Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rat and human hepatocytes

Carcinogenesis

Volumn 23, Issue 1, 2002, Pages 115-122

  Langouët, Sophie ^a   Paehler, Axel ^b   Welti, Dieter H ^b   Kerriguy, Nathalie ^a   Guillouzo, André ^a   Turesky, Robert J ^b,c  

^a UNIVERSITÉ DE RENNES 1   (France)

^b NESTLÉ RESEARCH CENTER   (Switzerland)

^c NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; 2 AMINO 4' HYDROXY 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; 2 HYDROXYAMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; 3 METHYLCHOLANTHRENE; 4' HYDROXY 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; CYTOCHROME P450 1A1; FURAFYLLINE; GLUCURONIDE; GLUCURONOSYLTRANSFERASE; LIVER ENZYME; NITROGEN; PYRIDINE DERIVATIVE; SULFATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOTRANSFORMATION; CATALYSIS; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CONJUGATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; GENOTOXICITY; GLUCURONIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROXYLATION; ISOMER; LIVER METABOLISM; MALE; MASS SPECTROMETRY; MOLECULAR STABILITY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE; ULTRAVIOLET SPECTROSCOPY;

EID: 0036197494     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/23.1.115     Document Type: Article

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