Decreased expression of the mannose 6- phosphate/insulin-like growth factor-II receptor promotes growth of human breast cancer cells

BMC Cancer

Volumn 2, Issue , 2002, Pages

  Chen, Zhihong ^a   Ge, Yinlin ^a   Landman, Natalie ^a   Kang, Jing X ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; BETA GLUCURONIDASE; MANNOSE 6 PHOSPHATE; MESSENGER RNA; RIBOZYME; SOMATOMEDIN B RECEPTOR; TUMOR NECROSIS FACTOR; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; PHOTOPROTEIN; RADIOACTIVE IODINE; SOMATOMEDIN B; TUMOR NECROSIS FACTOR ALPHA;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER GROWTH; CANCER INHIBITION; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG EFFECT; DRUG TARGETING; GENE EXPRESSION REGULATION; GENE MUTATION; GROWTH RATE; HUMAN; HUMAN CELL; TRANSCRIPTION REGULATION; VIRAL GENE DELIVERY SYSTEM; ADENOVIRUS; BREAST TUMOR; CELL CULTURE; CELL DIVISION; CELL SURVIVAL; GENETIC TRANSFECTION; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; PHYSIOLOGY; PLASMID;

ADENOVIRIDAE; APOPTOSIS; BASE SEQUENCE; BREAST NEOPLASMS; CELL DIVISION; CELL SURVIVAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GREEN FLUORESCENT PROTEINS; HUMANS; INSULIN-LIKE GROWTH FACTOR II; IODINE RADIOISOTOPES; LUMINESCENT PROTEINS; PLASMIDS; RECEPTOR, IGF TYPE 2; RECOMBINANT FUSION PROTEINS; RNA, CATALYTIC; RNA, MESSENGER; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 3042714343     PISSN: 14712407     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2407-2-18     Document Type: Article

References (43)

1. Durfee SM, Selland DL, Smith DN, Lester SC, Kaelin CM, Meyer JE: Sonographic evaluation of clinically palpable breast cancers invisible on mammaography. Breast J 2001, 6:247-251
2. Bange J, Zwick E, Ullrich A: Molecular targets for breast cancer therapy and prevention. Nat Med 2001, 7:548-552
3. Schultz LB, Weber BL: Recent advances in breast cancer biology. Curr Opin Oncol 1999, 11:429-434
4. Boice JD Jr: Radiation and breast carcinogenesis. Med Pediatr Oncol 2001, 36:508-513
5. Ganz PA: The role of hormones in breast carcinogenesis: issues of relevance to female chidhood cancer survivors. Med Pediatr Oncol 2001, 36:514-518
6. Ellis MJ, Jenkins S, Hanfelt J, Redington ME, Taylor M, Leek R, Siddle K, Harris A: Insulin-like growth factors in human breast cancer. Breast Cancer Res Treat 1998, 52:175-184
7. Zhang X, Yee D: Tyrosine kinase signaling in breast cancer: insulin-like growth factors and their receptors in breast cancer. Breast Cancer Res 2000, 2:170-175
8. Yee D, Rosen N, Favoni RE, Cullen KJ: The insulin-like growth factors, their receptors, and their binding proteins in human breast cancer. Cancer Treat Res 1991, 53:93-106
9. Peyrat JP, Bonneterre J, Dusanter-Fourt I, Leroy-Martin B, Demaille DJ: Characterization of insulin-like growth factor 1 receptors (IGF1R) in human breast cancer cell lines. Bull Cancer 1989, 76:311-319
10. Ellis MJC, Leav BA, Yang Z, Rasmussen A, Pearce A, Zweibel JA, Lippman ME, Cullen KJ: Affinity for the insulin-like growth factor-II (IGF-II) receptor inhibits autocrine IGF-II activity in MCF-7 breast cancer cells. Mol Endocrinol 1996, 10:286-297
11. Dennis PA, Rifkin DB: Cellular activation of latent transforming growth factor b requires binding to the cation-independent mannose-6-phosphate/insulin like growth factor type II receptor. Proc Natl Acad Sci 1991, 88:580-584
12. Nolan CM, Sly WS: Intracellular traffic of the mannose 6-phosphate receptor and its ligands. Adv Exp Med Biol 1987, 225:199-212
13. Dams NM, Lobel P, Kornfeld S: Mannose 6-phosphate receptors and lysosomal targeting. J Biol Chem 1989, 264:12115-12118
14. Sue SR, Chari RS, Kong FM, Mils JJ, Fine RL, Jirtle RL, Meyers WC: Transforming growth factor-beta receptors and mannose 6-phosphate/insulin-like growth factor-II receptor expression in human hepatocellular carcinoma. Ann Surg 1995, 222:171-178
15. De Souza AT, Hankins GR, Washington MK, Orton TC, Jirtle RL: M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity. Nat Gen 1995, 11:447-449
16. Chappell SA, Walsh T, Walker RA, Shaw JA: Loss of heterozygosity at the mannose 6-phosphate insulin-like growth factor 2 receptor gene correlates with poor differentiation in early breast carcinomas. Br J Cancer 1997, 76:1558-1561
17. Yamada T, De Souza AT, Finkelstein S, Jirtle RL: Loss of the gene encoding mannose 6-phosphate/insulin-like growth factor II receptor is an early event in liver carcinogenesis. Proc Natl Acad Sci 1997, 94:10351-10355
18. Oates AJ, Schumaker LM, Jenkins SB, Pearce AA, DaCosta SA, Arun B, Ellis MJ: The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R), a putative breast tumor suppressor gene. Breast Cancer Res Treat 1998, 47:269-281
19. DaCosta SA, Schumaker LM, Ellis MJ: Mannose 6-phosphate/insulin-like growth factor 2 receptor, a bona fide tumor suppressor gene or just a promising candidate? Mammary Gland Biol Neoplasia 2000, 5:85-94
20. Hankins GR, De Souza AT, Bentley RC, Patel MR, Marks JR, Iglehart JD, Jirtle RL: M6P/IGF2 receptor: a candidate breast tumor suppressor gene. Oncogene 1996, 12:2003-2009
21. Piao Z, Choi Y, Park C, Lee WJ, Park JH, Kim H: Deletion of the M6P/IGF2R gene in primary hepatocellular carcinoma. Cancer Lett 1997, 120:39-43
22. Mills JJ, Fall JG, De Souza AT, Jirtle RL: Imprinted M6P/IGF2 receptor is mutated in rat liver tumors. Oncogene 1998, 16:2797-2802
23. Gray SG, Eriksson T, Ekstrom C, Holm S, von Schweinitz D, Kogner P, Sandstedt B, Pietsch T, Ekstrom TJ: Altered expression of members of the IGF-axis in hepatoblastomas. Br J Cancer 2000, 82:1561-1567
24. Kong FM, Anscher MS, Washington MK, Killian JK, Jirtle RL: M6P/IGF2R is mutated in squamous cell carcinoma of the lung. Oncogene 2000, 19:1572-1578
25. Bhattacharyya N, Banerjee S: Mutational analysis of TGFβIIR and IGF2R genes in prostate tumors. Proc AACR 1999, 40:Abstract #661
26. Kong FM, Pulford DJ, Bandera M, Anscher MS, Jirtle RL: M6P/IGF2R tumor suppressor is mutated in lung cancer. Proc AACR 1999, 40:Abstract #4839
27. Ouyang H, Shiwaku HO, Hagiwara H, Miura K, Abe T, Kato Y, Ohtani H, Shiiba K, Souza RF, Meltzer SJ, Horii A: The insulin-like growth factor II receptor gene is mutated in genetically unstable cancers of endometrium, stomach and cholorectum. Cancer Res 1997, 57:1851-1854
28. Gemma A, Uematsu K, Hagiwara K, Takenoshita S, Kudoh S: Mechanism of resistance to growth inhibition by transforming growth factor-beta 1(TGF-beta 1) in primary lung cancer and new molecular targets in therapy. Gan To Kagaku Ryoho 2000, 27:1253-1259
29. Kaplan PJ, Mohan S, Cohen P, Foster BA, Greenberg NM: The insulin-like growth factor axis and prostate cancer: lessons from the transgenic adenocarcinoma of mouse prostate (TRAMP) model. Cancer Res 1999, 59:2203-2209
30. He TC, Zhou S, Da Costa LT, Yu J, Kinzler KW, Vogelstein B: A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci 1995, 95:2509-2514
31. Minniti CP, Koho EC, Grubb JH, Sly WS, Oh Y, Muller HI, Rosenfeld RG, Helman LJ: The insulin-like growth factorII (IGF-II)/mannose 6-phosphate receptor mediates IGF-II- induced motility in human rhabdomyosrcoma cells. J Biol Chem 1992, 267:9000-9004
32. Szebenyi G, Rotwein P: Differential regulation of mannose 6-phosphate receptors and their ligands during the myogenic development of C2 cells. J Biol Chem 1991, 266:5534-5539
33. Oshima A, Nolan CM, Kyle JW, Grubb JH, Sly WS: The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells. J Biol Chem 1988, 263:2553-2562
34. Lau MM, Stewart CE, Liu Z, Bhatt H, Rotwein P, Stewart CL: Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality. Genes Dev 1994, 8:2953-2963
35. Deiss LP, Galinka H, Berissi H, Cohen O, Kimchi A: Cathepsin D protease mediates programmed cell death induced by inter-feron-γ, Fas/APO-1, and TNF-α. EMBO J 1996, 15:3861-3870
36. Roberts LR, Adjei PN, Gores GJ: Cathepsins as effector proteases in hepatocyte apoptosis. Cell Biochem Biophys 1999, 30:71-88
37. Roberg K, Ollinger K: Oxidative stress causes relocation of lysosomal cathepsin D with ensuing apoptosis in neonatal rat cardiomyocytes. Am J Pathol 1998, 152:1151-1156
38. Foghsgaard L, Wissing D, Mauch D, Lademann U, Bastholm L, Boes M, Elling F, Leist M, Jaatela M: Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor. J Cell Bio 2001, 153:999-1010
39. Guicciardi ME, Miyoshi H, Bronk SF, Gores GJ: Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha-mediated hepatocyte apoptosis and liver injury: implications for therapeutic applications. Am J Pathol 2001, 159:2045-2054
40. Chao CC, Hu S, Sheng WS, Tsang M, Peterson PK: Tumor necrosis factor-alpha mediates the release of bioactive transforming growth factor-beta in murine microglial cell cultures. Clin Immunol Immunopathol 1995, 77:358-365
41. Danforth DN Jr, Sgagias MK: Tumor necrosis factor alpha enhances secretion of transforming growth factor beta in MCF-7 breast cancer cells. Clin Cancer Res 1996, 2:827-835
42. Tobin SW, Brown MK, Douville K, Payne DC, Eastman A, Arrick BA: Inhibition of transforming growth factor β signaling in MCF-7 cells results in resistance to tumor necrosis factor α: a role for Bcl-2. Cell Growth Diff 2001, 12:109-117
43. O'Gorman DB, Costello M, Weiss J, Firth SM, Scott CD: Decreased insulin-like growth factor-II/mannose 6-phosphate receptor expression enhances tumorigenicity in JEG-3 cells. Cancer Res 1999, 59:5692-5694