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Volumn 58, Issue 23, 1998, Pages 5432-5438

Inhibition of insulin-like growth factor I receptor expression in neuroblastoma cells induces the regression of established tumors in mice

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; COMPLEMENTARY DNA; LIPOCORTIN 5; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

EID: 0032401879     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (87)

References (54)
  • 2
    • 0028890744 scopus 로고
    • The insulin-like growth factor 1 receptor: A key to tumor growth?
    • Baserga, R. The insulin-like growth factor 1 receptor: a key to tumor growth? Cancer Res., 55: 249-252, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 249-252
    • Baserga, R.1
  • 4
    • 0030980001 scopus 로고    scopus 로고
    • Neuroblastoma and insulin-like growth factor system. New insights and clinical perspectives
    • Cianfarani, S., and Rossi, P. Neuroblastoma and insulin-like growth factor system. New insights and clinical perspectives. Eur. J. Pediatr., 156: 256-261, 1997.
    • (1997) Eur. J. Pediatr. , vol.156 , pp. 256-261
    • Cianfarani, S.1    Rossi, P.2
  • 5
    • 0027423419 scopus 로고
    • Role of insulin-like growth factors in embryonic and postnatal growth
    • Baker, J., Liu, J-P., Robertson, E. J., and Efstratiadis, A. Role of insulin-like growth factors in embryonic and postnatal growth. Cell, 75: 73-82, 1993.
    • (1993) Cell , vol.75 , pp. 73-82
    • Baker, J.1    Liu, J.-P.2    Robertson, E.J.3    Efstratiadis, A.4
  • 6
    • 0024465983 scopus 로고
    • Autonomous growth of a human neuroblastoma cell line is mediated by insulin-like growth factor II
    • El-Badry, O., Romanus, J., Helman, L., Cooper, M., Rechler, M., and Israel, M. Autonomous growth of a human neuroblastoma cell line is mediated by insulin-like growth factor II. J. Clin. Investig., 84: 829-839, 1989.
    • (1989) J. Clin. Investig. , vol.84 , pp. 829-839
    • El-Badry, O.1    Romanus, J.2    Helman, L.3    Cooper, M.4    Rechler, M.5    Israel, M.6
  • 7
    • 3643079710 scopus 로고
    • Growth regulation of human neuroblastoma
    • C. Benz and T. L. Edison (eds.), Boston: Kluwer Academic
    • El-Badry, A., and Israel, M. Growth regulation of human neuroblastoma. In: C. Benz and T. L. Edison (eds.), Oncogenes and Tumor Suppressor Genes in Human Malignancies, pp. 105-128. Boston: Kluwer Academic, 1993.
    • (1993) Oncogenes and Tumor Suppressor Genes in Human Malignancies , pp. 105-128
    • El-Badry, A.1    Israel, M.2
  • 8
    • 0028884799 scopus 로고
    • Insulin-like growth factor II (IGF-II) in the pathogenesis of human neuroblastoma
    • Castle, V. P., Hanash, S. M., and Feldman, E. L. Insulin-like growth factor II (IGF-II) in the pathogenesis of human neuroblastoma. Am. J. Pathol., 147: 1790-1798, 1995.
    • (1995) Am. J. Pathol. , vol.147 , pp. 1790-1798
    • Castle, V.P.1    Hanash, S.M.2    Feldman, E.L.3
  • 10
    • 0029738916 scopus 로고    scopus 로고
    • Insulin-like growth factor I receptor prevents apoptosis and enhances neuroblastoma tumorigenesis
    • Singleton, J. R., Randolph, A. E., and Feldman, E. L. Insulin-like growth factor I receptor prevents apoptosis and enhances neuroblastoma tumorigenesis. Cancer Res., 56: 4522-4529, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 4522-4529
    • Singleton, J.R.1    Randolph, A.E.2    Feldman, E.L.3
  • 11
    • 0028271497 scopus 로고
    • Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-1) receptor are nontumorigenic and induce regression of wildtype tumors
    • Resnicoff, M., Sell, C., Rubini, M., Coppola, D., Ambrose, D., Baserga, R., and Rubin, R. Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-1) receptor are nontumorigenic and induce regression of wildtype tumors. Cancer Res., 54: 2218-2222, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 2218-2222
    • Resnicoff, M.1    Sell, C.2    Rubini, M.3    Coppola, D.4    Ambrose, D.5    Baserga, R.6    Rubin, R.7
  • 13
    • 0029125689 scopus 로고
    • Growth inhibition of MCF-7 breast cancer cells by stable expression of an insulin-like growth factor I receptor antisense ribonucleic acid
    • Neuenschwander, S., Roberts, C. T., Jr., and LeRoith, D. Growth inhibition of MCF-7 breast cancer cells by stable expression of an insulin-like growth factor I receptor antisense ribonucleic acid. Endocrinology, 136: 4298-4303, 1995.
    • (1995) Endocrinology , vol.136 , pp. 4298-4303
    • Neuenschwander, S.1    Roberts Jr., C.T.2    LeRoith, D.3
  • 14
    • 0028997487 scopus 로고
    • Insulin-like growth factor I overexpression in human pancreatic cancer: Evidence for autocrine and paracrine roles
    • Bergmann, U., Funatomi, H., Yokoyama, M., Beger, H. G., and Korc, M. Insulin-like growth factor I overexpression in human pancreatic cancer: evidence for autocrine and paracrine roles. Cancer Res., 55: 2007-2011, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 2007-2011
    • Bergmann, U.1    Funatomi, H.2    Yokoyama, M.3    Beger, H.G.4    Korc, M.5
  • 15
    • 0028050256 scopus 로고
    • Growth inhibition of human melanoma cells in nude mice by antisense strategies to the type 1 insulin-like growth factor receptor
    • Resnicoff, M., Coppola, D., Sell, C., Rubin, R., Ferrone, S., and Baserga, R. Growth inhibition of human melanoma cells in nude mice by antisense strategies to the type 1 insulin-like growth factor receptor. Cancer Res., 54: 4848-4850, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 4848-4850
    • Resnicoff, M.1    Coppola, D.2    Sell, C.3    Rubin, R.4    Ferrone, S.5    Baserga, R.6
  • 16
    • 0028086553 scopus 로고
    • Antisense-mediated reduction in insulin-like growth factor 1 receptor expression suppresses the malignant phenotype of a human alveolar rhabdomyosarcoma
    • Shapiro, D. N., Jones, B. G., Shapiro, L. H., Dias, P., and Houghton, P. J. Antisense-mediated reduction in insulin-like growth factor 1 receptor expression suppresses the malignant phenotype of a human alveolar rhabdomyosarcoma. J. Clin. Invest., 94: 1235-1242, 1994.
    • (1994) J. Clin. Invest. , vol.94 , pp. 1235-1242
    • Shapiro, D.N.1    Jones, B.G.2    Shapiro, L.H.3    Dias, P.4    Houghton, P.J.5
  • 17
    • 0027507179 scopus 로고
    • Treatment and prevention of rat glioblastoma by immunogenic C6 cells expressing antisense insulin-like growth factor 1 RNA
    • Washington DC
    • Trojan, J., Johnson, T., Rudin, S., Ilan, J., Tykocinski, M., and Ilan, J. Treatment and prevention of rat glioblastoma by immunogenic C6 cells expressing antisense insulin-like growth factor 1 RNA. Science (Washington DC), 259: 94-97, 1993.
    • (1993) Science , vol.259 , pp. 94-97
    • Trojan, J.1    Johnson, T.2    Rudin, S.3    Ilan, J.4    Tykocinski, M.5    Ilan, J.6
  • 18
    • 0026735230 scopus 로고
    • Loss of tumorigenicity of rat glioblastoma directed by episome-based antisense cDNA transcription of insulin-like growth factor I
    • Trojan, J., Blossey, B., Johnson, T., Rudin, S., Tykocinski, M., Ilan, J., and Ilan, J. Loss of tumorigenicity of rat glioblastoma directed by episome-based antisense cDNA transcription of insulin-like growth factor I. Proc. Natl. Acad. Sci. USA, 89: 4874-4878, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4874-4878
    • Trojan, J.1    Blossey, B.2    Johnson, T.3    Rudin, S.4    Tykocinski, M.5    Ilan, J.6    Ilan, J.7
  • 20
    • 0028332092 scopus 로고
    • Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts
    • Sell, C., Dumenil, G., Deveaud, C., Miura, M., Coppola, D., DeAngelis, T., Rubin, R., Efstratiadis, A., and Baserga, R. Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts. Mol. Cell. Biol., 14: 3604-3612, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3604-3612
    • Sell, C.1    Dumenil, G.2    Deveaud, C.3    Miura, M.4    Coppola, D.5    DeAngelis, T.6    Rubin, R.7    Efstratiadis, A.8    Baserga, R.9
  • 21
    • 0026031868 scopus 로고
    • Episome-generated N-myc antisense RNA restricts the differentiation potential of primitive neuroectodermal cell lines
    • Whitesell, L., Rosolen, A., and Neckers, L. M. Episome-generated N-myc antisense RNA restricts the differentiation potential of primitive neuroectodermal cell lines. Mol. Cell. Biol., 11: 1360-1371, 1991.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 1360-1371
    • Whitesell, L.1    Rosolen, A.2    Neckers, L.M.3
  • 22
    • 0031909866 scopus 로고    scopus 로고
    • The physical association of multiple molecular chaperone proteins with mutant p53 is altered by geldanamycin, an hsp90-binding agent
    • Whitesell, L., Sutphin, P. D., Pulcini, E. J., Martinez, J. D., and Cook, P. H. The physical association of multiple molecular chaperone proteins with mutant p53 is altered by geldanamycin, an hsp90-binding agent. Mol. Cell. Biol., 18: 1517-1524, 1998.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 1517-1524
    • Whitesell, L.1    Sutphin, P.D.2    Pulcini, E.J.3    Martinez, J.D.4    Cook, P.H.5
  • 23
    • 0029043888 scopus 로고
    • A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V
    • Vermes, I., Haanen, C., Steffens-Nakken, H., and Reutelingsperger, C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V. J. Immunol. Methods, 184: 39-51, 1995.
    • (1995) J. Immunol. Methods , vol.184 , pp. 39-51
    • Vermes, I.1    Haanen, C.2    Steffens-Nakken, H.3    Reutelingsperger, C.4
  • 24
    • 0025415390 scopus 로고
    • Human neuroblastoma tumors correspond to the arrested differentiation of chromaffin adrenal medullary neuroblasts
    • Cooper, M. J., Hutchins, G. M., Cohen, P. S., Helman, L. J., Mennie, R. J., and Israel, M. A. Human neuroblastoma tumors correspond to the arrested differentiation of chromaffin adrenal medullary neuroblasts. Cell Growth Differ., 1: 149-159, 1990.
    • (1990) Cell Growth Differ. , vol.1 , pp. 149-159
    • Cooper, M.J.1    Hutchins, G.M.2    Cohen, P.S.3    Helman, L.J.4    Mennie, R.J.5    Israel, M.A.6
  • 25
    • 0027496895 scopus 로고
    • Mice carrying null mutations of the genes encoding insulin-like growth factor 1 (Igf-1) and type 1 IGF receptor (Igf1r)
    • Liu, J-P., Baker, J., Perkins, A. S., Robertson, E. J., and Efstratiadis, A. Mice carrying null mutations of the genes encoding insulin-like growth factor 1 (Igf-1) and type 1 IGF receptor (Igf1r). Cell, 75: 59-72, 1993.
    • (1993) Cell , vol.75 , pp. 59-72
    • Liu, J.-P.1    Baker, J.2    Perkins, A.S.3    Robertson, E.J.4    Efstratiadis, A.5
  • 26
    • 0025059645 scopus 로고
    • Insulin-like growth factor I supports embryonic nerve cell survival
    • Svrzic, D., and Schubert, D. Insulin-like growth factor I supports embryonic nerve cell survival. Biochem. Biophys. Res. Commun., 172: 54-60, 1990.
    • (1990) Biochem. Biophys. Res. Commun. , vol.172 , pp. 54-60
    • Svrzic, D.1    Schubert, D.2
  • 28
    • 0026012807 scopus 로고
    • Fibroblast growth factor-mediated proliferation of central nervous system precursors depends on endogenous production of insulin-like growth factor I
    • Drago, J., Murphy, M., Carroll, S. M., Harvey, R. P., and Bartlett, P. F. Fibroblast growth factor-mediated proliferation of central nervous system precursors depends on endogenous production of insulin-like growth factor I. Proc. Natl. Acad. Sci. USA, 88: 2199-2203, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 2199-2203
    • Drago, J.1    Murphy, M.2    Carroll, S.M.3    Harvey, R.P.4    Bartlett, P.F.5
  • 29
    • 0028053410 scopus 로고
    • In vivo treatment with antibody against IGF-1 receptor suppresses growth of human rhabdomyosarcoma and down-regulates p34
    • Kalebic, T., Tsokos, M., and Helman, L. J. In vivo treatment with antibody against IGF-1 receptor suppresses growth of human rhabdomyosarcoma and down-regulates p34. Cancer Res., 54: 5531-5534, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 5531-5534
    • Kalebic, T.1    Tsokos, M.2    Helman, L.J.3
  • 30
    • 0023616117 scopus 로고
    • An antibody to the receptor for insulin-like growth factor I inhibits the growth of MCF-7 cells in tissue culture
    • Rohlik, Q., Adams, D., Kull, F., Jr., and Jacobs, S. An antibody to the receptor for insulin-like growth factor I inhibits the growth of MCF-7 cells in tissue culture. Biochem. Biophys. Res. Commun., 149: 276-281, 1987.
    • (1987) Biochem. Biophys. Res. Commun. , vol.149 , pp. 276-281
    • Rohlik, Q.1    Adams, D.2    Kull Jr., F.3    Jacobs, S.4
  • 31
    • 0029096782 scopus 로고
    • Correlation between apoptosis, tumorigenesis, and levels of insulin-like growth factor I receptors
    • Resnicoff, M., Burgaud, J-L., Rotman, H. L., Abraham, D., and Baserga, R. Correlation between apoptosis, tumorigenesis, and levels of insulin-like growth factor I receptors. Cancer Res., 55: 3739-3741, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 3739-3741
    • Resnicoff, M.1    Burgaud, J.-L.2    Rotman, H.L.3    Abraham, D.4    Baserga, R.5
  • 32
    • 0030987783 scopus 로고    scopus 로고
    • Suppression of insulin-like growth factor I receptor by a triple-helix strategy inhibits IGF-I transcription and tumorigenic potential of rat C6 glioblastoma cells
    • Rininsland, F., Johnson, T. R., Chernicky, C. L., Schulze, E., Burfeind, B., Ilan, J., and Ilan, J. Suppression of insulin-like growth factor I receptor by a triple-helix strategy inhibits IGF-I transcription and tumorigenic potential of rat C6 glioblastoma cells. Proc. Natl. Acad. Sci. USA, 94: 5854-5859, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 5854-5859
    • Rininsland, F.1    Johnson, T.R.2    Chernicky, C.L.3    Schulze, E.4    Burfeind, B.5    Ilan, J.6    Ilan, J.7
  • 33
    • 0028265209 scopus 로고
    • Dominant negative inhibition of tumorigenesis in vivo by human insulin-like growth factor-I receptor mutant
    • Prager, D., Li, H. L., Asa, S., and Melmed, S. Dominant negative inhibition of tumorigenesis in vivo by human insulin-like growth factor-I receptor mutant. Proc. Natl. Acad. Sci. USA, 91: 2181-2185, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2181-2185
    • Prager, D.1    Li, H.L.2    Asa, S.3    Melmed, S.4
  • 34
    • 0032101640 scopus 로고    scopus 로고
    • Inhibition of tumorigenesis and induction of apoptosis in human tumor cells by the stable expression of a myristylated COOH terminus of the insulin-like growth factor I receptor
    • Hongo, A., Yumet, G., Resnicoff, M., Romano, G., O'Connor, R., and Baserga, R. Inhibition of tumorigenesis and induction of apoptosis in human tumor cells by the stable expression of a myristylated COOH terminus of the insulin-like growth factor I receptor. Cancer Res., 58: 2477-2484, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 2477-2484
    • Hongo, A.1    Yumet, G.2    Resnicoff, M.3    Romano, G.4    O'Connor, R.5    Baserga, R.6
  • 35
    • 0032006082 scopus 로고    scopus 로고
    • Expression of the insulin-like growth factor 1 receptor C terminus as a myristylated protein leads to induction of apoptosis in tumor cells
    • Liu, Y., Lehar, S., Corvi, C., Payne, G., and O'Connor, R. Expression of the insulin-like growth factor 1 receptor C terminus as a myristylated protein leads to induction of apoptosis in tumor cells. Cancer Res., 58: 570-576, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 570-576
    • Liu, Y.1    Lehar, S.2    Corvi, C.3    Payne, G.4    O'Connor, R.5
  • 37
    • 0027376439 scopus 로고
    • Antisense oligonucleotides as therapeutic agents-Is the bullet really magical?
    • Washington DC
    • Stein, C., and Cheng, Y-C. Antisense oligonucleotides as therapeutic agents-Is the bullet really magical? Science (Washington DC), 261: 1004-1012, 1993.
    • (1993) Science , vol.261 , pp. 1004-1012
    • Stein, C.1    Cheng, Y.-C.2
  • 38
    • 0028332784 scopus 로고
    • Human osteosarcoma cell lines are dependent on insulin-like growth factor for in vitro growth
    • Kappel, C., Velez-Yanguas, M. C., Hirschfeld, S., and Helman, L. J. Human osteosarcoma cell lines are dependent on insulin-like growth factor for in vitro growth. Cancer Res., 54: 2803-2807, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 2803-2807
    • Kappel, C.1    Velez-Yanguas, M.C.2    Hirschfeld, S.3    Helman, L.J.4
  • 39
    • 0031028245 scopus 로고    scopus 로고
    • Identification of domains of the insulin-like growth factor receptor that are required for protection from apoptosis
    • O'Connor, R., Kauffmann-Zeh, A., Liu, Y., Lehar, S., Evan, G. I., Baserga, R., and Blattler, W. A. Identification of domains of the insulin-like growth factor receptor that are required for protection from apoptosis. Mol. Cell. Biol., 17: 427-435, 1997.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 427-435
    • O'Connor, R.1    Kauffmann-Zeh, A.2    Liu, Y.3    Lehar, S.4    Evan, G.I.5    Baserga, R.6    Blattler, W.A.7
  • 40
    • 0031034574 scopus 로고    scopus 로고
    • Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase and Akt
    • Kulik, G., Klippel, A., and Weber, M. J. Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase and Akt. Mol. Cell. Biol., 17: 1595-1606, 1997.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1595-1606
    • Kulik, G.1    Klippel, A.2    Weber, M.J.3
  • 41
    • 0026683954 scopus 로고
    • Insulin-like growth factor-I inhibits apoptosis in IL-3-dependent hemopoietic cells
    • Rodriguez-Tarduchy, G., Collins, M. K. L., Garcia, I., and Lopez-Rivas, A. Insulin-like growth factor-I inhibits apoptosis in IL-3-dependent hemopoietic cells. J. Immunol., 149: 535-540, 1992.
    • (1992) J. Immunol. , vol.149 , pp. 535-540
    • Rodriguez-Tarduchy, G.1    Collins, M.K.L.2    Garcia, I.3    Lopez-Rivas, A.4
  • 42
    • 0028263811 scopus 로고
    • c-myc-induced apoptosis in fibroblasts is inhibited by specific cytokines
    • Harrington, E. A., Bennett, M. R., Fanidi, A., and Evan, G. I. c-myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J., 13: 3286-3295, 1994.
    • (1994) EMBO J. , vol.13 , pp. 3286-3295
    • Harrington, E.A.1    Bennett, M.R.2    Fanidi, A.3    Evan, G.I.4
  • 43
    • 0028852556 scopus 로고
    • Insulin-like growth factor 1 (IGF-I) and the IGF-I receptor prevent etoposide-induced apoptosis
    • Sell, C., Baserga, R., and Rubin, R. Insulin-like growth factor 1 (IGF-I) and the IGF-I receptor prevent etoposide-induced apoptosis. Cancer Res., 55: 303-306, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 303-306
    • Sell, C.1    Baserga, R.2    Rubin, R.3
  • 44
    • 0031014651 scopus 로고    scopus 로고
    • Insulin-like growth factor I inhibits apoptosis using the phosphatidylinositol 3′-kinase and mitogen-activated protein kinase pathways
    • Parrizas, M., Saltiel, A. R., and LeRoith, D. Insulin-like growth factor I inhibits apoptosis using the phosphatidylinositol 3′-kinase and mitogen-activated protein kinase pathways. J. Biol. Chem., 272: 154-161, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 154-161
    • Parrizas, M.1    Saltiel, A.R.2    LeRoith, D.3
  • 46
    • 0029891426 scopus 로고    scopus 로고
    • Direct gene transfer to mouse melanoma by intratumor injection of free DNA
    • Yang, J-P., and Huang, L. Direct gene transfer to mouse melanoma by intratumor injection of free DNA. Gene Ther., 3: 542-547, 1996.
    • (1996) Gene Ther. , vol.3 , pp. 542-547
    • Yang, J.-P.1    Huang, L.2
  • 47
    • 0030855812 scopus 로고    scopus 로고
    • Antisense targeting of basic fibroblast growth factor and fibroblast growth factor receptor-1 in human melanoma blocks intratumoral angiogenesis and tumor growth
    • Wang, Y., and Becker, D. Antisense targeting of basic fibroblast growth factor and fibroblast growth factor receptor-1 in human melanoma blocks intratumoral angiogenesis and tumor growth. Nat. Med., 3: 887-893, 1997.
    • (1997) Nat. Med. , vol.3 , pp. 887-893
    • Wang, Y.1    Becker, D.2
  • 49
    • 0027517321 scopus 로고
    • Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans
    • Nabel, G., Nabel, E., Yang, Z., Fox, B., Plautz, G., Gao, X., Huang, L., Shu, S., Gordon, D., and Chang, A. Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans. Proc. Natl. Acad. Sci. USA, 90: 11307-11311, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11307-11311
    • Nabel, G.1    Nabel, E.2    Yang, Z.3    Fox, B.4    Plautz, G.5    Gao, X.6    Huang, L.7    Shu, S.8    Gordon, D.9    Chang, A.10
  • 50
    • 0031048964 scopus 로고    scopus 로고
    • Engineering herpes simplex virus vectors for gene transfer to neurons
    • Fink, D. J., and Glorioso, J. C. Engineering herpes simplex virus vectors for gene transfer to neurons. Nat. Med., 3: 357-359, 1997.
    • (1997) Nat. Med. , vol.3 , pp. 357-359
    • Fink, D.J.1    Glorioso, J.C.2
  • 52
    • 0031836938 scopus 로고    scopus 로고
    • Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression
    • Melcher, A., Todryk, S., Hardwick, N., Ford, M., Jacobson, M., and Vile, R. G. Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression. Nat. Med., 4: 581-587, 1998.
    • (1998) Nat. Med. , vol.4 , pp. 581-587
    • Melcher, A.1    Todryk, S.2    Hardwick, N.3    Ford, M.4    Jacobson, M.5    Vile, R.G.6
  • 54
    • 0024344233 scopus 로고
    • Temporal changes in the expression of the insulin-like growth factor II gene associated with tissue maturation in the human fetus
    • Camb.
    • Brice, A. L., Cheetham, J. E., Bolton, V. N., Hill, N. C. W., and Schofield, P. N. Temporal changes in the expression of the insulin-like growth factor II gene associated with tissue maturation in the human fetus. Development (Camb.), 106: 543-554, 1989.
    • (1989) Development , vol.106 , pp. 543-554
    • Brice, A.L.1    Cheetham, J.E.2    Bolton, V.N.3    Hill, N.C.W.4    Schofield, P.N.5


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