-
1
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire, A. et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811 (1998). This was the first paper to describe the phenomenon of RNA interference (RNAi).
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
-
2
-
-
0032538391
-
Soaking in the genome sequence
-
Tabara, H., Grishok, A. & Mello, C. Soaking in the genome sequence. Science 282, 430-431 (1998).
-
(1998)
Science
, vol.282
, pp. 430-431
-
-
Tabara, H.1
Grishok, A.2
Mello, C.3
-
3
-
-
0029024475
-
par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
-
Guo, S. & Kemphues, K. J. par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81, 611-620 (1995).
-
(1995)
Cell
, vol.81
, pp. 611-620
-
-
Guo, S.1
Kemphues, K.J.2
-
4
-
-
0033230617
-
PKR; a sentinel kinase for cellular stress
-
Williams, B. R. PKR; a sentinel kinase for cellular stress. Oncogene 18, 6112-6120 (1999).
-
(1999)
Oncogene
, vol.18
, pp. 6112-6120
-
-
Williams, B.R.1
-
5
-
-
0031657551
-
How cells respond to interferons
-
Stark, G. R., Kerr, I. M., Williams, B. R., Silverman, R. H. & Schreiber, R. D. How cells respond to interferons. Annu. Rev. Biochem. 67, 227-264 (1998).
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 227-264
-
-
Stark, G.R.1
Kerr, I.M.2
Williams, B.R.3
Silverman, R.H.4
Schreiber, R.D.5
-
6
-
-
0032417618
-
RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans
-
Montgomery, M. K., Xu, S. & Fire, A. RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans. Proc. Natl Acad. Sci. USA 95, 15502-15507 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 15502-15507
-
-
Montgomery, M.K.1
Xu, S.2
Fire, A.3
-
7
-
-
0032755747
-
RNA interference can target pre-mRNA: Consequences for gene expression in a Caenorhabditis elegans operon
-
Bosher, J. M., Dufourcq, P., Sookhareea, S. & Labouesse, M. RNA interference can target pre-mRNA: consequences for gene expression in a Caenorhabditis elegans operon. Genetics 153, 1245-1256 (1999).
-
(1999)
Genetics
, vol.153
, pp. 1245-1256
-
-
Bosher, J.M.1
Dufourcq, P.2
Sookhareea, S.3
Labouesse, M.4
-
8
-
-
0033634682
-
Functional anatomy of a dsRNA trigger: Differential requirement for the two trigger strands in RNA interference
-
Parrish, S., Fleenor, J., Xu, S., Mello, C. & Fire, A. Functional anatomy of a dsRNA trigger: differential requirement for the two trigger strands in RNA interference. Mol. Cell 6, 1077-1087 (2000).
-
(2000)
Mol. Cell
, vol.6
, pp. 1077-1087
-
-
Parrish, S.1
Fleenor, J.2
Xu, S.3
Mello, C.4
Fire, A.5
-
9
-
-
0031940775
-
Homology-based control of gene expression patterns in transgenic petunia flowers
-
Que, Q. & Jorgensen, R. A. Homology-based control of gene expression patterns in transgenic petunia flowers. Dev. Genet. 22, 100-109 (1998).
-
(1998)
Dev. Genet.
, vol.22
, pp. 100-109
-
-
Que, Q.1
Jorgensen, R.A.2
-
10
-
-
0030220502
-
Chalcone synthase cosuppression phenotypes in petunia flowers: Comparison of sense vs. antisense constructs and single-copy vs. complex T-DNA sequences
-
Jorgensen, R. A., Cluster, P. D., English, J., Que, Q. & Napoli, C. A. Chalcone synthase cosuppression phenotypes in petunia flowers: comparison of sense vs. antisense constructs and single-copy vs. complex T-DNA sequences. Plant Mol. Biol. 31, 957-973 (1996).
-
(1996)
Plant Mol. Biol.
, vol.31
, pp. 957-973
-
-
Jorgensen, R.A.1
Cluster, P.D.2
English, J.3
Que, Q.4
Napoli, C.A.5
-
11
-
-
0033120047
-
An inverted repeat triggers cytosine methylation of identical sequences in Arabidopsis
-
Luff, B., Pawlowski, L. & Bender, J. An inverted repeat triggers cytosine methylation of identical sequences in Arabidopsis. Mol. Cell 3, 505-511 (1999).
-
(1999)
Mol. Cell
, vol.3
, pp. 505-511
-
-
Luff, B.1
Pawlowski, L.2
Bender, J.3
-
12
-
-
0031748054
-
Gene silencing and homology-dependent gene silencing in Arabidopsis: Genetic modifiers and DNA methylation
-
Furner, I. J., Sheikh, M. A. & Collett, C. E. Gene silencing and homology-dependent gene silencing in Arabidopsis: genetic modifiers and DNA methylation. Genetics 149, 651-662 (1998).
-
(1998)
Genetics
, vol.149
, pp. 651-662
-
-
Furner, I.J.1
Sheikh, M.A.2
Collett, C.E.3
-
13
-
-
0034636551
-
Disruption of the plant gene MOM releases transcriptional silencing of methylated genes
-
Amedeo, P., Habu, Y., Afsar, K., Scheid, O. M. & Paszkowski, J. Disruption of the plant gene MOM releases transcriptional silencing of methylated genes. Nature 405, 203-206 (2000).
-
(2000)
Nature
, vol.405
, pp. 203-206
-
-
Amedeo, P.1
Habu, Y.2
Afsar, K.3
Scheid, O.M.4
Paszkowski, J.5
-
14
-
-
0028020672
-
Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation
-
Ingelbrechf, I., Van Houdt, H., Van Montagu, M. & Depicker, A. Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation. Proc. Natl Acad. Sci. USA 91, 10502-10506 (1994).
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 10502-10506
-
-
Ingelbrechf, I.1
Van Houdt, H.2
Van Montagu, M.3
Depicker, A.4
-
15
-
-
0030875953
-
Systemic acquired silencing: Transgene-specific post-transcriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions
-
erratum 17, 2137 (1998)
-
Palauqui, J. C., Elmayan, T., Pollien, J. M. & Vaucheret, H. Systemic acquired silencing: transgene-specific post-transcriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions. EMBO J. 16, 4738-4745 (1997); erratum 17, 2137 (1998).
-
(1997)
EMBO J.
, vol.16
, pp. 4738-4745
-
-
Palauqui, J.C.1
Elmayan, T.2
Pollien, J.M.3
Vaucheret, H.4
-
16
-
-
0030927776
-
Consistent gene silencing in transgenic plants expressing a replicating potato virus X RNA
-
Angell, S. M. & Baulcombe, D. C. Consistent gene silencing in transgenic plants expressing a replicating potato virus X RNA. EMBO J. 16, 3675-3684 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 3675-3684
-
-
Angell, S.M.1
Baulcombe, D.C.2
-
17
-
-
0030835456
-
Cosuppression in Drosophila: Gene silencing of Alcohol dehydrogenase by white-Adh transgenes is Polycomb dependent
-
Pal-Bhadra, M., Bhadra, U. & Birchler, J. A. Cosuppression in Drosophila: gene silencing of Alcohol dehydrogenase by white-Adh transgenes is Polycomb dependent. Cell 90, 479-490 (1997).
-
(1997)
Cell
, vol.90
, pp. 479-490
-
-
Pal-Bhadra, M.1
Bhadra, U.2
Birchler, J.A.3
-
18
-
-
0034234851
-
Transgene-mediated cosuppression in the C. elegans germ line
-
Dernburg, A. F., Zalevsky, J., Colaiacovo, M. P. & Villeneuve, A. M. Transgene-mediated cosuppression in the C. elegans germ line. Genes Dev. 14, 1578-1583 (2000).
-
(2000)
Genes Dev.
, vol.14
, pp. 1578-1583
-
-
Dernburg, A.F.1
Zalevsky, J.2
Colaiacovo, M.P.3
Villeneuve, A.M.4
-
19
-
-
0032905930
-
Transcriptional and posttranscriptional silencing of rodent alpha1(I) collagen by a homologous transcriptionally self-silenced transgene
-
Bahramian, M. B. & Zarbl, H. Transcriptional and posttranscriptional silencing of rodent alpha1(I) collagen by a homologous transcriptionally self-silenced transgene. Mol. Cell. Biol. 19, 274-283 (1999).
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 274-283
-
-
Bahramian, M.B.1
Zarbl, H.2
-
20
-
-
0029934123
-
Transgene silencing of the al-1 gene in vegetative cells of Neurospora is mediated by a cytoplasmic effector and does not depend on DNA-DNA interactions or DNA methylation
-
Cogoni, C. et al. Transgene silencing of the al-1 gene in vegetative cells of Neurospora is mediated by a cytoplasmic effector and does not depend on DNA-DNA interactions or DNA methylation. EMBO J. 15, 3153-3163 (1996).
-
(1996)
EMBO J.
, vol.15
, pp. 3153-3163
-
-
Cogoni, C.1
-
21
-
-
0028286165
-
Expansions of transgene repeats cause heterochromatin formation and gene silencing in Drosophila
-
Dorer, D. R. & Henikoff, S. Expansions of transgene repeats cause heterochromatin formation and gene silencing in Drosophila. Cell 77, 993-1002 (1994).
-
(1994)
Cell
, vol.77
, pp. 993-1002
-
-
Dorer, D.R.1
Henikoff, S.2
-
22
-
-
0033615491
-
A species of small antisense RNA in posttranscriptional gene silencing in plants
-
Hamilton, A. J. & Baulcombe, D. C. A species of small antisense RNA in posttranscriptional gene silencing in plants. Science 286, 950-952 (1999). A potential mediator of post-transcriptional gene silencing (PTGS) was identified for the first time. This small -25-nucleotide RNA has become a hallmark of silencing processes that are mediated by double-stranded (ds) RNA molecules.
-
(1999)
Science
, vol.286
, pp. 950-952
-
-
Hamilton, A.J.1
Baulcombe, D.C.2
-
23
-
-
0034673638
-
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
-
Hammond, S. M., Bernstein, E., Beach, D. & Hannon, G. J. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404, 293-296 (2000). The authors identify a dsRNA-inducible nuclease activity that targets mRNAs for degradation. They also show that this enzyme is associated with -22-nucleotide RNA fragments (guide RNAs) that might determine target specificity.
-
(2000)
Nature
, vol.404
, pp. 293-296
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
24
-
-
0034737298
-
RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
-
Zamore, P. D., Tuschl, T., Sharp, P. A. & Bartel, D. P. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101, 25-33 (2000). By developing their earlier work on an in vitro RNAi system, these authors show that -22-nucleotide guide RNAs can be produced directly from longer dsRNAs in vitro and that target mRNAs are cleaved in response to dsRNAs at -22-nucleotide intervals.
-
(2000)
Cell
, vol.101
, pp. 25-33
-
-
Zamore, P.D.1
Tuschl, T.2
Sharp, P.A.3
Bartel, D.P.4
-
25
-
-
0034609759
-
Evidence that processed small dsRNAs may mediate sequence specific mRNA degradation during RNAi in Drosophila embryos
-
Yang, D., Lu, H. & Erickson, J. W. Evidence that processed small dsRNAs may mediate sequence specific mRNA degradation during RNAi in Drosophila embryos. Curr. Biol. 10, 1191-1200 (2000).
-
(2000)
Curr. Biol.
, vol.10
, pp. 1191-1200
-
-
Yang, D.1
Lu, H.2
Erickson, J.W.3
-
26
-
-
0034596989
-
Transcriptional silencing and promoter methylation triggered by double-stranded RNA
-
Mette, M. F., Aufsatz, W., van der Winden, J., Matzke, M. A. & Matzke, A. J. M. Transcriptional silencing and promoter methylation triggered by double-stranded RNA. EMBO J. 19, 5194-5201 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 5194-5201
-
-
Mette, M.F.1
Aufsatz, W.2
Van Der Winden, J.3
Matzke, M.A.4
Matzke, A.J.M.5
-
27
-
-
0034634360
-
Transgene and transposon silencing in chlamydomonas reinhardtii by a DEAH-Box RNA helicase
-
Wu-Scharf, D., Jeong, B., Zhang, C. & Cerutti, H. Transgene and transposon silencing in chlamydomonas reinhardtii by a DEAH-Box RNA helicase. Science 290, 1159-1163 (2000).
-
(2000)
Science
, vol.290
, pp. 1159-1163
-
-
Wu-Scharf, D.1
Jeong, B.2
Zhang, C.3
Cerutti, H.4
-
28
-
-
0342804533
-
Gene silencing in worms and fungi
-
Catalanotto, C., Azzalin, G., Macino, G. & Cogoni, C. Gene silencing in worms and fungi. Nature 404, 245 (2000).
-
(2000)
Nature
, vol.404
, pp. 245
-
-
Catalanotto, C.1
Azzalin, G.2
Macino, G.3
Cogoni, C.4
-
29
-
-
0034633770
-
AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals
-
Fagard, M., Boutet, S., Morel, J. B., Bellini, C. & Vaucheret, H. AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals. Proc. Natl Acad. Sci. USA 97, 11650-11654 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 11650-11654
-
-
Fagard, M.1
Boutet, S.2
Morel, J.B.3
Bellini, C.4
Vaucheret, H.5
-
30
-
-
0032472373
-
AGO1 defines a novel locus of Arabidopsis controlling leaf development
-
Bohmert, K. et al. AGO1 defines a novel locus of Arabidopsis controlling leaf development. EMBO J. 17, 170-180 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 170-180
-
-
Bohmert, K.1
-
31
-
-
0030755562
-
A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary
-
Lin, H. & Spradling, A. C. A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary. Development 124, 2463-2476 (1997).
-
(1997)
Development
, vol.124
, pp. 2463-2476
-
-
Lin, H.1
Spradling, A.C.2
-
32
-
-
0032510774
-
Molecular cloning and characterization of a rabbit elF2C protein
-
Zou, C., Zhang, Z., Wu, S. & Osterman, J. C. Molecular cloning and characterization of a rabbit elF2C protein. Gene 211, 187-194 (1998).
-
(1998)
Gene
, vol.211
, pp. 187-194
-
-
Zou, C.1
Zhang, Z.2
Wu, S.3
Osterman, J.C.4
-
33
-
-
0032879978
-
GERp95, a membrane-associated protein that belongs to a family of proteins involved in stem cell differentiation
-
Cikaluk, D. E. et al. GERp95, a membrane-associated protein that belongs to a family of proteins involved in stem cell differentiation. Mol. Biol. Cell 10, 3357-3372 (1999).
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 3357-3372
-
-
Cikaluk, D.E.1
-
34
-
-
0034737747
-
Genetic requirements for inheritance of RNAi in C. elegans
-
Grishok, A., Tabara, H. & Mello, C. C. Genetic requirements for inheritance of RNAi in C. elegans. Science 287, 2494-2497 (2000).
-
(2000)
Science
, vol.287
, pp. 2494-2497
-
-
Grishok, A.1
Tabara, H.2
Mello, C.C.3
-
35
-
-
0032717319
-
The rde-1 gene, RNA interference, and transposon silencing in C. elegans
-
Tabara, H. et al. The rde-1 gene, RNA interference, and transposon silencing in C. elegans. Cell 99, 123-132 (1999). With reference 26, this is one of the first reports of the genetic analysis of RNAi in C. elegans. This paper establishes a link between RNAI and transposon silencing and links the ARGONAUTE family of proteins to the silencing process.
-
(1999)
Cell
, vol.99
, pp. 123-132
-
-
Tabara, H.1
-
36
-
-
0032739015
-
Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD
-
Ketting, R. F., Haverkamp, T. H., van Luenen, H. G. & Plasterk, R. H. Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD. Cell 99, 133-141 (1999). Establishes a link between RNAi and transposon silencing and identifies a putative nuclease as an effector of silencing.
-
(1999)
Cell
, vol.99
, pp. 133-141
-
-
Ketting, R.F.1
Haverkamp, T.H.2
Van Luenen, H.G.3
Plasterk, R.H.4
-
37
-
-
0033151822
-
Werner syndrome helicase contains a 5′→3′ exonuclease activity that digests DNA and RNA strands in DNA/DNA and RNA/DNA duplexes dependent on unwinding
-
Suzuki, N., Shiratori, M., Goto, M. & Furuichi, Y. Werner syndrome helicase contains a 5′→3′ exonuclease activity that digests DNA and RNA strands in DNA/DNA and RNA/DNA duplexes dependent on unwinding. Nucleic Acids Res. 27, 2361-2368 (1999).
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 2361-2368
-
-
Suzuki, N.1
Shiratori, M.2
Goto, M.3
Furuichi, Y.4
-
38
-
-
0032545423
-
Werner syndrome protein. II. Characterization of the integral 3′→5′ DNA exonuclease
-
Kamath-Loeb, A. S., Shen, J. C., Loeb, L. A. & Fry, M. Werner syndrome protein. II. Characterization of the integral 3′→5′ DNA exonuclease. J. Biol. Chem. 273, 34145-34150 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34145-34150
-
-
Kamath-Loeb, A.S.1
Shen, J.C.2
Loeb, L.A.3
Fry, M.4
-
39
-
-
0032545515
-
Werner syndrome protein. I. DNA helicase and DNA exonuclease reside on the same polypeptide
-
Shen, J. C. et al. Werner syndrome protein. I. DNA helicase and DNA exonuclease reside on the same polypeptide. J. Biol. Chem. 273, 34139-34144 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34139-34144
-
-
Shen, J.C.1
-
40
-
-
0031686571
-
The premature ageing syndrome protein, WRN, is a 3′→5′ exonuclease
-
Huang, S. et al. The premature ageing syndrome protein, WRN, is a 3′→5′ exonuclease. Nature Genet. 20, 114-116 (1998).
-
(1998)
Nature Genet.
, vol.20
, pp. 114-116
-
-
Huang, S.1
-
41
-
-
0028321487
-
The Tc5 family of transposable elements in Caenorhabditis elegans
-
Collins, J. J. & Anderson, P. The Tc5 family of transposable elements in Caenorhabditis elegans. Genetics 137, 771-781 (1994).
-
(1994)
Genetics
, vol.137
, pp. 771-781
-
-
Collins, J.J.1
Anderson, P.2
-
42
-
-
0034665818
-
A link between RNA interference and nonsense-mediated decay in Caenorhabditis elegans
-
Domeier, M. E. et al. A link between RNA interference and nonsense-mediated decay in Caenorhabditis elegans. Science 289, 1928-1931 (2000).
-
(2000)
Science
, vol.289
, pp. 1928-1931
-
-
Domeier, M.E.1
-
43
-
-
0032771414
-
SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast
-
Page, M. F., Carr, B., Anders, K. R., Grimson, A. & Anderson, P. SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast. Mol. Cell. Biol. 19, 5943-5951 (1999).
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 5943-5951
-
-
Page, M.F.1
Carr, B.2
Anders, K.R.3
Grimson, A.4
Anderson, P.5
-
44
-
-
0033579344
-
Posttranscriptional gene silencing in Neurospora by a RecQ DNA helicase
-
Cogoni, C. & Macino, G. Posttranscriptional gene silencing in Neurospora by a RecQ DNA helicase. Science 286, 2342-2344 (1999).
-
(1999)
Science
, vol.286
, pp. 2342-2344
-
-
Cogoni, C.1
Macino, G.2
-
45
-
-
0029116861
-
Enhancers of glp-1, a gene required for cell-signaling in Caenorhabditis elegans, define a set of genes required for germline development
-
Qiao, L. et al. Enhancers of glp-1, a gene required for cell-signaling in Caenorhabditis elegans, define a set of genes required for germline development. Genetics 141, 551-569 (1995).
-
(1995)
Genetics
, vol.141
, pp. 551-569
-
-
Qiao, L.1
-
46
-
-
0034708215
-
EGO-1 is related to RNA-directed RNA polymerase and functions in germ-line development and RNA interference in C. elegans
-
erratum in 10, R393-R394 (2000)
-
Smardon, A. et al. EGO-1 is related to RNA-directed RNA polymerase and functions in germ-line development and RNA interference in C. elegans. Curr. Biol. 10, 169-178 (2000); erratum in 10, R393-R394 (2000).
-
(2000)
Curr. Biol.
, vol.10
, pp. 169-178
-
-
Smardon, A.1
-
47
-
-
0033551328
-
Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase
-
Cogoni, C. & Macino, G. Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase. Nature 399, 166-169 (1999).
-
(1999)
Nature
, vol.399
, pp. 166-169
-
-
Cogoni, C.1
Macino, G.2
-
48
-
-
0034716924
-
An RNA-dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus
-
Dalmay, T., Hamilton, A., Rudd, S., Angell, S. & Baulcombe, D. C. An RNA-dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus. Cell 101, 543-553 (2000).
-
(2000)
Cell
, vol.101
, pp. 543-553
-
-
Dalmay, T.1
Hamilton, A.2
Rudd, S.3
Angell, S.4
Baulcombe, D.C.5
-
49
-
-
0034716907
-
Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance
-
Mourrain, P. et al. Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance. Cell 101, 533-542 (2000).
-
(2000)
Cell
, vol.101
, pp. 533-542
-
-
Mourrain, P.1
-
50
-
-
0033572660
-
Targeted mRNA degradation by double-stranded RNA in vitro
-
Tuschl, T., Zamore, P. D., Lehmann, R., Bartel, D. P. & Sharp, P. A. Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev. 13, 3191-3197 (1999).
-
(1999)
Genes Dev.
, vol.13
, pp. 3191-3197
-
-
Tuschl, T.1
Zamore, P.D.2
Lehmann, R.3
Bartel, D.P.4
Sharp, P.A.5
-
51
-
-
0034724519
-
Double-stranded RNA as a template for gene silencing
-
Bass, B. L. Double-stranded RNA as a template for gene silencing. Cell 101, 235-238 (2000).
-
(2000)
Cell
, vol.101
, pp. 235-238
-
-
Bass, B.L.1
-
52
-
-
0034306266
-
Domains in gene silencing and cell differentiation proteins: The novel PAZ domain and redefinition of the piwi domain
-
Cerutti, L., Mian, N. & Bateman, A. Domains in gene silencing and cell differentiation proteins: the novel PAZ domain and redefinition of the piwi domain. Trends Biochem. Sci. 10, 481-482 (2000).
-
(2000)
Trends Biochem. Sci.
, vol.10
, pp. 481-482
-
-
Cerutti, L.1
Mian, N.2
Bateman, A.3
-
53
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein, E., Caudy, A. C., Hammond, S. M. & Hannon, G. J. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409, 363-366 (2001).
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.C.2
Hammond, S.M.3
Hannon, G.J.4
-
54
-
-
0034176335
-
Initiation of genetic recombination and recombination-dependent replication
-
Kowalczykowski, S. C. Initiation of genetic recombination and recombination-dependent replication. Trends Biochem. Sci. 25, 156-165 (2000).
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 156-165
-
-
Kowalczykowski, S.C.1
-
55
-
-
0033968037
-
Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes
-
Tavernarakis, N., Wang, S. L., Dorovkov, M., Ryazanov, A. & Driscoll, M. Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes. Nature Genet. 24, 180-183 (2000).
-
(2000)
Nature Genet.
, vol.24
, pp. 180-183
-
-
Tavernarakis, N.1
Wang, S.L.2
Dorovkov, M.3
Ryazanov, A.4
Driscoll, M.5
-
56
-
-
0034676457
-
Functional genomic analysis of C. elegans chromosome I by systematic RNA interference
-
Fraser, A. G. et al. Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature 408, 325-330 (2000).
-
(2000)
Nature
, vol.408
, pp. 325-330
-
-
Fraser, A.G.1
-
57
-
-
0034676448
-
Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III
-
Gonczy, P. et al. Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature 408, 331-336 (2000).
-
(2000)
Nature
, vol.408
, pp. 331-336
-
-
Gonczy, P.1
-
58
-
-
0033883114
-
Heritable gene silencing in Drosophila using double stranded RNA
-
Kennerdell, J. R. & Carthew, R. W. Heritable gene silencing in Drosophila using double stranded RNA. Nature Biotechnol. 17, 896-898 (2000).
-
(2000)
Nature Biotechnol.
, vol.17
, pp. 896-898
-
-
Kennerdell, J.R.1
Carthew, R.W.2
-
59
-
-
0034612276
-
Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways
-
Clemens, J. C. et al. Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways. Proc. Natl Acad. Sci. USA 97, 6499-6503 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 6499-6503
-
-
Clemens, J.C.1
-
60
-
-
0034674713
-
Gene targeting by homologous recombination in Drosophila
-
Rong, Y. S. & Golic, K. G. Gene targeting by homologous recombination in Drosophila. Science 288, 2013-2018 (2000).
-
(2000)
Science
, vol.288
, pp. 2013-2018
-
-
Rong, Y.S.1
Golic, K.G.2
-
61
-
-
0032410928
-
Double-stranded RNA induces mRNA degradation in Trypanosoma brucei
-
Ngo, H., Tschudi, C., Gull, K. & Ullu, E. Double-stranded RNA induces mRNA degradation in Trypanosoma brucei. Proc. Natl Acad. Sci. USA 95, 14687-14692 (1998)
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 14687-14692
-
-
Ngo, H.1
Tschudi, C.2
Gull, K.3
Ullu, E.4
-
62
-
-
0033608994
-
Double stranded RNA specifically disrupts gene expression during planarian regeneration
-
Alvarado, A. S. & Newmark, P. A. Double stranded RNA specifically disrupts gene expression during planarian regeneration. Proc. Natl Acad. Sci. USA 96, 5049-5054 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 5049-5054
-
-
Alvarado, A.S.1
Newmark, P.A.2
-
63
-
-
0033766888
-
Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference
-
Svoboda, P., Stein, P., Hayashi, H. & Schultz, R. M. Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference. Development 127, 4147-4156 (2000).
-
(2000)
Development
, vol.127
, pp. 4147-4156
-
-
Svoboda, P.1
Stein, P.2
Hayashi, H.3
Schultz, R.M.4
-
64
-
-
0033789992
-
Specific interference with gene function by double-stranded RNA in early mouse development
-
Wianny, F. & Zemicka-Goetz, M. Specific interference with gene function by double-stranded RNA in early mouse development. Nature Cell Biol. 2, 70-75 (2000).
-
(2000)
Nature Cell Biol.
, vol.2
, pp. 70-75
-
-
Wianny, F.1
Zemicka-Goetz, M.2
-
65
-
-
0034683099
-
Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target
-
Ui-Tei, K., Zenno, S., Miyata, Y. & Saigo, K. Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target. FEBS Lett. 479, 79-82 (2000).
-
(2000)
FEBS Lett.
, vol.479
, pp. 79-82
-
-
Ui-Tei, K.1
Zenno, S.2
Miyata, Y.3
Saigo, K.4
-
66
-
-
0032757554
-
Cosuppression of I transposon activity in Drosophila by I-containing sense and antisense transgenes
-
Jensen, S., Gassama, M. P. & Heidmann, T. Cosuppression of I transposon activity in Drosophila by I-containing sense and antisense transgenes. Genetics 153, 1767-1774 (1999).
-
(1999)
Genetics
, vol.153
, pp. 1767-1774
-
-
Jensen, S.1
Gassama, M.P.2
Heidmann, T.3
-
67
-
-
0033756232
-
New insights on pomology-dependent silencing of I factor activity by transgenes containing ORF1 in Drosophila melanogaster
-
Malinsky, S., Bucheton, A. & Busseau, I. New insights on pomology-dependent silencing of I factor activity by transgenes containing ORF1 in Drosophila melanogaster. Genetics 156, 1147-1155 (2000).
-
(2000)
Genetics
, vol.156
, pp. 1147-1155
-
-
Malinsky, S.1
Bucheton, A.2
Busseau, I.3
-
68
-
-
0032538794
-
Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana
-
Brigneti, G. et al. Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana. EMBO J. 17, 6739-6746 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 6739-6746
-
-
Brigneti, G.1
-
69
-
-
0033598840
-
Suppression of gene silencing: A general strategy used by diverse DNA and RNA viruses of plants
-
Voinnet, O., Pinto, Y. M. & Baulcombe, D. C. Suppression of gene silencing: a general strategy used by diverse DNA and RNA viruses of plants. Proc. Natl Acad. Sci. USA 96, 14147-14152 (1999). This is one of several papers that establishes a second biological function for RNAi by linking dsRNA-induced silencing to virus resistance in plants.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 14147-14152
-
-
Voinnet, O.1
Pinto, Y.M.2
Baulcombe, D.C.3
-
70
-
-
0031898646
-
Homology-dependent gene silencing in Paramecium
-
Ruiz, F., Vayssie, L., Klotz, C., Sperling, L. & Madeddu, L. Homology-dependent gene silencing in Paramecium. Mol. Biol. Cell 9, 931-943 (1998).
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 931-943
-
-
Ruiz, F.1
Vayssie, L.2
Klotz, C.3
Sperling, L.4
Madeddu, L.5
-
71
-
-
0033928734
-
Genetic interference in Trypanosoma brucei by heritable and indicible double-stranded RNA
-
Shi, H. et al. Genetic interference in Trypanosoma brucei by heritable and indicible double-stranded RNA. RNA 6, 1069-1076 (2000).
-
(2000)
RNA
, vol.6
, pp. 1069-1076
-
-
Shi, H.1
-
72
-
-
0033883114
-
Heritable gene silencing in Drosophila using double-stranded RNA
-
Kennerdell, J. R. & Carthew, R. W. Heritable gene silencing in Drosophila using double-stranded RNA. Nature Biotechnol. 18, 896-898 (2000).
-
(2000)
Nature Biotechnol.
, vol.18
, pp. 896-898
-
-
Kennerdell, J.R.1
Carthew, R.W.2
-
73
-
-
0034650510
-
Double-stranded RNA injection produces null phenotypes in zebrafish
-
erratum 220, 432 (2000)
-
Li, Y. X., Farrell, M. J., Liu, R., Mohanty, N. & Kirby, M. L. Double-stranded RNA injection produces null phenotypes in zebrafish. Dev. Biol. 217, 394-405 (2000); erratum 220, 432 (2000).
-
(2000)
Dev. Biol.
, vol.217
, pp. 394-405
-
-
Li, Y.X.1
Farrell, M.J.2
Liu, R.3
Mohanty, N.4
Kirby, M.L.5
-
74
-
-
0033575910
-
Double-stranded RNA induces specific developmental defects in zebrafish embryos
-
Wargelius, A., Ellingsen, S. & Fjose, A. Double-stranded RNA induces specific developmental defects in zebrafish embryos. Biochem. Biophys. Res. Commun. 263, 156-161 (1999).
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.263
, pp. 156-161
-
-
Wargelius, A.1
Ellingsen, S.2
Fjose, A.3
-
75
-
-
0034254815
-
Too much interference: Injection of double-stranded RNA has nonspecific effects in the zebrafish embryo
-
Oates, A. C., Bruce, A. E. & Ho, R. K. Too much interference: injection of double-stranded RNA has nonspecific effects in the zebrafish embryo. Dev. Biol. 224, 20-28 (2000).
-
(2000)
Dev. Biol.
, vol.224
, pp. 20-28
-
-
Oates, A.C.1
Bruce, A.E.2
Ho, R.K.3
-
76
-
-
0033602489
-
Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis
-
Fraser, A. G., James, C., Evan, G. I. & Hengartner, M. O. Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis. Curr. Biol. 9, 292-301 (1999).
-
(1999)
Curr. Biol.
, vol.9
, pp. 292-301
-
-
Fraser, A.G.1
James, C.2
Evan, G.I.3
Hengartner, M.O.4
-
77
-
-
0033968037
-
Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes
-
Tavernarakis, N., Wang, S. L., Dorovkov, M., Ryazanov, A. & Driscoll, M. Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes. Nature Genet. 24, 180-183 (2000).
-
(2000)
Nature Genet.
, vol.24
, pp. 180-183
-
-
Tavernarakis, N.1
Wang, S.L.2
Dorovkov, M.3
Ryazanov, A.4
Driscoll, M.5
-
78
-
-
0033928734
-
Genetic interference in Trypanosoma brucei by heritable and inducible double-stranded RNA
-
Shi, H. et al. Genetic interference in Trypanosoma brucei by heritable and inducible double-stranded RNA. RNA 6, 1069-1076 (2000).
-
(2000)
RNA
, vol.6
, pp. 1069-1076
-
-
Shi, H.1
-
79
-
-
0034712919
-
Specific and heritable genetic interference by double-stranded RNA in Arabidopsis thaliana
-
Chuang, C. F. & Meyerowitz, E. M. Specific and heritable genetic interference by double-stranded RNA in Arabidopsis thaliana. Proc. Natl Acad. Sci. USA 97, 4985-4990 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 4985-4990
-
-
Chuang, C.F.1
Meyerowitz, E.M.2
-
80
-
-
0034704084
-
Interference of Trypanosoma brucei gene expression by RNA Interference using an integratable vector with opposing T7 promoters
-
Wang, Z., Morris, J. C., Drew, M. E. & England, P. T. Interference of Trypanosoma brucei gene expression by RNA Interference using an integratable vector with opposing T7 promoters. J. Biol. Chem. 275, 40174-40179 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 40174-40179
-
-
Wang, Z.1
Morris, J.C.2
Drew, M.E.3
England, P.T.4
|