Reversal of epidermal hyperproliferation in psoriasis by insulin-like growth factor I receptor antisense oligonucleotides

Nature Biotechnology

Volumn 18, Issue 5, 2000, Pages 521-526

  Wraight, Christopher J ^a   White, Paul J ^a,b   McKean, Sandra C ^a   Fogarty, Rhys D ^a   Venables, Daryl J ^a   Liepe, Ingrid J ^a   Edmondson, Stephanie R ^a   Werther, George A ^a  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Antisense oligonucleotides; Hyperproliferation; IGF I receptor; Keratinocytes; Psoriasis

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; COMPLEMENTARY RNA; DEOXYCYTIDINE; DEOXYURIDINE; KI 67 ANTIGEN; MESSENGER RNA; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; SOMATOMEDIN C RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIVISION; CELL PROLIFERATION; CONTROLLED STUDY; EPIDERMIS CELL; EPIDERMIS HYPERPLASIA; GENE EXPRESSION REGULATION; GENE TARGETING; GENE THERAPY; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PSORIASIS;

ANIMALS; EPIDERMIS; HUMANS; HYPERPLASIA; INJECTIONS, INTRADERMAL; KERATINOCYTES; MICE; MICE, INBRED CBA; MICE, NUDE; OLIGONUCLEOTIDES, ANTISENSE; PSORIASIS; RECEPTOR, IGF TYPE 1; RNA, MESSENGER; SKIN TRANSPLANTATION; TRANSPLANTATION, HETEROLOGOUS;

ANIMALIA; MUS MUSCULUS;

EID: 0034123916     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/75382     Document Type: Article

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