter, J. A., Young, K. E. and Beachy, P. A. (1996) Cholesterol modification of hedgehog signaling proteins in animal development. Science 274, 255-259
-
(1996)
Science
, vol.274
, pp. 255-259
-
-
Porter, J.A.1
Young, K.E.2
Beachy, P.A.3
-
6
-
-
15444359695
-
Identification of a palmitic acid-modified form of human Sonic hedgehog
-
Pepinsky, R. B., Zeng, C., Wen, D., Rayhorn, P., Baker, D. P., Williams, K. P., Bixler, S. A., Ambrose, C. M., Garber, E. A., Miatkowski, K. et al. (1998) Identification of a palmitic acid-modified form of human Sonic hedgehog. J. Biol. Chem. 273, 14037-14045
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14037-14045
-
-
Pepinsky, R.B.1
Zeng, C.2
Wen, D.3
Rayhorn, P.4
Baker, D.P.5
Williams, K.P.6
Bixler, S.A.7
Ambrose, C.M.8
Garber, E.A.9
Miatkowski, K.10
-
7
-
-
0035691773
-
Gli1 can rescue the in vivo function of Gli2
-
Bai, C. B. and Joyner, A. L. (2001) Gli1 can rescue the in vivo function of Gli2. Development 128, 5161-5172
-
(2001)
Development
, vol.128
, pp. 5161-5172
-
-
Bai, C.B.1
Joyner, A.L.2
-
8
-
-
0033580269
-
Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein
-
Chuang, P. T. and McMahon, A. P. (1999) Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein. Nature (London) 397, 617-621
-
(1999)
Nature (London)
, vol.397
, pp. 617-621
-
-
Chuang, P.T.1
McMahon, A.P.2
-
9
-
-
0037026603
-
Alternative first exons of PTCH1 are differentially regulated in vivo and may confer different functions to the PTCH1 protein
-
Kogerman, P., Krause, D., Rahnama, F., Kogerman, L., Unden, A. B., Zaphiropoulos, P. G. and Toftgard, R. (2002) Alternative first exons of PTCH1 are differentially regulated in vivo and may confer different functions to the PTCH1 protein. Oncogene 21, 6007-6016
-
(2002)
Oncogene
, vol.21
, pp. 6007-6016
-
-
Kogerman, P.1
Krause, D.2
Rahnama, F.3
Kogerman, L.4
Unden, A.B.5
Zaphiropoulos, P.G.6
Toftgard, R.7
-
10
-
-
0033636788
-
In vivo functions of the patched protein: Requirement of the C terminus for target gene inactivation but not Hedgehog sequestration
-
Johnson, R. L., Milenkovic, L. and Scott, M. P. (2000) In vivo functions of the patched protein: requirement of the C terminus for target gene inactivation but not Hedgehog sequestration. Mol. Cell 6, 467-478
-
(2000)
Mol. Cell
, vol.6
, pp. 467-478
-
-
Johnson, R.L.1
Milenkovic, L.2
Scott, M.P.3
-
11
-
-
0035846946
-
Post-transcriptional regulation of the gli1 oncogene by the expression of alternative 5′ untranslated regions
-
Wang, X. Q. and Rothnagel, J. A. (2001) Post-transcriptional regulation of the gli1 oncogene by the expression of alternative 5′ untranslated regions. J. Biol. Chem. 276, 1311-1316
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 1311-1316
-
-
Wang, X.Q.1
Rothnagel, J.A.2
-
12
-
-
0030863352
-
Niemann-Pick C1 disease gene: Homology to mediators of cholesterol homeostasis
-
Carstea, E. D., Morris, J. A., Coleman, K. G., Loftus, S. K., Zhang, D., Cummings, C., Gu, J., Rosenfeld, M. A., Pavan, W. J., Krizman, D. B. et al. (1997) Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis. Science 277, 228-231
-
(1997)
Science
, vol.277
, pp. 228-231
-
-
Carstea, E.D.1
Morris, J.A.2
Coleman, K.G.3
Loftus, S.K.4
Zhang, D.5
Cummings, C.6
Gu, J.7
Rosenfeld, M.A.8
Pavan, W.J.9
Krizman, D.B.10
-
13
-
-
0030768084
-
Murine model of Niemann-Pick C disease: Mutation in a cholesterol homeostasis gene
-
Loftus, S. K., Morris, J. A., Carstea, E. D., Gu, J. Z., Cummings, C., Brown, A., Ellison, J., Ohno, K., Rosenfeld, M. A., Tagle, D. A. et al. (1997) Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene. Science 277, 232-235
-
(1997)
Science
, vol.277
, pp. 232-235
-
-
Loftus, S.K.1
Morris, J.A.2
Carstea, E.D.3
Gu, J.Z.4
Cummings, C.5
Brown, A.6
Ellison, J.7
Ohno, K.8
Rosenfeld, M.A.9
Tagle, D.A.10
-
14
-
-
0035901616
-
The sterol-sensing domain of Patched protein seems to control Smoothened activity through Patched vesicular trafficking
-
Martin, V., Carrillo, G., Torroja, C. and Guerrero, I. (2001) The sterol-sensing domain of Patched protein seems to control Smoothened activity through Patched vesicular trafficking. Curr. Biol. 11, 601-607
-
(2001)
Curr. Biol.
, vol.11
, pp. 601-607
-
-
Martin, V.1
Carrillo, G.2
Torroja, C.3
Guerrero, I.4
-
15
-
-
0035901572
-
Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation
-
Strutt, H., Thomas, C., Nakano, Y., Stark, D., Neave, B., Taylor, A. M. and Ingham, P. W. (2001) Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation. Curr. Biol. 11, 608-613
-
(2001)
Curr. Biol.
, vol.11
, pp. 608-613
-
-
Strutt, H.1
Thomas, C.2
Nakano, Y.3
Stark, D.4
Neave, B.5
Taylor, A.M.6
Ingham, P.W.7
-
16
-
-
0037083492
-
Distinct consequences of sterol sensor mutations in Drosophila and mouse patched homologs
-
Johnson, R. L., Zhou, L. and Bailey, E. C. (2002) Distinct consequences of sterol sensor mutations in Drosophila and mouse patched homologs. Dev. Biol. 242, 224-235
-
(2002)
Dev. Biol.
, vol.242
, pp. 224-235
-
-
Johnson, R.L.1
Zhou, L.2
Bailey, E.C.3
-
17
-
-
0033557853
-
PTCH2, a novel human patched gene, undergoing alternative splicing and up-regulated in basal cell carcinomas
-
Zaphiropoulos, P. G., Unden, A. B., Rahnama, F., Hollingsworth, R. E. and Toftgard, R. (1999) PTCH2, a novel human patched gene, undergoing alternative splicing and up-regulated in basal cell carcinomas. Cancer Res. 59, 787-792
-
(1999)
Cancer Res.
, vol.59
, pp. 787-792
-
-
Zaphiropoulos, P.G.1
Unden, A.B.2
Rahnama, F.3
Hollingsworth, R.E.4
Toftgard, R.5
-
18
-
-
0030027059
-
Conservation of the hedgehog/patched signaling pathway from flies to mice: Induction of a mouse patched gene by Hedgehog
-
Goodrich, L. V., Johnson, R. L., Milenkovic, L., McMahon, J. A. and Scott, M. P. (1996) Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev. 10, 301-312
-
(1996)
Genes Dev.
, vol.10
, pp. 301-312
-
-
Goodrich, L.V.1
Johnson, R.L.2
Milenkovic, L.3
McMahon, J.A.4
Scott, M.P.5
-
19
-
-
0029975823
-
Conservation in hedgehog signaling: Induction of a chicken patched homolog by Sonic hedgehog in the developing limb
-
Marigo, V., Scott, M. P., Johnson, R. L., Goodrich, L. V. and Tabin, C. J. (1996) Conservation in hedgehog signaling: induction of a chicken patched homolog by Sonic hedgehog in the developing limb. Development 122, 1225-1233
-
(1996)
Development
, vol.122
, pp. 1225-1233
-
-
Marigo, V.1
Scott, M.P.2
Johnson, R.L.3
Goodrich, L.V.4
Tabin, C.J.5
-
20
-
-
0031989439
-
Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog
-
Motoyama, J., Takabatake, T., Takeshima, K. and Hui, C. (1998) Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog [Letter]. Nat. Genet. 18, 104-106
-
(1998)
Nat. Genet.
, vol.18
, pp. 104-106
-
-
Motoyama, J.1
Takabatake, T.2
Takeshima, K.3
Hui, C.4
-
21
-
-
0032506115
-
Characterization of two patched receptors for the vertebrate hedgehog protein family
-
Carpenter, D., Stone, D. M., Brush, J., Ryan, A., Armanini, M., Frantz, G., Rosenthal, A. and de Sauvage, F. J. (1998) Characterization of two patched receptors for the vertebrate hedgehog protein family. Proc. Natl. Acad. Sci. U.S.A. 95, 13630-13634
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 13630-13634
-
-
Carpenter, D.1
Stone, D.M.2
Brush, J.3
Ryan, A.4
Armanini, M.5
Frantz, G.6
Rosenthal, A.7
De Sauvage, F.J.8
-
22
-
-
0034751805
-
Suppression of hair follicle development inhibits induction of sonic hedgehog, patched, and patched-2 in hair germs in mice
-
Yamago, G., Takata, Y., Furuta, I., Urase, K., Momoi, T. and Huh, N. (2001) Suppression of hair follicle development inhibits induction of sonic hedgehog, patched, and patched-2 in hair germs in mice. Arch. Dermatol. Res. 293, 435-441
-
(2001)
Arch. Dermatol. Res.
, vol.293
, pp. 435-441
-
-
Yamago, G.1
Takata, Y.2
Furuta, I.3
Urase, K.4
Momoi, T.5
Huh, N.6
-
23
-
-
0032898184
-
Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene in basal cell carcinoma and medulloblastoma on chromosome 1p32
-
Smyth, I., Narang, M. A., Evans, T., Heimann, C., Nakamura, Y., Chenevix-Trench, G., Pietsch, T., Wicking, C. and Wainwright, B. J. (1999) Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene in basal cell carcinoma and medulloblastoma on chromosome 1p32. Hum. Mol. Genet. 8, 291-297
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 291-297
-
-
Smyth, I.1
Narang, M.A.2
Evans, T.3
Heimann, C.4
Nakamura, Y.5
Chenevix-Trench, G.6
Pietsch, T.7
Wicking, C.8
Wainwright, B.J.9
-
24
-
-
0033194243
-
Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1
-
Kogerman, P., Grimm, T., Kogerman, L., Krause, D., Unden, A. B., Sandstedt, B., Toftgard, R. and Zaphiropoulos, P. G. (1999) Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1. Nat. Cell Biol. 1, 312-319
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 312-319
-
-
Kogerman, P.1
Grimm, T.2
Kogerman, L.3
Krause, D.4
Unden, A.B.5
Sandstedt, B.6
Toftgard, R.7
Zaphiropoulos, P.G.8
-
25
-
-
0031913524
-
Activating Smoothened mutations in sporadic basal-cell carcinoma
-
Xie, J., Murone, M., Luoh, S. M., Ryan, A., Gu, Q., Zhang, C., Bonifas, J. M., Lam, C. W., Hynes, M., Goddard, A. et al. (1998) Activating Smoothened mutations in sporadic basal-cell carcinoma. Nature (London) 391, 90-92
-
(1998)
Nature (London)
, vol.391
, pp. 90-92
-
-
Xie, J.1
Murone, M.2
Luoh, S.M.3
Ryan, A.4
Gu, Q.5
Zhang, C.6
Bonifas, J.M.7
Lam, C.W.8
Hynes, M.9
Goddard, A.10
-
26
-
-
0031899024
-
Related membrane domains in proteins of sterol sensing and cell signaling provide a glimpse of treasures still buried within the dynamic realm of intracellular metabolic regulation
-
Osborne, T. F. and Rosenfeld, J. M. (1998) Related membrane domains in proteins of sterol sensing and cell signaling provide a glimpse of treasures still buried within the dynamic realm of intracellular metabolic regulation. Curr. Opin. Lipidol. 9, 137-140
-
(1998)
Curr. Opin. Lipidol.
, vol.9
, pp. 137-140
-
-
Osborne, T.F.1
Rosenfeld, J.M.2
-
27
-
-
0037158748
-
Patched acts catalytically to suppress the activity of Smoothened
-
Taipale, J., Cooper, M. K., Maiti, T. and Beachy, P. A. (2002) Patched acts catalytically to suppress the activity of Smoothened. Nature (London) 418, 892-897
-
(2002)
Nature (London)
, vol.418
, pp. 892-897
-
-
Taipale, J.1
Cooper, M.K.2
Maiti, T.3
Beachy, P.A.4
-
28
-
-
0034682719
-
Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened
-
Cambridge, Mass.
-
Denef, N., Neubuser, D., Perez, L. and Cohen, S. M. (2000) Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened. Cell (Cambridge, Mass.) 102, 521-531
-
(2000)
Cell
, vol.102
, pp. 521-531
-
-
Denef, N.1
Neubuser, D.2
Perez, L.3
Cohen, S.M.4
-
29
-
-
12944272018
-
Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1
-
Incardona, J. P., Lee, J. H., Robertson, C. P., Enga, K., Kapur, R. P. and Roelink, H. (2000) Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1. Proc. Natl. Acad. Sci. U.S.A. 97, 12044-12049
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 12044-12049
-
-
Incardona, J.P.1
Lee, J.H.2
Robertson, C.P.3
Enga, K.4
Kapur, R.P.5
Roelink, H.6
-
30
-
-
0034738979
-
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
-
Taipale, J., Chen, J. K., Cooper, M. K., Wang, B., Mann, R. K., Milenkovic, L., Scott, M. P. and Beachy, P. A. (2000) Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine. Nature (London) 406, 1005-1009
-
(2000)
Nature (London)
, vol.406
, pp. 1005-1009
-
-
Taipale, J.1
Chen, J.K.2
Cooper, M.K.3
Wang, B.4
Mann, R.K.5
Milenkovic, L.6
Scott, M.P.7
Beachy, P.A.8
-
31
-
-
0035179136
-
GLI1 localization in the germinal epithelial cells alternates between cytoplasm and nucleus: Upregulation in transgenic mice blocks spermatogenesis in pachytene
-
Kroft, T. L., Patterson, J., Won Yoon, J., Doglio, L., Walterhouse, D. O., Iannaccone, P. M. and Goldberg, E. (2001) GLI1 localization in the germinal epithelial cells alternates between cytoplasm and nucleus: upregulation in transgenic mice blocks spermatogenesis in pachytene. Biol. Reprod. 65, 1663-1671
-
(2001)
Biol. Reprod.
, vol.65
, pp. 1663-1671
-
-
Kroft, T.L.1
Patterson, J.2
Won Yoon, J.3
Doglio, L.4
Walterhouse, D.O.5
Iannaccone, P.M.6
Goldberg, E.7
-
32
-
-
0030912955
-
Gli family members are differentially expressed during the mitotic phase of spermatogenesis
-
Persengiev, S. P., Kondova, I. I., Millette, C. F. and Kilpatrick, D. L. (1997) Gli family members are differentially expressed during the mitotic phase of spermatogenesis. Oncogene 14, 2259-2264
-
(1997)
Oncogene
, vol.14
, pp. 2259-2264
-
-
Persengiev, S.P.1
Kondova, I.I.2
Millette, C.F.3
Kilpatrick, D.L.4
-
33
-
-
0030111258
-
Sertoli cell signaling by Desert hedgehog regulates the male germline
-
Bitgood, M. J., Shen, L. and McMahon, A. P. (1996) Sertoli cell signaling by Desert hedgehog regulates the male germline. Curr. Biol. 6, 298-304
-
(1996)
Curr. Biol.
, vol.6
, pp. 298-304
-
-
Bitgood, M.J.1
Shen, L.2
McMahon, A.P.3
-
34
-
-
0031964896
-
Molecular cytogenetic analysis of adult testicular germ cell tumours and identification of regions of consensus copy number change
-
Summersgill, B., Goker, H., Weber-Hall, S., Huddart, R., Horwich, A. and Shipley, J. (1998) Molecular cytogenetic analysis of adult testicular germ cell tumours and identification of regions of consensus copy number change. Br. J. Cancer 77, 305-313
-
(1998)
Br. J. Cancer
, vol.77
, pp. 305-313
-
-
Summersgill, B.1
Goker, H.2
Weber-Hall, S.3
Huddart, R.4
Horwich, A.5
Shipley, J.6
-
35
-
-
0035252410
-
Alternative splicing: Increasing diversity in the proteomic world
-
Graveley, B. R. (2001) Alternative splicing: increasing diversity in the proteomic world. Trends Genet. 17, 100-107
-
(2001)
Trends Genet.
, vol.17
, pp. 100-107
-
-
Graveley, B.R.1
-
36
-
-
0037172658
-
Sonic hedgehog induces the segregation of patched and smoothened in endosomes
-
Incardona, J. P., Gruenberg, J. and Roelink, H. (2002) Sonic hedgehog induces the segregation of patched and smoothened in endosomes. Curr. Biol. 12, 983-995
-
(2002)
Curr. Biol.
, vol.12
, pp. 983-995
-
-
Incardona, J.P.1
Gruenberg, J.2
Roelink, H.3
-
37
-
-
18644368453
-
Small-molecule modulators of Hedgehog signaling: Identification and characterization of Smoothened agonists and antagonists
-
Frank-Kamenetsky, M., Zhang, X. M., Bottega, S., Guicherit, O., Wichterle, H., Dudek, H., Bumcrot, D., Wang, F. Y., Jones, S., Shulok, J. et al. (2002) Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists. J. Biol. 1, 10
-
(2002)
J. Biol.
, vol.1
, pp. 10
-
-
Frank-Kamenetsky, M.1
Zhang, X.M.2
Bottega, S.3
Guicherit, O.4
Wichterle, H.5
Dudek, H.6
Bumcrot, D.7
Wang, F.Y.8
Jones, S.9
Shulok, J.10
-
38
-
-
0035504214
-
Ptc1 and Ptc2 transcripts provide distinct readouts of Hedgehog signaling activity during chick embryogenesis
-
Pearse, II, R. V., Vogan, K. J. and Tabin, C. J. (2001) Ptc1 and Ptc2 transcripts provide distinct readouts of Hedgehog signaling activity during chick embryogenesis. Dev. Biol. 239, 15-29
-
(2001)
Dev. Biol.
, vol.239
, pp. 15-29
-
-
Pearse II, R.V.1
Vogan, K.J.2
Tabin, C.J.3
-
39
-
-
0033155805
-
The Shh signalling pathway in early tooth development
-
Hardcastle, Z., Hui, C. C. and Sharpe, P. T. (1999) The Shh signalling pathway in early tooth development. Cell. Mol. Biol. 45, 567-578
-
(1999)
Cell. Mol. Biol.
, vol.45
, pp. 567-578
-
-
Hardcastle, Z.1
Hui, C.C.2
Sharpe, P.T.3
-
40
-
-
13144259688
-
Sonic hedgehog signaling is essential for hair development
-
St-Jacques, B., Dassule, H. R., Karavanova, I., Botchkarev, V. A., Li, J., Danielian, P. S., McMahon, J. A., Lewis, P. M., Paus, R. and McMahon, A. P. (1998) Sonic hedgehog signaling is essential for hair development. Curr. Biol. 8, 1058-1068
-
(1998)
Curr. Biol.
, vol.8
, pp. 1058-1068
-
-
St-Jacques, B.1
Dassule, H.R.2
Karavanova, I.3
Botchkarev, V.A.4
Li, J.5
Danielian, P.S.6
McMahon, J.A.7
Lewis, P.M.8
Paus, R.9
McMahon, A.P.10
-
41
-
-
0035374351
-
The sonic hedgehog receptor patched associates with caveolin-1 in cholesterol-rich microdomains of the plasma membrane
-
Karpen, H. E., Bukowski, J. T., Hughes, T., Gratton, J. P., Sessa, W. C. and Gailani, M. R. (2001) The sonic hedgehog receptor patched associates with caveolin-1 in cholesterol-rich microdomains of the plasma membrane. J. Biol. Chem. 276, 19503-19511
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19503-19511
-
-
Karpen, H.E.1
Bukowski, J.T.2
Hughes, T.3
Gratton, J.P.4
Sessa, W.C.5
Gailani, M.R.6
-
42
-
-
0034687244
-
Patched represses the Hedgehog signalling pathway by promoting modification of the Smoothened protein
-
Ingham, P. W., Nystedt, S., Nakano, Y., Brown, W., Stark, D., van den Heuvel, M. and Taylor, A. M. (2000) Patched represses the Hedgehog signalling pathway by promoting modification of the Smoothened protein. Curr. Biol. 10, 1315-1318
-
(2000)
Curr. Biol.
, vol.10
, pp. 1315-1318
-
-
Ingham, P.W.1
Nystedt, S.2
Nakano, Y.3
Brown, W.4
Stark, D.5
Van Den Heuvel, M.6
Taylor, A.M.7
-
43
-
-
0030866154
-
Altered neural cell fates and medulloblastoma in mouse patched mutants
-
Goodrich, L. V., Milenkovic, L., Higgins, K. M. and Scott, M. P. (1997) Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 277, 1109-1113
-
(1997)
Science
, vol.277
, pp. 1109-1113
-
-
Goodrich, L.V.1
Milenkovic, L.2
Higgins, K.M.3
Scott, M.P.4
-
44
-
-
0031837454
-
Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome
-
Hahn, H., Wojnowski, L., Zimmer, A. M., Hall, J., Miller, G. and Zimmer, A. (1998) Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome. Nat. Med. 4, 619-622
-
(1998)
Nat. Med.
, vol.4
, pp. 619-622
-
-
Hahn, H.1
Wojnowski, L.2
Zimmer, A.M.3
Hall, J.4
Miller, G.5
Zimmer, A.6
-
45
-
-
0037072736
-
Several Patched1 missense mutations display activity in patched1-deficient fibroblasts
-
Bailey, E. C., Milenkovic, L., Scott, M. P., Collawn, J. F. and Johnson, R. L. (2002) Several PATCHED1 missense mutations display activity in patched1-deficient fibroblasts. J. Biol. Chem. 277, 33632-33640
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 33632-33640
-
-
Bailey, E.C.1
Milenkovic, L.2
Scott, M.P.3
Collawn, J.F.4
Johnson, R.L.5
-
46
-
-
0034055649
-
Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation
-
Park, H. L., Bai, C., Platt, K. A., Matise, M. P., Beeghly, A., Hui, C. C., Nakashima, M. and Joyner, A. L. (2000) Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation. Development 127, 1593-1605
-
(2000)
Development
, vol.127
, pp. 1593-1605
-
-
Park, H.L.1
Bai, C.2
Platt, K.A.3
Matise, M.P.4
Beeghly, A.5
Hui, C.C.6
Nakashima, M.7
Joyner, A.L.8
|