The efficacy of small interfering RNAs targeted to the type 1 insulin-like growth factor receptor (IGF1R) is influenced by secondary structure in the IGF1R transcript

Journal of Biological Chemistry

Volumn 278, Issue 18, 2003, Pages 15991-15997

  Bohula, Erin A ^a   Salisbury, Amanda J ^a   Sohail, Muhammad ^b   Playford, Martin P ^a   Riedemann, Johann ^a   Southern, Edwin M ^b   Macaulay, Valentine M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CYTOLOGY; GENES; ONCOLOGY; TUMORS;

GROWTH FACTOR RECEPTORS;

RNA;

ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; ATM PROTEIN; OLIGONUCLEOTIDE; RNA; SMALL INTERFERING RNA; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG; MESSENGER RNA;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER RADIOTHERAPY; DNA MICROARRAY; DOWN REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; HYBRIDIZATION; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; RADIOSENSITIVITY; RNA SEQUENCE; TUMOR CELL; CELL CULTURE; CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; GENETICS;

GENE SILENCING; HUMANS; NUCLEIC ACID CONFORMATION; RECEPTOR, IGF TYPE 1; RNA, MESSENGER; RNA, SMALL INTERFERING; TUMOR CELLS, CULTURED;

EID: 0038521255     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M300714200     Document Type: Article

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