-
1
-
-
0027496895
-
Mice carrying null mutations of the genes encoding insulin-like growth factor-1 (IGF-1) and type-1 IGF receptor (IGF1R)
-
Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A. Mice carrying null mutations of the genes encoding insulin-like growth factor-1 (IGF-1) and type-1 IGF receptor (IGF1R). Cell 1993; 75: 59-72
-
(1993)
Cell
, vol.75
, pp. 59-72
-
-
Liu, J.P.1
Baker, J.2
Perkins, A.S.3
Robertson, E.J.4
Efstratiadis, A.5
-
2
-
-
0027423419
-
Role of insulin-like growth factors in embryonic and postnatal growth
-
Baker J, Liu JP, Robertson EJ, Efstratiadis A. Role of insulin-like growth factors in embryonic and postnatal growth. Cell 1993; 75: 73-82
-
(1993)
Cell
, vol.75
, pp. 73-82
-
-
Baker, J.1
Liu, J.P.2
Robertson, E.J.3
Efstratiadis, A.4
-
3
-
-
0034453098
-
The effects of insulin-like growth factors on tumorigenesis and neoplastic growth
-
Khandwala HM, McCutcheon IE, Flyvbjerg A, Friend KE. The effects of insulin-like growth factors on tumorigenesis and neoplastic growth. Endocr Rev 2000; 21: 215-244
-
(2000)
Endocr Rev
, vol.21
, pp. 215-244
-
-
Khandwala, H.M.1
McCutcheon, I.E.2
Flyvbjerg, A.3
Friend, K.E.4
-
4
-
-
0032885494
-
Expression of insulin-like growth factor-1 receptor in human colorectal cancer
-
Hakam A, Yeatman TJ, Mora L, Marcet G, Nicosia SV, Karl RC, Coppola D. Expression of insulin-like growth factor-1 receptor in human colorectal cancer. Hum Pathol 1999; 30: 1128-1133
-
(1999)
Hum Pathol
, vol.30
, pp. 1128-1133
-
-
Hakam, A.1
Yeatman, T.J.2
Mora, L.3
Marcet, G.4
Nicosia, S.V.5
Karl, R.C.6
Coppola, D.7
-
5
-
-
0033974692
-
Expression of insulin-like growth factor-1 receptor (IGF-1R) and p27Kip1 in melanocytic tumors: A potential regulatory role of IGF-1 pathway in distribution of p27Kip1 between different cyclins
-
Kanter-Lewensohn L, Dricu A, Girnita L, Wejde J, Larsson O. Expression of insulin-like growth factor-1 receptor (IGF-1R) and p27Kip1 in melanocytic tumors: a potential regulatory role of IGF-1 pathway in distribution of p27Kip1 between different cyclins. Growth Factors 2000; 17: 193-202
-
(2000)
Growth Factors
, vol.17
, pp. 193-202
-
-
Kanter-Lewensohn, L.1
Dricu, A.2
Girnita, L.3
Wejde, J.4
Larsson, O.5
-
6
-
-
0028997487
-
Insulin-like growth-factor-i overexpression in human pancreatic-cancer -evidence for autocrine and paracrine roles
-
Bergmann U, Funatomi H, Yokoyama M, Berger HG, Korc M. Insulin-like growth-factor-i overexpression in human pancreatic-cancer -evidence for autocrine and paracrine roles. Cancer Res 1995; 55: 2007-2011
-
(1995)
Cancer Res
, vol.55
, pp. 2007-2011
-
-
Bergmann, U.1
Funatomi, H.2
Yokoyama, M.3
Berger, H.G.4
Korc, M.5
-
7
-
-
0037092971
-
Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease
-
Hellawell GO, Turner GD, Davies DR, Poulsom R, Brewster SF, Macaulay VM. Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease. Cancer Res 2002; 62: 2942-2950
-
(2002)
Cancer Res
, vol.62
, pp. 2942-2950
-
-
Hellawell, G.O.1
Turner, G.D.2
Davies, D.R.3
Poulsom, R.4
Brewster, S.F.5
Macaulay, V.M.6
-
8
-
-
0037300604
-
The IGFI receptor gene: A molecular target for disrupted transcription factors
-
Werner H, Roberts CT Jr. The IGFI receptor gene: a molecular target for disrupted transcription factors Genes Chromosomes Cancer 2003; 36: 113-120
-
(2003)
Genes Chromosomes Cancer
, vol.36
, pp. 113-120
-
-
Werner, H.1
Roberts Jr., C.T.2
-
9
-
-
0031558028
-
The IGF-I receptor in cell growth, transformation and apoptosis
-
Baserga R, Hongo A, Rubini M, Prisco M, Valentinis B. The IGF-I receptor in cell growth, transformation and apoptosis. Biochim Biophys Acta 1997; 1332: F105-126
-
(1997)
Biochim Biophys Acta
, vol.1332
-
-
Baserga, R.1
Hongo, A.2
Rubini, M.3
Prisco, M.4
Valentinis, B.5
-
10
-
-
0242288111
-
Targeting the type 1 insulin-like growth factor receptor as anticancer treatment
-
Bohula E, Playford M, Macaulay V. Targeting the type 1 insulin-like growth factor receptor as anticancer treatment. Anticancer Drugs 2003; 14: 669-682
-
(2003)
Anticancer Drugs
, vol.14
, pp. 669-682
-
-
Bohula, E.1
Playford, M.2
Macaulay, V.3
-
11
-
-
0030738695
-
Insulin-like-growth-factor-1 (IGF-1) alters drug-sensitivity of HBL100 human breast-cancer cells by inhibition of apoptosis induced by diverse anticancer drugs
-
Dunn SE, Hardman RA, Kari FW, Barrett JC. Insulin-like-growth-factor-1 (IGF-1) alters drug-sensitivity of HBL100 human breast-cancer cells by inhibition of apoptosis induced by diverse anticancer drugs. Cancer Res 1997; 57: 2687-2693
-
(1997)
Cancer Res
, vol.57
, pp. 2687-2693
-
-
Dunn, S.E.1
Hardman, R.A.2
Kari, F.W.3
Barrett, J.C.4
-
12
-
-
0029134568
-
Insulin-like growth factor-1 inhibits cell death induced by anticancer drugs in the MCF-7 cells: Involvement of growth factors in drug resistance
-
Geier A, Beery R, Haimsohn M, Karasik A. Insulin-like growth factor-1 inhibits cell death induced by anticancer drugs in the MCF-7 cells: involvement of growth factors in drug resistance. Cancer Invest 1995; 13: 480-486
-
(1995)
Cancer Invest
, vol.13
, pp. 480-486
-
-
Geier, A.1
Beery, R.2
Haimsohn, M.3
Karasik, A.4
-
13
-
-
0028852556
-
Insulin-like growth factor I (IGF-I) and the IGF-I receptor prevent etoposide-induced apoptosis
-
Sell C, Baserga R, Rubin R. Insulin-like growth factor I (IGF-I) and the IGF-I receptor prevent etoposide-induced apoptosis. Cancer Res 1995; 55: 303-306
-
(1995)
Cancer Res
, vol.55
, pp. 303-306
-
-
Sell, C.1
Baserga, R.2
Rubin, R.3
-
14
-
-
0035915421
-
Insulin-like growth factor-1 receptor signaling and resistance to trastuzumab (Herceptin)
-
Lu Y, Zi X, Zhao Y, Mascarenhas D, Pollak M. Insulin-like growth factor-1 receptor signaling and resistance to trastuzumab (Herceptin). J Natl Cancer Inst 2001; 93: 1852-1857
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1852-1857
-
-
Lu, Y.1
Zi, X.2
Zhao, Y.3
Mascarenhas, D.4
Pollak, M.5
-
15
-
-
0036141447
-
Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide3-kinase signaling
-
Chakravarti A, Loeffler JS, Dyson NJ. Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide3-kinase signaling. Cancer Res 2002; 62: 200-207
-
(2002)
Cancer Res
, vol.62
, pp. 200-207
-
-
Chakravarti, A.1
Loeffler, J.S.2
Dyson, N.J.3
-
16
-
-
0033200172
-
Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage
-
McMenamin ME, Soung P, Perera S, Kaplan I, Loda M, Sellers WR. Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage. Cancer Res 1999; 59: 4291-4296
-
(1999)
Cancer Res
, vol.59
, pp. 4291-4296
-
-
McMenamin, M.E.1
Soung, P.2
Perera, S.3
Kaplan, I.4
Loda, M.5
Sellers, W.R.6
-
17
-
-
0036828097
-
Constitutive activation of insulin receptor substrate 1 is a frequent event in human tumors: Therapeutic implications
-
Chang Q, Li Y, White MF, Fletcher JA, Xiao S. Constitutive activation of insulin receptor substrate 1 is a frequent event in human tumors: therapeutic implications. Cancer Res 2002; 62: 6035-6038
-
(2002)
Cancer Res
, vol.62
, pp. 6035-6038
-
-
Chang, Q.1
Li, Y.2
White, M.F.3
Fletcher, J.A.4
Xiao, S.5
-
18
-
-
0032827420
-
Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis
-
Peruzzi F, Prisco M, Dews M, Salomoni P, Grassilli E, Romano G, Calabretta B, Baserga R. Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis. Mol Cell Biol 1999; 19: 7203-7215
-
(1999)
Mol Cell Biol
, vol.19
, pp. 7203-7215
-
-
Peruzzi, F.1
Prisco, M.2
Dews, M.3
Salomoni, P.4
Grassilli, E.5
Romano, G.6
Calabretta, B.7
Baserga, R.8
-
19
-
-
0035823635
-
Cooperative regulation of the invasive and metastatic phenotypes by different domains of the type I insulin-like growth factor receptor beta subunit
-
Brodt P, Fallavollita L, Khatib AM, Samani AA, Zhang D. Cooperative regulation of the invasive and metastatic phenotypes by different domains of the type I insulin-like growth factor receptor beta subunit. J Biol Chem 2001; 276: 33 608-33 615
-
(2001)
J Biol Chem
, vol.276
, pp. 33608-33615
-
-
Brodt, P.1
Fallavollita, L.2
Khatib, A.M.3
Samani, A.A.4
Zhang, D.5
-
20
-
-
0031040543
-
Insulin-like growth-factors as regulators of cell motility - Signaling mechanisms
-
Leventhal PS, Feldman EL. Insulin-like growth-factors as regulators of cell motility - signaling mechanisms. Trends Endocrinol Metab 1997; 8: 1-6
-
(1997)
Trends Endocrinol Metab
, vol.8
, pp. 1-6
-
-
Leventhal, P.S.1
Feldman, E.L.2
-
21
-
-
0034710915
-
Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin
-
Playford MP, Bicknell D, Bodmer WF, Macaulay VM. Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin. Proc Natl Acad Sci USA 2000; 97: 12 103-12 108
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 12103-12108
-
-
Playford, M.P.1
Bicknell, D.2
Bodmer, W.F.3
Macaulay, V.M.4
-
22
-
-
0033179378
-
Expression of insulin-like growth factor-1 receptor in synovial sarcoma: Association with an aggressive phenotype
-
Xie Y, Skytting B, Nilsson G, Brodin B, Larsson O. Expression of insulin-like growth factor-1 receptor in synovial sarcoma: association with an aggressive phenotype. Cancer Res 1999; 59: 3588-3591
-
(1999)
Cancer Res
, vol.59
, pp. 3588-3591
-
-
Xie, Y.1
Skytting, B.2
Nilsson, G.3
Brodin, B.4
Larsson, O.5
-
23
-
-
0035195965
-
Inhibition of carcinoma cell growth and metastasis by a vesicular stomatitis virus G-pseudotyped retrovector expressing type I insulin-like growth factor receptor antisense
-
Samani AA, Fallavollita L, Jaalouk DE, Galipeau J, Brodt P. Inhibition of carcinoma cell growth and metastasis by a vesicular stomatitis virus G-pseudotyped retrovector expressing type I insulin-like growth factor receptor antisense. Hum Gene Ther 2001; 12: 1969-1977
-
(2001)
Hum Gene Ther
, vol.12
, pp. 1969-1977
-
-
Samani, A.A.1
Fallavollita, L.2
Jaalouk, D.E.3
Galipeau, J.4
Brodt, P.5
-
24
-
-
0037455716
-
Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling
-
Zhang D, Brodt P. Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling. Oncogene 2003; 22: 974-982
-
(2003)
Oncogene
, vol.22
, pp. 974-982
-
-
Zhang, D.1
Brodt, P.2
-
25
-
-
0037444268
-
Vascular endothelial growth factor C expression and lymph node metastasis are regulated by the type I insulin-like growth factor receptor
-
Tang Y, Zhang D, Fallavollita L, Brodt P. Vascular endothelial growth factor C expression and lymph node metastasis are regulated by the type I insulin-like growth factor receptor. Cancer Res 2003; 63: 1166-1171
-
(2003)
Cancer Res
, vol.63
, pp. 1166-1171
-
-
Tang, Y.1
Zhang, D.2
Fallavollita, L.3
Brodt, P.4
-
26
-
-
0036559535
-
Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis
-
Lopez T, Hanahan D. Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis. Cancer Cell 2002; 1: 339-353
-
(2002)
Cancer Cell
, vol.1
, pp. 339-353
-
-
Lopez, T.1
Hanahan, D.2
-
27
-
-
0033135898
-
The insulin-like growth factor axis and prostate cancer: Lessons from the transgenic adenocarcinoma of mouse prostate (TRAMP) model
-
Kaplan PJ, Mohan S, Cohen P, Foster BA, Greenberg NM. The insulin-like growth factor axis and prostate cancer: lessons from the transgenic adenocarcinoma of mouse prostate (TRAMP) model. Cancer Res 1999; 59: 2203-2209
-
(1999)
Cancer Res
, vol.59
, pp. 2203-2209
-
-
Kaplan, P.J.1
Mohan, S.2
Cohen, P.3
Foster, B.A.4
Greenberg, N.M.5
-
28
-
-
0034682328
-
IGF-I receptor signaling in a prostatic cancer cell line with a PTEN mutation
-
Reiss K, Wang JY, Romano G, Furnari FB, Cavenee WK, Morrione A, Tu X, Baserga R. IGF-I receptor signaling in a prostatic cancer cell line with a PTEN mutation. Oncogene 2000; 19: 2687-2694
-
(2000)
Oncogene
, vol.19
, pp. 2687-2694
-
-
Reiss, K.1
Wang, J.Y.2
Romano, G.3
Furnari, F.B.4
Cavenee, W.K.5
Morrione, A.6
Tu, X.7
Baserga, R.8
-
29
-
-
0037112511
-
Reduced expression of insulin-like growth factor I receptors in MCF-7 breast cancer cells leads to a more metastatic phenotype
-
Pennisi PA, Barr V, Nunez NP, Stannard B, Le Roith D. Reduced expression of insulin-like growth factor I receptors in MCF-7 breast cancer cells leads to a more metastatic phenotype. Cancer Res 2002; 62: 6529-6537
-
(2002)
Cancer Res
, vol.62
, pp. 6529-6537
-
-
Pennisi, P.A.1
Barr, V.2
Nunez, N.P.3
Stannard, B.4
Le Roith, D.5
-
30
-
-
0032932822
-
Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells
-
Frasca F, Pandini G, Scalia P, Sciacca L, Mineo R, Costantino A, Goldfine ID, Belfiore A, Vigneri R. Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells. Mol Cell Biol 1999; 19: 3278-3288
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3278-3288
-
-
Frasca, F.1
Pandini, G.2
Scalia, P.3
Sciacca, L.4
Mineo, R.5
Costantino, A.6
Goldfine, I.D.7
Belfiore, A.8
Vigneri, R.9
-
31
-
-
0037191919
-
In IGF-I receptor-deficient leiomyosarcoma cells autocrine IGF-II induces cell invasion and protection from apoptosis via the insulin receptor isoform A
-
Sciacca L, Mineo R, Pandini G, Murabito A, Vigneri R, Belfiore A. In IGF-I receptor-deficient leiomyosarcoma cells autocrine IGF-II induces cell invasion and protection from apoptosis via the insulin receptor isoform A. Oncogene 2002; 21: 8240-8250
-
(2002)
Oncogene
, vol.21
, pp. 8240-8250
-
-
Sciacca, L.1
Mineo, R.2
Pandini, G.3
Murabito, A.4
Vigneri, R.5
Belfiore, A.6
-
32
-
-
0036963448
-
Co-targeting HER2/ErbB2 and insulin-like growth factor-1 receptors causes synergistic inhibition of growth in HER2-overexpressing breast cancer cells
-
Camirand A, Lu Y, Pollak M. Co-targeting HER2/ErbB2 and insulin-like growth factor-1 receptors causes synergistic inhibition of growth in HER2-overexpressing breast cancer cells. Med Sci Monit 2002; 8: BR521-526
-
(2002)
Med Sci Monit
, vol.8
-
-
Camirand, A.1
Lu, Y.2
Pollak, M.3
-
33
-
-
0022800838
-
Insulin-like growth factor I receptor primary structure: Comparison with insulin receptor suggests structural determinants that define functional specificity
-
Ullrich A, Gray A, Tam AW, Yang-Feng T, Tsubokawa M, Collins C, Henzel W, Le Bon T, Kathuria S, Chen E et al. Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. Embo J 1986; 5: 2503-2512
-
(1986)
Embo J
, vol.5
, pp. 2503-2512
-
-
Ullrich, A.1
Gray, A.2
Tam, A.W.3
Yang-Feng, T.4
Tsubokawa, M.5
Collins, C.6
Henzel, W.7
Le Bon, T.8
Kathuria, S.9
Chen, E.10
-
34
-
-
0035185571
-
Structure and autoregulation of the insulin-like growth factor 1 receptor kinase
-
Favelyukis S, Till JH, Hubbard SR, Miller WT. Structure and autoregulation of the insulin-like growth factor 1 receptor kinase. Nat Struct Biol 2001; 8: 1058-1063
-
(2001)
Nat Struct Biol
, vol.8
, pp. 1058-1063
-
-
Favelyukis, S.1
Till, J.H.2
Hubbard, S.R.3
Miller, W.T.4
-
35
-
-
0036782071
-
Structural biology of insulin and IGF1 receptors: Implications for drug design
-
De Meyts P, Whittaker J. Structural biology of insulin and IGF1 receptors: implications for drug design. Nat Rev Drug Discov 2002; 1: 769-783
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 769-783
-
-
De Meyts, P.1
Whittaker, J.2
-
36
-
-
0346209061
-
Characterization of potent and selective kinase inhibitors of IGF-IR
-
Garcia-Echeverria C, Brueggen J, Caparo H-G, Evans DB, Ferrari S, Fabbro D, Furet P, Geiger T, Liebetanz J, Marti A, Martiny-Baron G, Mestan J, Pearson MA, Ruetz S, Stolz B, Hofmann F. Characterization of potent and selective kinase inhibitors of IGF-IR. Proc Amer Assoc Cancer Res 2003; 44: 1008
-
(2003)
Proc Amer Assoc Cancer Res
, vol.44
, pp. 1008
-
-
Garcia-Echeverria, C.1
Brueggen, J.2
Caparo, H.-G.3
Evans, D.B.4
Ferrari, S.5
Fabbro, D.6
Furet, P.7
Geiger, T.8
Liebetanz, J.9
Marti, A.10
Martiny-Baron, G.11
Mestan, J.12
Pearson, M.A.13
Ruetz, S.14
Stolz, B.15
Hofmann, F.16
-
37
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001; 411: 494-498
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
38
-
-
0032700656
-
Molecular mechanisms of action of antisense drugs
-
Crooke ST. Molecular mechanisms of action of antisense drugs. Biochim Biophys Acta 1999; 1489: 31-44
-
(1999)
Biochim Biophys Acta
, vol.1489
, pp. 31-44
-
-
Crooke, S.T.1
-
39
-
-
0034798245
-
The experimental use of antisense oligonucleotides: A guide for the perplexed
-
Stein CA. The experimental use of antisense oligonucleotides: a guide for the perplexed. J Clin Invest 2001; 108: 641-644
-
(2001)
J Clin Invest
, vol.108
, pp. 641-644
-
-
Stein, C.A.1
-
40
-
-
0028140591
-
Features in the 5′ non-coding sequences of rabbit alpha and beta-globin mRNAs that affect translational efficiency
-
Kozak M. Features in the 5′ non-coding sequences of rabbit alpha and beta-globin mRNAs that affect translational efficiency. J Mol Biol 1994; 235: 95-110
-
(1994)
J Mol Biol
, vol.235
, pp. 95-110
-
-
Kozak, M.1
-
41
-
-
0027990403
-
Growth regulation of human glioblastoma T98G cells by insulin-like growth factor-1 and its receptor
-
Ambrose D, Resnicoff M, Coppola D, Sell C, Miura M, Jameson S, Baserga R, Rubin R. Growth regulation of human glioblastoma T98G cells by insulin-like growth factor-1 and its receptor. J Cell Physiol 1994; 159: 92-100
-
(1994)
J Cell Physiol
, vol.159
, pp. 92-100
-
-
Ambrose, D.1
Resnicoff, M.2
Coppola, D.3
Sell, C.4
Miura, M.5
Jameson, S.6
Baserga, R.7
Rubin, R.8
-
42
-
-
0028050256
-
Growth inhibition of human melanoma cells in nude mice by antisense strategies to the type 1 insulin-like growth factor receptor
-
Resnicoff M, Coppola D, Sell C, Rubin R, Ferrone S, Baserga R. Growth inhibition of human melanoma cells in nude mice by antisense strategies to the type 1 insulin-like growth factor receptor. Cancer Res 1994; 54: 4848-4850
-
(1994)
Cancer Res
, vol.54
, pp. 4848-4850
-
-
Resnicoff, M.1
Coppola, D.2
Sell, C.3
Rubin, R.4
Ferrone, S.5
Baserga, R.6
-
43
-
-
0028271497
-
Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-1) receptor are nontumorigenic and induce regression of wild-type tumors
-
Resnicoff M, Sell C, Rubini M, Coppola D, Ambrose D, Baserga R, Rubin R. Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-1) receptor are nontumorigenic and induce regression of wild-type tumors. Cancer Res 1994; 54: 2218-2222
-
(1994)
Cancer Res
, vol.54
, pp. 2218-2222
-
-
Resnicoff, M.1
Sell, C.2
Rubini, M.3
Coppola, D.4
Ambrose, D.5
Baserga, R.6
Rubin, R.7
-
44
-
-
0348100279
-
Retroviral transduction with antisense IGF-IR RNA inhibits glioblastoma growth and induces dormancy in an orthotopic brain tumor model
-
Samani AA, Zhu L, Nalbantoglu J, Brodt P. Retroviral transduction with antisense IGF-IR RNA inhibits glioblastoma growth and induces dormancy in an orthotopic brain tumor model. Proc Amer Assoc Cancer Res 2003; 44: 6505
-
(2003)
Proc Amer Assoc Cancer Res
, vol.44
, pp. 6505
-
-
Samani, A.A.1
Zhu, L.2
Nalbantoglu, J.3
Brodt, P.4
-
45
-
-
0029937307
-
Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo
-
Burfeind P, Chernicky CL, Rininsland F, Ilan J. Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo. Proc Natl Acad Sci USA 1996; 93: 7263-7168
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 7263-17168
-
-
Burfeind, P.1
Chernicky, C.L.2
Rininsland, F.3
Ilan, J.4
-
46
-
-
0029895283
-
Antitumor effects of an adenovirus expressing antisense insulin-like growth-factor-I receptor on human lung-cancer cell-lines
-
Lee CT, Wu S, Gabrilovich D, Chen HL, Nadafrahrov S, Ciernik IF, Carbone DP. Antitumor effects of an adenovirus expressing antisense insulin-like growth-factor-I receptor on human lung-cancer cell-lines. Cancer Res 1996; 56: 3038-3041
-
(1996)
Cancer Res
, vol.56
, pp. 3038-3041
-
-
Lee, C.T.1
Wu, S.2
Gabrilovich, D.3
Chen, H.L.4
Nadafrahrov, S.5
Ciernik, I.F.6
Carbone, D.P.7
-
47
-
-
0032401879
-
Inhibition of insulin-like growth factor I receptor expression in neuroblastoma cells induces the regression of established tumors in mice
-
Liu X, Turbyville T, Fritz A, Whitesell L. Inhibition of insulin-like growth factor I receptor expression in neuroblastoma cells induces the regression of established tumors in mice. Cancer Res 1998; 58: 5432-5438
-
(1998)
Cancer Res
, vol.58
, pp. 5432-5438
-
-
Liu, X.1
Turbyville, T.2
Fritz, A.3
Whitesell, L.4
-
48
-
-
0034115368
-
Treatment of human breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor inhibits cell growth, suppresses tumorigenesis, alters the metastatic potential, and prolongs survival in vivo
-
In Process Citation
-
Chernicky CL, Yi L, Tan H, Gan SU, Ilan J. Treatment of human breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor inhibits cell growth, suppresses tumorigenesis, alters the metastatic potential, and prolongs survival in vivo [In Process Citation]. Cancer Gene Ther 2000; 7: 384-395
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 384-395
-
-
Chernicky, C.L.1
Yi, L.2
Tan, H.3
Gan, S.U.4
Ilan, J.5
-
49
-
-
0033952237
-
Down-regulation of the insulin-like growth factor I receptor by antisense RNA can reverse the transformed phenotype of human cervical cancer cell lines
-
Nakamura K, Hongo A, Kodama J, Miyagi Y, Yoshinouchi M, Kudo T. Down-regulation of the insulin-like growth factor I receptor by antisense RNA can reverse the transformed phenotype of human cervical cancer cell lines. Cancer Res 2000; 60: 760-765
-
(2000)
Cancer Res
, vol.60
, pp. 760-765
-
-
Nakamura, K.1
Hongo, A.2
Kodama, J.3
Miyagi, Y.4
Yoshinouchi, M.5
Kudo, T.6
-
50
-
-
85047699134
-
Effectiveness of insulin-like growth factor I receptor antisense strategy against Ewing's sarcoma cells
-
Scotlandi K, Maini C, Manara MC, Benini S, Serra M, Cerisano V, Strammiello R, Baldini N, Lollini PL, Nanni P, Nicoletti G, Picci P. Effectiveness of insulin-like growth factor I receptor antisense strategy against Ewing's sarcoma cells. Cancer Gene Ther 2002; 9: 296-307
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 296-307
-
-
Scotlandi, K.1
Maini, C.2
Manara, M.C.3
Benini, S.4
Serra, M.5
Cerisano, V.6
Strammiello, R.7
Baldini, N.8
Lollini, P.L.9
Nanni, P.10
Nicoletti, G.11
Picci, P.12
-
51
-
-
0028086553
-
Antisense-mediated reduction in insulin-like growth factor-I receptor expression suppresses the malignant phenotype of a human alveolar rhabdomyosarcoma
-
Shapiro DN, Jones BG, Shapiro LH, Dias P, Houghton PJ. Antisense-mediated reduction in insulin-like growth factor-I receptor expression suppresses the malignant phenotype of a human alveolar rhabdomyosarcoma. J Clin Invest 1994; 94: 1235-1242
-
(1994)
J Clin Invest
, vol.94
, pp. 1235-1242
-
-
Shapiro, D.N.1
Jones, B.G.2
Shapiro, L.H.3
Dias, P.4
Houghton, P.J.5
-
52
-
-
0035377756
-
Blockage of IGF-1R signaling sensitizes urinary bladder cancer cells to mitomycin-mediated cytotoxicity
-
Sun HZ, Wu SF, Tu ZH. Blockage of IGF-1R signaling sensitizes urinary bladder cancer cells to mitomycin-mediated cytotoxicity. Cell Res 2001; 11: 107-115
-
(2001)
Cell Res
, vol.11
, pp. 107-115
-
-
Sun, H.Z.1
Wu, S.F.2
Tu, Z.H.3
-
53
-
-
0037326983
-
Chemosensitization of human prostate cancer using antisense agents targeting the type 1 insulin-like growth factor receptor
-
Hellawell GO, Ferguson DJ, Brewster SF, Macaulay VM. Chemosensitization of human prostate cancer using antisense agents targeting the type 1 insulin-like growth factor receptor. BJU Int 2003; 91: 271-277
-
(2003)
BJU Int
, vol.91
, pp. 271-277
-
-
Hellawell, G.O.1
Ferguson, D.J.2
Brewster, S.F.3
Macaulay, V.M.4
-
54
-
-
16944364325
-
Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation
-
Turner BC, Haffty BG, Narayanan L, Yuan J, Havre PA, Gumbs AA, Kaplan L, Burgaud JL, Carter D, Baserga R, Glazer PM. Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation. Cancer Res 1997; 57: 3079-3083
-
(1997)
Cancer Res
, vol.57
, pp. 3079-3083
-
-
Turner, B.C.1
Haffty, B.G.2
Narayanan, L.3
Yuan, J.4
Havre, P.A.5
Gumbs, A.A.6
Kaplan, L.7
Burgaud, J.L.8
Carter, D.9
Baserga, R.10
Glazer, P.M.11
-
55
-
-
0035811559
-
Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase
-
Macaulay VM, Salisbury AJ, Bohula EA, Playford MP, Smorodinsky NI, Shiloh Y. Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase. Oncogene 2001; 20: 4029-4040
-
(2001)
Oncogene
, vol.20
, pp. 4029-4040
-
-
Macaulay, V.M.1
Salisbury, A.J.2
Bohula, E.A.3
Playford, M.P.4
Smorodinsky, N.I.5
Shiloh, Y.6
-
56
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 2003; 3: 155-168
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
57
-
-
0027507179
-
Treatment and prevention of rat glioblastoma by immunogenic C6 cells expressing antisense insulin-like growth factor I RNA
-
Trojan J, Johnson TR, Rudin SD, Ilan J, Tykocinski ML. Treatment and prevention of rat glioblastoma by immunogenic C6 cells expressing antisense insulin-like growth factor I RNA. Science 1993; 259: 94-97
-
(1993)
Science
, vol.259
, pp. 94-97
-
-
Trojan, J.1
Johnson, T.R.2
Rudin, S.D.3
Ilan, J.4
Tykocinski, M.L.5
-
58
-
-
0030570401
-
Presence of MHC-I and B-7 molecules in rat and human glioma cells expressing antisense IGF-I mRNA
-
Trojan J, Duc HT, Upegui-Gonzalez LC, Hor F, Guo Y, Anthony D, Ilan J. Presence of MHC-I and B-7 molecules in rat and human glioma cells expressing antisense IGF-I mRNA. Neurosci Lett 1996; 212: 9-12
-
(1996)
Neurosci Lett
, vol.212
, pp. 9-12
-
-
Trojan, J.1
Duc, H.T.2
Upegui-Gonzalez, L.C.3
Hor, F.4
Guo, Y.5
Anthony, D.6
Ilan, J.7
-
59
-
-
0346839558
-
siRNA mediated downregulation of Her-2/neu oncogene upregulates MHC class I in Her-2/neu overexpressing tumor cells
-
Choudhury A, Seliger B, Bock M, Charo J, Kiessling R. siRNA mediated downregulation of Her-2/neu oncogene upregulates MHC class I in Her-2/neu overexpressing tumor cells. Proc Amer Assoc Cancer Res 2003; 44: 6503-n
-
(2003)
Proc Amer Assoc Cancer Res
, vol.44
, pp. 6503-n
-
-
Choudhury, A.1
Seliger, B.2
Bock, M.3
Charo, J.4
Kiessling, R.5
-
60
-
-
0035871490
-
Results of a pilot study involving the use of an antisense oligodeoxynucleotide directed against the insulin-like growth factor type I receptor in malignant astrocytomas
-
Andrews DW, Resnicoff M, Flanders AE, Kenyon L, Curtis M, Merli G, Baserga R, Iliakis G, Aiken RD. Results of a pilot study involving the use of an antisense oligodeoxynucleotide directed against the insulin-like growth factor type I receptor in malignant astrocytomas. J Clin Oncol 2001; 19: 2189-2200
-
(2001)
J Clin Oncol
, vol.19
, pp. 2189-2200
-
-
Andrews, D.W.1
Resnicoff, M.2
Flanders, A.E.3
Kenyon, L.4
Curtis, M.5
Merli, G.6
Baserga, R.7
Iliakis, G.8
Aiken, R.D.9
-
61
-
-
0035261255
-
Post-transcriptional gene silencing by double-stranded RNA
-
Hammond SM, Caudy AA, Hannon GJ. Post-transcriptional gene silencing by double-stranded RNA. Nat Rev Genet 2001; 2: 110-119
-
(2001)
Nat Rev Genet
, vol.2
, pp. 110-119
-
-
Hammond, S.M.1
Caudy, A.A.2
Hannon, G.J.3
-
62
-
-
0034084338
-
Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): Mechanism of action
-
Gil J, Esteban M. Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action. Apoptosis 2000; 5: 107-114
-
(2000)
Apoptosis
, vol.5
, pp. 107-114
-
-
Gil, J.1
Esteban, M.2
-
63
-
-
0031737516
-
Antisense RNA: Function and fate of duplex RNA in cells of higher eukaryotes
-
Kumar M, Carmichael GG. Antisense RNA: function and fate of duplex RNA in cells of higher eukaryotes. Microbiol Mol Biol Rev 1998; 62: 1415-1434
-
(1998)
Microbiol Mol Biol Rev
, vol.62
, pp. 1415-1434
-
-
Kumar, M.1
Carmichael, G.G.2
-
64
-
-
0037007007
-
Using RNA interference to identify genes required for RNA interference
-
Dudley NR, Labbe JC, Goldstein B. Using RNA interference to identify genes required for RNA interference. Proc Natl Acad Sci USA 2002; 99: 4191-4196
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 4191-4196
-
-
Dudley, N.R.1
Labbe, J.C.2
Goldstein, B.3
-
65
-
-
0035694237
-
Identification of essential genes in cultured mammalian cells using small interfering RNAs
-
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. Identification of essential genes in cultured mammalian cells using small interfering RNAs. J Cell Sci 2001; 114: 4557-4565
-
(2001)
J Cell Sci
, vol.114
, pp. 4557-4565
-
-
Harborth, J.1
Elbashir, S.M.2
Bechert, K.3
Tuschl, T.4
Weber, K.5
-
66
-
-
0037033788
-
Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells
-
Ohta T, Essner R, Ryu JH, Palazzo RE, Uetake Y, Kuriyama R. Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells. J Cell Biol 2002; 156: 87-99
-
(2002)
J Cell Biol
, vol.156
, pp. 87-99
-
-
Ohta, T.1
Essner, R.2
Ryu, J.H.3
Palazzo, R.E.4
Uetake, Y.5
Kuriyama, R.6
-
67
-
-
0038521255
-
The efficacy of small interfering RNAs targeted to the type 1 IGF receptor is influenced by secondary structure in the IGF1R transcript
-
Bohula EA, Salisbury AJ, Sohail M, Playford MP, Riedemann J, Southern EM, Macaulay VM. The efficacy of small interfering RNAs targeted to the type 1 IGF receptor is influenced by secondary structure in the IGF1R transcript. J Biol Chem 2003; 278: 15 991-15 997
-
(2003)
J Biol Chem
, vol.278
, pp. 15991-15997
-
-
Bohula, E.A.1
Salisbury, A.J.2
Sohail, M.3
Playford, M.P.4
Riedemann, J.5
Southern, E.M.6
Macaulay, V.M.7
-
68
-
-
0018788204
-
Site specific enzymatic cleavage of RNA
-
Donis-Keller H. Site specific enzymatic cleavage of RNA. Nucleic Acids Res 1979; 7: 179-192
-
(1979)
Nucleic Acids Res
, vol.7
, pp. 179-192
-
-
Donis-Keller, H.1
-
69
-
-
0034123916
-
Reversal of epidermal hyperproliferation in psoriasis by insulin-like growth factor I receptor antisense oligonucleotides
-
Wraight CJ, White PJ, McKean SC, Fogarty RD, Venables DJ, Liepe IJ, Edmondson SR, Werther GA. Reversal of epidermal hyperproliferation in psoriasis by insulin-like growth factor I receptor antisense oligonucleotides. Nat Biotechnol 2000; 18: 521-526
-
(2000)
Nat Biotechnol
, vol.18
, pp. 521-526
-
-
Wraight, C.J.1
White, P.J.2
McKean, S.C.3
Fogarty, R.D.4
Venables, D.J.5
Liepe, I.J.6
Edmondson, S.R.7
Werther, G.A.8
-
70
-
-
0026621339
-
Implication of RNA structure on antisense oligonucleotide hybridization kinetics
-
Lima WF, Monia BP, Ecker DJ, Freier SM. Implication of RNA structure on antisense oligonucleotide hybridization kinetics. Biochemistry 1992; 31: 12 055-12 061
-
(1992)
Biochemistry
, vol.31
, pp. 12055-12061
-
-
Lima, W.F.1
Monia, B.P.2
Ecker, D.J.3
Freier, S.M.4
-
71
-
-
0025678737
-
Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis
-
Michel F, Westhof E. Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis. J Mol Biol 1990; 216: 585-610
-
(1990)
J Mol Biol
, vol.216
, pp. 585-610
-
-
Michel, F.1
Westhof, E.2
-
72
-
-
0032890879
-
The folding of large RNAs studied by hybridization to arrays of complementary oligonucleotides
-
Sohail M, Akhtar S, Southern EM. The folding of large RNAs studied by hybridization to arrays of complementary oligonucleotides. RNA 1999; 5: 646-655
-
(1999)
RNA
, vol.5
, pp. 646-655
-
-
Sohail, M.1
Akhtar, S.2
Southern, E.M.3
-
73
-
-
0036043328
-
Oligonucleotide scanning arrays: Application to high-throughput screening for effective antisense reagents and the study of nucleic acid interactions
-
Sohail M, Southern EM. Oligonucleotide scanning arrays: application to high-throughput screening for effective antisense reagents and the study of nucleic acid interactions. Adv Biochem Eng Biotechnol 2002; 77: 43-56
-
(2002)
Adv Biochem Eng Biotechnol
, vol.77
, pp. 43-56
-
-
Sohail, M.1
Southern, E.M.2
-
74
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806-811
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
75
-
-
0037031576
-
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
-
Martinez J, Patkaniowska A, Urlaub H, Luhrmann R, Tuschl T. Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 2002; 110: 563-n
-
(2002)
Cell
, vol.110
, pp. 563-n
-
-
Martinez, J.1
Patkaniowska, A.2
Urlaub, H.3
Luhrmann, R.4
Tuschl, T.5
-
76
-
-
0036385852
-
Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo
-
Bertrand J-R, Pottier M, Vekris A, Opolon P, Maksimenko A, Malvy C. Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo. Biochem Biophys Res Commun 2002; 296: 1000-1004
-
(2002)
Biochem Biophys Res Commun
, vol.296
, pp. 1000-1004
-
-
Bertrand, J.-R.1
Pottier, M.2
Vekris, A.3
Opolon, P.4
Maksimenko, A.5
Malvy, C.6
-
77
-
-
0037682110
-
Varying the nucleic acid composition of siRNA molecules dramatically varies the duration and degree of gene silencing
-
Lamberton J, Christian A. Varying the nucleic acid composition of siRNA molecules dramatically varies the duration and degree of gene silencing. Mol Biotechnol 2003; 24: 111-120
-
(2003)
Mol Biotechnol
, vol.24
, pp. 111-120
-
-
Lamberton, J.1
Christian, A.2
-
78
-
-
0037019339
-
RNA interference in adult mice
-
McCaffrey AP, Meuse L, Pham TT, Conklin DS, Hannon GJ, Kay MA. RNA interference in adult mice. Nature 2002; 418: 38-39
-
(2002)
Nature
, vol.418
, pp. 38-39
-
-
McCaffrey, A.P.1
Meuse, L.2
Pham, T.T.3
Conklin, D.S.4
Hannon, G.J.5
Kay, M.A.6
-
79
-
-
0036726313
-
Stable suppression of tumorigenicity by virus-mediated RNA interference
-
Brummelkamp TR, Bernards R, Agami R. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2002; 2: 243-247
-
(2002)
Cancer Cell
, vol.2
, pp. 243-247
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
80
-
-
0037158901
-
Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi)
-
Wilda M, Fuchs U, Wossmann W, Borkhardt A. Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi). Oncogene 2002; 21: 5716-5724
-
(2002)
Oncogene
, vol.21
, pp. 5716-5724
-
-
Wilda, M.1
Fuchs, U.2
Wossmann, W.3
Borkhardt, A.4
-
81
-
-
0042173218
-
SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth
-
Filleur S, Courtin A, Ait-Si-Ali S, Guglielmi J, Merle C, Harel-Bellan A, Clezardin P, Cabon F. SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth. Cancer Res 2003; 63: 3919-3922
-
(2003)
Cancer Res
, vol.63
, pp. 3919-3922
-
-
Filleur, S.1
Courtin, A.2
Ait-Si-Ali, S.3
Guglielmi, J.4
Merle, C.5
Harel-Bellan, A.6
Clezardin, P.7
Cabon, F.8
-
82
-
-
0037243999
-
A methylated oligonucleotide inhibits IGF2 expression and enhances survival in a model of hepatocellular carcinoma
-
Yao X, Hu JF, Daniels M, Shiran H, Zhou X, Yan H, Lu H, Zeng Z, Wang Q, Li T, Hoffman AR. A methylated oligonucleotide inhibits IGF2 expression and enhances survival in a model of hepatocellular carcinoma. J Clin Invest 2003; 111: 265-273
-
(2003)
J Clin Invest
, vol.111
, pp. 265-273
-
-
Yao, X.1
Hu, J.F.2
Daniels, M.3
Shiran, H.4
Zhou, X.5
Yan, H.6
Lu, H.7
Zeng, Z.8
Wang, Q.9
Li, T.10
Hoffman, A.R.11
-
83
-
-
0036636074
-
Nucleic-acid therapeutics: Basic principles and recent applications
-
Opalinska JB, Gewirtz AM. Nucleic-acid therapeutics: basic principles and recent applications. Nat Rev Drug Discov 2002; 1: 503-514
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 503-514
-
-
Opalinska, J.B.1
Gewirtz, A.M.2
-
84
-
-
0042862923
-
Decreased expression of the insulin-like growth factor 1 receptor by ribozyme cleavage
-
Shaw LC, Afzal A, Lewin AS, Timmers AM, Spoerri PE, Grant MB. Decreased expression of the insulin-like growth factor 1 receptor by ribozyme cleavage. Invest Ophthalmol Vis Sci 2003; 44: 4105-4113
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 4105-4113
-
-
Shaw, L.C.1
Afzal, A.2
Lewin, A.S.3
Timmers, A.M.4
Spoerri, P.E.5
Grant, M.B.6
-
85
-
-
3042714343
-
Decreased expression of the mannose 6-phosphate/insulin-like growth factor-II receptor promotes growth of human breast cancer cells
-
Chen Z, Ge Y, Landman N, Kang JX. Decreased expression of the mannose 6-phosphate/insulin-like growth factor-II receptor promotes growth of human breast cancer cells. BMC Cancer 2002; 2: 18
-
(2002)
BMC Cancer
, vol.2
, pp. 18
-
-
Chen, Z.1
Ge, Y.2
Landman, N.3
Kang, J.X.4
-
86
-
-
0037292502
-
The role of insulin-like growth factor-II in cancer growth and progression evidenced by the use of ribozymes and prostate cancer progression models
-
Guo N, Ye JJ, Liang SJ, Mineo R, Li SL, Giannini S, Plymate SR, Sikes RA, Fujita-Yamaguchi Y. The role of insulin-like growth factor-II in cancer growth and progression evidenced by the use of ribozymes and prostate cancer progression models. Growth Horm IGF Res 2003; 13: 44-53
-
(2003)
Growth Horm IGF Res
, vol.13
, pp. 44-53
-
-
Guo, N.1
Ye, J.J.2
Liang, S.J.3
Mineo, R.4
Li, S.L.5
Giannini, S.6
Plymate, S.R.7
Sikes, R.A.8
Fujita-Yamaguchi, Y.9
-
87
-
-
0030987783
-
Suppression of insulin-like growth factor type I receptor by a triple-helix strategy inhibits IGF-I transcription and tumorigenic potential of rat C6 glioblastoma cells
-
Rininsland F, Johnson TR, Chernicky CL, Schulze E, Burfeind P, Ilan J. Suppression of insulin-like growth factor type I receptor by a triple-helix strategy inhibits IGF-I transcription and tumorigenic potential of rat C6 glioblastoma cells. Proc Natl Acad Sci USA 1997; 94: 5854-5859
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 5854-5859
-
-
Rininsland, F.1
Johnson, T.R.2
Chernicky, C.L.3
Schulze, E.4
Burfeind, P.5
Ilan, J.6
-
88
-
-
0348100278
-
Oligonucleotide therapies
-
Yarnold JR, Stratton M, McMillan TJ, (eds.). London: Chapman and Hall
-
Macaulay V. Oligonucleotide therapies. In: Yarnold JR, Stratton M, McMillan TJ, (eds.). Molecular Biology for Oncologists. 2nd ed. London: Chapman and Hall, 1996: 275-292
-
(1996)
Molecular Biology for Oncologists. 2nd Ed.
, pp. 275-292
-
-
Macaulay, V.1
-
89
-
-
0027052602
-
Control of gene expression by triple helix-forming oligonucleotides. The antigene strategy
-
Helene C, Thuong NT, Harel-Bellan A. Control of gene expression by triple helix-forming oligonucleotides. The antigene strategy. Ann N Y Acad Sci 1992; 660: 27-36
-
(1992)
Ann N Y Acad Sci
, vol.660
, pp. 27-36
-
-
Helene, C.1
Thuong, N.T.2
Harel-Bellan, A.3
-
90
-
-
0033594893
-
Normal growth and development in the absence of hepatic insulin-like growth factor I
-
Yakar S, Liu JL, Stannard B, Butler A, Accili D, Sauer B, LeRoith D. Normal growth and development in the absence of hepatic insulin-like growth factor I. Proc Natl Acad Sci USA 1999; 96: 7324-7329
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7324-7329
-
-
Yakar, S.1
Liu, J.L.2
Stannard, B.3
Butler, A.4
Accili, D.5
Sauer, B.6
LeRoith, D.7
-
91
-
-
0347664057
-
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
-
Holzenberger M, Dupont J, Ducos B, Leneuve P, Geloen A, Even PC, Cervera P, Le Bouc Y. IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 2003; 421: 182-187
-
(2003)
Nature
, vol.421
, pp. 182-187
-
-
Holzenberger, M.1
Dupont, J.2
Ducos, B.3
Leneuve, P.4
Geloen, A.5
Even, P.C.6
Cervera, P.7
Le Bouc, Y.8
-
92
-
-
0030717725
-
Insulin-like growth factors regulate neuronal differentiation and survival
-
Feldman EL, Sullivan KA, Kim B, Russell JW. Insulin-like growth factors regulate neuronal differentiation and survival. Neurobiol Dis 1997; 4: 201-214
-
(1997)
Neurobiol Dis
, vol.4
, pp. 201-214
-
-
Feldman, E.L.1
Sullivan, K.A.2
Kim, B.3
Russell, J.W.4
-
93
-
-
0034484498
-
Insulin-like growth factor-1 receptors and estrogen receptors interact in the promotion of neuronal survival and neuroprotection
-
Garcia-Segura LM, Cardona-Gomez GP, Chowen JA, Azcoitia I. Insulin-like growth factor-1 receptors and estrogen receptors interact in the promotion of neuronal survival and neuroprotection. J Neurocytol 2000; 29: 425-437
-
(2000)
J Neurocytol
, vol.29
, pp. 425-437
-
-
Garcia-Segura, L.M.1
Cardona-Gomez, G.P.2
Chowen, J.A.3
Azcoitia, I.4
-
94
-
-
0028890744
-
The insulin-like growth-factor-1 receptor - A key to tumor growth?
-
Baserga R. The insulin-like growth-factor-1 receptor - a key to tumor growth? Cancer Res 1995; 55: 249-252
-
(1995)
Cancer Res
, vol.55
, pp. 249-252
-
-
Baserga, R.1
-
95
-
-
0032845626
-
Antisense transgenics in animals
-
Erickson RP. Antisense transgenics in animals. Methods 1999; 18: 304-310
-
(1999)
Methods
, vol.18
, pp. 304-310
-
-
Erickson, R.P.1
-
96
-
-
0037313867
-
Receptor tyrosine kinases: The main targets for new anticancer therapy
-
Drevs J, Medinger M, Schmidt-Gersbach C, Weber R, Unger C. Receptor tyrosine kinases: the main targets for new anticancer therapy. Curr Drug Targets 2003; 4: 113-121
-
(2003)
Curr Drug Targets
, vol.4
, pp. 113-121
-
-
Drevs, J.1
Medinger, M.2
Schmidt-Gersbach, C.3
Weber, R.4
Unger, C.5
-
97
-
-
0034015113
-
Phosphorothioate oligodeoxynucleotides: What is their origin and what is unique about them?
-
Eckstein F. Phosphorothioate oligodeoxynucleotides: what is their origin and what is unique about them? Antisense Nucleic Acid Drug Dev 2000; 10: 117-121
-
(2000)
Antisense Nucleic Acid Drug Dev
, vol.10
, pp. 117-121
-
-
Eckstein, F.1
-
98
-
-
0036187489
-
Protein kinase A type I: A target for cancer therapy
-
Tortora G, Ciardiello F. Protein kinase A type I: a target for cancer therapy. Clin Cancer Res 2002; 8: 303-304
-
(2002)
Clin Cancer Res
, vol.8
, pp. 303-304
-
-
Tortora, G.1
Ciardiello, F.2
-
99
-
-
0033814862
-
Antisense approaches for the treatment of cancer
-
Monia BP, Holmlund J, Dorr FA. Antisense approaches for the treatment of cancer. Cancer Invest 2000; 18: 635-650
-
(2000)
Cancer Invest
, vol.18
, pp. 635-650
-
-
Monia, B.P.1
Holmlund, J.2
Dorr, F.A.3
-
100
-
-
0036846993
-
Antisense therapy for cancer - The time of truth
-
Jansen B, Zangemeister-Wittke U. Antisense therapy for cancer - the time of truth. Lancet Oncol 2002; 3: 672-683
-
(2002)
Lancet Oncol
, vol.3
, pp. 672-683
-
-
Jansen, B.1
Zangemeister-Wittke, U.2
-
101
-
-
0036864770
-
Trastuzumab use in breast cancer: Clinical issues
-
Horton J. Trastuzumab use in breast cancer: clinical issues. Cancer Control 2002; 9: 499-507
-
(2002)
Cancer Control
, vol.9
, pp. 499-507
-
-
Horton, J.1
-
102
-
-
0347470293
-
A fully human monoclonal antibody to the human IGF-1 receptor that blocks ligand-dependent signaling and inhibits the growth of multiple human tumors in nude mice
-
Ludwig DL, Burtrum D, Lu D, Anderson DM, Prewett M, Bassi R, Koo H, Jimenez X, Pereira DS, Apblett R, Kussie P, Bohlen P, Hicklin DJ, Zhu Z, Witte L. A fully human monoclonal antibody to the human IGF-1 receptor that blocks ligand-dependent signaling and inhibits the growth of multiple human tumors in nude mice. Proc Amer Assoc Cancer Res 2003; 44: 761
-
(2003)
Proc Amer Assoc Cancer Res
, vol.44
, pp. 761
-
-
Ludwig, D.L.1
Burtrum, D.2
Lu, D.3
Anderson, D.M.4
Prewett, M.5
Bassi, R.6
Koo, H.7
Jimenez, X.8
Pereira, D.S.9
Apblett, R.10
Kussie, P.11
Bohlen, P.12
Hicklin, D.J.13
Zhu, Z.14
Witte, L.15
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