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Volumn 109, Issue 1-2, 1996, Pages 185-191

Protective effect of rutin, a flavonol glycoside, on the carcinogen-induced DNA damage and repair enzymes in rats

Author keywords

Aflatoxin B1; DNA damage; DNA repair enzymes; N nitrosodimethylamine; Protective role; Rutin

Indexed keywords

AFLATOXIN B1; CARCINOGEN; CELL NUCLEUS DNA; DIMETHYLNITROSAMINE; DNA DIRECTED DNA POLYMERASE BETA; FLAVONOL; GLYCOSIDE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; RUTOSIDE;

EID: 0008345428     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(96)04443-6     Document Type: Article
Times cited : (92)

References (51)
  • 1
    • 0024364268 scopus 로고
    • Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation
    • [1] Afanasiev, I.B., Dorozhko, A.I., Brodshi, A.V., Kostyak, V.A. and Potaporitch, A.I. (1989) Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation. Biochem. Pharmacol., 38, 1763-1769.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 1763-1769
    • Afanasiev, I.B.1    Dorozhko, A.I.2    Brodshi, A.V.3    Kostyak, V.A.4    Potaporitch, A.I.5
  • 4
    • 0011364304 scopus 로고
    • Interaction of polyphenols with microsomal monooxygenase during carcinogen activation
    • Université Louis Pasteur, Strasbourg
    • [4] Bhattacharya, R.K. and Firozi, P.F. (1990) Interaction of polyphenols with microsomal monooxygenase during carcinogen activation. In: Groupe Polyphenol, Vol. 15, Proc. XVth Int. Conf., pp. 179-184. Université Louis Pasteur, Strasbourg.
    • (1990) Groupe Polyphenol, Vol. 15, Proc. XVth Int. Conf. , pp. 179-184
    • Bhattacharya, R.K.1    Firozi, P.F.2
  • 5
    • 0014032729 scopus 로고
    • Nuclei from rat liver: Isolation method that combines purity with high yield
    • [5] Blobber, G. and Potter, V.R. (1966) Nuclei from rat liver: isolation method that combines purity with high yield. Science, 154, 1662-1665.
    • (1966) Science , vol.154 , pp. 1662-1665
    • Blobber, G.1    Potter, V.R.2
  • 6
    • 0023584574 scopus 로고
    • Heterogeneous DNA damage and repair in the mammalian genome
    • [6] Bohr, V.A., Phillips, D.H. and Hanawalt, P.C. (1987) Heterogeneous DNA damage and repair in the mammalian genome. Cancer Res., 47, 6426-6436.
    • (1987) Cancer Res. , vol.47 , pp. 6426-6436
    • Bohr, V.A.1    Phillips, D.H.2    Hanawalt, P.C.3
  • 7
    • 0025743868 scopus 로고
    • Relationship between carcinogenesis, chromatin structure and poly(ADP-ribosylation)
    • [7] Boulikas, T. (1991) Relationship between carcinogenesis, chromatin structure and poly(ADP-ribosylation). Anticancer Res., 11, 489-528.
    • (1991) Anticancer Res. , vol.11 , pp. 489-528
    • Boulikas, T.1
  • 8
    • 0022492499 scopus 로고
    • DNA strand breaks, NAD metabolism and programmed cell death
    • [8] Carson, D.A., Sato, S., Wasson, D.B. and Carrera, C.J. (1986) DNA strand breaks, NAD metabolism and programmed cell death. Exp. Cell Res., 164, 273-281.
    • (1986) Exp. Cell Res. , vol.164 , pp. 273-281
    • Carson, D.A.1    Sato, S.2    Wasson, D.B.3    Carrera, C.J.4
  • 9
    • 0025999998 scopus 로고
    • Effects of synthetic and naturally occurring flavonoids on benzo[a]pyrene metabolism by hepatic microsomes prepared from rats treated with cytochrome P-450 inducers
    • [9] Chae, Y.H., Marcus, C.B., Ho, D.K., Cassidy, J.M. and Baird, W.M. (1991) Effects of synthetic and naturally occurring flavonoids on benzo[a]pyrene metabolism by hepatic microsomes prepared from rats treated with cytochrome P-450 inducers. Cancer Lett., 60, 15-24.
    • (1991) Cancer Lett. , vol.60 , pp. 15-24
    • Chae, Y.H.1    Marcus, C.B.2    Ho, D.K.3    Cassidy, J.M.4    Baird, W.M.5
  • 10
    • 0022255969 scopus 로고
    • Effect of ellagic acid and hydroxylated flavonoids on the tumorigenicity of benzo[a]pyrene and (±)7β,8a-dihydroxy-9a,10a-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene on mouse skin and in the newborn mouse
    • [10] Chang, R.L., Huang, M.-T., Wood, A.C., Wong, C.-Q., Newmark, H.L., Yagi, H., Sayer, J.M., Jerina, D.M. and Conney, A.H. (1985) Effect of ellagic acid and hydroxylated flavonoids on the tumorigenicity of benzo[a]pyrene and (±)7β,8a-dihydroxy-9a,10a-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene on mouse skin and in the newborn mouse. Carcinogenesis, 6, 1127-1133.
    • (1985) Carcinogenesis , vol.6 , pp. 1127-1133
    • Chang, R.L.1    Huang, M.-T.2    Wood, A.C.3    Wong, C.-Q.4    Newmark, H.L.5    Yagi, H.6    Sayer, J.M.7    Jerina, D.M.8    Conney, A.H.9
  • 12
    • 0025969111 scopus 로고
    • Poly(ADP-ribose) polymerase: Perplexing participant in cellular responses to DNA breakage
    • [12] Cleaver, J.E. and Morgan, W.F. (1991) Poly(ADP-ribose) polymerase: perplexing participant in cellular responses to DNA breakage. Mutat. Res., 267, 1-18.
    • (1991) Mutat. Res. , vol.267 , pp. 1-18
    • Cleaver, J.E.1    Morgan, W.F.2
  • 13
    • 0015902236 scopus 로고
    • Method for measuring DNA damage and repair in the liver in vivo
    • [13] Cox, R., Damanjanov, I., Abnobi, S.E. and Sarma, D.S.R. (1975) Method for measuring DNA damage and repair in the liver in vivo. Cancer Res., 33, 2114-2121.
    • (1975) Cancer Res. , vol.33 , pp. 2114-2121
    • Cox, R.1    Damanjanov, I.2    Abnobi, S.E.3    Sarma, D.S.R.4
  • 14
    • 0027939130 scopus 로고
    • Chemopreventive potential of dietary bioflavonoids against 20-methylcholanthrene-induced tumorigenesis
    • [14] Elangova, V., Sekar, N. and Govindswamy, S. (1994) Chemopreventive potential of dietary bioflavonoids against 20-methylcholanthrene-induced tumorigenesis. Cancer Lett., 87, 107-113.
    • (1994) Cancer Lett. , vol.87 , pp. 107-113
    • Elangova, V.1    Sekar, N.2    Govindswamy, S.3
  • 17
    • 0025685663 scopus 로고
    • 1 activation in human liver microsomes by naringenin and other flavonoids
    • 1 activation in human liver microsomes by naringenin and other flavonoids. Carcinogenesis, 11, 2275-2279.
    • (1990) Carcinogenesis , vol.11 , pp. 2275-2279
    • Guengerich, F.P.1    Kim, D.H.2
  • 19
    • 31544459003 scopus 로고
    • Desmutagens and bioantimutagens: Their action mechanisms and possible role in the modulation of dose relationships
    • Editors: Y. Tazima, S. Kondo and Y. Kuroda. Environmental Mutagen Society of Japan, Mishima, Japan
    • [19] Kada, T. (1984) Desmutagens and bioantimutagens: their action mechanisms and possible role in the modulation of dose relationships. In: Problems of Threshold in Chemical Mutagenesis, pp. 73-82. Editors: Y. Tazima, S. Kondo and Y. Kuroda. Environmental Mutagen Society of Japan, Mishima, Japan.
    • (1984) Problems of Threshold in Chemical Mutagenesis , pp. 73-82
    • Kada, T.1
  • 20
    • 0028518884 scopus 로고
    • Protection from UV-B induced DNA damage by flavonoids
    • [20] Kootstra, A. (1994) Protection from UV-B induced DNA damage by flavonoids. Plant Mol. Biol., 26, 771-774.
    • (1994) Plant Mol. Biol. , vol.26 , pp. 771-774
    • Kootstra, A.1
  • 21
    • 0015009451 scopus 로고
    • X-ray induced single strand breaks in DNA of E. coli B/r: Effect of irradiation and postirradiation conditions
    • [21] Lehnert, S. and Moroson, H. (1971) X-ray induced single strand breaks in DNA of E. coli B/r: effect of irradiation and postirradiation conditions. Radiat. Res., 4, 299-310.
    • (1971) Radiat. Res. , vol.4 , pp. 299-310
    • Lehnert, S.1    Moroson, H.2
  • 22
    • 0021088294 scopus 로고
    • Protective effects of ellagic acid and other plant phenols on benzo[a]pyrene-induced neoplasia in mice
    • [22] Lesca, P. (1983) Protective effects of ellagic acid and other plant phenols on benzo[a]pyrene-induced neoplasia in mice. Carcinogenesis, 4, 1651-1653.
    • (1983) Carcinogenesis , vol.4 , pp. 1651-1653
    • Lesca, P.1
  • 24
    • 0024433167 scopus 로고
    • Modified mutagen activation in hepatic fraction from rats for dietary rutin interaction between gut flora and host metabolism
    • [24] Mallet, A.K, Bourne, C.A, Lake, B.G. and Rowland, I.R. (1989) Modified mutagen activation in hepatic fraction from rats for dietary rutin interaction between gut flora and host metabolism. Food Chem. Toxicol., 77, 607-611.
    • (1989) Food Chem. Toxicol. , vol.77 , pp. 607-611
    • Mallet, A.K.1    Bourne, C.A.2    Lake, B.G.3    Rowland, I.R.4
  • 25
    • 0019829342 scopus 로고
    • Mechanisms of chemical carcinogenesis
    • [25] Miller, E.C. and Miller, J.A, (1981) Mechanisms of chemical carcinogenesis. Cancer, 47, 1055-1084.
    • (1981) Cancer , vol.47 , pp. 1055-1084
    • Miller, E.C.1    Miller, J.A.2
  • 26
    • 0021271932 scopus 로고
    • Protection against 3-methylcholanthrene induced skin tumorigenesis in BALB/c mice by ellagic acid
    • [26] Mukhtar, H., DelTito, B.J. and Bickers, D.R. (1984) Protection against 3-methylcholanthrene induced skin tumorigenesis in BALB/c mice by ellagic acid. Biochem. Biophys. Res. Commun., 118, 751-757.
    • (1984) Biochem. Biophys. Res. Commun. , vol.118 , pp. 751-757
    • Mukhtar, H.1    DelTito, B.J.2    Bickers, D.R.3
  • 28
    • 0025700717 scopus 로고
    • Differential inhibitory effects of various flavonoids on the activities of reverse transcriptase and cellular DNA and RNA polymerases
    • [28] Ono, K., Nakane, H., Fukushima, M., Chermann, J.-C. and Barre-Sinoussi, F. (1990) Differential inhibitory effects of various flavonoids on the activities of reverse transcriptase and cellular DNA and RNA polymerases. Eur. J. Biochem., 190, 469-478.
    • (1990) Eur. J. Biochem. , vol.190 , pp. 469-478
    • Ono, K.1    Nakane, H.2    Fukushima, M.3    Chermann, J.-C.4    Barre-Sinoussi, F.5
  • 29
    • 0016753985 scopus 로고
    • Alkaline lysis of mammalian cells for sedimentation analysis of nuclear DNA, conformation of released DNA as monitored by physical, electron microscopic and enzymological techniques
    • [29] Parodi, S., Mulevor, R.A., Martin, J.T., Nicolini, C., Sarma, D.S.R. and Farber, E. (1975) Alkaline lysis of mammalian cells for sedimentation analysis of nuclear DNA, conformation of released DNA as monitored by physical, electron microscopic and enzymological techniques. Biochim. Biophys. Acta, 407, 174-190.
    • (1975) Biochim. Biophys. Acta , vol.407 , pp. 174-190
    • Parodi, S.1    Mulevor, R.A.2    Martin, J.T.3    Nicolini, C.4    Sarma, D.S.R.5    Farber, E.6
  • 31
    • 0022886526 scopus 로고
    • Modulation by plant flavonoids and related phenolics of microsome catalyzed adduct formation between benzo[a]pyrene and DNA
    • [31] Shah, G.M. and Bhattacharya, R.K. (1986) Modulation by plant flavonoids and related phenolics of microsome catalyzed adduct formation between benzo[a]pyrene and DNA. Chem.-Biol. Interact., 59, 1-15.
    • (1986) Chem.-Biol. Interact. , vol.59 , pp. 1-15
    • Shah, G.M.1    Bhattacharya, R.K.2
  • 32
    • 0026566367 scopus 로고
    • Dietary modification of drug metabolising enzyme activities: Dose response effects of flavonoids
    • [32] Siess, M.H., Le Bon, A.M. and Suschetet, M. (1992) Dietary modification of drug metabolising enzyme activities: dose response effects of flavonoids. J. Toxicol. Environ. Health, 35, 141-152.
    • (1992) J. Toxicol. Environ. Health , vol.35 , pp. 141-152
    • Siess, M.H.1    Le Bon, A.M.2    Suschetet, M.3
  • 33
    • 0020488542 scopus 로고
    • Nuclear matrix-bound deoxyribonucleic acid synthesis: An in vitro system
    • [33] Smith, C.A. and Berezney, R. (1982) Nuclear matrix-bound deoxyribonucleic acid synthesis: an in vitro system. Biochemistry, 21, 6751-6761.
    • (1982) Biochemistry , vol.21 , pp. 6751-6761
    • Smith, C.A.1    Berezney, R.2
  • 34
    • 0016426048 scopus 로고
    • Release of template restriction for DNA synthesis by poly(ADP-ribose) polymerase during the HeLa cell cycle
    • [34] Smulson, M.E., Stark. P., Gazzoti, M. and Roberts, J. (1975) Release of template restriction for DNA synthesis by poly(ADP-ribose) polymerase during the HeLa cell cycle. Exp. Cell Res., 90, 175-182.
    • (1975) Exp. Cell Res. , vol.90 , pp. 175-182
    • Smulson, M.E.1    Stark, P.2    Gazzoti, M.3    Roberts, J.4
  • 35
    • 0002076773 scopus 로고
    • Flavonoids in foods: Their significance for nutrition and health
    • Editors: A.S.H. Ong and L. Packer. Birkhauser Verlag, Basel
    • [35] Starvic, B. and Matula, T.I. (1992) Flavonoids in foods: their significance for nutrition and health. In: Lipid Soluble Antioxidants, Biochemistry and Clinical Application, pp. 275-292. Editors: A.S.H. Ong and L. Packer. Birkhauser Verlag, Basel.
    • (1992) Lipid Soluble Antioxidants, Biochemistry and Clinical Application , pp. 275-292
    • Starvic, B.1    Matula, T.I.2
  • 36
    • 0021227345 scopus 로고
    • Naturally occurring phenolics as antimutagenic and anticarcinogenic agents
    • Editor: M. Friedman. Plenum Press, New York
    • [36] Stich, H.F. and Powrie, W.D, (1984) Naturally occurring phenolics as antimutagenic and anticarcinogenic agents. In: Nutritional and Toxicological Aspects of Food Safety, pp. 1-29. Editor: M. Friedman. Plenum Press, New York.
    • (1984) Nutritional and Toxicological Aspects of Food Safety , pp. 1-29
    • Stich, H.F.1    Powrie, W.D.2
  • 37
    • 0020354089 scopus 로고
    • Fluorometric quantitation of single-stranded DNA: A method applicable to the technique of alkaline elution
    • [37] Stout, D.L. and Becker, F.F. (1982) Fluorometric quantitation of single-stranded DNA: a method applicable to the technique of alkaline elution. Anal. Biochem., 127, 302-307.
    • (1982) Anal. Biochem. , vol.127 , pp. 302-307
    • Stout, D.L.1    Becker, F.F.2
  • 40
    • 0017197097 scopus 로고
    • Cocarcinogenic and tumor promoting agents in tobacco carcinogenesis
    • [40] van Duuren, B.L. and Goldschmidt, B.M. (1976) Cocarcinogenic and tumor promoting agents in tobacco carcinogenesis. J. Natl. Cancer Inst., 56, 1237-1242.
    • (1976) J. Natl. Cancer Inst. , vol.56 , pp. 1237-1242
    • Van Duuren, B.L.1    Goldschmidt, B.M.2
  • 41
    • 0001163740 scopus 로고
    • Inhibition of carcinogenesis
    • Editors: A.C. Griffin and C.R. Shaw. Raven Press, New York
    • [41] Wattenberg, L.W. (1979) Inhibition of carcinogenesis. In: Carcinogens: Identification and Mechanisms of Action, pp. 229-316. Editors: A.C. Griffin and C.R. Shaw. Raven Press, New York.
    • (1979) Carcinogens: Identification and Mechanisms of Action , pp. 229-316
    • Wattenberg, L.W.1
  • 42
    • 0018857411 scopus 로고
    • Inhibitory effects of phenolic compounds on benzo[a]pyrene induced neoplasia
    • [42] Wattenberg, L.W., Coccia, J.B. and Lam, L.K.J. (1980) Inhibitory effects of phenolic compounds on benzo[a]pyrene induced neoplasia. Cancer Res., 40, 2820-2823.
    • (1980) Cancer Res. , vol.40 , pp. 2820-2823
    • Wattenberg, L.W.1    Coccia, J.B.2    Lam, L.K.J.3
  • 43
    • 0014825026 scopus 로고
    • Inhibition of carcinogenic action of benzo[a]pyrene by flavones
    • [43] Wattenberg, L.W. and Leong, J.L. (1970) Inhibition of carcinogenic action of benzo[a]pyrene by flavones. Cancer Res., 30, 1922-1925.
    • (1970) Cancer Res. , vol.30 , pp. 1922-1925
    • Wattenberg, L.W.1    Leong, J.L.2
  • 44
    • 0029242342 scopus 로고
    • Activity of some nuclear enzymes associated with DNA repair following hepatocarcinogen administration to rats
    • [44] Webster, R.P. and Bhattacharya, R.K. (1995) Activity of some nuclear enzymes associated with DNA repair following hepatocarcinogen administration to rats. J. Biochem. Toxicol., 10, 33-40.
    • (1995) J. Biochem. Toxicol. , vol.10 , pp. 33-40
    • Webster, R.P.1    Bhattacharya, R.K.2
  • 45
    • 0029937344 scopus 로고    scopus 로고
    • Effect of different vitamin A status on carcinogen-induced DNA damage and repair enzymes in rats
    • [45] Webster, R.P., Gawde, M.D. and Bhattacharya, R.K. (1996) Effect of different vitamin A status on carcinogen-induced DNA damage and repair enzymes in rats. In Vivo, 10, 113-118.
    • (1996) In Vivo , vol.10 , pp. 113-118
    • Webster, R.P.1    Gawde, M.D.2    Bhattacharya, R.K.3
  • 46
    • 0030031893 scopus 로고    scopus 로고
    • Modulation of carcinogen-induced DNA damage and repair enzyme activity by dietary riboflavin
    • [46] Webster, R.P., Gawde, M.D. and Bhattacharya, R.K. (1996) Modulation of carcinogen-induced DNA damage and repair enzyme activity by dietary riboflavin. Cancer Lett., 98, 129-135.
    • (1996) Cancer Lett. , vol.98 , pp. 129-135
    • Webster, R.P.1    Gawde, M.D.2    Bhattacharya, R.K.3
  • 47
    • 0029910293 scopus 로고    scopus 로고
    • 1-induced activity of DNA repair enzymes poly(ADP-ribose) polymerase, DNA polymerase β and DNA ligase
    • in press
    • 1-induced activity of DNA repair enzymes poly(ADP-ribose) polymerase, DNA polymerase β and DNA ligase. In Vivo, in press.
    • (1996) In Vivo
    • Webster, R.P.1    Gawde, M.D.2    Bhattacharya, R.K.3
  • 49
    • 0016721868 scopus 로고
    • Stimulation of poly(ADP-ribose) polymerase activity by antitumor antibiotic streptozotocin
    • [49] Whish, W.I.D., Davis, M.I and Shall, S. (1975) Stimulation of poly(ADP-ribose) polymerase activity by antitumor antibiotic streptozotocin. Biochim. Biophys. Res. Commun., 65, 722-730.
    • (1975) Biochim. Biophys. Res. Commun. , vol.65 , pp. 722-730
    • Whish, W.I.D.1    Davis, M.I.2    Shall, S.3
  • 50
    • 0016428160 scopus 로고
    • A deoxyribonucleic acid ligase from nuclei of rat liver
    • [50] Zimmerman, S.B. and Levin, C.J. (1975) A deoxyribonucleic acid ligase from nuclei of rat liver. J. Biol Chem., 250, 149-155.
    • (1975) J. Biol Chem. , vol.250 , pp. 149-155
    • Zimmerman, S.B.1    Levin, C.J.2
  • 51
    • 0017230132 scopus 로고
    • A non-radioactive method for measuring DNA damage and repair in non-proliferating tissues
    • [51] Zubroff, J. and Sarma, D.S.R. (1976) A non-radioactive method for measuring DNA damage and repair in non-proliferating tissues. Anal. Biochem., 70, 387-396.
    • (1976) Anal. Biochem. , vol.70 , pp. 387-396
    • Zubroff, J.1    Sarma, D.S.R.2


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